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Volumn 10, Issue 6, 2006, Pages 707-718

The G Protein Gα13 Is Required for Growth Factor-Induced Cell Migration

Author keywords

CELLBIO; SIGNALING

Indexed keywords

G PROTEIN COUPLED RECEPTOR; GROWTH FACTOR; GUANINE NUCLEOTIDE BINDING PROTEIN ALPHA SUBUNIT; MUTANT PROTEIN; PROTEIN TYROSINE KINASE; RAC PROTEIN; RECEPTOR SUBTYPE;

EID: 33646859037     PISSN: 15345807     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.devcel.2006.03.014     Document Type: Article
Times cited : (67)

References (72)
  • 1
    • 0035958899 scopus 로고    scopus 로고
    • Tethering of the platelet-derived growth factor β receptor to G-protein-coupled receptors. A novel platform for integrative signaling by these receptor classes in mammalian cells
    • Alderton F., Rakhit S., Kong K.C., Palmer T., Sambi B., Pyne S., and Pyne N.J. Tethering of the platelet-derived growth factor β receptor to G-protein-coupled receptors. A novel platform for integrative signaling by these receptor classes in mammalian cells. J. Biol. Chem. 276 (2001) 28578-28585
    • (2001) J. Biol. Chem. , vol.276 , pp. 28578-28585
    • Alderton, F.1    Rakhit, S.2    Kong, K.C.3    Palmer, T.4    Sambi, B.5    Pyne, S.6    Pyne, N.J.7
  • 2
    • 0022470480 scopus 로고
    • Induction of membrane ruffling and fluid-phase pinocytosis in quiescent fibroblasts by ras proteins
    • Bar-Sagi D., and Feramisco J.R. Induction of membrane ruffling and fluid-phase pinocytosis in quiescent fibroblasts by ras proteins. Science 233 (1986) 1061-1068
    • (1986) Science , vol.233 , pp. 1061-1068
    • Bar-Sagi, D.1    Feramisco, J.R.2
  • 3
    • 0035847021 scopus 로고    scopus 로고
    • Selective interaction of AGS3 with G-proteins and the influence of AGS3 on the activation state of G-proteins
    • Bernard M.L., Peterson Y.K., Chung P., Jourdan J., and Lanier S.M. Selective interaction of AGS3 with G-proteins and the influence of AGS3 on the activation state of G-proteins. J. Biol. Chem. 276 (2001) 1585-1593
    • (2001) J. Biol. Chem. , vol.276 , pp. 1585-1593
    • Bernard, M.L.1    Peterson, Y.K.2    Chung, P.3    Jourdan, J.4    Lanier, S.M.5
  • 4
    • 0035902180 scopus 로고    scopus 로고
    • Oncogenic kinase signalling
    • Blume-Jensen P., and Hunter T. Oncogenic kinase signalling. Nature 411 (2001) 355-365
    • (2001) Nature , vol.411 , pp. 355-365
    • Blume-Jensen, P.1    Hunter, T.2
  • 5
    • 0030987069 scopus 로고    scopus 로고
    • How receptors talk to trimeric G proteins
    • Bourne H.R. How receptors talk to trimeric G proteins. Curr. Opin. Cell Biol. 9 (1997) 134-142
    • (1997) Curr. Opin. Cell Biol. , vol.9 , pp. 134-142
    • Bourne, H.R.1
  • 6
    • 0025010979 scopus 로고
    • The GTPase superfamily: a conserved switch for diverse cell functions
    • Bourne H.R., Sanders D.A., and McCormick F. The GTPase superfamily: a conserved switch for diverse cell functions. Nature 348 (1990) 125-132
    • (1990) Nature , vol.348 , pp. 125-132
    • Bourne, H.R.1    Sanders, D.A.2    McCormick, F.3
  • 7
    • 3543114271 scopus 로고    scopus 로고
    • Foot and mouth: podosomes, invadopodia and circular dorsal ruffles
    • Buccione R., Orth J.D., and McNiven M.A. Foot and mouth: podosomes, invadopodia and circular dorsal ruffles. Nat. Rev. Mol. Cell Biol. 5 (2004) 647-657
    • (2004) Nat. Rev. Mol. Cell Biol. , vol.5 , pp. 647-657
    • Buccione, R.1    Orth, J.D.2    McNiven, M.A.3
  • 8
    • 15544373780 scopus 로고    scopus 로고
    • Structure of the p115RhoGEF rgRGS domain-Gα13/i1 chimera complex suggests convergent evolution of a GTPase activator
    • Chen Z., Singer W.D., Sternweis P.C., and Sprang S.R. Structure of the p115RhoGEF rgRGS domain-Gα13/i1 chimera complex suggests convergent evolution of a GTPase activator. Nat. Struct. Mol. Biol. 12 (2005) 191-197
    • (2005) Nat. Struct. Mol. Biol. , vol.12 , pp. 191-197
    • Chen, Z.1    Singer, W.D.2    Sternweis, P.C.3    Sprang, S.R.4
  • 10
    • 0034604518 scopus 로고    scopus 로고
    • Activation of heterotrimeric G-protein signaling by a ras-related protein. Implications for signal integration
    • Cismowski M.J., Ma C., Ribas C., Xie X., Spruyt M., Lizano J.S., Lanier S.M., and Duzic E. Activation of heterotrimeric G-protein signaling by a ras-related protein. Implications for signal integration. J. Biol. Chem. 275 (2000) 23421-23424
    • (2000) J. Biol. Chem. , vol.275 , pp. 23421-23424
    • Cismowski, M.J.1    Ma, C.2    Ribas, C.3    Xie, X.4    Spruyt, M.5    Lizano, J.S.6    Lanier, S.M.7    Duzic, E.8
  • 11
    • 0027245830 scopus 로고
    • Substitution of three amino acids switches receptor specificity of Gq α to that of Gi α
    • Conklin B.R., Farfel Z., Lustig K.D., Julius D., and Bourne H.R. Substitution of three amino acids switches receptor specificity of Gq α to that of Gi α. Nature 363 (1993) 274-276
    • (1993) Nature , vol.363 , pp. 274-276
    • Conklin, B.R.1    Farfel, Z.2    Lustig, K.D.3    Julius, D.4    Bourne, H.R.5
  • 12
    • 0035152391 scopus 로고    scopus 로고
    • Integrin-mediated adhesion regulates cell polarity and membrane protrusion through the Rho family of GTPases
    • Cox E.A., Sastry S.K., and Huttenlocher A. Integrin-mediated adhesion regulates cell polarity and membrane protrusion through the Rho family of GTPases. Mol. Biol. Cell 12 (2001) 265-277
    • (2001) Mol. Biol. Cell , vol.12 , pp. 265-277
    • Cox, E.A.1    Sastry, S.K.2    Huttenlocher, A.3
  • 13
    • 0030044360 scopus 로고    scopus 로고
    • Role of transactivation of the EGF receptor in signalling by G-protein-coupled receptors
    • Daub H., Weiss F.U., Wallasch C., and Ullrich A. Role of transactivation of the EGF receptor in signalling by G-protein-coupled receptors. Nature 379 (1996) 557-560
    • (1996) Nature , vol.379 , pp. 557-560
    • Daub, H.1    Weiss, F.U.2    Wallasch, C.3    Ullrich, A.4
  • 14
    • 0029929903 scopus 로고    scopus 로고
    • Differential distribution of α subunits and β γ subunits of heterotrimeric G proteins on Golgi membranes of the exocrine pancreas
    • Denker S.P., McCaffery J.M., Palade G.E., Insel P.A., and Farquhar M.G. Differential distribution of α subunits and β γ subunits of heterotrimeric G proteins on Golgi membranes of the exocrine pancreas. J. Cell Biol. 133 (1996) 1027-1040
    • (1996) J. Cell Biol. , vol.133 , pp. 1027-1040
    • Denker, S.P.1    McCaffery, J.M.2    Palade, G.E.3    Insel, P.A.4    Farquhar, M.G.5
  • 15
    • 0030772657 scopus 로고    scopus 로고
    • Localization of p21-activated kinase 1 (PAK1) to pinocytic vesicles and cortical actin structures in stimulated cells
    • Dharmawardhane S., Sanders L.C., Martin S.S., Daniels R.H., and Bokoch G.M. Localization of p21-activated kinase 1 (PAK1) to pinocytic vesicles and cortical actin structures in stimulated cells. J. Cell Biol. 138 (1997) 1265-1278
    • (1997) J. Cell Biol. , vol.138 , pp. 1265-1278
    • Dharmawardhane, S.1    Sanders, L.C.2    Martin, S.S.3    Daniels, R.H.4    Bokoch, G.M.5
  • 16
  • 17
    • 0029113832 scopus 로고
    • Transducin-α C-terminal mutations prevent activation by rhodopsin: a new assay using recombinant proteins expressed in cultured cells
    • Garcia P.D., Onrust R., Bell S.M., Sakmar T.P., and Bourne H.R. Transducin-α C-terminal mutations prevent activation by rhodopsin: a new assay using recombinant proteins expressed in cultured cells. EMBO J. 14 (1995) 4460-4469
    • (1995) EMBO J. , vol.14 , pp. 4460-4469
    • Garcia, P.D.1    Onrust, R.2    Bell, S.M.3    Sakmar, T.P.4    Bourne, H.R.5
  • 18
    • 0035854829 scopus 로고    scopus 로고
    • G α minigenes expressing C-terminal peptides serve as specific inhibitors of thrombin-mediated endothelial activation
    • Gilchrist A., Vanhauwe J.F., Li A., Thomas T.O., Voyno-Yasenetskaya T., and Hamm H.E. G α minigenes expressing C-terminal peptides serve as specific inhibitors of thrombin-mediated endothelial activation. J. Biol. Chem. 276 (2001) 25672-25679
    • (2001) J. Biol. Chem. , vol.276 , pp. 25672-25679
    • Gilchrist, A.1    Vanhauwe, J.F.2    Li, A.3    Thomas, T.O.4    Voyno-Yasenetskaya, T.5    Hamm, H.E.6
  • 19
    • 0023062991 scopus 로고
    • G proteins: transducers of receptor-generated signals
    • Gilman A.G. G proteins: transducers of receptor-generated signals. Annu. Rev. Biochem. 56 (1987) 615-649
    • (1987) Annu. Rev. Biochem. , vol.56 , pp. 615-649
    • Gilman, A.G.1
  • 20
    • 0033580697 scopus 로고    scopus 로고
    • Differential involvement of Gα12 and Gα13 in receptor-mediated stress fiber formation
    • Gohla A., Offermanns S., Wilkie T.M., and Schultz G. Differential involvement of Gα12 and Gα13 in receptor-mediated stress fiber formation. J. Biol. Chem. 274 (1999) 17901-17907
    • (1999) J. Biol. Chem. , vol.274 , pp. 17901-17907
    • Gohla, A.1    Offermanns, S.2    Wilkie, T.M.3    Schultz, G.4
  • 21
    • 0034745355 scopus 로고    scopus 로고
    • Distinct roles for Gα and Gβγ in regulating spindle position and orientation in Caenorhabditis elegans embryos
    • Gotta M., and Ahringer J. Distinct roles for Gα and Gβγ in regulating spindle position and orientation in Caenorhabditis elegans embryos. Nat. Cell Biol. 3 (2001) 297-300
    • (2001) Nat. Cell Biol. , vol.3 , pp. 297-300
    • Gotta, M.1    Ahringer, J.2
  • 23
    • 0032559362 scopus 로고    scopus 로고
    • Rho GTPases and the actin cytoskeleton
    • Hall A. Rho GTPases and the actin cytoskeleton. Science 279 (1998) 509-514
    • (1998) Science , vol.279 , pp. 509-514
    • Hall, A.1
  • 25
    • 0026083213 scopus 로고
    • The carboxyl terminus of Scg1, the G α subunit involved in yeast mating, is implicated in interactions with the pheromone receptors
    • Hirsch J.P., Dietzel C., and Kurjan J. The carboxyl terminus of Scg1, the G α subunit involved in yeast mating, is implicated in interactions with the pheromone receptors. Genes Dev. 5 (1991) 467-474
    • (1991) Genes Dev. , vol.5 , pp. 467-474
    • Hirsch, J.P.1    Dietzel, C.2    Kurjan, J.3
  • 27
    • 2942594298 scopus 로고    scopus 로고
    • Juxtamembrane autoinhibition in receptor tyrosine kinases
    • Hubbard S.R. Juxtamembrane autoinhibition in receptor tyrosine kinases. Nat. Rev. Mol. Cell Biol. 5 (2004) 464-471
    • (2004) Nat. Rev. Mol. Cell Biol. , vol.5 , pp. 464-471
    • Hubbard, S.R.1
  • 28
    • 0032558834 scopus 로고    scopus 로고
    • The G protein G α12 stimulates Bruton's tyrosine kinase and a rasGAP through a conserved PH/BM domain
    • Jiang Y., Ma W., Wan Y., Kozasa T., Hattori S., and Huang X.Y. The G protein G α12 stimulates Bruton's tyrosine kinase and a rasGAP through a conserved PH/BM domain. Nature 395 (1998) 808-813
    • (1998) Nature , vol.395 , pp. 808-813
    • Jiang, Y.1    Ma, W.2    Wan, Y.3    Kozasa, T.4    Hattori, S.5    Huang, X.Y.6
  • 29
    • 0033618396 scopus 로고    scopus 로고
    • Modulation of rap activity by direct interaction of Gα(o) with Rap1 GTPase-activating protein
    • Jordan J.D., Carey K.D., Stork P.J., and Iyengar R. Modulation of rap activity by direct interaction of Gα(o) with Rap1 GTPase-activating protein. J. Biol. Chem. 274 (1999) 21507-21510
    • (1999) J. Biol. Chem. , vol.274 , pp. 21507-21510
    • Jordan, J.D.1    Carey, K.D.2    Stork, P.J.3    Iyengar, R.4
  • 30
    • 0031002349 scopus 로고    scopus 로고
    • Analysis of the receptor binding domain of Gpa1p, the G(α) subunit involved in the yeast pheromone response pathway
    • Kallal L., and Kurjan J. Analysis of the receptor binding domain of Gpa1p, the G(α) subunit involved in the yeast pheromone response pathway. Mol. Cell. Biol. 17 (1997) 2897-2907
    • (1997) Mol. Cell. Biol. , vol.17 , pp. 2897-2907
    • Kallal, L.1    Kurjan, J.2
  • 31
    • 0037413823 scopus 로고    scopus 로고
    • Platelet-derived growth factor (PDGF)-induced chemotaxis does not require the G protein-coupled receptor S1P1 in murine embryonic fibroblasts and vascular smooth muscle cells
    • Kluk M.J., Colmont C., Wu M.T., and Hla T. Platelet-derived growth factor (PDGF)-induced chemotaxis does not require the G protein-coupled receptor S1P1 in murine embryonic fibroblasts and vascular smooth muscle cells. FEBS Lett. 533 (2003) 25-28
    • (2003) FEBS Lett. , vol.533 , pp. 25-28
    • Kluk, M.J.1    Colmont, C.2    Wu, M.T.3    Hla, T.4
  • 32
    • 0035955736 scopus 로고    scopus 로고
    • Human phosphatidylethanolamine-binding protein facilitates heterotrimeric G protein-dependent signaling
    • Kroslak T., Koch T., Kahl E., and Hollt V. Human phosphatidylethanolamine-binding protein facilitates heterotrimeric G protein-dependent signaling. J. Biol. Chem. 276 (2001) 39772-39778
    • (2001) J. Biol. Chem. , vol.276 , pp. 39772-39778
    • Kroslak, T.1    Koch, T.2    Kahl, E.3    Hollt, V.4
  • 33
    • 0037343053 scopus 로고    scopus 로고
    • A dynamin-cortactin-Arp2/3 complex mediates actin reorganization in growth factor-stimulated cells
    • Krueger E.W., Orth J.D., Cao H., and McNiven M.A. A dynamin-cortactin-Arp2/3 complex mediates actin reorganization in growth factor-stimulated cells. Mol. Biol. Cell 14 (2003) 1085-1096
    • (2003) Mol. Biol. Cell , vol.14 , pp. 1085-1096
    • Krueger, E.W.1    Orth, J.D.2    Cao, H.3    McNiven, M.A.4
  • 34
    • 2442650416 scopus 로고    scopus 로고
    • Rab5 is a signalling GTPase involved in actin remodelling by receptor tyrosine kinases
    • Lanzetti L., Palamidessi A., Areces L., Scita G., and Di Fiore P.P. Rab5 is a signalling GTPase involved in actin remodelling by receptor tyrosine kinases. Nature 429 (2004) 309-314
    • (2004) Nature , vol.429 , pp. 309-314
    • Lanzetti, L.1    Palamidessi, A.2    Areces, L.3    Scita, G.4    Di Fiore, P.P.5
  • 37
    • 0035895142 scopus 로고    scopus 로고
    • Interaction of Gα 12 and Gα 13 with the cytoplasmic domain of cadherin provides a mechanism for β-catenin release
    • Meigs T.E., Fields T.A., McKee D.D., and Casey P.J. Interaction of Gα 12 and Gα 13 with the cytoplasmic domain of cadherin provides a mechanism for β-catenin release. Proc. Natl. Acad. Sci. USA 98 (2001) 519-524
    • (2001) Proc. Natl. Acad. Sci. USA , vol.98 , pp. 519-524
    • Meigs, T.E.1    Fields, T.A.2    McKee, D.D.3    Casey, P.J.4
  • 38
    • 0033579209 scopus 로고    scopus 로고
    • Functional interaction between Gα(z) and Rap1GAP suggests a novel form of cellular cross-talk
    • Meng J., Glick J.L., Polakis P., and Casey P.J. Functional interaction between Gα(z) and Rap1GAP suggests a novel form of cellular cross-talk. J. Biol. Chem. 274 (1999) 36663-36669
    • (1999) J. Biol. Chem. , vol.274 , pp. 36663-36669
    • Meng, J.1    Glick, J.L.2    Polakis, P.3    Casey, P.J.4
  • 39
    • 0001793118 scopus 로고    scopus 로고
    • Identification and cDNA cloning of a novel human mosaic protein, LGN, based on interaction with G α i2
    • Mochizuki N., Cho G., Wen B., and Insel P.A. Identification and cDNA cloning of a novel human mosaic protein, LGN, based on interaction with G α i2. Gene 181 (1996) 39-43
    • (1996) Gene , vol.181 , pp. 39-43
    • Mochizuki, N.1    Cho, G.2    Wen, B.3    Insel, P.A.4
  • 41
    • 0030025047 scopus 로고    scopus 로고
    • Insulin action impaired by deficiency of the G-protein subunit G iα2
    • Moxham C.M., and Malbon C.C. Insulin action impaired by deficiency of the G-protein subunit G iα2. Nature 379 (1996) 840-844
    • (1996) Nature , vol.379 , pp. 840-844
    • Moxham, C.M.1    Malbon, C.C.2
  • 42
    • 0031015426 scopus 로고    scopus 로고
    • Vascular system defects and impaired cell chemokinesis as a result of Gα13 deficiency
    • Offermanns S., Mancino V., Revel J.P., and Simon M.I. Vascular system defects and impaired cell chemokinesis as a result of Gα13 deficiency. Science 275 (1997) 533-536
    • (1997) Science , vol.275 , pp. 533-536
    • Offermanns, S.1    Mancino, V.2    Revel, J.P.3    Simon, M.I.4
  • 43
  • 44
    • 0029569117 scopus 로고
    • The effect of carboxyl-terminal mutagenesis of Gt α on rhodopsin and guanine nucleotide binding
    • Osawa S., and Weiss E.R. The effect of carboxyl-terminal mutagenesis of Gt α on rhodopsin and guanine nucleotide binding. J. Biol. Chem. 270 (1995) 31052-31058
    • (1995) J. Biol. Chem. , vol.270 , pp. 31052-31058
    • Osawa, S.1    Weiss, E.R.2
  • 45
    • 0033599039 scopus 로고    scopus 로고
    • EGF receptor transactivation by G-protein-coupled receptors requires metalloproteinase cleavage of proHB-EGF
    • Prenzel N., Zwick E., Daub H., Leserer M., Abraham R., Wallasch C., and Ullrich A. EGF receptor transactivation by G-protein-coupled receptors requires metalloproteinase cleavage of proHB-EGF. Nature 402 (1999) 884-888
    • (1999) Nature , vol.402 , pp. 884-888
    • Prenzel, N.1    Zwick, E.2    Daub, H.3    Leserer, M.4    Abraham, R.5    Wallasch, C.6    Ullrich, A.7
  • 46
    • 10344234244 scopus 로고    scopus 로고
    • Gα13 stimulates cell migration through cortactin-interacting protein Hax-1
    • Radhika V., Onesime D., Ha J.H., and Dhanasekaran N. Gα13 stimulates cell migration through cortactin-interacting protein Hax-1. J. Biol. Chem. 279 (2004) 49406-49413
    • (2004) J. Biol. Chem. , vol.279 , pp. 49406-49413
    • Radhika, V.1    Onesime, D.2    Ha, J.H.3    Dhanasekaran, N.4
  • 47
    • 0026654125 scopus 로고
    • The small GTP-binding protein rac regulates growth factor-induced membrane ruffling
    • Ridley A.J., Paterson H.F., Johnston C.L., Diekmann D., and Hall A. The small GTP-binding protein rac regulates growth factor-induced membrane ruffling. Cell 70 (1992) 401-410
    • (1992) Cell , vol.70 , pp. 401-410
    • Ridley, A.J.1    Paterson, H.F.2    Johnston, C.L.3    Diekmann, D.4    Hall, A.5
  • 48
    • 0032828715 scopus 로고    scopus 로고
    • A generic protein purification method for protein complex characterization and proteome exploration
    • Rigaut G., Shevchenko A., Rutz B., Wilm M., Mann M., and Seraphin B. A generic protein purification method for protein complex characterization and proteome exploration. Nat. Biotechnol. 17 (1999) 1030-1032
    • (1999) Nat. Biotechnol. , vol.17 , pp. 1030-1032
    • Rigaut, G.1    Shevchenko, A.2    Rutz, B.3    Wilm, M.4    Mann, M.5    Seraphin, B.6
  • 49
    • 0030952289 scopus 로고    scopus 로고
    • Mechanisms of angiogenesis
    • Risau W. Mechanisms of angiogenesis. Nature 386 (1997) 671-674
    • (1997) Nature , vol.386 , pp. 671-674
    • Risau, W.1
  • 50
    • 0029860884 scopus 로고    scopus 로고
    • Characterization of a G-protein activator in the neuroblastoma-glioma cell hybrid NG108-15
    • Sato M., Ribas C., Hildebrandt J.D., and Lanier S.M. Characterization of a G-protein activator in the neuroblastoma-glioma cell hybrid NG108-15. J. Biol. Chem. 271 (1996) 30052-30060
    • (1996) J. Biol. Chem. , vol.271 , pp. 30052-30060
    • Sato, M.1    Ribas, C.2    Hildebrandt, J.D.3    Lanier, S.M.4
  • 51
    • 0035913905 scopus 로고    scopus 로고
    • Heterotrimeric G proteins direct two modes of asymmetric cell division in the Drosophila nervous system
    • Schaefer M., Petronczki M., Dorner D., Forte M., and Knoblich J.A. Heterotrimeric G proteins direct two modes of asymmetric cell division in the Drosophila nervous system. Cell 107 (2001) 183-194
    • (2001) Cell , vol.107 , pp. 183-194
    • Schaefer, M.1    Petronczki, M.2    Dorner, D.3    Forte, M.4    Knoblich, J.A.5
  • 53
    • 0025834532 scopus 로고
    • Diversity of G proteins in signal transduction
    • Simon M.I., Strathmann M.P., and Gautam N. Diversity of G proteins in signal transduction. Science 252 (1991) 802-808
    • (1991) Science , vol.252 , pp. 802-808
    • Simon, M.I.1    Strathmann, M.P.2    Gautam, N.3
  • 54
    • 2942678693 scopus 로고    scopus 로고
    • Bmx is a downstream Rap1 effector in VEGF-induced endothelial cell activation
    • Stoletov K.V., and Terman B.I. Bmx is a downstream Rap1 effector in VEGF-induced endothelial cell activation. Biochem. Biophys. Res. Commun. 320 (2004) 70-75
    • (2004) Biochem. Biophys. Res. Commun. , vol.320 , pp. 70-75
    • Stoletov, K.V.1    Terman, B.I.2
  • 55
    • 0141886295 scopus 로고    scopus 로고
    • Differential roles of WAVE1 and WAVE2 in dorsal and peripheral ruffle formation for fibroblast cell migration
    • Suetsugu S., Yamazaki D., Kurisu S., and Takenawa T. Differential roles of WAVE1 and WAVE2 in dorsal and peripheral ruffle formation for fibroblast cell migration. Dev. Cell 5 (2003) 595-609
    • (2003) Dev. Cell , vol.5 , pp. 595-609
    • Suetsugu, S.1    Yamazaki, D.2    Kurisu, S.3    Takenawa, T.4
  • 58
  • 60
    • 0037424298 scopus 로고    scopus 로고
    • Mammalian Ric-8A (synembryn) is a heterotrimeric Gα protein guanine nucleotide exchange factor
    • Tall G.G., Krumins A.M., and Gilman A.G. Mammalian Ric-8A (synembryn) is a heterotrimeric Gα protein guanine nucleotide exchange factor. J. Biol. Chem. 278 (2003) 8356-8362
    • (2003) J. Biol. Chem. , vol.278 , pp. 8356-8362
    • Tall, G.G.1    Krumins, A.M.2    Gilman, A.G.3
  • 63
    • 0042349229 scopus 로고    scopus 로고
    • ERK-MAPK signaling coordinately regulates activity of Rac1 and RhoA for tumor cell motility
    • Vial E., Sahai E., and Marshall C.J. ERK-MAPK signaling coordinately regulates activity of Rac1 and RhoA for tumor cell motility. Cancer Cell 4 (2003) 67-79
    • (2003) Cancer Cell , vol.4 , pp. 67-79
    • Vial, E.1    Sahai, E.2    Marshall, C.J.3
  • 64
    • 0037458681 scopus 로고    scopus 로고
    • Sphingosine 1-phosphate and platelet-derived growth factor (PDGF) act via PDGF β receptor-sphingosine 1-phosphate receptor complexes in airway smooth muscle cells
    • Waters C., Sambi B., Kong K.C., Thompson D., Pitson S.M., Pyne S., and Pyne N.J. Sphingosine 1-phosphate and platelet-derived growth factor (PDGF) act via PDGF β receptor-sphingosine 1-phosphate receptor complexes in airway smooth muscle cells. J. Biol. Chem. 278 (2003) 6282-6290
    • (2003) J. Biol. Chem. , vol.278 , pp. 6282-6290
    • Waters, C.1    Sambi, B.2    Kong, K.C.3    Thompson, D.4    Pitson, S.M.5    Pyne, S.6    Pyne, N.J.7
  • 65
    • 2342509663 scopus 로고    scopus 로고
    • The role of G-protein coupled receptors and associated proteins in receptor tyrosine kinase signal transduction
    • Waters C., Pyne S., and Pyne N.J. The role of G-protein coupled receptors and associated proteins in receptor tyrosine kinase signal transduction. Semin. Cell Dev. Biol. 15 (2004) 309-323
    • (2004) Semin. Cell Dev. Biol. , vol.15 , pp. 309-323
    • Waters, C.1    Pyne, S.2    Pyne, N.J.3
  • 66
    • 0031696485 scopus 로고    scopus 로고
    • Translocation of cortactin to the cell periphery is mediated by the small GTPase Rac1
    • Weed S.A., Du Y., and Parsons J.T. Translocation of cortactin to the cell periphery is mediated by the small GTPase Rac1. J. Cell Sci. 111 (1998) 2433-2443
    • (1998) J. Cell Sci. , vol.111 , pp. 2433-2443
    • Weed, S.A.1    Du, Y.2    Parsons, J.T.3
  • 67
    • 0028079674 scopus 로고
    • Cellular variations in heterotrimeric G protein localization and expression in rat pituitary
    • Wilson B.S., Komuro M., and Farquhar M.G. Cellular variations in heterotrimeric G protein localization and expression in rat pituitary. Endocrinology 134 (1994) 233-244
    • (1994) Endocrinology , vol.134 , pp. 233-244
    • Wilson, B.S.1    Komuro, M.2    Farquhar, M.G.3
  • 68
    • 0346037279 scopus 로고    scopus 로고
    • Evaluation of the catalytic mechanism of the p21-activated protein kinase PAK2
    • Wu H., Zheng Y., and Wang Z.X. Evaluation of the catalytic mechanism of the p21-activated protein kinase PAK2. Biochemistry 42 (2003) 1129-1139
    • (2003) Biochemistry , vol.42 , pp. 1129-1139
    • Wu, H.1    Zheng, Y.2    Wang, Z.X.3
  • 69
    • 0037031156 scopus 로고    scopus 로고
    • Gα(12) and Gα(13) interact with Ser/Thr protein phosphatase type 5 and stimulate its phosphatase activity
    • Yamaguchi Y., Katoh H., Mori K., and Negishi M. Gα(12) and Gα(13) interact with Ser/Thr protein phosphatase type 5 and stimulate its phosphatase activity. Curr. Biol. 12 (2002) 1353-1358
    • (2002) Curr. Biol. , vol.12 , pp. 1353-1358
    • Yamaguchi, Y.1    Katoh, H.2    Mori, K.3    Negishi, M.4
  • 70
    • 19744374764 scopus 로고    scopus 로고
    • Two G12 family G proteins, G α12 and G α13, show different subcellular localization
    • Yamazaki J., Katoh H., Yamaguchi Y., and Negishi M. Two G12 family G proteins, G α12 and G α13, show different subcellular localization. Biochem. Biophys. Res. Commun. 332 (2005) 782-786
    • (2005) Biochem. Biophys. Res. Commun. , vol.332 , pp. 782-786
    • Yamazaki, J.1    Katoh, H.2    Yamaguchi, Y.3    Negishi, M.4
  • 71
    • 22844433788 scopus 로고    scopus 로고
    • Ca2+ influx through L-type Ca2+ channels controls the trailing tail contraction in growth factor-induced fibroblast cell migration
    • Yang S., and Huang X.Y. Ca2+ influx through L-type Ca2+ channels controls the trailing tail contraction in growth factor-induced fibroblast cell migration. J. Biol. Chem. 280 (2005) 27130-27137
    • (2005) J. Biol. Chem. , vol.280 , pp. 27130-27137
    • Yang, S.1    Huang, X.Y.2
  • 72
    • 0034681261 scopus 로고    scopus 로고
    • Analysis of partner of inscuteable, a novel player of Drosophila asymmetric divisions, reveals two distinct steps in inscuteable apical localization
    • Yu F., Morin X., Cai Y., Yang X., and Chia W. Analysis of partner of inscuteable, a novel player of Drosophila asymmetric divisions, reveals two distinct steps in inscuteable apical localization. Cell 100 (2000) 399-409
    • (2000) Cell , vol.100 , pp. 399-409
    • Yu, F.1    Morin, X.2    Cai, Y.3    Yang, X.4    Chia, W.5


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