A Plasmodium falciparum FK506-binding protein (FKBP) with peptidyl-prolyl cis-trans isomerase and chaperone activities

Molecular and Biochemical Parasitology

Volumn 139, Issue 2, 2005, Pages 185-195

  Monaghan, Paul ^a   Bell, Angus ^a  

^a TRINITY COLLEGE DUBLIN   (Ireland)

Author keywords

FK506 binding protein; Malaria; Molecular chaperone; Plasmodium; Protein folding

Indexed keywords

CALCINEURIN; CHAPERONE; CYCLOPHILIN; CYCLOSPORIN A; FK 506 BINDING PROTEIN; PHOSPHATASE; PROTOZOAL PROTEIN; RAPAMYCIN; RECOMBINANT PROTEIN; TACROLIMUS;

AMINO TERMINAL SEQUENCE; ARTICLE; BINDING KINETICS; CARBOXY TERMINAL SEQUENCE; DRUG PROTEIN BINDING; ENZYME ACTIVITY; GENETIC DATABASE; GENOME ANALYSIS; MOLECULAR WEIGHT; NONHUMAN; NUCLEOTIDE SEQUENCE; PLASMODIUM FALCIPARUM; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN FAMILY; T LYMPHOCYTE; TETRATRICOPEPTIDE REPEAT;

AMINO ACID SEQUENCE; ANIMALS; IMMUNOSUPPRESSIVE AGENTS; MOLECULAR CHAPERONES; MOLECULAR SEQUENCE DATA; PEPTIDYLPROLYL ISOMERASE; PLASMODIUM FALCIPARUM; PROTEIN FOLDING; PROTOZOAN PROTEINS; RECOMBINANT PROTEINS; TACROLIMUS; TACROLIMUS BINDING PROTEINS;

PLASMODIUM FALCIPARUM;

EID: 12344264071     PISSN: 01666851     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.molbiopara.2004.10.007     Document Type: Article

References (47)

1. F.J. López-Antuñano, and G.A. Schmunis Plasmodia in humans J.P. Kreier Parasitic protozoa vol. 5 1993 Academic Press San Diego 135 266
2. J.G. Bremen The ears of the hippopotamus: manifestations, determinants, and estimates of the malaria burden Am J Trop Med Hyg 64S 2001 1 11
3. A. Bell, B. Wernli, and R.M. Franklin Roles of peptidyl-prolyl cis-trans isomerase and calcineurin in the mechanisms of antimalarial action of cyclosporin A, FK506, and rapamycin Biochem Pharmacol 48 1994 495 503
4. M.W. Harding, A. Galat, D.E. Uehling, and S.L. Schreiber A receptor for the immunosuppressant FK506 is a cis-trans peptidyl-prolyl isomerase Nature 341 1989 758 760
5. J.J. Siekierka, Hung SHY, M. Poe, C.S. Lin, and N.H. Sigal A cytosolic binding protein for the immunosuppressant FK506 has peptidyl-prolyl isomerase activity but is distinct from cyclophilin Nature 341 1989 755 757
6. G. Fischer, and T. Aumüller Regulation of peptide bond cis/trans isomerization by enzyme catalysis and its implication in physiological processes Rev Physiol Biochem Pharmacol 148 2003 105 150
7. J.E. Kay Structure-function relationships in the FK506-binding protein (FKBP) family of peptidylprolyl cis-trans isomerases Biochem J 314 1996 361 385
8. G.L. Blatch, and M. Lässle The tetratricopeptide repeat: a structural motif mediating protein-protein interactions Bioessays 21 1999 932 939
9. L.D. D'Andrea, and L. Regan TPR proteins: the versatile helix Trends Biochem Sci 28 2003 655 662
10. A. Galat, and S.M. Metcalfe Peptidylproline cis/trans isomerases Prog Biophys Mol Biol 63 1995 67 118
11. D. Pal, and P. Chakrabarti Cis peptide bonds in proteins: residues involved, their conformations, interactions and locations J Mol Biol 294 1999 271 288
12. C. Scholz, G. Stoller, T. Zarnt, G. Fischer, and F.X. Schmid Cooperation of enzymatic and chaperone functions of trigger factor in the catalysis of protein folding EMBO J 16 1997 54 58
13. A. Ideno, T. Yoshida, M. Furutani, and T. Maruyama The 28.3 kDa FK506 binding protein from a thermophilic archaeum, Methanobacterium thermoautotrophicum, protects the denaturation of proteins in vitro Eur J Biochem 267 2000 3139 3148
14. J.P. Arié, N. Sassoon, and J.M. Betton Chaperone function of FkpA, a heat shock prolyl isomerase, in the periplasm of Escherichia coli Mol Microbiol 39 2001 199 210
15. F. Pirkl, and J. Buchner Functional analysis of the Hsp90-assocaited human peptidyl prolyl cis/trans isomerases FKBP51, FKBP52 and Cyp40 J Mol Biol 308 2001 795 806
16. T. Kamphausen, J. Fanghänel, D. Neumann, B. Schulz, and J.U. Rahfeld Characterisation of Arabidopsis thaliana AtFKBP42 that is membrane-bound and interacts with Hsp90 Plant J 32 2002 263 276
17. R. Suzuki, K. Nagata, and F. Yumoto Three-dimensional solution structure of an archael FKBP with a dual function of peptidyl prolyl cis-trans isomerase and chaperone-like activities J Mol Biol 328 2003 1149 1160
18. T. Jayaraman, A.M. Brilliantes, and A.P. Timerman FK506 binding protein associated with the calcium release channel (ryanodine channel) J Biol Chem 267 1992 9474 9477
19. Brilliantes AMB, K. Ondraiš, and A. Scott Stabilisation of calcium release channel (ryanodine receptor) function by FK506-binding protein Cell 77 1994 513 523
20. A.M. Cameron, J.P. Steiner, D.M. Sabatini, A.I. Kaplin, L.D. Walensky, and S.H. Snyder Immunophilin FK506 binding protein associated with inositol 1,4,5-trisphosphate receptor modulates calcium flux Proc Natl Acad Sci USA 92 1995 1784 1788
21. A.M. Cameron, F.C. Nucifora, and E.T. Fung FKBP12 binds the inositol 1,4,5-trisphosphate receptor at leucine-proline (1400-1401) and anchors calcineurin to this FK506-like domain J Biol Chem 272 1997 27582 27588
22. T. Wang, B.Y. Li, and P.D. Danielson The immunophilin FKBP12 functions as a common inhibitor of the TGFβ family type I receptors Cell 86 1996 435 444
23. Y.G. Chen, F. Liu, and J. Massagué Mechanism of TGFβ receptor inhibition by FKBP12 EMBO J 16 1997 3866 3876
24. W.B. Pratt, and D.O. Toft Regulation of signalling protein function and trafficking by the hsp90/hsp70-based chaperone machinery Exp Biol Med 228 2003 111 133
25. A. Moro, F. Ruiz-Cabello, A. Fernandez-Cano, S.P. Stock, and A. Gonzalez Secretion by Trypanosoma cruzi of a peptidyl-prolyl cis-trans isomerase involved in cell infection EMBO J 14 1995 2483 2490
26. S.L. Schreiber, and G.R. Crabtree The mechanism of action of cyclosporin A and FK506 Immunol Today 13 1992 136 142
27. P.D. Braun, K.T. Barglow, and Y. Lin A bifunctional molecule that displays context-dependent cellular activity J Am Chem Soc 125 2003 7575 7580
28. A. Bell, B. Wernli, and R.M. Franklin Effects of microtubule inhibitors on protein synthesis in Plasmodium falciparum Parasitol Res 79 1993 146 152
29. A. Zuckerman Harvesting of Plasmodium falciparum with saponin Bull WHO 37 1967 431 436
30. T. Maniatis, E.F. Fritsch, and J. Sambrook Molecular cloning: a laboratory manual 1982 Cold Spring Harbor Laboratory Press
31. H.C. Birnboim, and J. Doly A rapid alkaline extraction procedure for the screening of recombinant plasmid DNA Nuclei Acid Res 7 1979 1513
32. M.M. Bradford A rapid and sensitive method for the quantitation of microgram quantities of protein utilising the principle of protein dye binding Anal Biochem 72 1976 248 254
33. J.L. Kofron, P. Kuzmic, V. Kishore, E. Colon-Bonilla, and D.H. Rich Determination of kinetic constants for peptidyl prolyl cis-trans isomerases by an improved spectrophotometric assay Biochemistry 30 1991 6127 6134
34. R.K. Harrison, and R.L. Stein Substrate specificities of the peptidyl prolyl cis-trans isomerase activities of cyclophilin and FK-506 binding protein: evidence for the existence of a family of distinct enzymes Biochemistry 29 1990 3813 3816
35. J. Buchner, H. Grallert, and U. Jakob Analysis of chaperone function using citrate synthase as nonnative substrate protein Method Enzymol 290 1998 323 338
36. F. Pirkl, E. Fischer, S. Modrow, and J. Buchner Localization of the chaperone domain of FKBP52 J Biol Chem 276 2001 37034 37041
37. U.C. Manning-Krieg, R. Henríquez, F. Cammas, P. Graff, S. Gavériaux, and N.R. Movva Purification of FKBP-70, a novel immunophilin from Saccharomyces cerevisiae, and cloning of its structural gene FPR3 FEBS Lett. 352 1994 98 103
38. G.D. van Duyne, R.F. Standaert, P.A. Karplus, S.L. Schreiber, and J. Clardy Atomic structure of the human FKBP-12 complexes with FK506 and rapamycin J Mol Biol 229 1993 105 124
39. H. Ke, and Q. Huai Structures of calcineurin and its complexes with immunophilins-immunosuppressants Biochem Biophys Res Commun 311 2003 1095 1102
40. M. Shirane, and K.I. Nakayama Inherent calcineurin inhibitor FKBP38 targets Bcl-2 to mitochondria and inhibts apoptosis Nature Cell Biol 5 2003 1 10
41. T.K. Li, S. Baksh, A.D. Cristillo, and B.E. Bierer Calcium- and FK506-independent interaction between immunophilin FKBP51 and calcineurin J Cell Biochem 84 2002 460 471
42. G. Baughman, G.L. Wiederrecht, F. Chang, M.M. Martin, and S. Bourgeois Tissue distribution and abundance of human FKBP51, an FK506-binding protein that can mediate calcineurin inhibition Biochem Biophys Res Commun 232 1997 437 443
43. J.S. Richardson β-Sheet topology and the relatedness of proteins Nature 268 1977 495 500
44. C.S. Gavigan, S.P. Kiely, J. Hirtzlin, and A. Bell Cyclosporin-binding proteins of Plasmodium falciparum Int J Parasitol 33 2003 987 996
45. A. Lorberg, and M.N. Hall TOR: the first 10 years Curr Opin Microbiol Immunol 279 2004 1 18
46. S. Dobson, T. May, and M. Berriman Characterization of protein ser/thr phosphatases of the malaria parasite, Plasmodium falciparum: inhibition of the parasite calcineurin by cyclophilin-cyclosporin complex Mol Biochem Parasitol 99 1999 167 181
47. R. Kumar, A. Musiyenko, A. Oldenburg, B. Adams, and S. Barik Post-translational generation of constitutively active cores from larger phosphatases in the malarial parasite Plasmodium falciparum: implications for proteomics BMC Mol Biol 5 2004 6