메뉴 건너뛰기




Volumn 39, Issue 3, 2003, Pages 193-203

From cells to signaling cascades: Manipulation of innate immunity by Toxoplasma gondii

Author keywords

Cytokine; Immune evasion; Infection protozoan

Indexed keywords

ADAPTOR PROTEIN; ARACHIDONATE 5 LIPOXYGENASE; CASPASE; CHEMOKINE RECEPTOR CCR5; CYCLOPHILIN; DIFFERENTIATION ANTIGEN; DNA BINDING PROTEIN; G PROTEIN COUPLED RECEPTOR; GAMMA ACTIVATED FACTOR, 91 KD; GAMMA INTERFERON; GAMMA-ACTIVATED FACTOR, 91-KD; HEAT SHOCK PROTEIN 70; I KAPPA B ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; IMMUNOGLOBULIN RECEPTOR; INTERLEUKIN 10; INTERLEUKIN 12; LIPOXIN; MAJOR HISTOCOMPATIBILITY ANTIGEN; MYELOID DIFFERENTIATION FACTOR 88; PARASITE ANTIGEN; PROSTAGLANDIN E2; STAT1 PROTEIN; STAT4 PROTEIN; TOLL LIKE RECEPTOR; TRANSACTIVATOR PROTEIN; UNCLASSIFIED DRUG;

EID: 0345016346     PISSN: 09288244     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0928-8244(03)00279-7     Document Type: Short Survey
Times cited : (94)

References (96)
  • 3
    • 0035218427 scopus 로고    scopus 로고
    • High levels of congenital transmission of Toxoplasma gondii in a commercial sheep flock
    • Duncanson P., Terry R.S., Smith J.E., Hide G. High levels of congenital transmission of Toxoplasma gondii in a commercial sheep flock. Int. J. Parasitol. 31:2001;1699-1703.
    • (2001) Int. J. Parasitol. , vol.31 , pp. 1699-1703
    • Duncanson, P.1    Terry, R.S.2    Smith, J.E.3    Hide, G.4
  • 4
    • 0036803121 scopus 로고    scopus 로고
    • Toxoplasma gondii: Transmission, diagnosis and prevention
    • Hill D., Dubey J.P. Toxoplasma gondii: transmission, diagnosis and prevention. Clin. Microbiol. Infect. 8:2002;634-640.
    • (2002) Clin. Microbiol. Infect. , vol.8 , pp. 634-640
    • Hill, D.1    Dubey, J.P.2
  • 5
    • 0036155839 scopus 로고    scopus 로고
    • Host cell invasion by the opportunistic pathogen Toxoplasma gondii
    • Carruthers V.B. Host cell invasion by the opportunistic pathogen Toxoplasma gondii. Acta Trop. 81:2002;111-122.
    • (2002) Acta Trop. , vol.81 , pp. 111-122
    • Carruthers, V.B.1
  • 6
    • 0031958697 scopus 로고    scopus 로고
    • Structures of Toxoplasma gondii tachyzoites, bradyzoites, and sporozoites and biology and development of tissue cysts
    • Dubey J.P., Lindsay D.S., Speer C.A. Structures of Toxoplasma gondii tachyzoites, bradyzoites, and sporozoites and biology and development of tissue cysts. Clin. Microbiol. Rev. 11:1998;267-299.
    • (1998) Clin. Microbiol. Rev. , vol.11 , pp. 267-299
    • Dubey, J.P.1    Lindsay, D.S.2    Speer, C.A.3
  • 7
    • 0031736936 scopus 로고    scopus 로고
    • Regulation and function of T cell-mediated immunity during Toxoplasma gondii infection
    • Denkers E.Y., Gazzinelli R.T. Regulation and function of T cell-mediated immunity during Toxoplasma gondii infection. Clin. Microbiol. Rev. 11:1998;569-588.
    • (1998) Clin. Microbiol. Rev. , vol.11 , pp. 569-588
    • Denkers, E.Y.1    Gazzinelli, R.T.2
  • 9
    • 0036893663 scopus 로고    scopus 로고
    • The function of gamma interferon-inducible GTP-binding protein IGTP in host resistance to Toxoplasma gondii is Stat1 dependent and requires expression in both hematopoietic and non-hematopoietic cellular compartments
    • Collazo C.M., Yap G.S., Hieny S., Caspar P., Feng C.G., Taylor G.A., Sher A. The function of gamma interferon-inducible GTP-binding protein IGTP in host resistance to Toxoplasma gondii is Stat1 dependent and requires expression in both hematopoietic and non-hematopoietic cellular compartments. Infect. Immun. 70:2002;6933-6939.
    • (2002) Infect. Immun. , vol.70 , pp. 6933-6939
    • Collazo, C.M.1    Yap, G.S.2    Hieny, S.3    Caspar, P.4    Feng, C.G.5    Taylor, G.A.6    Sher, A.7
  • 11
    • 0034283962 scopus 로고    scopus 로고
    • Identification of STAT4-dependent and independent mechanisms of resistance to Toxoplasma gondii
    • Cai G., Radzanowski T., Villegas E.N., Kastelein R., Hunter C.A. Identification of STAT4-dependent and independent mechanisms of resistance to Toxoplasma gondii. J. Immunol. 165:2000;2619-2627.
    • (2000) J. Immunol. , vol.165 , pp. 2619-2627
    • Cai, G.1    Radzanowski, T.2    Villegas, E.N.3    Kastelein, R.4    Hunter, C.A.5
  • 12
    • 0032762620 scopus 로고    scopus 로고
    • Cell-mediated immunity to Toxoplasma gondii: Initiation, regulation and effector function
    • Yap G.S., Sher A. Cell-mediated immunity to Toxoplasma gondii: initiation, regulation and effector function. Immunobiology. 201:1999;240-247.
    • (1999) Immunobiology , vol.201 , pp. 240-247
    • Yap, G.S.1    Sher, A.2
  • 13
    • 0031964559 scopus 로고    scopus 로고
    • Immunoregulation during toxoplasmosis
    • Alexander J., Hunter C.A. Immunoregulation during toxoplasmosis. Chem. Immunol. 70:1998;81-102.
    • (1998) Chem. Immunol. , vol.70 , pp. 81-102
    • Alexander, J.1    Hunter, C.A.2
  • 14
    • 0023895411 scopus 로고
    • Interferon-γ: The major mediator of resistance against Toxoplasma gondii
    • Suzuki Y., Orellana M.A., Schreiber R.D., Remington J.S. Interferon-γ: The major mediator of resistance against Toxoplasma gondii. Science. 240:1988;516-518.
    • (1988) Science , vol.240 , pp. 516-518
    • Suzuki, Y.1    Orellana, M.A.2    Schreiber, R.D.3    Remington, J.S.4
  • 15
    • 0030294163 scopus 로고    scopus 로고
    • In the absence of endogenous IFN-γ mice develop unimpaired IL-12 responses to Toxoplasma gondii while failing to control acute infection
    • Scharton-Kersten T.M., Wynn T.A., Denkers E.Y., Bala S., Showe L., Grunvald E., Hieny S., Gazzinelli R.T., Sher A. In the absence of endogenous IFN-γ mice develop unimpaired IL-12 responses to Toxoplasma gondii while failing to control acute infection. J. Immunol. 157:1996;4045-4054.
    • (1996) J. Immunol. , vol.157 , pp. 4045-4054
    • Scharton-Kersten, T.M.1    Wynn, T.A.2    Denkers, E.Y.3    Bala, S.4    Showe, L.5    Grunvald, E.6    Hieny, S.7    Gazzinelli, R.T.8    Sher, A.9
  • 16
    • 0026749880 scopus 로고
    • + T lymphocytes is required to reactivate chronic infection with Toxoplasma gondii
    • + T lymphocytes is required to reactivate chronic infection with Toxoplasma gondii. J. Immunol. 149:1992;175-180.
    • (1992) J. Immunol. , vol.149 , pp. 175-180
    • Gazzinelli, R.1    Xu, Y.2    Hieny, S.3    Cheever, A.4    Sher, A.5
  • 17
    • 0027241272 scopus 로고
    • Toxoplasma gondii induces a T-independent IFN-γ response in NK cells which requires both adherent accessory cells and TNF-α
    • Sher A., Oswald I.O., Hieny S., Gazzinelli R.T. Toxoplasma gondii induces a T-independent IFN-γ response in NK cells which requires both adherent accessory cells and TNF-α J. Immunol. 150:1993;3982-3989.
    • (1993) J. Immunol. , vol.150 , pp. 3982-3989
    • Sher, A.1    Oswald, I.O.2    Hieny, S.3    Gazzinelli, R.T.4
  • 18
    • 0028272528 scopus 로고
    • Production of gamma interferon by natural killer cells from Toxoplasma gondii-infected SCID mice: Regulation by interleukin-10, interleukin-12, and tumor necrosis factor alpha
    • Hunter C.A., Subauste C.S., Van Cleave V.H., Remington J.S. Production of gamma interferon by natural killer cells from Toxoplasma gondii-infected SCID mice: regulation by interleukin-10, interleukin-12, and tumor necrosis factor alpha. Infect. Immun. 62:1994;2818-2824.
    • (1994) Infect. Immun. , vol.62 , pp. 2818-2824
    • Hunter, C.A.1    Subauste, C.S.2    Van Cleave, V.H.3    Remington, J.S.4
  • 19
    • 0035313545 scopus 로고    scopus 로고
    • Inducible expression of Stat4 in dendritic cells and macrophages and its critical role in innate and adaptive immune responses
    • Fukao T., Frucht D.M., Yap G., Gadina M., O'Shea J.J., Koyasu S. Inducible expression of Stat4 in dendritic cells and macrophages and its critical role in innate and adaptive immune responses. J. Immunol. 166:2001;4446-4455.
    • (2001) J. Immunol. , vol.166 , pp. 4446-4455
    • Fukao, T.1    Frucht, D.M.2    Yap, G.3    Gadina, M.4    O'Shea, J.J.5    Koyasu, S.6
  • 20
    • 0027264849 scopus 로고
    • IL-12 is required for the T-cell independent induction of IFN-γ by an intracellular parasite and induces resistance in T-cell-deficient hosts
    • Gazzinelli R.T., Hieny S., Wynn T., Wolf S., Sher A. IL-12 is required for the T-cell independent induction of IFN-γ by an intracellular parasite and induces resistance in T-cell-deficient hosts. Proc. Natl. Acad. Sci. USA. 90:1993;6115-6119.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 6115-6119
    • Gazzinelli, R.T.1    Hieny, S.2    Wynn, T.3    Wolf, S.4    Sher, A.5
  • 21
    • 0000060327 scopus 로고    scopus 로고
    • In vivo microbial stimulation induces rapid CD40L-independent production of IL-12 by dendritic cells and their re-distribution to T cell areas
    • Reis e Sousa C., Hieny S., Scharton-Kersten T., Jankovic D., Charest H., Germain R.N., Sher A. In vivo microbial stimulation induces rapid CD40L-independent production of IL-12 by dendritic cells and their re-distribution to T cell areas. J. Exp. Med. 186:1997;1819-1829.
    • (1997) J. Exp. Med. , vol.186 , pp. 1819-1829
    • Reis Sousa E, C.1    Hieny, S.2    Scharton-Kersten, T.3    Jankovic, D.4    Charest, H.5    Germain, R.N.6    Sher, A.7
  • 22
    • 0033567090 scopus 로고    scopus 로고
    • Murine neutrophil stimulation by Toxoplasma gondii antigen drives high level production of IFN-γ-independent IL-12
    • Bliss S.K., Zhang Y., Denkers E.Y. Murine neutrophil stimulation by Toxoplasma gondii antigen drives high level production of IFN-γ- independent IL-12. J. Immunol. 163:1999;2081-2088.
    • (1999) J. Immunol. , vol.163 , pp. 2081-2088
    • Bliss, S.K.1    Zhang, Y.2    Denkers, E.Y.3
  • 24
    • 0034445617 scopus 로고    scopus 로고
    • Interleukin-18 (IL-18) enhances innate IL-12-mediated resistance to Toxoplasma gondii
    • Cai G., Kastelein R., Hunter C.A. Interleukin-18 (IL-18) enhances innate IL-12-mediated resistance to Toxoplasma gondii. Infect. Immun. 68:2000;6932-6938.
    • (2000) Infect. Immun. , vol.68 , pp. 6932-6938
    • Cai, G.1    Kastelein, R.2    Hunter, C.A.3
  • 25
    • 0038326688 scopus 로고    scopus 로고
    • Cutting edge: Role of IL-27/WSX-1 signaling for induction of T-bet through activation of STAT1 during initial Th1 commitment
    • Takeda A., Hamano S., Yamanaka A., Hanada T., Ishibashi T., Mak T.W., Yoshimura A., Yoshida H. Cutting edge: Role of IL-27/WSX-1 signaling for induction of T-bet through activation of STAT1 during initial Th1 commitment. J. Immunol. 170:2003;4886-4890.
    • (2003) J. Immunol. , vol.170 , pp. 4886-4890
    • Takeda, A.1    Hamano, S.2    Yamanaka, A.3    Hanada, T.4    Ishibashi, T.5    Mak, T.W.6    Yoshimura, A.7    Yoshida, H.8
  • 26
    • 0034662258 scopus 로고    scopus 로고
    • IL-12 is required for the maintenance of IFN-γ production in T cells mediating chronic resistance to the intracellular pathogen, Toxoplasma gondii
    • Yap G., Pesin M., Sher A. IL-12 is required for the maintenance of IFN-γ production in T cells mediating chronic resistance to the intracellular pathogen, Toxoplasma gondii. J. Immunol. 165:2000;628-631.
    • (2000) J. Immunol , vol.165 , pp. 628-631
    • Yap, G.1    Pesin, M.2    Sher, A.3
  • 27
    • 0030970867 scopus 로고    scopus 로고
    • Inducible nitric oxide is essential for host control of persistent but not acute infection with the intracellular pathogen Toxoplasma gondii
    • Scharton-Kersten T., Yap G., Magram J., Sher A. Inducible nitric oxide is essential for host control of persistent but not acute infection with the intracellular pathogen Toxoplasma gondii. J. Exp. Med. 185:1997;1-13.
    • (1997) J. Exp. Med. , vol.185 , pp. 1-13
    • Scharton-Kersten, T.1    Yap, G.2    Magram, J.3    Sher, A.4
  • 28
    • 0035898464 scopus 로고    scopus 로고
    • Inactivation of LRG-47 and IRG-47 reveals a family of interferon-γ-inducible genes with essential, pathogen-specific roles in resistance to infection
    • Collazo C.M., Yap G.S., Sempowski G.D., Lusby K.C., Tessarollo L., Vande Woude G.F., Sher A., Taylor G.A. Inactivation of LRG-47 and IRG-47 reveals a family of interferon-γ-inducible genes with essential, pathogen-specific roles in resistance to infection. J. Exp. Med. 194:2001;181-187.
    • (2001) J. Exp. Med. , vol.194 , pp. 181-187
    • Collazo, C.M.1    Yap, G.S.2    Sempowski, G.D.3    Lusby, K.C.4    Tessarollo, L.5    Vande Woude, G.F.6    Sher, A.7    Taylor, G.A.8
  • 29
    • 0033526013 scopus 로고    scopus 로고
    • Effector cells of both nonhemopoietic and hemopoietic origin are required for interferon (IFN)-γ and tumor necrosis factor (TNF)-α-dependent host resistance to the intracellular pathogen, Toxoplasma gondii
    • Yap G.S., Sher A. Effector cells of both nonhemopoietic and hemopoietic origin are required for interferon (IFN)-γ and tumor necrosis factor (TNF)-α-dependent host resistance to the intracellular pathogen, Toxoplasma gondii. J. Exp. Med. 189:1999;1083-1091.
    • (1999) J. Exp. Med. , vol.189 , pp. 1083-1091
    • Yap, G.S.1    Sher, A.2
  • 30
    • 0027939611 scopus 로고
    • Parasite-induced IL-12 stimulates early IFN-γ synthesis and resistance during acute infection with Toxoplasma gondii
    • Gazzinelli R.T., Wysocka M., Hayashi S., Denkers E.Y., Hieny S., Caspar P., Trinchieri G., Sher A. Parasite-induced IL-12 stimulates early IFN-γ synthesis and resistance during acute infection with Toxoplasma gondii. J. Immunol. 153:1994;2533-2543.
    • (1994) J. Immunol. , vol.153 , pp. 2533-2543
    • Gazzinelli, R.T.1    Wysocka, M.2    Hayashi, S.3    Denkers, E.Y.4    Hieny, S.5    Caspar, P.6    Trinchieri, G.7    Sher, A.8
  • 32
    • 1842417179 scopus 로고    scopus 로고
    • Role of interleukin-10 in regulation of T-cell-dependent and T-cell-independent mechanisms of resistance to Toxoplasma gondii
    • Neyer L.E., Grunig G., Fort M., Remington J.S., Rennick D., Hunter C.A. Role of interleukin-10 in regulation of T-cell-dependent and T-cell-independent mechanisms of resistance to Toxoplasma gondii. Infect. Immun. 65:1997;1675-1682.
    • (1997) Infect. Immun. , vol.65 , pp. 1675-1682
    • Neyer, L.E.1    Grunig, G.2    Fort, M.3    Remington, J.S.4    Rennick, D.5    Hunter, C.A.6
  • 33
    • 0029841124 scopus 로고    scopus 로고
    • + T cell-dependent, IFN-γ-mediated necrosis of the small intestine with genetic susceptibility of mice to peroral infection with Toxoplasma gondii
    • + T cell-dependent, IFN-γ-mediated necrosis of the small intestine with genetic susceptibility of mice to peroral infection with Toxoplasma gondii. J. Exp. Med. 184:1996;597-607.
    • (1996) J. Exp. Med. , vol.184 , pp. 597-607
    • Liesenfeld, O.1    Kosek, J.2    Remington, J.S.3    Suzuki, Y.4
  • 34
    • 0034658617 scopus 로고    scopus 로고
    • IL-10 is required for prevention of necrosis in the small intestine and mortality in both genetically resistant BALB/c and susceptible C57BL/6 mice following peroral infection with Toxoplasma gondii
    • Suzuki Y., Sher A., Yap G., Park D., Ellis Neyer L., Liesenfeld O., Fort M., Kang H., Gufwoli E. IL-10 is required for prevention of necrosis in the small intestine and mortality in both genetically resistant BALB/c and susceptible C57BL/6 mice following peroral infection with Toxoplasma gondii. J. Immunol. 164:2000;5375-5382.
    • (2000) J. Immunol. , vol.164 , pp. 5375-5382
    • Suzuki, Y.1    Sher, A.2    Yap, G.3    Park, D.4    Ellis Neyer, L.5    Liesenfeld, O.6    Fort, M.7    Kang, H.8    Gufwoli, E.9
  • 36
    • 0035879107 scopus 로고    scopus 로고
    • IFN-γ overproduction and high level apoptosis are associated with high but not low virulence Toxoplasma gondii infection
    • Gavrilescu L.C., Denkers E.Y. IFN-γ overproduction and high level apoptosis are associated with high but not low virulence Toxoplasma gondii infection. J. Immunol. 167:2001;902-909.
    • (2001) J. Immunol. , vol.167 , pp. 902-909
    • Gavrilescu, L.C.1    Denkers, E.Y.2
  • 38
    • 0036342974 scopus 로고    scopus 로고
    • Population biology of Toxoplasma gondii and its relevance to human infection: Do different strains cause different disease
    • Boothroyd J.C., Grigg M.E. Population biology of Toxoplasma gondii and its relevance to human infection: do different strains cause different disease. Curr. Opin. Microbiol. 5:2002;438-442.
    • (2002) Curr. Opin. Microbiol. , vol.5 , pp. 438-442
    • Boothroyd, J.C.1    Grigg, M.E.2
  • 39
    • 0036716776 scopus 로고    scopus 로고
    • Mechanism of entry determines ability of Toxoplasma gondii to inhibit macrophage proinflammatory cytokine production
    • Butcher B.A., Denkers E.Y. Mechanism of entry determines ability of Toxoplasma gondii to inhibit macrophage proinflammatory cytokine production. Infect. Immun. 70:2002;5216-5224.
    • (2002) Infect. Immun. , vol.70 , pp. 5216-5224
    • Butcher, B.A.1    Denkers, E.Y.2
  • 41
    • 0032979758 scopus 로고    scopus 로고
    • Sensitized lymphocytes and CD40 ligation augment interleukin-12 production by human dendritic cells in response to Toxoplasma gondii
    • Seguin R., Kasper L.H. Sensitized lymphocytes and CD40 ligation augment interleukin-12 production by human dendritic cells in response to Toxoplasma gondii. J. Infect. Dis. 179:1999;467-474.
    • (1999) J. Infect. Dis. , vol.179 , pp. 467-474
    • Seguin, R.1    Kasper, L.H.2
  • 43
    • 0037438643 scopus 로고    scopus 로고
    • CD154 plays a central role in regulating dendritic cell activation during infections that induce Th1 or Th2 responses
    • Straw A.D., MacDonald A.S., Denkers E.Y., Pearce E.J. CD154 plays a central role in regulating dendritic cell activation during infections that induce Th1 or Th2 responses. J. Immunol. 170:2003;727-734.
    • (2003) J. Immunol. , vol.170 , pp. 727-734
    • Straw, A.D.1    MacDonald, A.S.2    Denkers, E.Y.3    Pearce, E.J.4
  • 44
    • 0031660821 scopus 로고    scopus 로고
    • Murine dendritic cells pulsed in vitro with Toxoplasma gondii antigens induce protective immunity in vivo
    • Bourguin I., Moser M., Buzoni-Gatel D., Tielemens F., Bout D., Urbain J., Leo L. Murine dendritic cells pulsed in vitro with Toxoplasma gondii antigens induce protective immunity in vivo. Infect. Immun. 66:1998;4867-4874.
    • (1998) Infect. Immun. , vol.66 , pp. 4867-4874
    • Bourguin, I.1    Moser, M.2    Buzoni-Gatel, D.3    Tielemens, F.4    Bout, D.5    Urbain, J.6    Leo, L.7
  • 45
    • 0033564304 scopus 로고    scopus 로고
    • Human polymorphonuclear leukocytes produce IL-12, TNF-α, and the chemokines macrophage-inflammatory protein-1α and -1β in response to Toxoplasma gondii antigens
    • Bliss S.K., Marshall A.J., Zhang Y., Denkers E.Y. Human polymorphonuclear leukocytes produce IL-12, TNF-α, and the chemokines macrophage-inflammatory protein-1α and -1β in response to Toxoplasma gondii antigens. J. Immunol. 162:1999;7369-7375.
    • (1999) J. Immunol. , vol.162 , pp. 7369-7375
    • Bliss, S.K.1    Marshall, A.J.2    Zhang, Y.3    Denkers, E.Y.4
  • 46
    • 0034668049 scopus 로고    scopus 로고
    • Rapid recruitment of neutrophils with prestored IL-12 during microbial infection
    • Bliss S.K., Butcher B.A., Denkers E.Y. Rapid recruitment of neutrophils with prestored IL-12 during microbial infection. J. Immunol. 165:2000;4515-4521.
    • (2000) J. Immunol. , vol.165 , pp. 4515-4521
    • Bliss, S.K.1    Butcher, B.A.2    Denkers, E.Y.3
  • 47
    • 0025763220 scopus 로고
    • Release of both preformed and newly synthesized tumor necrosis factor a (TNF-α)/cachectin by mouse mast cells stimulated via the FcεRI. a mechanism for the sustained activation of mast cell-derived TNF-α during IgE-dependent biological responses
    • Gordon J.R., Galli S.J. Release of both preformed and newly synthesized tumor necrosis factor a (TNF-α)/cachectin by mouse mast cells stimulated via the FcεRI. A mechanism for the sustained activation of mast cell-derived TNF-α during IgE-dependent biological responses. J. Exp. Med. 174:1991;103-107.
    • (1991) J. Exp. Med. , vol.174 , pp. 103-107
    • Gordon, J.R.1    Galli, S.J.2
  • 48
    • 0035576223 scopus 로고    scopus 로고
    • CXCR2 deficiency confers impaired neutrophil recruitment and increased susceptibility during Toxoplasma gondii infection
    • Del Rio L., Bennouna S., Salinas J., Denkers E.Y. CXCR2 deficiency confers impaired neutrophil recruitment and increased susceptibility during Toxoplasma gondii infection. J. Immunol. 167:2001;6503-6509.
    • (2001) J. Immunol. , vol.167 , pp. 6503-6509
    • Del Rio, L.1    Bennouna, S.2    Salinas, J.3    Denkers, E.Y.4
  • 49
    • 0345690207 scopus 로고    scopus 로고
    • Cross talk in the innate immune system: Neutrophils instruct early recruitment and activation of dendritic cells during microbial infection
    • In press.
    • Bennouna, S., Bliss, S.K., Curiel, T.J. and Denkers, E.Y. (2003) Cross talk in the innate immune system: neutrophils instruct early recruitment and activation of dendritic cells during microbial infection. J. Immunol. In press.
    • (2003) J. Immunol.
    • Bennouna, S.1    Bliss, S.K.2    Curiel, T.J.3    Denkers, E.Y.4
  • 50
    • 0141799941 scopus 로고    scopus 로고
    • Production of IL-12 and other cytokines during microbial infection
    • Denkers E.Y., Del Rio L.D., Bennouna S. Production of IL-12 and other cytokines during microbial infection. Chem. Immunol. 83:2003;95-114.
    • (2003) Chem. Immunol. , vol.83 , pp. 95-114
    • Denkers, E.Y.1    Del Rio, L.D.2    Bennouna, S.3
  • 51
    • 0034921188 scopus 로고    scopus 로고
    • Neutrophil depletion during Toxoplasma gondii infection leads to impaired immunity and lethal systemic pathology
    • Bliss S.K., Gavrilescu L.C., Alcaraz A., Denkers E.Y. Neutrophil depletion during Toxoplasma gondii infection leads to impaired immunity and lethal systemic pathology. Infect. Immun. 69:2001;4898-4905.
    • (2001) Infect. Immun. , vol.69 , pp. 4898-4905
    • Bliss, S.K.1    Gavrilescu, L.C.2    Alcaraz, A.3    Denkers, E.Y.4
  • 52
    • 0030924023 scopus 로고    scopus 로고
    • Initiation of T-helper cell immunity to Candida albicans by IL-12: The role of neutrophils
    • Romani L., Bistoni F., Puccetti P. Initiation of T-helper cell immunity to Candida albicans by IL-12: the role of neutrophils. Chem. Immunol. 68:1997;110-135.
    • (1997) Chem. Immunol. , vol.68 , pp. 110-135
    • Romani, L.1    Bistoni, F.2    Puccetti, P.3
  • 54
    • 0035887505 scopus 로고    scopus 로고
    • CD11c(+)B220(+)Gr-1(+) cells in mouse lymph nodes and spleen display characteristics of plasmacytoid dendritic cells
    • Nakano H., Yanagita M., Gunn M.D. CD11c(+)B220(+)Gr-1(+) cells in mouse lymph nodes and spleen display characteristics of plasmacytoid dendritic cells. J. Exp. Med. 194:2001;1171-1178.
    • (2001) J. Exp. Med. , vol.194 , pp. 1171-1178
    • Nakano, H.1    Yanagita, M.2    Gunn, M.D.3
  • 56
    • 0030664056 scopus 로고    scopus 로고
    • ICSBP-deficient mice display impaired resistance to intracellular infection due to a primary defect in IL-12 p40 induction
    • Scharton-Kersten T., Contursi C., Masumi A., Sher A., Ozato K. ICSBP-deficient mice display impaired resistance to intracellular infection due to a primary defect in IL-12 p40 induction. J. Exp. Med. 186:1997;1523-1534.
    • (1997) J. Exp. Med. , vol.186 , pp. 1523-1534
    • Scharton-Kersten, T.1    Contursi, C.2    Masumi, A.3    Sher, A.4    Ozato, K.5
  • 57
    • 0037032471 scopus 로고    scopus 로고
    • IRF-8/ICSBP and IRF-1 cooperatively stimulate mouse IL-12 promoter activity in macrophages
    • Masumi A., Tamaoki S., Ming Wang I., Ozato K., Komuro K. IRF-8/ICSBP and IRF-1 cooperatively stimulate mouse IL-12 promoter activity in macrophages. FEBS Lett. 531:2002;348-353.
    • (2002) FEBS Lett. , vol.531 , pp. 348-353
    • Masumi, A.1    Tamaoki, S.2    Ming Wang, I.3    Ozato, K.4    Komuro, K.5
  • 58
    • 0029143632 scopus 로고
    • Regulation of interleukin 12 p40 expression through an NF-κB half-site
    • Murphy T., Cleveland M., Kulezka P., Magram J., Murphy K. Regulation of interleukin 12 p40 expression through an NF-κB half-site. Mol. Cell. Biol. 15:1995;5258-5267.
    • (1995) Mol. Cell. Biol. , vol.15 , pp. 5258-5267
    • Murphy, T.1    Cleveland, M.2    Kulezka, P.3    Magram, J.4    Murphy, K.5
  • 59
    • 0030872393 scopus 로고    scopus 로고
    • Multiple control elements mediate activation of the murine and human interleukin 12 p40 promoters: Evidence of functional synergy between C/EBP and Rel proteins
    • Plevy S.E., Gemberling J.H.M., Hsu S., Dorner A.J., Smale S.T. Multiple control elements mediate activation of the murine and human interleukin 12 p40 promoters: evidence of functional synergy between C/EBP and Rel proteins. Mol. Cell. Biol. 17:1997;4572-4588.
    • (1997) Mol. Cell. Biol. , vol.17 , pp. 4572-4588
    • Plevy, S.E.1    Gemberling, J.H.M.2    Hsu, S.3    Dorner, A.J.4    Smale, S.T.5
  • 61
    • 0037097795 scopus 로고    scopus 로고
    • Cutting edge: MyD88 is required for resistance to Toxoplasma gondii infection and regulates parasite-induced IL-12 production by dendritic cells
    • Scanga C.A., Aliberti J., Jankovic D., Tilloy F., Bennouna S., Denkers E.Y., Medzhitov R., Sher A. Cutting edge: MyD88 is required for resistance to Toxoplasma gondii infection and regulates parasite-induced IL-12 production by dendritic cells. J. Immunol. 168:2002;5997-6001.
    • (2002) J. Immunol. , vol.168 , pp. 5997-6001
    • Scanga, C.A.1    Aliberti, J.2    Jankovic, D.3    Tilloy, F.4    Bennouna, S.5    Denkers, E.Y.6    Medzhitov, R.7    Sher, A.8
  • 62
    • 0024450377 scopus 로고
    • Evidence for glycosyl-phosphatidylinositol anchoring of Toxoplasma gondii major surface proteins
    • Tomavo S., Schwartz R.T., Dubremetz J.-F. Evidence for glycosyl-phosphatidylinositol anchoring of Toxoplasma gondii major surface proteins. Mol. Cell. Biol. 9:1989;4576-4580.
    • (1989) Mol. Cell. Biol. , vol.9 , pp. 4576-4580
    • Tomavo, S.1    Schwartz, R.T.2    Dubremetz, J.-F.3
  • 64
    • 0031570514 scopus 로고    scopus 로고
    • Glycosylphosphotidylinositol-anchored mucin-like glycoproteins isolated from Trypanosoma cruzi trypomastigotes initiate the synthesis of proinflammatory cytokines by macrophages
    • Camargo M.M., Almeida I.C., Pereira M.E.S., Ferguson M.A.J., Travassos L.R., Gazzinelli R.T. Glycosylphosphotidylinositol-anchored mucin-like glycoproteins isolated from Trypanosoma cruzi trypomastigotes initiate the synthesis of proinflammatory cytokines by macrophages. J. Immunol. 158:1997;5890-5901.
    • (1997) J. Immunol. , vol.158 , pp. 5890-5901
    • Camargo, M.M.1    Almeida, I.C.2    Pereira, M.E.S.3    Ferguson, M.A.J.4    Travassos, L.R.5    Gazzinelli, R.T.6
  • 65
    • 0034084163 scopus 로고    scopus 로고
    • Phosphorylation meets ubiquitination: The control of NF-κB activity
    • Karin M., Ben-Neriah Y. Phosphorylation meets ubiquitination: the control of NF-κB activity. Annu. Rev. Immunol. 18:2000;621-663.
    • (2000) Annu. Rev. Immunol. , vol.18 , pp. 621-663
    • Karin, M.1    Ben-Neriah, Y.2
  • 67
    • 0037087436 scopus 로고    scopus 로고
    • Identification of c-Rel-dependent and -independent pathways of Il-12 production during infectious and inflammatory stimuli
    • Mason N., Aliberti J., Caamano J.C., Liou H.C., Hunter C.A. Identification of c-Rel-dependent and -independent pathways of Il-12 production during infectious and inflammatory stimuli. J. Immunol. 168:2002;2590-2594.
    • (2002) J. Immunol. , vol.168 , pp. 2590-2594
    • Mason, N.1    Aliberti, J.2    Caamano, J.C.3    Liou, H.C.4    Hunter, C.A.5
  • 68
    • 0035983295 scopus 로고    scopus 로고
    • NF-κB family of transcription factors: Central regulators of innate and adaptive immune functions
    • Caamano J., Hunter C.A. NF-κB family of transcription factors: central regulators of innate and adaptive immune functions. Clin. Microbiol. Rev. 15:2002;414-429.
    • (2002) Clin. Microbiol. Rev. , vol.15 , pp. 414-429
    • Caamano, J.1    Hunter, C.A.2
  • 71
    • 0035089760 scopus 로고    scopus 로고
    • Regulation of interleukin-12 production by G-protein-coupled receptors
    • Braun M.C., Kelsall B.L. Regulation of interleukin-12 production by G-protein-coupled receptors. Microb. Infect. 3:2001;99-107.
    • (2001) Microb. Infect. , vol.3 , pp. 99-107
    • Braun, M.C.1    Kelsall, B.L.2
  • 72
    • 0027382381 scopus 로고
    • Host resistance to Toxoplasma gondii: Model for studying the selective induction of cell-mediated immunity by intracellular parasites
    • Gazzinelli R.T., Denkers E.Y., Sher A. Host resistance to Toxoplasma gondii: Model for studying the selective induction of cell-mediated immunity by intracellular parasites. Infect. Agents Dis. 2:1993;139-149.
    • (1993) Infect. Agents Dis. , vol.2 , pp. 139-149
    • Gazzinelli, R.T.1    Denkers, E.Y.2    Sher, A.3
  • 73
    • 0028158318 scopus 로고
    • Leishmania promastigotes evade interleukin 12 (IL-12) induction by macrophages and stimulate a broad range of cytokines from CD4+ T cells during initiation of infection
    • Reiner S.L., Zheng S., Wang Z.-E., Stowring L., Locksley R.M. Leishmania promastigotes evade interleukin 12 (IL-12) induction by macrophages and stimulate a broad range of cytokines from CD4+ T cells during initiation of infection. J. Exp. Med. 179:1994;447-456.
    • (1994) J. Exp. Med. , vol.179 , pp. 447-456
    • Reiner, S.L.1    Zheng, S.2    Wang, Z.-E.3    Stowring, L.4    Locksley, R.M.5
  • 74
    • 0030021084 scopus 로고    scopus 로고
    • Leishmania promastigotes selectively inhibit interleukin 12 induction in bone marrow-derived macrophages from susceptible and resistant mice
    • Carrera L., Gazzinelli R.T., Badolato R., Hieny S., Muller W., Kuhn R., Sacks D.L. Leishmania promastigotes selectively inhibit interleukin 12 induction in bone marrow-derived macrophages from susceptible and resistant mice. J. Exp. Med. 183:1996;515-526.
    • (1996) J. Exp. Med. , vol.183 , pp. 515-526
    • Carrera, L.1    Gazzinelli, R.T.2    Badolato, R.3    Hieny, S.4    Muller, W.5    Kuhn, R.6    Sacks, D.L.7
  • 76
    • 0037303310 scopus 로고    scopus 로고
    • In the belly of the beast: Subversion of macrophage proinflammatory signaling cascades during Toxoplasma gondii infection
    • Denkers E.Y., Kim L., Butcher B.A. In the belly of the beast: subversion of macrophage proinflammatory signaling cascades during Toxoplasma gondii infection. Cell. Microbiol. 5:2003;75-83.
    • (2003) Cell. Microbiol. , vol.5 , pp. 75-83
    • Denkers, E.Y.1    Kim, L.2    Butcher, B.A.3
  • 77
    • 0031782098 scopus 로고    scopus 로고
    • Down-regulation of MHC class II molecules and inability to up-regulate class I molecules in murine macrophages after infection with Toxoplasma gondii
    • Luder C.G.K., Lang T., Beurle B., Gross U. Down-regulation of MHC class II molecules and inability to up-regulate class I molecules in murine macrophages after infection with Toxoplasma gondii. Clin. Exp. Immunol. 112:1998;308-316.
    • (1998) Clin. Exp. Immunol. , vol.112 , pp. 308-316
    • Luder, C.G.K.1    Lang, T.2    Beurle, B.3    Gross, U.4
  • 78
    • 0037221830 scopus 로고    scopus 로고
    • Toxoplasma gondii inhibits MHC class II expression in neural antigen-presenting cells by down-regulating the class II transactivator CIITA
    • Luder C.G.K., Lang C., Giraldo-Velasquez M., Algner M., Gerdes J., Gross U. Toxoplasma gondii inhibits MHC class II expression in neural antigen-presenting cells by down-regulating the class II transactivator CIITA. J. Neuroimmunol. 134:2003;12-24.
    • (2003) J. Neuroimmunol. , vol.134 , pp. 12-24
    • Luder, C.G.K.1    Lang, C.2    Giraldo-Velasquez, M.3    Algner, M.4    Gerdes, J.5    Gross, U.6
  • 79
    • 0343867201 scopus 로고    scopus 로고
    • Toxoplasma gondii down-regulates MHC class II gene expression and antigen presentation by murine macrophages via interference with nuclear translocation of STAT1a
    • Luder C.G.K., Walter W., Beuerle B., Maeurer M.J., Gross U. Toxoplasma gondii down-regulates MHC class II gene expression and antigen presentation by murine macrophages via interference with nuclear translocation of STAT1a. Eur. J. Immunol. 31:2001;1475-1484.
    • (2001) Eur. J. Immunol. , vol.31 , pp. 1475-1484
    • Luder, C.G.K.1    Walter, W.2    Beuerle, B.3    Maeurer, M.J.4    Gross, U.5
  • 80
    • 0036081269 scopus 로고    scopus 로고
    • Host-pathogen interactions: Subversion and utilization of the NF-κB pathway during infection
    • Tato C.M., Hunter C.A. Host-pathogen interactions: subversion and utilization of the NF-κB pathway during infection. Infect. Immun. 70:2002;3311-3317.
    • (2002) Infect. Immun. , vol.70 , pp. 3311-3317
    • Tato, C.M.1    Hunter, C.A.2
  • 81
    • 0035881856 scopus 로고    scopus 로고
    • Toxoplasma gondii tachyzoites inhibit proinflammatory cytokine induction in infected macrophages by preventing nuclear translocation of the transcription factor NFκB
    • Butcher B.A., Kim L., Johnson P.F., Denkers E.Y. Toxoplasma gondii tachyzoites inhibit proinflammatory cytokine induction in infected macrophages by preventing nuclear translocation of the transcription factor NFκB. J. Immunol. 167:2001;2193-2201.
    • (2001) J. Immunol. , vol.167 , pp. 2193-2201
    • Butcher, B.A.1    Kim, L.2    Johnson, P.F.3    Denkers, E.Y.4
  • 83
    • 0037100504 scopus 로고    scopus 로고
    • Heat shock protein 70 is a potential virulence factor in murine Toxoplasma gondii infection via immunomodulation of host NF-κB and nitric oxide
    • Dobbin C.A., smith N.C., Johnson A.M. Heat shock protein 70 is a potential virulence factor in murine Toxoplasma gondii infection via immunomodulation of host NF-κB and nitric oxide. J. Immunol. 169:2002;958-965.
    • (2002) J. Immunol. , vol.169 , pp. 958-965
    • Dobbin, C.A.1    Smith, N.C.2    Johnson, A.M.3
  • 84
    • 0031414944 scopus 로고    scopus 로고
    • Suppression of glial nitric oxide synthase induction by heat shock: Effects on proteolytic degradation of IkappaB-alpha
    • Feinstein D.L., Galea E., Reis D.J. Suppression of glial nitric oxide synthase induction by heat shock: effects on proteolytic degradation of IkappaB-alpha. Nitric Oxide. 1:1997;167-176.
    • (1997) Nitric Oxide , vol.1 , pp. 167-176
    • Feinstein, D.L.1    Galea, E.2    Reis, D.J.3
  • 85
    • 0032519416 scopus 로고    scopus 로고
    • Toxoplasma gondii-infected cells are resistant to multiple inducers of apoptosis
    • Nash P.B., Purner M.B., Leon R.P., Clarke P., Duke R.C., Curiel T.J. Toxoplasma gondii-infected cells are resistant to multiple inducers of apoptosis. J. Immunol. 160:1998;1824-1830.
    • (1998) J. Immunol. , vol.160 , pp. 1824-1830
    • Nash, P.B.1    Purner, M.B.2    Leon, R.P.3    Clarke, P.4    Duke, R.C.5    Curiel, T.J.6
  • 86
    • 0034766428 scopus 로고    scopus 로고
    • Inhibition of host cell apoptosis by Toxoplasma gondii is accompanied by reduced activation of the caspase cascade and alterations of poly(ADP-ribose) polymerase expression
    • Goebel S., Gross U., Luder C.G.K. Inhibition of host cell apoptosis by Toxoplasma gondii is accompanied by reduced activation of the caspase cascade and alterations of poly(ADP-ribose) polymerase expression. J. Cell Sci. 114:2001;3495-3505.
    • (2001) J. Cell Sci. , vol.114 , pp. 3495-3505
    • Goebel, S.1    Gross, U.2    Luder, C.G.K.3
  • 87
    • 0034766428 scopus 로고    scopus 로고
    • Inhibition of host cell apoptosis by Toxoplasma gondii is accompanied by reduced activation of the caspase cascade and alterations of poly(ADP-ribose) polymerase activation
    • Goebel S.G., Gross U., Luder C.G.K. Inhibition of host cell apoptosis by Toxoplasma gondii is accompanied by reduced activation of the caspase cascade and alterations of poly(ADP-ribose) polymerase activation. J. Cell Sci. 114:2001;3495-3505.
    • (2001) J. Cell Sci. , vol.114 , pp. 3495-3505
    • Goebel, S.G.1    Gross, U.2    Luder, C.G.K.3
  • 88
    • 0033230388 scopus 로고    scopus 로고
    • Paralysis of dendritic cell IL-12 production by microbial products prevents infection-based immunopathology
    • Reis e Sousa C., Yap G., Schultz O., Rogers N., Schito M., Aliberti J., Hieny S., Sher A. Paralysis of dendritic cell IL-12 production by microbial products prevents infection-based immunopathology. Immunity. 11:1999;637-647.
    • (1999) Immunity , vol.11 , pp. 637-647
    • Reis Sousa E, C.1    Yap, G.2    Schultz, O.3    Rogers, N.4    Schito, M.5    Aliberti, J.6    Hieny, S.7    Sher, A.8
  • 89
    • 0036141930 scopus 로고    scopus 로고
    • Lipoxin-mediated inhibition of IL-12 production by DCs: A mechanism for regulation of microbial immunity
    • Aliberti J., Reis e Sousa C., Serhan C.N., Sher A. Lipoxin-mediated inhibition of IL-12 production by DCs: a mechanism for regulation of microbial immunity. Nat. Immunol. 3:2002;76-82.
    • (2002) Nat. Immunol. , vol.3 , pp. 76-82
    • Aliberti, J.1    Reis Sousa E, C.2    Serhan, C.N.3    Sher, A.4
  • 90
    • 0037020861 scopus 로고    scopus 로고
    • 4 is an endogenous regulator of IL-12 production and immunopathology in Toxoplasma gondii infection
    • 4 is an endogenous regulator of IL-12 production and immunopathology in Toxoplasma gondii infection. J. Exp. Med. 196:2002;1253-1262.
    • (2002) J. Exp. Med. , vol.196 , pp. 1253-1262
    • Aliberti, J.1    Serhan, C.2    Sher, A.3
  • 91
    • 0036252392 scopus 로고    scopus 로고
    • Positive and negative regulation of pathogen induced dendritic cell function by G-protein coupled receptors
    • Aliberti J., Sher A. Positive and negative regulation of pathogen induced dendritic cell function by G-protein coupled receptors. Mol. Immunol. 38:2001;891-893.
    • (2001) Mol. Immunol. , vol.38 , pp. 891-893
    • Aliberti, J.1    Sher, A.2
  • 93
    • 0032425062 scopus 로고    scopus 로고
    • Helicobacter hepaticus triggers colitis in specific-pathogen-free interleukin-10 (IL-10)-deficient mice through an IL-12 and gamma interferon-dependent mechanism
    • Kullberg M.C., Ward J.M., Gorelick P.L., Caspar P., Hieny S., Cheever A., Jankovic D., Sher A. Helicobacter hepaticus triggers colitis in specific-pathogen-free interleukin-10 (IL-10)-deficient mice through an IL-12 and gamma interferon-dependent mechanism. Infect. Immun. 66:1998;5157-5166.
    • (1998) Infect. Immun. , vol.66 , pp. 5157-5166
    • Kullberg, M.C.1    Ward, J.M.2    Gorelick, P.L.3    Caspar, P.4    Hieny, S.5    Cheever, A.6    Jankovic, D.7    Sher, A.8
  • 95
    • 0032947846 scopus 로고    scopus 로고
    • Transmembrane insertion of the Toxoplasma gondii GRA5 protein occurs after soluble secretion into the host cell
    • Lecordier L., Mercier C., Sibley L.D., Cesbron-Delauw M.-F. Transmembrane insertion of the Toxoplasma gondii GRA5 protein occurs after soluble secretion into the host cell. Mol. Biol. Cell. 10:1999;1277-1287.
    • (1999) Mol. Biol. Cell , vol.10 , pp. 1277-1287
    • Lecordier, L.1    Mercier, C.2    Sibley, L.D.3    Cesbron-Delauw, M.-F.4
  • 96
    • 0028134806 scopus 로고
    • The Toxoplasma gondii rhoptry protein ROP 2 is inserted into the parasitophorous vacuole membrane, surrounding the intracellular parasite, and is exposed to the host cell cytoplasm
    • Beckers C.J.M., Dubremetz J.-F., Mercereau-Puijalon O., Joiner K.A. The Toxoplasma gondii rhoptry protein ROP 2 is inserted into the parasitophorous vacuole membrane, surrounding the intracellular parasite, and is exposed to the host cell cytoplasm. J. Cell Biol. 127:1994;947-961.
    • (1994) J. Cell Biol. , vol.127 , pp. 947-961
    • Beckers, C.J.M.1    Dubremetz, J.-F.2    Mercereau-Puijalon, O.3    Joiner, K.A.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.