High-speed combinatorial synthesis utilizing microwave irradiation

Current Opinion in Chemical Biology

Volumn 6, Issue 3, 2002, Pages 314-320

  Kappe, C Oliver ^a  

^a UNIVERSITY OF GRAZ   (Austria)

Author keywords

[No Author keywords available]

Indexed keywords

POLYMER;

AUTOMATION; COMBINATORIAL CHEMISTRY; INSTRUMENTATION; MICROWAVE COOKING; MICROWAVE IRRADIATION; REVIEW; SYNTHESIS; VELOCITY;

EID: 0036603599     PISSN: 13675931     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1367-5931(02)00306-X     Document Type: Review

References (33)

1. Microwave assisted organic synthesis - A review
2. Microwave-assisted high-speed chemistry: A new technique in drug discovery
3. Recent advances in microwave-assisted organic synthesis
4. A tentative rationalization of microwave effects in organic synthesis according to the reaction medium, and mechanistic considerations
5. Microwave assisted combinatorial chemistry. Synthesis of substituted pyridines
6. Dielectric parameters relevant to microwave dielectric heating
7. Functionalized polymers - Emerging versatile tools for solution-phase chemistry and automated parallel synthesis
8. Novel procedure for the synthesis of 1,3,4-oxadiazoles from 1,2-diacylhydrazines using polymer-supported Burgess reagent under microwave conditions
9. Synthesis of 1,3,4-oxadiazoles using polymer-supported reagents
10. A polymer-supported thionating reagent
11. Thermal- and microwave-assisted hydrogenation of electron-deficient alkenes using a polymer-supported hydrogen donor
12. An efficient combination of microwave dielectric heating and the use of solid-supported triphenylphosphine for Wittig reactions
13. Speeding up solid-phase chemistry by microwave irradiation. A tool for high-throughput synthesis
14. High-speed couplings and cleavages in microwave-heated, solid-phase reactions at high temperatures
15. The effect of microwave irradiation on carbodiimide-mediated esterifications on solid-support
16. Microwave-assisted high-speed parallel synthesis of 4-aryl-3,4-dihydropyrimidin-2(1H)-ones using a solventless Biginelli condensation protocol
17. Microwave-accelerated three-component condensation reaction on clay: Solvent-free synthesis of imidazo[1,2-a] annulated pyridines, pyrazines and pyrimidines
18. Microwave-assisted synthesis of substituted imidazoles on a solid support under solvent-free conditions
19. Microwave-assisted solvent-free parallel synthesis of thioamides
20. Rapid parallel synthesis utilizing microwave irradiation
21. Spatially addressed synthesis of amino- and amino-oxy-substituted 1,3,5-triazine arrays on polymeric membranes
22. Sequential nucleophilic substitution on halogenated triazines, pyrimidines, and purines: A novel approach to cyclic peptidomimetics
23. Rapid parallel synthesis of polymer-bound enones utilizing microwave-assisted solid-phase chemistry
24. Automated library generation using sequential microwave-assisted chemistry. Application toward the Biginelli multicomponent condensation
25. An efficient and fast procedure for the Hantzsch dihydropyridine synthesis under microwave conditions
26. Microwave-assisted synthesis of a [3+2] cycloaddition library
27. One-pot three-step solution phase synthesis of thiohydantoins using microwave heating
28. Microwave-assisted synthesis of 2-aminoquinolones
29. More microwave reactors required
30. Microwave parallel library generation: Comparison of a conventional- and microwave-generated substituted 4(5)-sulfanyl-1H-imidazole library