A dynamin-cortactin-Arp2/3 complex mediates actin reorganization in growth factor-stimulated cells

Molecular Biology of the Cell

Volumn 14, Issue 3, 2003, Pages 1085-1096

  Krueger, Eugene W ^a   Orth, James D ^a   Cao, Hong ^a   McNiven, Mark A ^a  

^a MAYO CLINIC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIN; ACTIN BINDING PROTEIN; CORTACTIN; DYNAMIN; GROWTH FACTOR; PLATELET DERIVED GROWTH FACTOR;

ACTIN FILAMENT; ANIMAL CELL; ARTICLE; CARBOXY TERMINAL SEQUENCE; CELL MIGRATION; CELL STIMULATION; CIRCULAR DICHROISM; COMPLEX FORMATION; GENE REARRANGEMENT; GENETIC ORGANIZATION; LAMELLIPODIUM; MAMMAL CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTEIN FAMILY; PROTEIN PROTEIN INTERACTION;

ACTIN-RELATED PROTEIN 3; ACTINS; ANIMALS; CELL LINE; CELL MOVEMENT; CELL SURFACE EXTENSIONS; CORTACTIN; CYTOSKELETAL PROTEINS; CYTOSKELETON; DYNAMINS; HUMANS; MACROMOLECULAR SUBSTANCES; MICE; MICROFILAMENT PROTEINS; PLATELET-DERIVED GROWTH FACTOR; RECOMBINANT FUSION PROTEINS;

ANIMALIA; MAMMALIA;

EID: 0037343053     PISSN: 10591524     EISSN: None     Source Type: Journal    
DOI: 10.1091/mbc.E02-08-0466     Document Type: Article

References (42)

1. Baldassarre, M., Pompeo, A., Castaldi, C., Cortelino, S., Beznoussenko, G., McNiven, M.A., Luini, A., and Buccione, R. (2003). Dynamin participates in focal extracellular matrix degradation by invasive cells. Mol. Biol. Cell 13, 1074-1084.
2. Bowden, E.T., Barth, M., Thomas, D., Glazer, R.I., and Mueller, S.C. (1999). An invasion-related complex of cortactin, paxillin and PKCm associates with invadopodia at sites of extracellular matrix degradation. Oncogene 18, 4440-4449.
3. Cao, H., Garcia, F., and McNiven, M. (1998). Differential distribution of dynamin isoforms in mammalian cells. Mol. Biol. Cell 9, 2595-2609.
4. DeFife, K.M., Jenney, C.R., Colton, E., and Anderson, J.M. (1999). Cytoskeletal and adhesive structural polarizations accompany IL- 13-induced human macrophage fusion. J. Histol. Cytol. 47, 65-74.
5. Heldin, C.H., Ostman, A., and Ronnstrand, L. (1998). Signal transduction via platelet-derived growth factor receptors. Biochem. Biophys. Acta 1378, F79-F113.
6. Henley, J.R., Krueger, E.W., Oswald, B.J., and McNiven, M.A. (1998). Dynamin-mediated internalization of caveolae. J. Cell Biol. 141, 85-99.
7. Hinshaw, J.E. (2000). Dynamin and its role in membrane fission. Annu. Rev. Cell Dev. Biol. 16, 483-519.
8. Huang, C., Yansong, N., Wang, T., Gao, Y., Haudenschild, C.C., and Zhan, X. (1997). Down-regulation of the filamentous actin cross-linking activity of cortactin by Src-mediated tyrosine phosphorylation. J. Biol. Chem. 272, 13911-13915.
9. Jackson, T.R., Brown, F.D., Nie, Z., Miura, K., Foroni, L., Sun, J., Hsu, V.W., Donaldson, J.G., and Randazzo, P.A. (2000). ACAPs are Arf6 GTPase-activating proteins that function in the cell periphery. J. Cell Biol. 151, 627-638.
10. Kao, A.W., Ceresa, B.P., Santeler, S.R., and Pessin, J.E. (1998). Expression of a dominant interfering dynamin mutant in 3T3L1 adipocytes inhibits GLUT4 endocytosis without affecting insulin signaling. J. Biol. Chem. 273, 25450-25457.
11. Lee, E., and De Camilli, P. (2002). Dynamin at actin tails. Proc. Natl. Acad. Sci. USA 99, 161-166.
12. Linder, S., Nelson, D., Weiss, M., and Aepfelbacher, M. (1999). Wiskott-Aldrich syndrome protein regulates podosomes in primary human macrophages. Proc. Natl. Acad. Sci. USA 96, 9648-9653.
13. McNiven, M.A., Cao, H., Pitts, K.R., and Yoon, Y. (2000a). Pinching in new places: multiple functions for the dynamin family. Trends Biochem. Sci. 25, 115-120.
14. McNiven, M.A., Kim, L., Krueger, E.W., Orth, J.D., Cao, H., and Wong, T.W. (2000b). Interactions between dynamin and the actin binding protein cortactin modulate cell shape. J. Cell Biol. 151, 187-198.
15. Mellstrom, K., Heldin, C.H., and Westermark, B. (1988). Induction of circular membrane ruffling on human fibroblasts by platelet-derived growth factor. Exp. Cell Res. 177, 347-359.
16. Mellstrom, K., Hoglund, A.S., Nister, M., Heldin, C.H., Westermark, B., and Lindberg, U. (1983). The effect of platelet-derived growth factor on morphology and motility of human glial cells. J. Muscle Res. Cell Motil. 4, 589-609.
17. Miki, H., Miura, K., and Takenawa, T. (1996). N-WASP, a novel actin-depolymerizing protein, regulates the cortical cytoskeletal rearrangement in a PIP2-dependent manner downstream of tyrosine kinases. EMBO J. 15, 5326-5335.
18. Mullins, R.D. (2000). How WASP-family proteins, and the Arp2/3 complex convert intracellular signals into cytoskeletal structures. Curr. Opin. Cell Biol. 12, 91-96.
19. Nitsch, L., Gionti, E., Cancedda, R., and Marchisio, P.C. (1989). The podosomes of Rous sarcoma virus transformed chondrocytes show a peculiar ultrastructural organization. Cell Biol. Int. Rep. 13, 919-926.
20. Nobes, C.D., and Hall, A. (1995). Rho, Rac, and Cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia, and filopodia. Cell 81, 53-62.
21. Ochoa, G.-C., Slepnev, V.I., Neff, L., Ringstad, N., Takei, K., Daniell, L., Cao, H., McNiven, M., Baron, R., and De Camilli, P. (2000). A functional link between dynamin and the actin cytoskeleton at podosome. J. Cell Biol. 150, 377-389.
22. Olazabal, I.M., and Machesky, L.M. (2001). Abp1p and cortactin, new "hand-holds" for actin. J. Cell Biol. 154, 679-682.
23. Orth, J.D., Krueger, E.W., Cao, H., and McNiven, M.A. (2002). The large GTPase dynamin regulates actin comet formation and movement in living cells. Proc. Natl. Acad. Sci. USA 99, 167-172.
24. Parsons, J.T., and Parsons, S.J. (1997). Src family protein tyrosine kinases: cooperating with growth factor and adhesion signaling pathways. Curr. Opin. Cell Biol. 9, 187-192.
25. Randazzo, P.A., Andrade, J., Miura, K., Brown, M.T., Long, Y.Q., Stauffer, S., Roller, P., and Cooper, J.A. (2000). The Arf GTPase-activating protein ASAP1 regulates the actin cytoskeleton. Proc. Natl. Acad. Sci. USA 97, 4011-4016.
26. Ridley, A.J., and Hall, A. (1992). The small GTP-binding protein rho regulates the assembly of focal adhesions and stress fibers in response to growth factors. Cell. 70, 389-399.
27. Ridley, A.J., Peterson, H.F., Johnston, C.L., Diekmann, D., and Hall, A. (1992). The small GTP-binding protein rac regulates growth factor-induced membrane ruffling. Cell 70, 401-410.
28. Ruthel, G., and Banker, G. (1998). Actin-dependent anterograde movement of growth-cone-like structures along growing hippocampal axons: a novel form of axonal transport? Cell Motil. Cytoskeleton 40, 160-173.
29. Ruthel, G., and Banker, G. (1999). Role of moving growth cone-like "wave" structures in the outgrowth of cultured hippocampal axons and dendrites. J. Neurobiol. 39, 97-106.
30. Schafer, D.A., Weed, S.A., Binns, D., Karginov, A.V., Parsons, J.T., and Cooper, J.A. (2002). Dynamin 2 and cortactin regulate actin assembly and filament organization. Curr. Biol. 12, 1852-1857.
31. Schliwa, M., Nakamura, T., Porter, K.R., and Euteneuer, U. (1984). A tumor promoter induces rapid and coordinated reorganization of actin and vinculin in cultured cells. J. Cell Biol. 99, 1045-1059.
32. Soriano, P., Montgomery, C., Geske, R., and Bradley, A. (1991). Targeted disruption of the c-src proto-oncogene leads to osteopetrosis in mice. Cell 64, 693-702.
33. Sweitzer, S.M., and Hinshaw, J.E. (1998). Dynamin undergoes a GTP-dependent conformational change causing vesiculation. Cell 93, 1021-1029.
34. Tanaka, S., Amling, M., Neff, L., Peyman, A., Uhlmann, E., Levy, J.B., and Baron, R. (1996). c-Cbl is downstream of c-Src in a signaling pathway necessary for bone resorption. Nature 383, 528-531.
35. Tarone, G., Cirillo, D., Giancotti, F.G., Comoglio, P.M., and Marchisio, P.C. (1985). Rous sarcoma virus-transformed fibroblasts adhere primarily at discrete protrusions of the ventral membrane called podosomes. Exp. Cell Res. 159, 141-157.
36. Vieira, A.V., Lamaze, C., and Schmid, S.L. (1996). Control of EGF receptor signaling by clathrin-mediated endocytosis. Science 274, 2086-2089.
37. Weed, S., Du, Y., and Parsons, J. (1998). Translocation of cortactin to the cell periphery is mediated by the small GTPase Rac1. J. Cell Sci. 111, 2433-2443.
38. Weed, S.A., Karginov, A.V., Schafer, D.A., Weaver, A.M., Kinley, A.W., Cooper, J.A., and Parsons, J.T. (2000). Cortactin localization to sites of actin assembly in lamellipodia requires interactions with F-actin and the Arp2/3 complex. J. Cell Biol. 151, 29-40.
39. Welch, M.D. (1999). The world according to Arp: regulation of actin nucleation by the Arp2/3 complex. Trends Cell Biol. 9, 423-427.
40. Westphal, R.S., Soderling, S.H., Alto, N.M., Langeberg, L.K., and Scott, J.D. (2000). Scar/WAVE-1, a Wiskott-Aldrich syndrome protein, assembles an actin-associated multi-kinase scaffold. EMBO J. 19, 4589-4600.
41. src substrate, is a filamentous actin-binding protein enriched in the cell cortex. J. Cell Biol. 120, 1417-1426.
42. src substrate. Mol. Cell. Biol. 11, 5113-5124.