Peptidyl-prolyl cis-trans isomerases (immunophilins) and their roles in parasite biochemistry, host-parasite interaction and antiparasitic drug action

International Journal for Parasitology

Volumn 36, Issue 3, 2006, Pages 261-276

  Bell, Angus ^a   Monaghan, Paul ^a,c   Page, Antony P ^b  

^a TRINITY COLLEGE DUBLIN   (Ireland)

^b UNIVERSITY OF GLASGOW   (United Kingdom)

^c TUFTS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Cyclophilin; Cyclosporin; FK506; FKBP; Protein folding; Rapamycin

Indexed keywords

ANTIPARASITIC AGENT; ASCOMYCIN; CYCLOPHILIN; CYCLOSPORIN A; FK 506 BINDING PROTEIN; IMMUNOPHILIN; IMMUNOSUPPRESSIVE AGENT; LACTONE DERIVATIVE; RAPAMYCIN; SDZ 215918; TSUKUBAENOLIDE; UNCLASSIFIED DRUG; VALSPODAR;

PARASITOLOGY;

CAENORHABDITIS ELEGANS; DRUG PROTEIN BINDING; ENZYME ACTIVITY; GENE EXPRESSION; GENETIC TRANSCRIPTION; HOST PARASITE INTERACTION; HUMAN; IC 50; IMMUNOMODULATION; NONHUMAN; NUCLEOTIDE SEQUENCE; PARASITE VIRULENCE; PATHOGENESIS; PHARMACOGENETICS; PROTEIN FOLDING; PROTEIN LOCALIZATION; PROTEIN TRANSPORT; REVIEW; RNA SPLICING; SEQUENCE HOMOLOGY; SEX DIFFERENTIATION; TOXOPLASMA GONDII; TOXOPLASMOSIS; TRYPANOSOMA CRUZI;

AMINO ACID SEQUENCE; ANIMALS; ANTIPARASITIC AGENTS; CAENORHABDITIS ELEGANS PROTEINS; CYCLOPHILINS; EUKARYOTA; GENES, HELMINTH; GENES, PROTOZOAN; HELMINTHS; HOST-PARASITE INTERACTIONS; HOST-PARASITE RELATIONS; IMMUNOPHILINS; PROTOZOA; PROTOZOAN PROTEINS; TACROLIMUS BINDING PROTEINS; TRANSCRIPTION, GENETIC;

ANIMALIA; CAENORHABDITIS ELEGANS; PROTOZOA; TOXOPLASMA GONDII; TRYPANOSOMA CRUZI; VERMES;

EID: 33644852955     PISSN: 00207519     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijpara.2005.11.003     Document Type: Review

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