Microwave-assisted solution phase synthesis of dihydropyrimidine C5 amides and esters

Tetrahedron

Volumn 62, Issue 19, 2006, Pages 4651-4664

  Desai, Bimbisar ^a   Dallinger, Doris ^a   Kappe, C Oliver ^a  

^a UNIVERSITY OF GRAZ   (Austria)

Author keywords

Amide couplings; Continuous flow techniques; Fluorous synthesis; Microwave synthesis; Mitsunobu reaction; Pyrimidines

Indexed keywords

1,2,3,4 TETRAHYDRO 1,6 DIMETHYL 2 OXOPHENYLPYRIMIDINE 5 CARBOXYLIC ACID; 1,2,3,4 TETRAHYDRO 1,6 DIMETHYL 4 (3 NITROPHENYL) 2 OXOPYRIMIDINE 5 CARBOXYLIC ACID; 1,2,3,4 TETRAHYDRO 6 METHYL 2 OXOPHENYLPYRIMIDINE 5 CARBOXYLIC ACID; 3 FLUOROBENZYL 6 METHYL 4 PHENYL 2 OXO 1,2,3,4 TETRAHYDROPYRIMIDINE 5 CARBOXYLATE; ALLYL 1,6 DIMETHYL 4 (3 NITROPHENYL) 2 OXO 1,2,3,4 TETRAHYDROPYRIMIDINE 5 CARBOXYLATE; ALLYL 6 METHYL 4 (2 CHLOROPHENYL) 2 THIOXO 1,2,3,4 TETRAHYDROPYRIMIDINE 5 CARBOXYLATE; ALLYL 6 METHYL 4 (3 NITROPHENYL) 2 THIOXO 1,2,3,4 TETRAHYDROPYRIMIDINE 5 CARBOXYLATE; ALLYL 6 METHYL 4 (4 BROMOPHENYL) 2 OXO 1,2,3,4 TETRAHYDROPYRIMIDINE 5 CARBOXYLATE; ALLYL 6 METHYL 4 (4 CHLOROPHENYL) 2 OXO 1,2,3,4 TETRAHYDROPYRIMIDINE 5 CARBOXYLATE; ALLYL 6 METHYL 4 PHENYL 2 THIOXO 1,2,3,4 TETRAHYDROPYRIMIDINE 5 CARBOXYLATE; ALLYL 6 METHYL 4 TOLYL 2 THIOXO 1,2,3,4 TETRAHYDROPYRIMIDINE 5 CARBOXYLATE; BENZYL 1,6 DIMETHYL 4 PHENYL 2 OXO 1,2,3,4 TETRAHYDROPYRIMIDINE 5 CARBOXYLATE; BENZYL 4,6 DIPHENYL 2 OXO 1,2,3,4 TETRAHYDROPYRIMIDINE 5 CARBOXYLATE; BENZYL 6 METHYL 4 PHENYL 2 OXO 1,2,3,4 TETRAHYDROPYRIMIDINE 5 CARBOXYLATE; BENZYL 6 METHYL 4 TOLYL 2 OXO 1,2,3,4 TETRAHYDROPYRIMIDINE 5 CARBOXYLATE; BUTYL 6 METHYL 4 PHENYL 2 OXO 1,2,3,4 TETRAHYDROPYRIMIDINE 5 CARBOXYLATE; N BENZYL 1,2,3,4 TETRAHYDRO 1,6 DIMETHYL 2 OXO 4 (3 NITROPHENYL)PYRIMIDINE 5 CARBOXAMIDE; N BENZYL 1,2,3,4 TETRAHYDRO 2 OXO 4,6 DIPHENYLPYRIMIDINE 5 CARBOXAMIDE; N BENZYL 1,2,3,4 TETRAHYDRO 6 METHYL 2 OXO 4 (4 TOLYL)PYRIMIDINE 5 CARBOXAMIDE; N BENZYL 1,2,3,4 TETRAHYDRO 6 METHYL 2 OXO 4 PHENYLPYRIMIDINE 5 CARBOXAMIDE; N BENZYL 1,2,3,4 TETRAHYDRO 6 METHYL 2 THIOXO 4 (2 CHLOROPHENYL)PYRIMIDINE 5 CARBOXAMIDE; N BENZYL 1,2,3,4 TETRAHYDRO 6 METHYL 2 THIOXO 4 (4 TOLYL)PYRIMIDINE 5 CARBOXAMIDE; N PROPYL 1,2,3,4 TETRAHYDRO 1,6 DIMETHYL 2 OXO 4 PHENYLPYRIMIDINE 5 CARBOXAMIDE; N PROPYL 1,2,3,4 TETRAHYDRO 6 METHYL 2 OXO 4 (4 BROMOPHENYL)PYRIMIDINE 5 CARBOXAMIDE; N PROPYL 1,2,3,4 TETRAHYDRO 6 METHYL 2 THIOXO 4 (3 NITROPHENYL)PYRIMIDINE 5 CARBOXAMIDE; N PROPYL 1,2,3,4 TETRAHYDRO 6 METHYL 2 THIOXO 4 PHENYLPYRIMIDINE 5 CARBOXAMIDE; PROPYL 1 METHYL 6 METHYL 4 PHENYL 2 OXO 1,2,3,4 TETRAHYDROPYRIMIDINE 5 CARBOXYLATE; PYRIMIDINE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; AUTOMATION; BIGINELLI REACTION; DEPROTECTION REACTION; DRUG PURIFICATION; DRUG STRUCTURE; DRUG SYNTHESIS; HYDROGENATION; MICROWAVE RADIATION; MITSUNOBU REACTION; PRIORITY JOURNAL;

EID: 33645999986     PISSN: 00404020     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tet.2005.12.061     Document Type: Article

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