Structural determinants of the anti-HIV activity of a CCR5 antagonist derived from Toxoplasma gondii

Journal of Biological Chemistry

Volumn 279, Issue 51, 2004, Pages 53635-53642

  Yarovinsky, Felix ^a   Andersen, John F ^b   King, Lisa R ^c   Caspar, Patricia ^a   Aliberti, Julio ^a,d   Golding, Hana ^c   Sher, Alan ^a  

^a NATIONAL INSTITUTES OF HEALTH   (United States)

^b NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

^c CENTER FOR BIOLOGICS EVALUATION AND RESEARCH   (United States)

^d DUKE UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; CELLS; IMMUNOLOGY; MOLECULAR BIOLOGY; MUTAGENESIS; PATHOLOGY; PROTEINS; PROTOZOA;

CHEMOKINE RECEPTOR CCR5; HUMAN IMMUNODEFICIENCY VIRUS 1 (HIV-1); MURINE DENDRITIC CELLS; TOXOPLASMA GONDII;

VIRUSES;

ANTI HUMAN IMMUNODEFICIENCY VIRUS AGENT; CHEMOKINE RECEPTOR CCR5; CYCLOPHILIN; CYCLOSPORIN A; INTERLEUKIN 12; RECEPTOR BLOCKING AGENT;

ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; DRUG ACTIVITY; ENZYME ACTIVITY; NONHUMAN; PLASMODIUM FALCIPARUM; PREDICTION; PRIORITY JOURNAL; PROTEIN FUNCTION; SITE DIRECTED MUTAGENESIS; STRUCTURE ANALYSIS; TOXOPLASMA GONDII;

AMINO ACID SEQUENCE; ANIMALS; ANTIVIRAL AGENTS; BINDING, COMPETITIVE; CYCLOPHILINS; CYCLOSPORINE; DNA MUTATIONAL ANALYSIS; DOSE-RESPONSE RELATIONSHIP, DRUG; HIV; INTERLEUKIN-12; KINETICS; LIGANDS; MICE; MICE, INBRED C57BL; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; MUTATION; PLASMIDS; PLASMODIUM FALCIPARUM; PROTEIN BINDING; PROTEIN CONFORMATION; RECEPTORS, CCR5; RECOMBINANT PROTEINS; SPLEEN; TOXOPLASMA; VACCINIA VIRUS;

HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS 1; MURINAE; PLASMODIUM FALCIPARUM; PROTOZOA; TOXOPLASMA GONDII;

EID: 11144234129     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M410550200     Document Type: Article

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