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Volumn 3, Issue 6, 2001, Pages 624-630

Automated library generation using sequential microwave-assisted chemistry. Application toward the Biginelli multicomponent condensation

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ARTICLE;

EID: 0001260317     PISSN: 15204766     EISSN: None     Source Type: Journal    
DOI: 10.1021/cc010044j     Document Type: Article
Times cited : (274)

References (36)
  • 1
    • 0029078472 scopus 로고    scopus 로고
    • Microwave assisted organic reactions
    • For general reviews, see the following. (a) Caddick, S. Microwave Assisted Organic Reactions. Tetrahedron 1995, 51, 10403-10432. Lidström, P.; Tierney, J.; Wathey, B.; Westman, J. Rapid and Achievable Chemistry with Microwave Assisted Organic Synthesis. Tetrahedron, in press.
    • (1995) Tetrahedron , vol.51 , pp. 10403-10432
    • Caddick, S.1
  • 2
    • 0029078472 scopus 로고    scopus 로고
    • Rapid and achievable chemistry with microwave assisted organic synthesis
    • in press
    • For general reviews, see the following. (a) Caddick, S. Microwave Assisted Organic Reactions. Tetrahedron 1995, 51, 10403-10432. Lidström, P.; Tierney, J.; Wathey, B.; Westman, J. Rapid and Achievable Chemistry with Microwave Assisted Organic Synthesis. Tetrahedron, in press.
    • Tetrahedron
    • Lidström, P.1    Tierney, J.2    Wathey, B.3    Westman, J.4
  • 4
    • 84924213784 scopus 로고
    • Developments in microwave-assisted organic chemistry
    • (c) Strauss, C. R.; Trainor, R. W. Developments in Microwave-Assisted Organic Chemistry. Aust. J. Chem. 1995, 48, 1665-1692.
    • (1995) Aust. J. Chem. , vol.48 , pp. 1665-1692
    • Strauss, C.R.1    Trainor, R.W.2
  • 5
    • 0033693921 scopus 로고    scopus 로고
    • Cycloadditions under microwave irradiation conditions: Methods and applications
    • Review: de la Hoz, A.; Díaz-Ortis, A.; Moreno, A.; Langa, F. Cycloadditions under Microwave Irradiation Conditions: Methods and Applications. Eur. J. Org. Chem. 2000, 3659-3673.
    • (2000) Eur. J. Org. Chem. , pp. 3659-3673
    • De La Hoz, A.1    Díaz-Ortis, A.2    Moreno, A.3    Langa, F.4
  • 6
    • 0033380451 scopus 로고    scopus 로고
    • Solvent-free synthesis of heterocycles using microwaves
    • Review: Varma, R. S. Solvent-Free Synthesis of Heterocycles Using Microwaves. J. Heterocycl. Chem. 1999, 36, 1565-1571.
    • (1999) J. Heterocycl. Chem. , vol.36 , pp. 1565-1571
    • Varma, R.S.1
  • 9
    • 0033444261 scopus 로고    scopus 로고
    • Solvent-free organic synthesis using supported reagents and microwave irradiation
    • Reviews: (a) Varma, R. S. Solvent-Free Organic Synthesis Using Supported Reagents and Microwave Irradiation. Green Chem. 1999, 43-55.
    • (1999) Green Chem. , pp. 43-55
    • Varma, R.S.1
  • 12
    • 0035341584 scopus 로고    scopus 로고
    • Microwave-assisted high-speed chemistry: A new technique in drug discovery
    • Larhed, M.; Hallberg, A. Microwave-Assisted High-Speed Chemistry: A New Technique in Drug Discovery. Drug Discovery Today 2001, 6, 406-416.
    • (2001) Drug Discovery Today , vol.6 , pp. 406-416
    • Larhed, M.1    Hallberg, A.2
  • 15
    • 0000176059 scopus 로고
    • Aldehyde-urea derivatives of aceto- and oxaloacetic acids
    • Biginelli, P. Aldehyde-Urea Derivatives of Aceto- and Oxaloacetic Acids. Gazz. Chim. Ital. 1893, 23, 360-413.
    • (1893) Gazz. Chim. Ital. , vol.23 , pp. 360-413
    • Biginelli, P.1
  • 16
    • 0027205552 scopus 로고
    • 100 years of the biginelli dihydropyrimidine synthesis
    • Review: Kappe, C. O. 100 Years of the Biginelli Dihydropyrimidine Synthesis. Tetrahedron 1993, 49, 6937-6963.
    • (1993) Tetrahedron , vol.49 , pp. 6937-6963
    • Kappe, C.O.1
  • 17
    • 0034518876 scopus 로고    scopus 로고
    • Recent advances in the Biginelli dihydropyrimidine synthesis. New tricks from an old dog
    • Review: Kappe, C. O. Recent Advances in the Biginelli Dihydropyrimidine Synthesis. New Tricks from an Old Dog. Acc. Chem. Res. 2000, 33, 879-888.
    • (2000) Acc. Chem. Res. , vol.33 , pp. 879-888
    • Kappe, C.O.1
  • 18
    • 0000512227 scopus 로고    scopus 로고
    • Multiple-component condensation strategies for combinatorial library synthesis
    • Armstrong, R. W.; Combs, A. P.; Tempest, P. A.; Brown, S. D.; Keating, T. A. Multiple-Component Condensation Strategies for Combinatorial Library Synthesis. Acc. Chem. Res. 1996, 29, 123-131.
    • (1996) Acc. Chem. Res. , vol.29 , pp. 123-131
    • Armstrong, R.W.1    Combs, A.P.2    Tempest, P.A.3    Brown, S.D.4    Keating, T.A.5
  • 19
    • 0032925557 scopus 로고    scopus 로고
    • Multi-component methodologies in solid-phase organic synthesis
    • Dax, S. L.; McNally, J. J.; Youngman, M. A. Multi-Component Methodologies in Solid-Phase Organic Synthesis. Curr. Med. Chem. 1999, 6, 255-270.
    • (1999) Curr. Med. Chem. , vol.6 , pp. 255-270
    • Dax, S.L.1    McNally, J.J.2    Youngman, M.A.3
  • 20
    • 0034519777 scopus 로고    scopus 로고
    • Biologically active dihydropyrimidones of the Biginelli-type. A literature survey
    • Kappe, C. O. Biologically Active Dihydropyrimidones of the Biginelli-Type. A Literature Survey. Eur. J. Med. Chem. 2000, 35, 1043-1052.
    • (2000) Eur. J. Med. Chem. , vol.35 , pp. 1043-1052
    • Kappe, C.O.1
  • 21
    • 0032847541 scopus 로고    scopus 로고
    • Microwave-assisted high-speed parallel synthesis of 4-aryl-3,4-dihydropyrimidin-2(1H)-ones using a solventless Biginelli condensation protocol
    • Kappe, C. O.; Kumar, D.; Varma, R. S. Microwave-Assisted High-Speed Parallel Synthesis of 4-Aryl-3,4-dihydropyrimidin-2(1H)-ones Using a Solventless Biginelli Condensation Protocol. Synthesis 1999, 1799-1803.
    • (1999) Synthesis , pp. 1799-1803
    • Kappe, C.O.1    Kumar, D.2    Varma, R.S.3
  • 23
    • 0034128574 scopus 로고    scopus 로고
    • 3,4-dihydropyrimidin-2(1H)-ones: Fast synthesis under microwave irradiation in solvent free conditions
    • Stefani, H. A.; Gatti, P. M. 3,4-Dihydropyrimidin-2(1H)-ones: Fast Synthesis under Microwave Irradiation in Solvent Free Conditions. Synth. Commun. 2000, 30, 2165-2173.
    • (2000) Synth. Commun. , vol.30 , pp. 2165-2173
    • Stefani, H.A.1    Gatti, P.M.2
  • 24
    • 0033826501 scopus 로고    scopus 로고
    • Microwave-assisted efficient synthesis of dihydropyrimidines: Improved high yielding protocol for the Biginelli reaction
    • Yadav, J. S.; Subba Reddy, B. V.; Jagan Reddy, E.; Ramalingarm, T. Microwave-Assisted Efficient Synthesis of Dihydropyrimidines: Improved High Yielding Protocol for the Biginelli Reaction. J. Chem. Res., Synop. 2000, 354-355.
    • (2000) J. Chem. Res., Synop. , pp. 354-355
    • Yadav, J.S.1    Subba Reddy, B.V.2    Jagan Reddy, E.3    Ramalingarm, T.4
  • 25
    • 0034236727 scopus 로고    scopus 로고
    • Microwave-mediated biginelli reactions revisited. On the nature of rate and yield enhancements
    • references therein
    • Stadler, A.; Kappe, C. O. Microwave-Mediated Biginelli Reactions Revisited. On the Nature of Rate and Yield Enhancements. J. Chem. Soc., Perkin Trans. 1 2000, 1363-1368 and references therein.
    • (2000) J. Chem. Soc., Perkin Trans. 1 , pp. 1363-1368
    • Stadler, A.1    Kappe, C.O.2
  • 26
    • 0035296681 scopus 로고    scopus 로고
    • Solution to the bottleneck in drug discovery
    • For a description of the Smith synthesizer, see the following. Johansson, H. A Solution to the Bottleneck in Drug Discovery. Am. Lab. 2001, 33 (10), 28-32.
    • (2001) Am. Lab. , vol.33 , Issue.10 , pp. 28-32
    • Johansson, H.A.1
  • 28
    • 0034674776 scopus 로고    scopus 로고
    • Lanthanide triflate catalyzed Biginelli reaction. One-pot synthesis of dihydropyrimidones under solvent-free conditions
    • Ma, Y.; Qian, C.; Wang, L.; Yang, M. Lanthanide Triflate Catalyzed Biginelli Reaction. One-Pot Synthesis of Dihydropyrimidones under Solvent-Free Conditions. J. Org. Chem. 2000, 65, 3864-3868.
    • (2000) J. Org. Chem. , vol.65 , pp. 3864-3868
    • Ma, Y.1    Qian, C.2    Wang, L.3    Yang, M.4
  • 29
    • 0034703416 scopus 로고    scopus 로고
    • Indium(III) chloride-catalyzed one-pot synthesis of 1,3-dicarbonyl compounds, aldehydes, and urea: An improved procedure for the biginelli reaction
    • Ranu, B. C.; Hajra, A.; Jana, U. Indium(III) Chloride-Catalyzed One-Pot Synthesis of 1,3-Dicarbonyl Compounds, Aldehydes, and Urea: An Improved Procedure for the Biginelli Reaction. J. Org. Chem. 2000, 65, 6270-6272.
    • (2000) J. Org. Chem. , vol.65 , pp. 6270-6272
    • Ranu, B.C.1    Hajra, A.2    Jana, U.3
  • 30
    • 0034684498 scopus 로고    scopus 로고
    • One-pot synthesis of 3,4-dihydropyrimidin-2(1H)-ones using lanthanum chloride as a catalyst
    • Lu, J.; Bai, Y.; Wang, Z.; Yang, B.; Ma, H. One-Pot Synthesis of 3,4-Dihydropyrimidin-2(1H)-ones Using Lanthanum Chloride as a Catalyst. Tetrahedron Lett. 2000, 41, 9075-9078.
    • (2000) Tetrahedron Lett. , vol.41 , pp. 9075-9078
    • Lu, J.1    Bai, Y.2    Wang, Z.3    Yang, B.4    Ma, H.5
  • 31
    • 0033958880 scopus 로고    scopus 로고
    • Iron(III)-catalyzed synthesis of dihydropyrimidinones. Improved conditions for the Biginelli reaction
    • Lu, J.; Ma, H. Iron(III)-Catalyzed Synthesis of Dihydropyrimidinones. Improved Conditions for the Biginelli Reaction. Synlett 2000, 63-64.
    • (2000) Synlett , pp. 63-64
    • Lu, J.1    Ma, H.2
  • 32
    • 0030732273 scopus 로고    scopus 로고
    • A reexamination of the mechanism of the Biginelli dihydropyrimidine synthesis. Support for an n-acyliminium ion intermediate
    • Kappe, C. O. A Reexamination of the Mechanism of the Biginelli Dihydropyrimidine Synthesis. Support for an N-Acyliminium Ion Intermediate. J. Org. Chem. 1997, 62, 7201-7204.
    • (1997) J. Org. Chem. , vol.62 , pp. 7201-7204
    • Kappe, C.O.1
  • 33
    • 0032600765 scopus 로고    scopus 로고
    • A combinatorial approach to recognition of chirality: Preparation of highly enantioselective aryl-dihydropyrimidine selectors for chiral HPLC
    • Lewandowski, K.; Murer, P.; Svec, F.; Fréchet, J. M. J. A Combinatorial Approach to Recognition of Chirality: Preparation of Highly Enantioselective Aryl-Dihydropyrimidine Selectors for Chiral HPLC. J. Comb. Chem. 1999, 1, 105-112.
    • (1999) J. Comb. Chem. , vol.1 , pp. 105-112
    • Lewandowski, K.1    Murer, P.2    Svec, F.3    Fréchet, J.M.J.4
  • 34
    • 0037660637 scopus 로고    scopus 로고
    • New regioselective multicomponent reaction: One pot synthesis of spiro heterobicyclic aliphatic rings
    • Byk, G.; Gottlieb, H. E.; Herscovici, J.; Mirkin, F. New Regioselective Multicomponent Reaction: One Pot Synthesis of Spiro Heterobicyclic Aliphatic Rings. J. Comb. Chem. 2000, 2, 732-735.
    • (2000) J. Comb. Chem. , vol.2 , pp. 732-735
    • Byk, G.1    Gottlieb, H.E.2    Herscovici, J.3    Mirkin, F.4
  • 35
    • 0035796960 scopus 로고    scopus 로고
    • Towards the synthesis of C-glycosylated dihydropyrimidine libraries via the three-component Biginelli reaction. A novel approach to artifical nucleosides
    • Dondoni, A.; Massi, A.; Sabbatini, S. Towards the Synthesis of C-Glycosylated Dihydropyrimidine Libraries via the Three-Component Biginelli Reaction. A Novel Approach to Artifical Nucleosides. Tetrahedron Lett. 2001, 42, 4495-4497.
    • (2001) Tetrahedron Lett. , vol.42 , pp. 4495-4497
    • Dondoni, A.1    Massi, A.2    Sabbatini, S.3
  • 36
    • 0041726749 scopus 로고    scopus 로고
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