Molecular and biochemical characterization of a protein cyclophilin from the nematode Haemonchus contortus

Parasitology Research

Volumn 96, Issue 4, 2005, Pages 199-205

  Valle, Cristiana ^a   Troiani, Anna Rita ^a   Lazzaretti, Patrizio ^a   Bouvier, Jacques ^b   Cioli, Donato ^a   Klinkert, Mo Quen ^c  

^a CNR   (Italy)

^b Animal Health Division   (Switzerland)

^c BERNHARD NOCHT INSTITUTE FOR TROPICAL MEDICINE   (Germany)

Author keywords

Cyclophilin; Haemonchus contortus; PPIase activity; RNA binding

Indexed keywords

ANTISERUM; CYCLOPHILIN; CYCLOSPORIN A; IMMUNOSUPPRESSIVE AGENT; NUCLEIC ACID; RECOMBINANT PROTEIN;

AMINO TERMINAL SEQUENCE; ARTICLE; BINDING AFFINITY; BIOCHEMISTRY; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; ENZYME ACTIVITY; GENE EXPRESSION; GENE SEQUENCE; HAEMONCHUS CONTORTUS; MOLECULAR CLONING; MOLECULAR RECOGNITION; MOLECULE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN MOTIF;

AMINO ACID MOTIFS; AMINO ACID SEQUENCE; ANIMALS; CLONING, MOLECULAR; CYCLOPHILINS; DNA, HELMINTH; GENES, HELMINTH; HAEMONCHUS; MOLECULAR SEQUENCE DATA; PEPTIDYLPROLYL ISOMERASE; RECOMBINANT PROTEINS; RNA, HELMINTH;

HAEMONCHUS CONTORTUS;

EID: 21644454692     PISSN: 09320113     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00436-005-1329-3     Document Type: Article

References (23)

1. Galat A (2003) Peptidylprolyl cis/trans isomerases (immunophilins): Biological diversity - targets - functions. Curr Top Med Chem 3:1315-1347
2. Handschumacher RE, Harding MW, Rice J, Drugge RJ (1984) Cyclophilin: a specific cytosolic binding protein for Cyclosporin A. Science 226:544-547
3. Takahashi N, Hayano T, Suzuki M (1989) Peptidyl-prolyl cis-trans isomerase is the cyclosporin A-binding protein cyclophilin. Nature 337:473-475
4. Freskgard PO, Bergenhem N, Jonsson BH, Svensson M, Carlsson U (1992) Isomerase and chaperone activity of prolyl isomerase in the folding of carbonic anhydrase. Science 258(5081):466-468
5. Baker EK, Colley NJ, Zuker CS (1994) The cyclophilin homolog NinaA functions as a chaperone, forming a stable complex in vivo with its protein target rhodopsin. EMBO J 13:4886-4895
6. Harding MW, Galat A, Uehling DE, Schreiber SL (1989) A receptor for the immunosuppressant FK506 is a cis-trans peptidyl-prolyl isomerase. Nature 341:758-760
7. Klinkert MQ, Bugli F, Engels B, Carrasquillo E, Valle C, Cioli D (1995) Characterization of a Schistosoma mansoni cDNA encoding a B-like cyclophilin and its expression in Escherichia coli. Mol Biochem Parasitol 75:99-111
8. Vaitukaitis J, Robbins JB, Nieschlag E, Ross GT (1971) A method for producing specific antisera with small doses of immunogen. J Clin Endocr 33:983-991
9. Sugita M, Sugiura M (1994) The existence of eukaryotic ribonucleoprotein consensus sequence-type RNA-binding proteins in a prokaryote, Synechococcus 6301. Nucleic Acids Res 22:25-31
10. Khattab A, Pica-Mattoccia L, Klinkert MQ, Wenger R, Cioli D (1998) Cyclosporins: lack of correlation between antischistosomal properties and inhibition of cyclophilin isomerase activity. Exp Parasitol 90:103-109
11. Anderson M, Fair K, Amero S, Nelson S, Harte PJ, Diaz MO (2002) A new family of cyclophilins with an RNA recognition motif that interact with members of the trx/MLL protein family in Drosophila and human cells. Dev Genes Evol 212:107-113
12. Shieh BH, Stamnes MA, Seavello S, Harris GL, Zuker CS (1989) The ninaA gene required for visual transduction in Drosophila encodes a homologue of cyclosporin A-binding protein. Nature 338:67-70
13. Schreiber SL, Crabtree GR (1992) The mechanism of action of cyclosporin A and FK506. Immunol Today 13:136-142
14. Franke EK, Luban J (1995) Cyclophilin and gag in HIV-1 replication and pathogenesis. Adv Exp Med Biol 374:217-228
15. Montague JW, Hughes FM Jr, Cidlowski JA (1997) Native recombinant cyclophilins A, B, and C degrade DNA independently of peptidylprolyl cis-trans-isomerase activity. Potential roles of cyclophilins in apoptosis. J Biol Chem 272:6677-6684
16. Rycyzyn MA, Clevenger CV (2002) The intranuclear prolactin/ cyclophilin B complex as a transcriptional inducer. Proc Natl Acad Sci U S A 99:6790-6795
17. Hoffmann K, Handschumacher RE (1995) Cyclophilin-40: evidence for a dimeric complex with hsp90. Biochem J 307:5-8
18. Crompton M, Ellinger H, Costi A (1988) Inhibition by cyclosporin A of a Ca2+-dependent pore in heart mitochondria activated by inorganic phosphate and oxidative stress. Biochem J 255:357-360
19. Kenan DJ, Query CC, Keene JD (1991) RNA recognition: towards identifying determinants of specificity. Trends Biochem Sci 16:214-220
20. Zeng L, Zhou Z, Xu J, Zhao W, Wang W, Huang Y, Cheng C, Xu M, Xie Y, Mao Y (2001) Molecular cloning, structure and expression of a novel nuclear RNA-binding cyclophilin-like gene (PPIL4) from human fetal brain. Cytogenet Cell Genet 95:43-47
21. Krzywicka A, Beisson J, Keller AM, Cohen J, Jerka-Dziadosz M, Klotz C (2001) KIN241: a gene involved in cell morphogenesis in Paramecium tetraurelia reveals a novel protein family of cyclophilin-RNA interacting proteins (CRIPs) conserved from fission yeast to man. Mol Microbiol 42:257-267
22. Zorio DA, Blumenthal T (1999) U2AF35 is encoded by an essential gene clustered in an operon with RRM/cyclophilin in Caenorhabditis elegans. RNA 5:487-494
23. Teigelkamp S, Achsel T, Mundt C, Gothel SF, Cronshagen U, Lane WS, Marahiel M, Luhrmann R (1998) The 20 kD protein of human [U4/U6.U5] tri-snRNPs is a novel cyclophilin that forms a complex with the U4/U6-specific 60 kD and 90 kD proteins. RNA 4:127-141