-
1
-
-
0001049464
-
Obtaining value from the human genome: A challenge for the pharmaceutical industry
-
Spence, P. Obtaining value from the human genome: a challenge for the pharmaceutical industry. Drug Disc. Today 3, 179-188 (1998).
-
(1998)
Drug Disc. Today
, vol.3
, pp. 179-188
-
-
Spence, P.1
-
2
-
-
0028116553
-
Cloning by function: Expression cloning in mammalian cells
-
Simonsen, H. & Lodish, H.F. Cloning by function: expression cloning in mammalian cells. Trends Pharmacol. Sci. 15, 437-441 (1994).
-
(1994)
Trends Pharmacol. Sci.
, vol.15
, pp. 437-441
-
-
Simonsen, H.1
Lodish, H.F.2
-
3
-
-
0030964025
-
Gene trapping and functional genomics
-
Evans, M.J., Carlton, M.B. & Russ, A.P. Gene trapping and functional genomics. Trends Genet. 13, 370-374 (1997).
-
(1997)
Trends Genet.
, vol.13
, pp. 370-374
-
-
Evans, M.J.1
Carlton, M.B.2
Russ, A.P.3
-
4
-
-
0030879562
-
Functional genomics in mice by tagged sequence mutagenesis
-
Hicks, G.G. et al. Functional genomics in mice by tagged sequence mutagenesis. Nat. Genet. 16, 338-344 (1997).
-
(1997)
Nat. Genet.
, vol.16
, pp. 338-344
-
-
Hicks, G.G.1
-
5
-
-
0031733589
-
A genome-wide functional assay of signal transduction in living mammalian cells
-
Whitney, M. et al. A genome-wide functional assay of signal transduction in living mammalian cells. Nar. Biotechnol. 16, 1329-1333 (1998).
-
(1998)
Nar. Biotechnol.
, vol.16
, pp. 1329-1333
-
-
Whitney, M.1
-
6
-
-
0029074950
-
Human RNA polymerase II subunit hsRPB7 functions in yeast and influences stress survival and cell morphology
-
Khazak, V., Sadhale, P.P., Woychik, N.A., Brent, R. & Golemis, E.A. Human RNA polymerase II subunit hsRPB7 functions in yeast and influences stress survival and cell morphology. Mol. Cell. Biol. 6, 759-775 (1995).
-
(1995)
Mol. Cell. Biol.
, vol.6
, pp. 759-775
-
-
Khazak, V.1
Sadhale, P.P.2
Woychik, N.A.3
Brent, R.4
Golemis, E.A.5
-
7
-
-
0029891787
-
Human enhancer of filamentation 1, a novel p130cas-like docking protein, associates with focal adhesion kinase and induces pseudohyphal growth in Saccharomyces cerevisiae
-
Law, S.F. et al. Human enhancer of filamentation 1, a novel p130cas-like docking protein, associates with focal adhesion kinase and induces pseudohyphal growth in Saccharomyces cerevisiae. Mol. Cell. Biol. 16, 3327-3337 (1996).
-
(1996)
Mol. Cell. Biol.
, vol.16
, pp. 3327-3337
-
-
Law, S.F.1
-
8
-
-
0027144459
-
The pheromone response pathway in Saccharomyces cerevisiae
-
Kurjan, J. The pheromone response pathway in Saccharomyces cerevisiae. Annu. Rev. Genet. 27, 147-179 (1993).
-
(1993)
Annu. Rev. Genet.
, vol.27
, pp. 147-179
-
-
Kurjan, J.1
-
9
-
-
0028556727
-
Signal propagation and regulation in the mating pheromone response pathway of the yeast Saccharomyces cerevisiae
-
Bardwell, L., Cook, J.G., Inouye, C.J. & Thorner, J. Signal propagation and regulation in the mating pheromone response pathway of the yeast Saccharomyces cerevisiae. Dev. Biol. 166, 363-379 (1994).
-
(1994)
Dev. Biol.
, vol.166
, pp. 363-379
-
-
Bardwell, L.1
Cook, J.G.2
Inouye, C.J.3
Thorner, J.4
-
10
-
-
0025605219
-
Identification of a gene necessary for cell cycle arrest by a negative growth factor of yeast: FAR1 is an inhibitor of a G1 cyclin, CLN2
-
Chang, F. & Herskowitz, I. Identification of a gene necessary for cell cycle arrest by a negative growth factor of yeast: FAR1 is an inhibitor of a G1 cyclin, CLN2. Cell 63, 999-1011 (1990).
-
(1990)
Cell
, vol.63
, pp. 999-1011
-
-
Chang, F.1
Herskowitz, I.2
-
11
-
-
0028085427
-
Direct inhibition of the yeast cyclin-dependent kinase Cdc28-Cln by Far1
-
Peter, M. & Herskowitz, I. Direct inhibition of the yeast cyclin-dependent kinase Cdc28-Cln by Far1. Science 265, 1228-1231 (1994).
-
(1994)
Science
, vol.265
, pp. 1228-1231
-
-
Peter, M.1
Herskowitz, I.2
-
13
-
-
0026774153
-
Constitutive mutants of the protein kinase STE11 activate the yeast pheromone response pathway in the absence of the G protein
-
Stevenson, B.J., Rhodes, N., Errede, B. & Sprague, G.F. Constitutive mutants of the protein kinase STE11 activate the yeast pheromone response pathway in the absence of the G protein. Genes Dev. 6, 1293-1304 (1992).
-
(1992)
Genes Dev.
, vol.6
, pp. 1293-1304
-
-
Stevenson, B.J.1
Rhodes, N.2
Errede, B.3
Sprague, G.F.4
-
14
-
-
0028840683
-
Functional coupling of a mammalian somatostatin receptor to the yeast pheromone response pathway
-
Price, L.A., Kajkowski, E.M., Hadcock, J.R., Ozenberger, B.A. & Pausch, M.H. Functional coupling of a mammalian somatostatin receptor to the yeast pheromone response pathway. Mol. Cell. Biol. 15, 6188-6195 (1995).
-
(1995)
Mol. Cell. Biol.
, vol.15
, pp. 6188-6195
-
-
Price, L.A.1
Kajkowski, E.M.2
Hadcock, J.R.3
Ozenberger, B.A.4
Pausch, M.H.5
-
15
-
-
0029762164
-
Yeast a mating factor structure-activity relationship derived from genetically selected peptide agonists and antagonists of Ste2p
-
Manfredi, J.P. et al. Yeast a mating factor structure-activity relationship derived from genetically selected peptide agonists and antagonists of Ste2p. Mol. Cell. Biol. 16, 4700-4709 (1996).
-
(1996)
Mol. Cell. Biol.
, vol.16
, pp. 4700-4709
-
-
Manfredi, J.P.1
-
16
-
-
0028867027
-
Mutation of RGA1, which encodes a putative GTPase-activating protein for the polarity-establishment protein Cdc42p, activates the pheromone-response pathway in the yeast Saccharomyces cerevisiae
-
Stevenson, B.J. et al. Mutation of RGA1, which encodes a putative GTPase-activating protein for the polarity-establishment protein Cdc42p, activates the pheromone-response pathway in the yeast Saccharomyces cerevisiae. Genes Dev. 9, 2949-2963 (1995).
-
(1995)
Genes Dev.
, vol.9
, pp. 2949-2963
-
-
Stevenson, B.J.1
-
17
-
-
18744426569
-
Identification of surrogate agonists for the human FPRL-1 receptor by autocrine selection in yeast
-
Klein, C. et al. Identification of surrogate agonists for the human FPRL-1 receptor by autocrine selection in yeast. Nat. Biotechnol. 16, 1334-1337 (1998).
-
(1998)
Nat. Biotechnol.
, vol.16
, pp. 1334-1337
-
-
Klein, C.1
-
19
-
-
0029860884
-
Characterization of a G protein activator in the neuroblastoma glioma cell hybrid NG108-15
-
Sato, M., Ribas, C., Hildebrandt, J.D. & Lanier, S.M. Characterization of a G protein activator in the neuroblastoma glioma cell hybrid NG108-15. J. Biol. Chem. 271, 30052-30060 (1996).
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 30052-30060
-
-
Sato, M.1
Ribas, C.2
Hildebrandt, J.D.3
Lanier, S.M.4
-
20
-
-
0026020420
-
Vectors for expression of cloned genes in yeast: Regulation, overproduction, and underproduction
-
Schneider, J.C. & Guarente, L. Vectors for expression of cloned genes in yeast: regulation, overproduction, and underproduction. Methods Enzymol. 194, 373-388 (1991).
-
(1991)
Methods Enzymol.
, vol.194
, pp. 373-388
-
-
Schneider, J.C.1
Guarente, L.2
-
21
-
-
0032488810
-
Dexamethasone rapidly induces a novel Ras superfamily member-related gene in AtT-20 cells
-
Kemppainen, R.J. & Behrend, E.N. Dexamethasone rapidly induces a novel Ras superfamily member-related gene in AtT-20 cells. J. Biol. Chem. 273, 3129-3131 (1998).
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 3129-3131
-
-
Kemppainen, R.J.1
Behrend, E.N.2
-
22
-
-
0026610270
-
sα highlights the requirement for dissociation of G protein subunits
-
sα highlights the requirement for dissociation of G protein subunits. J. Biol. Chem. 267, 1212-1218 (1992).
-
(1992)
J. Biol. Chem.
, vol.267
, pp. 1212-1218
-
-
Lee, E.1
Taussig, R.2
Gilman, A.G.3
-
23
-
-
0030576518
-
GAIP and RGS4 are GTPase activating proteins for the Gi subfamily of G protein o subunits
-
Berman, D.M., Wilkie, T.M. & Gilman, A.G. GAIP and RGS4 are GTPase activating proteins for the Gi subfamily of G protein o subunits. Cell 86, 445-452 (1996).
-
(1996)
Cell
, vol.86
, pp. 445-452
-
-
Berman, D.M.1
Wilkie, T.M.2
Gilman, A.G.3
-
24
-
-
0025908897
-
The ras protein family: Evolutionary tree and role of conserved amino acids
-
Valencia, A., Chardin, P., Wittinghofer, A. & Sander, C. The ras protein family: evolutionary tree and role of conserved amino acids. Biochemistry 30, 4637-4648 (1991).
-
(1991)
Biochemistry
, vol.30
, pp. 4637-4648
-
-
Valencia, A.1
Chardin, P.2
Wittinghofer, A.3
Sander, C.4
-
25
-
-
0026090063
-
In vitro mutagenesis and plasmid shuffling: From cloned gene to mutant yeast
-
Sikorski, R.S. & Boeke, J.D. In vitro mutagenesis and plasmid shuffling: from cloned gene to mutant yeast. Methods Enzymol. 194, 302-318 (1991).
-
(1991)
Methods Enzymol.
, vol.194
, pp. 302-318
-
-
Sikorski, R.S.1
Boeke, J.D.2
-
26
-
-
0026030413
-
Vectors for constitutive and inducible gene expression in yeast
-
Schena, M., Picard, D. & Yamamoto, K.R. Vectors for constitutive and inducible gene expression in yeast. Methods Enzymol. 194, 389-398 (1991).
-
(1991)
Methods Enzymol.
, vol.194
, pp. 389-398
-
-
Schena, M.1
Picard, D.2
Yamamoto, K.R.3
-
27
-
-
0030933718
-
Characterization of a novel mammalian RGS protein that binds to G alpha proteins and inhibits pheromone signaling in yeast
-
Chen, C., Zheng, B., Han, J. & Lin, S.C. Characterization of a novel mammalian RGS protein that binds to G alpha proteins and inhibits pheromone signaling in yeast. J. Biol. Chem. 272, 8679-8685 (1997).
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 8679-8685
-
-
Chen, C.1
Zheng, B.2
Han, J.3
Lin, S.C.4
-
28
-
-
0004136246
-
-
Cold Spring Harbor Laboratory Press, New York
-
Sambrook, J., Fritsch, E.F. & Maniatis, T. in Molecular cloning: a laboratory manual, 2nd edn (Cold Spring Harbor Laboratory Press, New York; 1989).
-
(1989)
Molecular Cloning: a Laboratory Manual, 2nd Edn
-
-
Sambrook, J.1
Fritsch, E.F.2
Maniatis, T.3
-
29
-
-
0020529962
-
Transformation of intact yeast cells treated with alkali cations
-
Ito, H., Fukuda, Y., Murata, K. & Kimora, A. Transformation of intact yeast cells treated with alkali cations. J. Bacteriol. 153, 163-168 (1983).
-
(1983)
J. Bacteriol.
, vol.153
, pp. 163-168
-
-
Ito, H.1
Fukuda, Y.2
Murata, K.3
Kimora, A.4
-
30
-
-
0028125792
-
Nucleotide sequence of the yeast STE14 gene, which encodes farnesylcysteine carboxylmethyltransferase, and demonstration of its essential role in a-factor export
-
Sapperstein, S., Berkower, C. & Michaelis, S. Nucleotide sequence of the yeast STE14 gene, which encodes farnesylcysteine carboxylmethyltransferase, and demonstration of its essential role in a-factor export. Mol. Cell. Biol. 14, 1438-1449 (1994).
-
(1994)
Mol. Cell. Biol.
, vol.14
, pp. 1438-1449
-
-
Sapperstein, S.1
Berkower, C.2
Michaelis, S.3
-
31
-
-
0025979877
-
Targeting, disruption, replacement, and allele rescue: Integrative DNA transformation in yeast
-
Rothstein, R. Targeting, disruption, replacement, and allele rescue: integrative DNA transformation in yeast. Methods Enzymol. 194, 281-302 (1991).
-
(1991)
Methods Enzymol.
, vol.194
, pp. 281-302
-
-
Rothstein, R.1
-
32
-
-
0023484186
-
5-Fluoroorotic acid as a selective agent in yeast molecular genetics
-
Boeke, J.D., Trueheart, J., Natsoulis, G. & Fink, G.R. 5-Fluoroorotic acid as a selective agent in yeast molecular genetics. Methods Enzymol. 154, 164-195 (1987).
-
(1987)
Methods Enzymol.
, vol.154
, pp. 164-195
-
-
Boeke, J.D.1
Trueheart, J.2
Natsoulis, G.3
Fink, G.R.4
-
33
-
-
0023664976
-
The yeast SCG1 gene: A Gα-like protein implicated in the a-and α-factor response pathway
-
Dietzel, C. & Kurjan, J. The yeast SCG1 gene: a Gα-like protein implicated in the a-and α-factor response pathway. Cell 50, 1001-1010 (1987).
-
(1987)
Cell
, vol.50
, pp. 1001-1010
-
-
Dietzel, C.1
Kurjan, J.2
-
34
-
-
0024669291
-
A system of shuttle vectors and yeast host strains designed for efficient manipulation of DNA in Saccharomyces cerevisiae
-
Sikorski, R.S. & Hieter, P. A system of shuttle vectors and yeast host strains designed for efficient manipulation of DNA in Saccharomyces cerevisiae. Genetics 122, 19-27 (1989).
-
(1989)
Genetics
, vol.122
, pp. 19-27
-
-
Sikorski, R.S.1
Hieter, P.2
-
36
-
-
0009602837
-
-
(ed. Inouye, M.) Academic Press, New York
-
Broach, J.R., Li, Y.Y., Wu, L.C.C. & Jayarum, M. in Experimental manipulation of gene expression (ed. Inouye, M.) (Academic Press, New York; 1983).
-
(1983)
Experimental Manipulation of Gene Expression
-
-
Broach, J.R.1
Li, Y.Y.2
Wu, L.C.C.3
Jayarum, M.4
-
37
-
-
0025963058
-
Recovery of plasmids from yeast into Escherichia coli: Shuttle vectors
-
Strathern, J.N. & Higgins, D.R. Recovery of plasmids from yeast into Escherichia coli: shuttle vectors. Methods Enzymol. 194, 319-329 (1991).
-
(1991)
Methods Enzymol.
, vol.194
, pp. 319-329
-
-
Strathern, J.N.1
Higgins, D.R.2
-
38
-
-
0027336046
-
CDC28 higtone H1 kinase activity is unable to promote entry into mitosis in checkpoint-arrested cells of the yeast Saccharomyces cerevisiae
-
CDC28 higtone H1 kinase activity is unable to promote entry into mitosis in checkpoint-arrested cells of the yeast Saccharomyces cerevisiae. Mol. Cell. Biol. 13, 3744-3755 (1993).
-
(1993)
Mol. Cell. Biol.
, vol.13
, pp. 3744-3755
-
-
Stueland, C.S.1
Lew, D.J.2
Cismowski, M.J.3
Reed, S.I.4
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