Identification of potent and novel α4β1 antagonists using in silico screening

Journal of Medicinal Chemistry

Volumn 45, Issue 14, 2002, Pages 2988-2993

  Singh, Juswinder ^a   Abraham, William M ^b   Adams, Steven P ^a   Van Vlijmen, Herman ^a   Liao, Yusheng ^a   Lee, Wen Cherng ^a   Cornebise, Mark ^a   Harris, Mary ^a   Shu, I Hsiang ^a   Gill, Alan ^a   Cuervo, Julio H ^a  

^a BIOGEN   (United States)

^b MOUNT SINAI MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4 [N' (2 METHYLPHENYL)UREIDO]PHENYLACETYLLEUCINYLASPARAGINYLVALINE; ANTIASTHMATIC AGENT; BETA1 INTEGRIN; CARBACHOL; FIBRONECTIN; UNCLASSIFIED DRUG; VERY LATE ACTIVATION ANTIGEN 4 ANTAGONIST;

ARTICLE; ASTHMA; DRUG SYNTHESIS; INFLAMMATION; PHARMACOPHORE; PROTON NUCLEAR MAGNETIC RESONANCE; QUANTITATIVE STRUCTURE ACTIVITY RELATION; SHEEP;

ADMINISTRATION, INHALATION; AEROSOLS; ANIMALS; ASTHMA; BRONCHIAL HYPERREACTIVITY; BRONCHOCONSTRICTION; COMBINATORIAL CHEMISTRY TECHNIQUES; CRYSTALLOGRAPHY, X-RAY; DATABASES, FACTUAL; FIBRONECTINS; INTEGRIN ALPHA4BETA1; INTEGRINS; MODELS, MOLECULAR; OLIGOPEPTIDES; PHENYLUREA COMPOUNDS; QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIP; RECEPTORS, LYMPHOCYTE HOMING; SHEEP; VASCULAR CELL ADHESION MOLECULE-1;

EID: 0037019269     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm020054e     Document Type: Article

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