A cyclosporin A-sensitive small molecular weight cyclophilin of filarial parasites

Molecular and Biochemical Parasitology

Volumn 79, Issue 2, 1996, Pages 235-241

  Ma, Dong ^a   Hong, Xiqiang ^a   Raghavan, Nithyakalyani ^b   Scott, Alan L ^b   McCarthy, James S ^c   Nutman, Thomas B ^c   Williams, Steven A ^d   Carlow, Clotilde K S ^a  

^a NEW ENGLAND BIOLABS   (United States)

^b JOHNS HOPKINS BLOOMBERG SCHOOL OF PUBLIC HEALTH   (United States)

^c NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

^d SMITH COLLEGE   (United States)

Author keywords

Brugia malayi; Cyclophilin; Cyclosporin A; Dirofilaria immitis; Onchocerca volvulus; Peptidyl prolyl cis trans isomerase

Indexed keywords

CYCLOPHILIN; CYCLOSPORIN A;

ARTICLE; BRUGIA MALAYI; CONTROLLED STUDY; DIROFILARIA IMMITIS; DRUG SENSITIVITY; ECHINOCOCCUS GRANULOSUS; ENZYME ACTIVITY; ENZYME ANALYSIS; FILARIA; HUMAN; MOLECULAR WEIGHT; NONHUMAN; ONCHOCERCA VOLVULUS; PLASMODIUM FALCIPARUM; PRIORITY JOURNAL; SCHISTOSOMA MANSONI; TOXOPLASMA GONDII;

BRUGIA MALAYI; DIROFILARIA IMMITIS; ECHINOCOCCUS GRANULOSUS; FILARIA; ONCHOCERCA VOLVULUS; PLASMODIUM FALCIPARUM; SCHISTOSOMA MANSONI; TOXOPLASMA GONDII;

EID: 0030221873     PISSN: 01666851     EISSN: None     Source Type: Journal    
DOI: 10.1016/0166-6851(96)02654-0     Document Type: Article

References (35)

1. [1] Rassow, J.M., Mohrs, K., Koidl, S., Barthelmess, I.B., Pfanner, N. and Tropschug, M. (1995) Cyclophilin 20 is involved in mitochondrial protein folding in co-operation with molecular chaperones Hsp70 and Hsp60. Mol. Cell Biol. 15, 2654-2662.
2. [2] Matouschek, A., Rospert, S., Schmid, K., Glick, B.S. and Schatz, G. (1995) Cyclophilin catalyses protein folding in yeast mitochondria. Proc. Natl. Acad. Sci. USA 92, 6319-6323.
3. [3] Handschumacher, R.E., Harding, M.W., Rice, J. and Drugge, R.J. (1984) Cyclophilin: a specific cytosolic binding protein for cyclosporin A. Science 226, 544-547.
4. [4] Fischer, G., Wittmann-Liebold, B., Lang, K., Kiefhaber, T. and Schmid, F.X. (1989) Cyclophilin and peptidyl-prolyl cis-trans isomerase are probably identical proteins. Nature 337, 476-478.
5. [5] Chappell, L.H. and Wastling, J.L. (1992) Cyclosporin A: antiparasitic drug, modulator of the host-parasite relationship and immunosuppressant. Parasitology 105, S25-S40.
6. [6] Page, A.P., Kumar, S. and Carlow, C.K.S. (1995) Parasite cyclophilins and antiparasite activity of cyclosporin A. Parasitol. Today 11; 385-388.
7. [7] Chappell, L.H., Liu, J.F. and Penlington, M.C. (1993) Effects of cyclosporin A on Schistosoma and Fasciola in vivo and in vitro: mode of action. J. Cell. Biochem. Suppl. 17C, 114.
8. [8] Bell, A., Wernli, B. and Franklin, R.M. (1994) Roles of peptidyl-prolyl cis-trans isomerase and calcineurin in the mechanisms of antimalarial action of cyclosporin A, FK506, and rapamycin. Biochem. Pharmacol. 48, 495-503.
9. [9] Koletsky, A.J., Harding, M.W. and Handschumacher, R.E. (1986) Cyclophilin: distribution and variant properties in normal and neoplastic tissues. J. Immunol. 137, 1054-1059.
10. [10] Kiang, D.T., Karim, A.M. and Loverde, P.T. (1996) Identification and characterization of a Schistosoma mansoni p17.7, a cyclophilin. Mol. Biochem. Parasitol. 76, 73-82.
11. [11] Klinkert, M.Q., Bugli. F., Engels, B., Carrasquillo, E., Valle, C. and Cioli, D. (1995) Characterization of a Schistosoma mansoni cDNA encoding a B-like cyclophilin and its expression in Escherichia coli. Mol. Biochem. Parasitol. 75, 99-111.
12. [12] Lightowlers, M.W., Haralambous, A. and Rickard, M.D. (1989) Amino acid sequence homology between cyclophilin and a cDNA-cloned antigen of Echinococcus granulosus. Mol. Biochem. Parasitol. 36, 287-290.
13. [13] Argaet, V.P. and Mitchell, G.F. (1992) Cyclophilin of Schistosoma japonicum. J. Parasitol. 78, 660-664.
14. [14] High, K.P., Joiner, K.A. and Handschumacher, R.E. (1994) Isolation, cDNA sequences, and biochemical characterization of the major cyclosporin-binding proteins of Toxoplasma gondii. J. Biol. Chem. 269, 9105-9112.
15. [15] Reddy, G.R. (1995) Cloning and characterization of a Plasmodium falciparum cyclophilin gene that is stage-specifically expressed. Mol. Biochem. Parasitol. 73, 111-121.
16. [16] Page, A.P., Landry, D., Wilson, G.G. and Carlow, C.K.S. (1995) Molecular characterization of a cyclosporin A-insensitive cyclophilin from the parasitic nematode Brugia malayi. Biochemistry 34, 11545-11550.
17. [17] Bueding, E., Hawkins, J. and Cha, Y.-N. (1981) Antischistosomal effects of cyclosporin A. Agents Actions 11, 380-383.
18. [18] Mack, D.G. and McLeod, R. (1984) New micromethod to study the effect of antimicrobial agents on Toxoplasma gondii: comparison of sulfadoxine and sulfadiazine individually and in combination with pyrimethamine and study of clindamycin, metronidazole, and cyclosporin A. Antimicrob. Chemother. 26, 26-30.
19. [19] McCabe, R.E., Luft, B.J. and Remington, J.S. (1986) The effects of cyclosporin on Toxoplasma gondii in vivo and in vitro. Transplantation 41, 611-615.
20. [20] Thommen-Scott, K. (1981) Antimalarial activity of cyclosporin A. Agents Actions 11, 770-773.
21. [21] Bergsma, D.K., Eder, C., Gross, M., Kersten, H., Sylvester, D., Appelbaum, E., Cusimano, D., Livi, G.P., McLaughlin, M.M., Kasyanl, K., Porter, T.G., Silverman, C., Dunnington, D., Hand, A., Prichett, W.P., Bossard, M.J., Brandt, M. and Levy., M. (1991) The cyclophilin multigene family of peptidyl-prolyl isomerases. Characterization of three separate human isoforms. J. Biol. Chem. 266, 23204-23214.
22. [22] Ghosh, I., Raghavan, N., FitzGerald, P.C. and Scott, A.L. (1995) Nucleoside diphosphate kinase from the parasitic nematode Brugia malayi. Gene 164, 261-266.
23. [23] Blaxter, M.L., Raghavan, N., Ghosh, I., Guiliano, D., Lu, W., Williams, S.A., Slatko, B. and Scott, A.L. (1996) Genes expressed in Brugia malayi infective third stage larvae. Mol. Biochem. Parasitol., 77, 77-94.
24. [24] Elson, L.H., Guderian, R.H., Araujo, E., Bradley, J.E., Days, A. and Nutman, T.B. (1994) Immunity to onchocerciasis: identification of a putatively immune population in a hyperendemic area of Ecuador. J. Infect. Dis. 169, 588-594.
25. [25] Sambrook, J., Fritsch, E.F. and Maniatis, T. (1989) Molecular Cloning. A Laboratory Manual, 2nd edn. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY.
26. [26] Takacs, A.M., Denker, J.A., Perrine, K.G., Maroney, P.A. and Nilsen, T. (1988) A 22 nucleotide spliced leader sequence in the human parasitic nematode Brugia malayi is identical to the trans-spliced leader exon in Caenorhabditis elegans. Proc. Natl. Acad. Sci. USA 85, 7932-7936.
27. [27] Higgens, D.G. and Sharp, P.M. (1989) Fast and sensitive multiple sequence alignments on a microcomputer. Comp. Appl. Biosci. 5, 151-153.
28. [28] Haendler, B., Hofer-Warbinek, R. and Hofer, E. (1987) Complementary DNA for human T-cell cyclophilin. EMBO J. 6, 947-950.
29. [29] Walsh, C.T., Zydowsky, L.D. and McKeon, F.D. (1992) Cyclosporin A, the cyclophilin class of peptidylproly isomerases, and blockade of T cell signal transduction. J. Biol. Chem. 267, 13115-13118.
30. [30] Pfugl, G., Kallen, J., Schirmer, T., Jansonius, J.N., Zurini, G.M. and Walkinshaw, M.D. (1993) X-Ray structure of a decameric cyclophilin-cyclosporin crystal complex. Nature (Lond.) 361, 91-94.
31. [31] Lui, J., Albers, M.W., Chen, C.-M, Schreiber, S. and Walsh, C.T. (1990) Cloning, expression, and purification of human cyclophilin in Escherichia coli and assessment of the catalytic role of the cysteines by site-directed mutagenesis. Proc. Natl. Acad. Sci. USA 87, 2304-2308.
32. [32] Kofron, J.L., Kuzmic, P., Kishore, V., Colon-Bonilla, E. and Rich, D.H. (1991) Determination of kinetic constants for peptidyl prolyl cis-trans isomerases by an improved spectrophotometric assay. Biochemistry 30, 6127-6134.
33. [33] Liu, J. and Walsh, C.T. (1990) Peptidyl-prolyl cis-transisomerase from Escherichia coli: a periplasmic homolog of cyclophilin that is not inhibited by cyclosporin A. Proc. Natl. Acad. Sci. USA 87, 4028-4032.
34. [34] Stamnes, M.A., Shieh, B.H., Chuman, L., Harris, G.L. and Zuker, C.S. (1991) The cyclophilin homolog ninaA is a tissue-specific integral membrane protein required for the proper synthesis of a subset of Drosophila rhodopsins. Cell 65, 219-227.
35. [35] Kieffer, J.L., Thalhammer, T. and Handschumacher, R.E. (1992) Isolation and characterization of a 40-kDa cyclophilin-retated protein. J. Biol. Chem. 267, 5503-5507.