메뉴 건너뛰기




Volumn 4, Issue 1, 2006, Pages 45-57

Towards newer molecular targets for chronic diabetic complications

Author keywords

Advanced glycation end products; Aldose reductase; Diabetes; Endothelin; Fibronectin; Oxidative stress; Protein kinase C

Indexed keywords

ADVANCED GLYCATION END PRODUCT; ADVANCED GLYCATION END PRODUCT RECEPTOR; ALDEHYDE REDUCTASE; AMINOGUANIDINE; BOSENTAN; CAVEOLIN 1; ENDOTHELIN; ENDOTHELIN RECEPTOR ANTAGONIST; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INSULIN; LOSARTAN; MITOGEN ACTIVATED PROTEIN KINASE; MOLSIDOMINE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PLACEBO; POLYOL; PROTEIN KINASE; PROTEIN KINASE C; REACTIVE OXYGEN METABOLITE; RUBOXISTAURIN; VASCULOTROPIN; ANTIDIABETIC AGENT;

EID: 33644851090     PISSN: 15701611     EISSN: None     Source Type: Journal    
DOI: 10.2174/157016106775203081     Document Type: Review
Times cited : (52)

References (156)
  • 1
    • 0031897103 scopus 로고
    • Prevalence of diabetes, impaired fasting glucose, and impaired glucose tolerance in US adults: The Third National Health and Nutrition Examination Survey
    • Harris MI, Flegal KM, Cowie CC, Eberhardt MS, Goldstein DE, Little RR, et al. Prevalence of diabetes, impaired fasting glucose, and impaired glucose tolerance in US adults: the Third National Health and Nutrition Examination Survey. Diabetes Care 1998-1994; 21: 518-54.
    • (1994) Diabetes Care , vol.21 , pp. 518-554
    • Harris, M.I.1    Flegal, K.M.2    Cowie, C.C.3    Eberhardt, M.S.4    Goldstein, D.E.5    Little, R.R.6
  • 2
    • 0242284429 scopus 로고    scopus 로고
    • International Diabetes Federation, Second Edition. International Diabetes Federation; Brussells;
    • International Diabetes Federation. Diabetes Atlas, Second Edition. International Diabetes Federation; Brussells; 2003.
    • (2003) Diabetes Atlas
  • 3
    • 0027370108 scopus 로고
    • The effect of intensive treatment of diabetes on the development and progression of long-term complications in insulin-dependent diabetes mellitus
    • The Diabetes Control and Complications Trial Research Group
    • The Diabetes Control and Complications Trial Research Group. The effect of intensive treatment of diabetes on the development and progression of long-term complications in insulin-dependent diabetes mellitus. N Engl J Med 1993; 29: 977-86.
    • (1993) N Engl J Med , vol.29 , pp. 977-986
  • 4
    • 0032201492 scopus 로고    scopus 로고
    • Molecular mechanisms of diabetic complications
    • Aleksandrovski YA. Molecular mechanisms of diabetic complications. Biochemistry (Mosc) 1998, 63: 1249-1257.
    • (1998) Biochemistry (Mosc) , vol.63 , pp. 1249-1257
    • Aleksandrovski, Y.A.1
  • 5
    • 0035856980 scopus 로고    scopus 로고
    • Biochemistry and molecular cell biology of diabetic complications
    • Brownlee M. Biochemistry and molecular cell biology of diabetic complications. Nature 2000; 414: 813-20.
    • (2000) Nature , vol.414 , pp. 813-820
    • Brownlee, M.1
  • 6
    • 0037184495 scopus 로고    scopus 로고
    • Molecular understanding of hyperglycemia's adverse effects for diabetic complications
    • Sheetz MJ, King GL. Molecular understanding of hyperglycemia's adverse effects for diabetic complications. JAMA 2002; 288: 2579-88.
    • (2002) JAMA , vol.288 , pp. 2579-2588
    • Sheetz, M.J.1    King, G.L.2
  • 7
    • 0017739089 scopus 로고
    • Relationship of microvascular disease in diabetes to metabolic control
    • Engerman R, Bloodworth JM, Nelson S. Relationship of microvascular disease in diabetes to metabolic control. Diabetes 1985; 26: 760-9.
    • (1985) Diabetes , vol.26 , pp. 760-769
    • Engerman, R.1    Bloodworth, J.M.2    Nelson, S.3
  • 8
    • 0347364828 scopus 로고    scopus 로고
    • Features of macrovascular complications in type 2 diabetic patients
    • Strojek K. Features of macrovascular complications in type 2 diabetic patients. Acta Diabetol 2003; 40: S334-7.
    • (2003) Acta Diabetol , vol.40
    • Strojek, K.1
  • 9
    • 0038575321 scopus 로고    scopus 로고
    • Endothelins in chronic diabetic complications
    • Khan ZA, Chakrabarti S. Endothelins in chronic diabetic complications. Can J Physiol Pharmacol 2003; 81: 622-34.
    • (2003) Can J Physiol Pharmacol , vol.81 , pp. 622-634
    • Khan, Z.A.1    Chakrabarti, S.2
  • 10
    • 0036789361 scopus 로고    scopus 로고
    • Increased activity of endogenous endothelin in patients with type II diabetes mellitus
    • Cardillo C, Campia U, Bryant MB, Panza JA. Increased activity of endogenous endothelin in patients with type II diabetes mellitus. Circulation 2002; 106: 1783-7.
    • (2002) Circulation , vol.106 , pp. 1783-1787
    • Cardillo, C.1    Campia, U.2    Bryant, M.B.3    Panza, J.A.4
  • 11
    • 0026730090 scopus 로고
    • Endothelin-induced venoconstriction is unaffected by type 2-diabetes: In vivo effect of histamine on the endothelin action on veins
    • Blochl-Daum B, Vierhapper H, Eichler HG, Waldhausl W. Endothelin-induced venoconstriction is unaffected by type 2-diabetes: in vivo effect of histamine on the endothelin action on veins. Arch Int Pharmacodyn Ther 1992; 316: 90-6.
    • (1992) Arch Int Pharmacodyn Ther , vol.316 , pp. 90-96
    • Blochl-Daum, B.1    Vierhapper, H.2    Eichler, H.G.3    Waldhausl, W.4
  • 12
    • 0142122259 scopus 로고    scopus 로고
    • Changes of nailfold microcirculation in patients of type II diabetes mellitus with diabetic retinopathy
    • Yi Y, Baoyu W, Shenyuan Y, Liangxiang Z, Hanqing F, Yuantao L. Changes of nailfold microcirculation in patients of type II diabetes mellitus with diabetic retinopathy. Chin Med Sci J 1999; 14: 233-6.
    • (1999) Chin Med Sci J , vol.14 , pp. 233-236
    • Yi, Y.1    Baoyu, W.2    Shenyuan, Y.3    Liangxiang, Z.4    Hanqing, F.5    Yuantao, L.6
  • 13
    • 0036135178 scopus 로고    scopus 로고
    • Microvascular correlates of blood pressure, plasma glucose, and insulin resistance in health
    • Irving RJ, Walker BR, Noon JP, Watt GC, Webb DJ, Shore AC. Microvascular correlates of blood pressure, plasma glucose, and insulin resistance in health. Cardiovasc Res 2002; 53: 271-6.
    • (2002) Cardiovasc Res , vol.53 , pp. 271-276
    • Irving, R.J.1    Walker, B.R.2    Noon, J.P.3    Watt, G.C.4    Webb, D.J.5    Shore, A.C.6
  • 14
    • 0033458718 scopus 로고    scopus 로고
    • Vascular complications of diabetes mellitus
    • Yuan S, Liu Y, Zhu L. Vascular complications of diabetes mellitus. Clin Exp Pharmacol Physiol 1999; 26: 977-8.
    • (1999) Clin Exp Pharmacol Physiol , vol.26 , pp. 977-978
    • Yuan, S.1    Liu, Y.2    Zhu, L.3
  • 15
    • 0027640323 scopus 로고
    • Gastric mucosal blood flow and blood viscosity in patients with diabetes
    • Zhu L. Gastric mucosal blood flow and blood viscosity in patients with diabetes. Zhonghua Yi Xue Za Zhi 1993; 73: 476-8.
    • (1993) Zhonghua Yi Xue Za Zhi , vol.73 , pp. 476-478
    • Zhu, L.1
  • 17
    • 0035022781 scopus 로고    scopus 로고
    • Endothelium-dependent and independent vasodilation studies at normoglycaemia in type I diabetes mellitus with and without microalbuminuria
    • Dogra G, Rich L, Stanton K, Watts GF. Endothelium-dependent and independent vasodilation studies at normoglycaemia in type I diabetes mellitus with and without microalbuminuria. Diabetologia 2001; 44: 593-601.
    • (2001) Diabetologia , vol.44 , pp. 593-601
    • Dogra, G.1    Rich, L.2    Stanton, K.3    Watts, G.F.4
  • 18
    • 0029999087 scopus 로고    scopus 로고
    • Endothelium-dependent and -independent vasodilation of large arteries in normoalbuminuric insulin-dependent diabetes mellitus
    • Lambert J, Aarsen M, Donker AJ, Stehouwer CD. Endothelium-dependent and -independent vasodilation of large arteries in normoalbuminuric insulin-dependent diabetes mellitus. Arterioscler Thromb Vasc Biol 1996; 16: 705-11.
    • (1996) Arterioscler Thromb Vasc Biol , vol.16 , pp. 705-711
    • Lambert, J.1    Aarsen, M.2    Donker, A.J.3    Stehouwer, C.D.4
  • 19
    • 0032883593 scopus 로고    scopus 로고
    • Upregulation of endothelin A receptor sites in the rabbit diabetic kidney: Potential relevance to the early pathogenesis of diabetic nephropathy
    • Khan MA, Dashwood MR, Mumtaz FH, Thompson CS, Mikhailidis DP, Morgan RJ. Upregulation of endothelin A receptor sites in the rabbit diabetic kidney: potential relevance to the early pathogenesis of diabetic nephropathy. Nephron 1999; 83: 261-7.
    • (1999) Nephron , vol.83 , pp. 261-267
    • Khan, M.A.1    Dashwood, M.R.2    Mumtaz, F.H.3    Thompson, C.S.4    Mikhailidis, D.P.5    Morgan, R.J.6
  • 20
    • 0346724647 scopus 로고    scopus 로고
    • Down-regulation of nitric oxide synthase in the diabetic rabbit kidney: Potential relevance to the early pathogenesis of diabetic nephropathy
    • Mumtaz FH, Dashwood MR, Khan MA, Thompson CS, Mikhailidis DP, Morgan RJ. Down-regulation of nitric oxide synthase in the diabetic rabbit kidney: potential relevance to the early pathogenesis of diabetic nephropathy. Curr Med Res Opin 2004; 20: 1-6.
    • (2004) Curr Med Res Opin , vol.20 , pp. 1-6
    • Mumtaz, F.H.1    Dashwood, M.R.2    Khan, M.A.3    Thompson, C.S.4    Mikhailidis, D.P.5    Morgan, R.J.6
  • 21
    • 0029132915 scopus 로고
    • Circulating endothelin-1 reduces splanchnic and renal blood flow and splanchnic glucose production in humans
    • Ahlborg G, Weitzberg E, Lundberg JM. Circulating endothelin-1 reduces splanchnic and renal blood flow and splanchnic glucose production in humans. J Appl Physiol 1995; 79: 141-5.
    • (1995) J Appl Physiol , vol.79 , pp. 141-145
    • Ahlborg, G.1    Weitzberg, E.2    Lundberg, J.M.3
  • 22
    • 0029827820 scopus 로고    scopus 로고
    • Comparable potent coronary constrictor effects of endothelin-1 and big endothelin-1 in humans
    • Pernow J, Kaijser L, Lundberg JM, Ahlborg G. Comparable potent coronary constrictor effects of endothelin-1 and big endothelin-1 in humans. Circulation 1996; 94: 2077-82.
    • (1996) Circulation , vol.94 , pp. 2077-2082
    • Pernow, J.1    Kaijser, L.2    Lundberg, J.M.3    Ahlborg, G.4
  • 23
    • 0027970757 scopus 로고
    • Big ET-1 infusion in man causes renal ET-1 release, renal and splanchnic vasoconstriction, and increased mean arterial blood pressure
    • Ahlborg G, Ottosson-Seeberger A, Hemsen A, Lundberg JM. Big ET-1 infusion in man causes renal ET-1 release, renal and splanchnic vasoconstriction, and increased mean arterial blood pressure. Cardiovasc Res 1994; 28: 1559-63.
    • (1994) Cardiovasc Res , vol.28 , pp. 1559-1563
    • Ahlborg, G.1    Ottosson-Seeberger, A.2    Hemsen, A.3    Lundberg, J.M.4
  • 24
    • 0032868885 scopus 로고    scopus 로고
    • Diabetes-induced vascular dysfunction in the retina: Role of endothelins
    • Deng D, Evans T, Mukherjee K, Downey D, Chakrabarti S. Diabetes-induced vascular dysfunction in the retina: role of endothelins. Diabetologia 1999; 42: 1228-34.
    • (1999) Diabetologia , vol.42 , pp. 1228-1234
    • Deng, D.1    Evans, T.2    Mukherjee, K.3    Downey, D.4    Chakrabarti, S.5
  • 26
    • 0035377317 scopus 로고    scopus 로고
    • Peripheral nerve function is increasingly impaired during puberty in adolescents with type 1 diabetes
    • Riihimaa PH, Suominen K, Tolonen U, Jantti V, Knip M, Tapanainen P. Peripheral nerve function is increasingly impaired during puberty in adolescents with type 1 diabetes. Diabetes Care 2001; 24: 1087-92.
    • (2001) Diabetes Care , vol.24 , pp. 1087-1092
    • Riihimaa, P.H.1    Suominen, K.2    Tolonen, U.3    Jantti, V.4    Knip, M.5    Tapanainen, P.6
  • 27
    • 0025907341 scopus 로고
    • Role of height and glycosylated hemoglobin in abnormal nerve conduction in pediatric patients with type I diabetes mellitus after 4-9 yr of disease
    • Duck SC, Wei FF, Parke J, Swick HM. Role of height and glycosylated hemoglobin in abnormal nerve conduction in pediatric patients with type I diabetes mellitus after 4-9 yr of disease. Diabetes Care 1991; 14: 386-92.
    • (1991) Diabetes Care , vol.14 , pp. 386-392
    • Duck, S.C.1    Wei, F.F.2    Parke, J.3    Swick, H.M.4
  • 28
    • 0035195970 scopus 로고    scopus 로고
    • Vascular factors and metabolic interactions in the pathogenesis of diabetic neuropathy
    • Cameron NE, Eaton SE, Cotter MA, Tesfaye S. Vascular factors and metabolic interactions in the pathogenesis of diabetic neuropathy. Diabetologia 2001; 44: 1973-88.
    • (2001) Diabetologia , vol.44 , pp. 1973-1988
    • Cameron, N.E.1    Eaton, S.E.2    Cotter, M.A.3    Tesfaye, S.4
  • 29
    • 0028040725 scopus 로고
    • The relationship of vascular changes to metabolic factors in diabetes mellitus and their role in the development of peripheral nerve complications
    • Cameron NE, Cotter MA. The relationship of vascular changes to metabolic factors in diabetes mellitus and their role in the development of peripheral nerve complications. Diabetes Metab Rev 1994; 10: 189-224.
    • (1994) Diabetes Metab Rev , vol.10 , pp. 189-224
    • Cameron, N.E.1    Cotter, M.A.2
  • 30
    • 0032836681 scopus 로고    scopus 로고
    • Effects of antioxidants on nerve and vascular dysfunction in experimental diabetes
    • Cameron NE, Cotter MA. Effects of antioxidants on nerve and vascular dysfunction in experimental diabetes. Diabetes Res Clin Pract 1999; 45: 137-46.
    • (1999) Diabetes Res Clin Pract , vol.45 , pp. 137-146
    • Cameron, N.E.1    Cotter, M.A.2
  • 31
    • 0027960510 scopus 로고
    • The potential contribution of endothelin-1 to neurovascular abnormalities in streptozotocin diabetic rats
    • Cameron NE, Dines KC, Cotter MA. The potential contribution of endothelin-1 to neurovascular abnormalities in streptozotocin diabetic rats. Diabetologia 1994; 37: 1209-15.
    • (1994) Diabetologia , vol.37 , pp. 1209-1215
    • Cameron, N.E.1    Dines, K.C.2    Cotter, M.A.3
  • 32
    • 0029003206 scopus 로고
    • Effects of Endothelin receptor antagonism with bosentan on peripheral nerve function in experimental diabetes
    • Stevens EJ, Tomlinson DR. Effects of Endothelin receptor antagonism with bosentan on peripheral nerve function in experimental diabetes. Br J Pharmacol 1995; 115: 373-9.
    • (1995) Br J Pharmacol , vol.115 , pp. 373-379
    • Stevens, E.J.1    Tomlinson, D.R.2
  • 33
    • 0037820396 scopus 로고    scopus 로고
    • Microalbuminuria and hypertension with focus on type 1 and type 2 diabetes
    • Mogensen CE. Microalbuminuria and hypertension with focus on type 1 and type 2 diabetes. J Intern Med 2003; 254: 45-66.
    • (2003) J Intern Med , vol.254 , pp. 45-66
    • Mogensen, C.E.1
  • 34
    • 0028260381 scopus 로고
    • Systemic blood pressure and glomerular leakage with particular reference to diabetes and hypertension
    • Mogensen CE. Systemic blood pressure and glomerular leakage with particular reference to diabetes and hypertension. J Intern Med 1994; 235: 297-316.
    • (1994) J Intern Med , vol.235 , pp. 297-316
    • Mogensen, C.E.1
  • 35
    • 0037512352 scopus 로고    scopus 로고
    • Albuminuria and vascular damage - the vicious twins
    • Ritz E. Albuminuria and vascular damage - the vicious twins. N Engl J Med 2003; 348: 2349-52.
    • (2003) N Engl J Med , vol.348 , pp. 2349-2352
    • Ritz, E.1
  • 36
    • 0036316997 scopus 로고    scopus 로고
    • International Diabetic Nephropathy Study Group. The early natural history of nephropathy in type 1 diabetes: II. Early renal structural changes in type 1 diabetes
    • Drummond K, Mauer M. International Diabetic Nephropathy Study Group. The early natural history of nephropathy in type 1 diabetes: II. Early renal structural changes in type 1 diabetes. Diabetes 2002; 51: 1580-7.
    • (2002) Diabetes , vol.51 , pp. 1580-1587
    • Drummond, K.1    Mauer, M.2
  • 38
    • 0035079486 scopus 로고    scopus 로고
    • Time course of the antiproteinuric and renal haemodynamic responses to losartan in microalbuminuric IDDM
    • Buter H, Navis G, Dullaart RP, de Zeeuw D, de Jong PE. Time course of the antiproteinuric and renal haemodynamic responses to losartan in microalbuminuric IDDM. Nephrol Dial Transplant 2001; 16: 771-5.
    • (2001) Nephrol Dial Transplant , vol.16 , pp. 771-775
    • Buter, H.1    Navis, G.2    Dullaart, R.P.3    de Zeeuw, D.4    de Jong, P.E.5
  • 39
    • 0030692747 scopus 로고    scopus 로고
    • Elevated renal endothelin-1 clearance and mRNA levels associated with albuminuria and nephropathy in non-insulin dependent diabetes mellitus studies in obese fa/fa Zucker rats
    • Turner NC, Morgan PJ, Haynes AC, Vidgeon-Hart M, Toseland N, Clapham JC. Elevated renal endothelin-1 clearance and mRNA levels associated with albuminuria and nephropathy in non-insulin dependent diabetes mellitus studies in obese fa/fa Zucker rats. Clin Sci 1997; 93: 565-71.
    • (1997) Clin Sci , vol.93 , pp. 565-571
    • Turner, N.C.1    Morgan, P.J.2    Haynes, A.C.3    Vidgeon-Hart, M.4    Toseland, N.5    Clapham, J.C.6
  • 41
    • 6344280284 scopus 로고    scopus 로고
    • Diabetes is a vascular disease: The role of endothelial dysfunction in pathophysiology of cardiovascular disease in diabetes
    • Deedwania PC. Diabetes is a vascular disease: the role of endothelial dysfunction in pathophysiology of cardiovascular disease in diabetes. Cardiol Clin 2004; 22: 505-9.
    • (2004) Cardiol Clin , vol.22 , pp. 505-509
    • Deedwania, P.C.1
  • 42
    • 0034933340 scopus 로고    scopus 로고
    • Early cellular and molecular changes induced by diabetes in the retina
    • Lorenzi M, Gerhardinger C. Early cellular and molecular changes induced by diabetes in the retina. Diabetologia 2001; 44: 791-804.
    • (2001) Diabetologia , vol.44 , pp. 791-804
    • Lorenzi, M.1    Gerhardinger, C.2
  • 43
    • 0032879930 scopus 로고    scopus 로고
    • Diabetic retinopathy: Some cellular, molecular and therapeutic considerations
    • Archer DB. Diabetic retinopathy: some cellular, molecular and therapeutic considerations. Eye 1999; 13: 497-523.
    • (1999) Eye , vol.13 , pp. 497-523
    • Archer, D.B.1
  • 44
    • 0842327161 scopus 로고    scopus 로고
    • Three-year follow-up study of blood-retinal barrier and retinal thickness alterations in patients with type 2 diabetes mellitus and mild nonproliferative diabetic retinopathy
    • Lobo CL, Bernardes RC, Figueira JP, de Abreu JR, Cunha-Vaz JG. Three-year follow-up study of blood-retinal barrier and retinal thickness alterations in patients with type 2 diabetes mellitus and mild nonproliferative diabetic retinopathy. Arch Ophthalmol 2004; 122: 211-7.
    • (2004) Arch Ophthalmol , vol.122 , pp. 211-217
    • Lobo, C.L.1    Bernardes, R.C.2    Figueira, J.P.3    de Abreu, J.R.4    Cunha-Vaz, J.G.5
  • 45
    • 0031900927 scopus 로고    scopus 로고
    • Progression of retinopathy and alteration of the blood-retinal barrier in patients with type 2 diabetes: A 7-year prospective follow-up study
    • Cunha-Vaz J, Lobo C, Sousa JC, Oliveiros B, Leite E, de Abreu JR. Progression of retinopathy and alteration of the blood-retinal barrier in patients with type 2 diabetes: a 7-year prospective follow-up study. Graefes Arch Clin Exp Ophthalmol 1998; 236: 264-8.
    • (1998) Graefes Arch Clin Exp Ophthalmol , vol.236 , pp. 264-268
    • Cunha-Vaz, J.1    Lobo, C.2    Sousa, J.C.3    Oliveiros, B.4    Leite, E.5    de Abreu, J.R.6
  • 46
    • 0020545030 scopus 로고
    • Poor metabolic control, hypertension and microangiopathy independently increase the transcapillary escape rate of albumin in diabetes
    • O'Hare JA, Ferriss JB, Twomey B, O'Sullivan DJ. Poor metabolic control, hypertension and microangiopathy independently increase the transcapillary escape rate of albumin in diabetes. Diabetologia 1983; 25: 260-3.
    • (1983) Diabetologia , vol.25 , pp. 260-263
    • O'Hare, J.A.1    Ferriss, J.B.2    Twomey, B.3    O'Sullivan, D.J.4
  • 47
    • 0345767473 scopus 로고    scopus 로고
    • Growth factors in proliferative diabetic retinopathy
    • Khan ZA, Chakrabarti S. Growth factors in proliferative diabetic retinopathy. Exp Diabesity Res 2003; 4: 287-301.
    • (2003) Exp Diabesity Res , vol.4 , pp. 287-301
    • Khan, Z.A.1    Chakrabarti, S.2
  • 49
    • 0034112260 scopus 로고    scopus 로고
    • Endothelin receptor blockade prevents augmented extracellular matrix protein component mRNA expression and capillary basement membrane thickening in the retina of diabetic and galactose fed rats
    • Evans T, Deng DX, Chakrabarti S. Endothelin receptor blockade prevents augmented extracellular matrix protein component mRNA expression and capillary basement membrane thickening in the retina of diabetic and galactose fed rats. Diabetes 2000; 49: 662-6.
    • (2000) Diabetes , vol.49 , pp. 662-666
    • Evans, T.1    Deng, D.X.2    Chakrabarti, S.3
  • 50
    • 0030019991 scopus 로고    scopus 로고
    • Fibronectin overexpression in retinal microvessels of patients with diabetes
    • Roy S, Cagliero E, Lorenzi M. Fibronectin overexpression in retinal microvessels of patients with diabetes. Invest Ophthalmol Vis Sci 1996; 37: 258-66.
    • (1996) Invest Ophthalmol Vis Sci , vol.37 , pp. 258-266
    • Roy, S.1    Cagliero, E.2    Lorenzi, M.3
  • 51
    • 0038516909 scopus 로고    scopus 로고
    • Differential activation of NF-kappa B and AP-1 in increased fibronectin synthesis in target organs of diabetic complications
    • Chen S, Khan ZA, Cukiernik M, Chakrabarti S. Differential activation of NF-kappa B and AP-1 in increased fibronectin synthesis in target organs of diabetic complications. Am J Physiol Endocrinol Metab 2003; 284: E1089-97.
    • (2003) Am J Physiol Endocrinol Metab , vol.284
    • Chen, S.1    Khan, Z.A.2    Cukiernik, M.3    Chakrabarti, S.4
  • 53
    • 0037302999 scopus 로고    scopus 로고
    • High glucose-induced, endothelin-1 dependent fibronectin synthesis is mediated via NF-κB and AP-1
    • Chen S, Mukherjee S, Chakraborty C, Chakrabarti S. High glucose-induced, endothelin-1 dependent fibronectin synthesis is mediated via NF-κB and AP-1. Am J Physiol Cell Physiol 2003; 284: C263-72.
    • (2003) Am J Physiol Cell Physiol , vol.284
    • Chen, S.1    Mukherjee, S.2    Chakraborty, C.3    Chakrabarti, S.4
  • 55
    • 8344248674 scopus 로고    scopus 로고
    • Extracellular signal-regulated kinase (ERK) in glucose-induced and endothelinmediated fibronectin synthesis
    • Xin X, Khan ZA, Chen S, Chakrabarti S. Extracellular signal-regulated kinase (ERK) in glucose-induced and endothelinmediated fibronectin synthesis. Lab Invest 2004; 84: 1451-9.
    • (2004) Lab Invest , vol.84 , pp. 1451-1459
    • Xin, X.1    Khan, Z.A.2    Chen, S.3    Chakrabarti, S.4
  • 56
    • 0033662740 scopus 로고    scopus 로고
    • Extracellular signal-regulated kinase mediates stimulation of TGF-beta1 and matrix by high glucose in mesangial cells
    • Isono M, Cruz MC, Chen S, Hong SW, Ziyadeh FN. Extracellular signal-regulated kinase mediates stimulation of TGF-beta1 and matrix by high glucose in mesangial cells. J Am Soc Nephrol 2000; 11: 2222-30.
    • (2000) J Am Soc Nephrol , vol.11 , pp. 2222-2230
    • Isono, M.1    Cruz, M.C.2    Chen, S.3    Hong, S.W.4    Ziyadeh, F.N.5
  • 57
    • 0033741375 scopus 로고    scopus 로고
    • Changes in diabetic retinal matrix protein mRNA levels in a common transgenic mouse strain
    • Nishikawa T, Giardino I, Edelstein D, Brownlee M. Changes in diabetic retinal matrix protein mRNA levels in a common transgenic mouse strain. Curr Eye Res 2000; 21: 581-7.
    • (2000) Curr Eye Res , vol.21 , pp. 581-587
    • Nishikawa, T.1    Giardino, I.2    Edelstein, D.3    Brownlee, M.4
  • 60
    • 0023913225 scopus 로고
    • The involvement of aldose reductase in diabetic complications
    • Kinoshita JH, Nishimura C. The involvement of aldose reductase in diabetic complications. Diabetes Metab Rev 1988; 4: 323-37.
    • (1988) Diabetes Metab Rev , vol.4 , pp. 323-337
    • Kinoshita, J.H.1    Nishimura, C.2
  • 61
    • 0031920049 scopus 로고    scopus 로고
    • Aldose reductase in glucose toxicity: A potential target for the prevention of diabetic complications
    • Yabe-Nishimura C. Aldose reductase in glucose toxicity: a potential target for the prevention of diabetic complications. Pharmacol Rev 1998; 50: 21-33.
    • (1998) Pharmacol Rev , vol.50 , pp. 21-33
    • Yabe-Nishimura, C.1
  • 62
    • 0023275571 scopus 로고
    • Role of sorbitol accumulation and myo-inositol depletion in paranodal swelling of large myelinated nerve fibers in the insulin-deficient spontaneously diabetic bio-breeding rat. Reversal by insulin replacement, an aldose reductase inhibitor, and myo-inositol
    • Greene DA, Chakrabarti S, Lattimer SA, Sima AA. Role of sorbitol accumulation and myo-inositol depletion in paranodal swelling of large myelinated nerve fibers in the insulin-deficient spontaneously diabetic bio-breeding rat. Reversal by insulin replacement, an aldose reductase inhibitor, and myo-inositol. J Clin Invest 1987; 79: 1479-85.
    • (1987) J Clin Invest , vol.79 , pp. 1479-1485
    • Greene, D.A.1    Chakrabarti, S.2    Lattimer, S.A.3    Sima, A.A.4
  • 63
    • 0026508699 scopus 로고
    • The effect of myo-inositol treatment on basement membrane thickening in the BB/W-rat retina
    • Chakrabarti S, Sima AA. The effect of myo-inositol treatment on basement membrane thickening in the BB/W-rat retina. Diabetes Res Clin Pract 1992; 16: 13-7.
    • (1992) Diabetes Res Clin Pract , vol.16 , pp. 13-17
    • Chakrabarti, S.1    Sima, A.A.2
  • 64
    • 34249053780 scopus 로고    scopus 로고
    • Greene DA, Stevens MJ. In: Ed LeRoith D, Taylor S, Olefsky J. The sorbitol-osmotic and sorbitol-redox hypotheses. In: Diabetes Mellitus. Philadelphia, Lippincott-Raven Publishers. 1996; 801-9.
    • Greene DA, Stevens MJ. In: Ed LeRoith D, Taylor S, Olefsky J. The sorbitol-osmotic and sorbitol-redox hypotheses. In: Diabetes Mellitus. Philadelphia, Lippincott-Raven Publishers. 1996; 801-9.
  • 65
    • 0027318772 scopus 로고
    • Perspectives in Diabetes. Hyperglycemic pseudohypoxia and diabetic complications
    • Williamson JR, Chang K, Frangos M, Hasan KS, Ido Y, Kawamura T, et al. Perspectives in Diabetes. Hyperglycemic pseudohypoxia and diabetic complications. Diabetes 1993; 42: 801-13.
    • (1993) Diabetes , vol.42 , pp. 801-813
    • Williamson, J.R.1    Chang, K.2    Frangos, M.3    Hasan, K.S.4    Ido, Y.5    Kawamura, T.6
  • 66
    • 33750868990 scopus 로고    scopus 로고
    • Aldose reductase inhibition improves altered glucose metabolism of isolated diabetic rat hearts
    • Trueblood N, Ramasamy R. Aldose reductase inhibition improves altered glucose metabolism of isolated diabetic rat hearts. Am J Physiol 1998; 275: H75-83.
    • (1998) Am J Physiol , vol.275
    • Trueblood, N.1    Ramasamy, R.2
  • 67
    • 10244222747 scopus 로고    scopus 로고
    • Aldose reductase gene polymorphisms and susceptibility to microvascular complications in Type 2 diabetes
    • Sivenius K, Niskanen L, Voutilainen-Kaunisto R, Laakso M, Uusitupa M. Aldose reductase gene polymorphisms and susceptibility to microvascular complications in Type 2 diabetes. Diabet Med 2004; 21: 1325-33.
    • (2004) Diabet Med , vol.21 , pp. 1325-1333
    • Sivenius, K.1    Niskanen, L.2    Voutilainen-Kaunisto, R.3    Laakso, M.4    Uusitupa, M.5
  • 68
    • 0042023720 scopus 로고    scopus 로고
    • Phenotypic heterogeneity and associations of two aldose reductase gene polymorphisms with nephropathy and retinopathy in type 2 diabetes
    • Wang Y, Ng MC, Lee SC, So WY, Tong PC, Cockram CS, et al. Phenotypic heterogeneity and associations of two aldose reductase gene polymorphisms with nephropathy and retinopathy in type 2 diabetes. Diabetes Care 2003; 26: 2410-5.
    • (2003) Diabetes Care , vol.26 , pp. 2410-2415
    • Wang, Y.1    Ng, M.C.2    Lee, S.C.3    So, W.Y.4    Tong, P.C.5    Cockram, C.S.6
  • 69
    • 0041809017 scopus 로고    scopus 로고
    • Polymorphisms of the aldose reductase gene and susceptibility to diabetic microvascular complications
    • Demaine AG. Polymorphisms of the aldose reductase gene and susceptibility to diabetic microvascular complications. Curr Med Chem 2003; 10: 1389-98.
    • (2003) Curr Med Chem , vol.10 , pp. 1389-1398
    • Demaine, A.G.1
  • 70
    • 0032959371 scopus 로고    scopus 로고
    • Diabetes complications and their potential prevention: Aldose reductase inhibition and other approaches
    • Costantino L, Rastelli G, Vianello P, Cignarella G, Barlocco D. Diabetes complications and their potential prevention: aldose reductase inhibition and other approaches. Med Res Rev 1999; 19: 3-23.
    • (1999) Med Res Rev , vol.19 , pp. 3-23
    • Costantino, L.1    Rastelli, G.2    Vianello, P.3    Cignarella, G.4    Barlocco, D.5
  • 71
    • 0027143826 scopus 로고
    • Capillary basement membrane in retina, kidney, and muscle of diabetic dogs and galactosemic dogs and its response to 5 years aldose reductase inhibition
    • Engerman RL, Kern TS, Garment MB. Capillary basement membrane in retina, kidney, and muscle of diabetic dogs and galactosemic dogs and its response to 5 years aldose reductase inhibition. J Diabetes Complications 1993; 7: 241-5.
    • (1993) J Diabetes Complications , vol.7 , pp. 241-245
    • Engerman, R.L.1    Kern, T.S.2    Garment, M.B.3
  • 72
    • 0025073693 scopus 로고
    • A randomized trial of sorbinil, an aldose reductase inhibitor, in diabetic retinopathy
    • Sorbinil Retinopathy Trial Research Group
    • Sorbinil Retinopathy Trial Research Group. A randomized trial of sorbinil, an aldose reductase inhibitor, in diabetic retinopathy. Arch Ophthalmol 1990; 108: 1234-44.
    • (1990) Arch Ophthalmol , vol.108 , pp. 1234-1244
  • 73
    • 0042309876 scopus 로고    scopus 로고
    • Recent studies of aldose reductase enzyme inhibition for diabetic complications
    • Suzen S, Buyukbingol E. Recent studies of aldose reductase enzyme inhibition for diabetic complications. Curr Med Chem 2003; 10: 1329-52.
    • (2003) Curr Med Chem , vol.10 , pp. 1329-1352
    • Suzen, S.1    Buyukbingol, E.2
  • 74
    • 0026451081 scopus 로고
    • Intracellular signaling by hydrolysis of phospholipids and activation of protein kinase C
    • Nishizuka Y. Intracellular signaling by hydrolysis of phospholipids and activation of protein kinase C. Science 1992; 258: 607-14.
    • (1992) Science , vol.258 , pp. 607-614
    • Nishizuka, Y.1
  • 75
    • 0031860340 scopus 로고    scopus 로고
    • Protein kinase C activation and the development of diabetic complications
    • Koya D, King GL. Protein kinase C activation and the development of diabetic complications. Diabetes 1998; 47: 859-66.
    • (1998) Diabetes , vol.47 , pp. 859-866
    • Koya, D.1    King, G.L.2
  • 76
    • 33751269676 scopus 로고    scopus 로고
    • Interaction of PKC and NOS in signal transduction of microvascular hyperpermeability
    • Huang Q, Yuan Y. Interaction of PKC and NOS in signal transduction of microvascular hyperpermeability. Am J Physiol 1997; 273: H2442- 51.
    • (1997) Am J Physiol , vol.273
    • Huang, Q.1    Yuan, Y.2
  • 77
    • 0038642030 scopus 로고    scopus 로고
    • Effects of protein kinase C inhibition and activation on proliferation and apoptosis of bovine retinal pericytes
    • Pomero F, Allione A, Beltramo E, Buttiglieri S, D'Alu F, Ponte E, et al. Effects of protein kinase C inhibition and activation on proliferation and apoptosis of bovine retinal pericytes. Diabetologia 2003; 46: 416-9.
    • (2003) Diabetologia , vol.46 , pp. 416-419
    • Pomero, F.1    Allione, A.2    Beltramo, E.3    Buttiglieri, S.4    D'Alu, F.5    Ponte, E.6
  • 78
    • 0033949316 scopus 로고    scopus 로고
    • Induction of endothelin-1 expression by glucose: An effect of protein kinase C activation
    • Park JY, Takahara N, Gabriele A, Chou E, Naruse K, Suzuma K, et al. Induction of endothelin-1 expression by glucose: an effect of protein kinase C activation. Diabetes 2000; 49: 1239-48.
    • (2000) Diabetes , vol.49 , pp. 1239-1248
    • Park, J.Y.1    Takahara, N.2    Gabriele, A.3    Chou, E.4    Naruse, K.5    Suzuma, K.6
  • 79
    • 0034852862 scopus 로고    scopus 로고
    • Protein kinase C activation: Isozyme-specific effects on metabolism and cardiovascular complications in diabetes
    • Idris I, Gray S, Donnelly R. Protein kinase C activation: isozyme-specific effects on metabolism and cardiovascular complications in diabetes. Diabetologia 2001; 44: 659-73.
    • (2001) Diabetologia , vol.44 , pp. 659-673
    • Idris, I.1    Gray, S.2    Donnelly, R.3
  • 80
    • 0026489335 scopus 로고
    • Preferential elevation of protein kinase C isoform beta II and diacylglycerol levels in the aorta and heart of diabetic rats: Differential reversibility to glycemic control by islet cell transplantation
    • Inoguchi T, Battan R, Handler E, Sportsman JR, Heath W, King GL. Preferential elevation of protein kinase C isoform beta II and diacylglycerol levels in the aorta and heart of diabetic rats: differential reversibility to glycemic control by islet cell transplantation. Proc Natl Acad Sci USA 1992; 89: 11059-63.
    • (1992) Proc Natl Acad Sci USA , vol.89 , pp. 11059-11063
    • Inoguchi, T.1    Battan, R.2    Handler, E.3    Sportsman, J.R.4    Heath, W.5    King, G.L.6
  • 81
    • 0032139683 scopus 로고    scopus 로고
    • Glucose-dependent decreased DNA synthesis in bovine retinal endothelial cells is mediated by protein kinase C iota
    • Knott RM, Keenan FE, Muckersie E, Robertson M, Forrester JV. Glucose-dependent decreased DNA synthesis in bovine retinal endothelial cells is mediated by protein kinase C iota. Biochem Soc Trans 1998; 26: S260.
    • (1998) Biochem Soc Trans , vol.26
    • Knott, R.M.1    Keenan, F.E.2    Muckersie, E.3    Robertson, M.4    Forrester, J.V.5
  • 82
    • 13344293711 scopus 로고    scopus 로고
    • Amelioration of vascular dysfunctions in diabetic rats by an oral PKC beta inhibitor
    • Ishii H, Jirousek MR, Koya D, Takagi C, Xia P, Clermont A, et al. Amelioration of vascular dysfunctions in diabetic rats by an oral PKC beta inhibitor. Science 1996; 272: 728-31.
    • (1996) Science , vol.272 , pp. 728-731
    • Ishii, H.1    Jirousek, M.R.2    Koya, D.3    Takagi, C.4    Xia, P.5    Clermont, A.6
  • 83
    • 0031891448 scopus 로고    scopus 로고
    • Abnormalities of retinal metabolism in diabetes or experimental galactosemia: V. Relationship between protein kinase C and ATPases
    • Kowluru RA, Jirousek MR, Stramm L, Farid N, Engerman RL, Kern TS. Abnormalities of retinal metabolism in diabetes or experimental galactosemia: V. Relationship between protein kinase C and ATPases. Diabetes 1998; 47: 464-9.
    • (1998) Diabetes , vol.47 , pp. 464-469
    • Kowluru, R.A.1    Jirousek, M.R.2    Stramm, L.3    Farid, N.4    Engerman, R.L.5    Kern, T.S.6
  • 84
    • 0031964664 scopus 로고    scopus 로고
    • Inhibition of intraocular neovascularization caused by retinal ischemia in pigs by PKCbeta inhibition with LY333531
    • Danis RP, Bingaman DP, Jirousek M, Yang Y. Inhibition of intraocular neovascularization caused by retinal ischemia in pigs by PKCbeta inhibition with LY333531. Invest Ophthalmol Vis Sci 1998; 39: 171-9.
    • (1998) Invest Ophthalmol Vis Sci , vol.39 , pp. 171-179
    • Danis, R.P.1    Bingaman, D.P.2    Jirousek, M.3    Yang, Y.4
  • 85
    • 0012387019 scopus 로고    scopus 로고
    • Pharmacokinetics and safety of multiple oral doses of LY333531, a PKC beta inhibitor, in healthy subjects
    • Demolle D, de Suray JM, Onkelinx C. Pharmacokinetics and safety of multiple oral doses of LY333531, a PKC beta inhibitor, in healthy subjects. Clin Pharm Ther 1999; 65: 189.
    • (1999) Clin Pharm Ther , vol.65 , pp. 189
    • Demolle, D.1    de Suray, J.M.2    Onkelinx, C.3
  • 86
    • 0012425174 scopus 로고    scopus 로고
    • LY333531 single escalating oral dose study in healthy volunteers
    • Demolle D, de Suray JM, Vandenhende F. LY333531 single escalating oral dose study in healthy volunteers. Diabetologia 1998; 41: A354.
    • (1998) Diabetologia , vol.41
    • Demolle, D.1    de Suray, J.M.2    Vandenhende, F.3
  • 87
    • 0000001975 scopus 로고    scopus 로고
    • Protein kinase C beta selective inhibitor LY333531 ameliorates abnormal retinal haemodynamics in patients with diabetes
    • Aiello LP, Bursell S, Devries T. Protein kinase C beta selective inhibitor LY333531 ameliorates abnormal retinal haemodynamics in patients with diabetes. Diabetes 1999; 48: A19.
    • (1999) Diabetes , vol.48
    • Aiello, L.P.1    Bursell, S.2    Devries, T.3
  • 88
    • 0142121886 scopus 로고    scopus 로고
    • Initial results of the Protein Kinase C b Inhibitor Diabetic Retinopathy Study (PKC-DRS)
    • Milton R, Aiello L, Davis M, Sheetz M, Arora V, Vignati L. Initial results of the Protein Kinase C b Inhibitor Diabetic Retinopathy Study (PKC-DRS). Diabetes 2003; 52: A127.
    • (2003) Diabetes , vol.52
    • Milton, R.1    Aiello, L.2    Davis, M.3    Sheetz, M.4    Arora, V.5    Vignati, L.6
  • 89
    • 0030963670 scopus 로고    scopus 로고
    • Recent progress in advanced glycation end products and diabetic complications
    • Vlassara H. Recent progress in advanced glycation end products and diabetic complications. Diabetes 1997; 46: S19-25.
    • (1997) Diabetes , vol.46
    • Vlassara, H.1
  • 90
    • 0035668462 scopus 로고    scopus 로고
    • The AGE-receptor in the pathogenesis of diabetic complications
    • Vlassara H. The AGE-receptor in the pathogenesis of diabetic complications. Diabetes Metab Res Rev 2001; 17: 436-43.
    • (2001) Diabetes Metab Res Rev , vol.17 , pp. 436-443
    • Vlassara, H.1
  • 91
    • 0032029363 scopus 로고    scopus 로고
    • AGEs and their interaction with AGE-receptors in vascular disease and diabetes mellitus. I. The AGE concept
    • Bierhaus A, Hofmann MA, Ziegler R, Nawroth PP. AGEs and their interaction with AGE-receptors in vascular disease and diabetes mellitus. I. The AGE concept. Cardiovasc Res 1998; 37: 586-600.
    • (1998) Cardiovasc Res , vol.37 , pp. 586-600
    • Bierhaus, A.1    Hofmann, M.A.2    Ziegler, R.3    Nawroth, P.P.4
  • 92
    • 0028917712 scopus 로고
    • Significance of fructose-induced protein oxidation and formation of advanced glycation end product
    • Takagi Y, Kashiwagi A, Tanaka Y, Asahian T, Kikkawa R, Shigeta Y. Significance of fructose-induced protein oxidation and formation of advanced glycation end product. J Diabetes Comp 1995; 9: 89-91.
    • (1995) J Diabetes Comp , vol.9 , pp. 89-91
    • Takagi, Y.1    Kashiwagi, A.2    Tanaka, Y.3    Asahian, T.4    Kikkawa, R.5    Shigeta, Y.6
  • 93
    • 0028934990 scopus 로고
    • Mechanism of protein modification by glyoxal and glycolaldehyde, reactive intermediates of the Maillard reaction
    • Glomb MA, Monnier VM. Mechanism of protein modification by glyoxal and glycolaldehyde, reactive intermediates of the Maillard reaction. J Biol Chem 1995; 270: 10017-26.
    • (1995) J Biol Chem , vol.270 , pp. 10017-10026
    • Glomb, M.A.1    Monnier, V.M.2
  • 94
    • 0033599504 scopus 로고    scopus 로고
    • Characterization of the advanced glycation end-product receptor complex in human vascular endothelial cells
    • Stitt AW, He C, Vlassara H. Characterization of the advanced glycation end-product receptor complex in human vascular endothelial cells. Biochem Biophys Res Commun 1999; 256: 549-56.
    • (1999) Biochem Biophys Res Commun , vol.256 , pp. 549-556
    • Stitt, A.W.1    He, C.2    Vlassara, H.3
  • 95
    • 0031019612 scopus 로고    scopus 로고
    • Advanced glycation end products (AGEs) co-localize with AGE receptors in the retinal vasculature of diabetic and of AGE-infused rats
    • Stitt AW, Li YM, Gardiner TA, Bucala R, Archer DB, Vlassara H. Advanced glycation end products (AGEs) co-localize with AGE receptors in the retinal vasculature of diabetic and of AGE-infused rats. Am J Pathol 1997; 150: 523-31.
    • (1997) Am J Pathol , vol.150 , pp. 523-531
    • Stitt, A.W.1    Li, Y.M.2    Gardiner, T.A.3    Bucala, R.4    Archer, D.B.5    Vlassara, H.6
  • 98
    • 0035409354 scopus 로고    scopus 로고
    • Pharmacological inhibition of diabetic retinopathy: Aminoguanidine and aspirin
    • Kern TS, Engerman RL. Pharmacological inhibition of diabetic retinopathy: aminoguanidine and aspirin. Diabetes 2001; 50: 1636-42.
    • (2001) Diabetes , vol.50 , pp. 1636-1642
    • Kern, T.S.1    Engerman, R.L.2
  • 100
    • 0024468052 scopus 로고
    • Endothelial receptor mediated binding of glucose modified albumin is associated with increased monolayer permeability and modulation of cell surface coagulant properties
    • Esposito C, Gerlach H, Brett J. Endothelial receptor mediated binding of glucose modified albumin is associated with increased monolayer permeability and modulation of cell surface coagulant properties. J Exp Med 1992; 170: 1387-97.
    • (1992) J Exp Med , vol.170 , pp. 1387-1397
    • Esposito, C.1    Gerlach, H.2    Brett, J.3
  • 101
    • 17144457576 scopus 로고    scopus 로고
    • Advanced glycation end products-driven angiogenesis in vitro. Induction of the growth and tube formation of human microvascular endothelial cells through autocrine vascular endothelial growth factor
    • Yamagishi S, Yonekura H, Yamamoto Y, Katsuno K, Sato F, Mita I, et al. Advanced glycation end products-driven angiogenesis in vitro. Induction of the growth and tube formation of human microvascular endothelial cells through autocrine vascular endothelial growth factor. J Biol Chem 1997; 272: 8723-30.
    • (1997) J Biol Chem , vol.272 , pp. 8723-8730
    • Yamagishi, S.1    Yonekura, H.2    Yamamoto, Y.3    Katsuno, K.4    Sato, F.5    Mita, I.6
  • 102
    • 0035172601 scopus 로고    scopus 로고
    • Therapeutic potential of AGE inhibitors and breakers of AGE protein cross-links
    • Vasan S, Foiles PG, Founds HW. Therapeutic potential of AGE inhibitors and breakers of AGE protein cross-links. Expert Opin Investig Drugs 2001; 10: 1977-87.
    • (2001) Expert Opin Investig Drugs , vol.10 , pp. 1977-1987
    • Vasan, S.1    Foiles, P.G.2    Founds, H.W.3
  • 103
    • 0037263160 scopus 로고    scopus 로고
    • Exogenous advanced glycosylation end products induce diabetes-like vascular dysfunction in normal rats: A factor in diabetic retinopathy
    • Xu X, Li Z, Luo D. Exogenous advanced glycosylation end products induce diabetes-like vascular dysfunction in normal rats: a factor in diabetic retinopathy. Graefes Arch Clin Exp Ophthalmol 2003; 241: 56-62.
    • (2003) Graefes Arch Clin Exp Ophthalmol , vol.241 , pp. 56-62
    • Xu, X.1    Li, Z.2    Luo, D.3
  • 106
    • 8644267972 scopus 로고    scopus 로고
    • Hyperglycemia-induced oxidative stress in diabetic complications
    • King GL, Loeken MR. Hyperglycemia-induced oxidative stress in diabetic complications. Histochem Cell Biol 2004; 122: 333-8.
    • (2004) Histochem Cell Biol , vol.122 , pp. 333-338
    • King, G.L.1    Loeken, M.R.2
  • 107
    • 0344837347 scopus 로고    scopus 로고
    • Benfotiamine blocks three major pathways of hyperglycemic damage and prevents experimental diabetic retinopathy
    • Hammes HP, Du X, Edelstein D, Taguchi T, Matsumura T, Ju Q, et al. Benfotiamine blocks three major pathways of hyperglycemic damage and prevents experimental diabetic retinopathy. Nat Med 2003; 9: 294-9.
    • (2003) Nat Med , vol.9 , pp. 294-299
    • Hammes, H.P.1    Du, X.2    Edelstein, D.3    Taguchi, T.4    Matsumura, T.5    Ju, Q.6
  • 108
    • 0027279232 scopus 로고
    • Diabetes mellitus and free radicals. Free radicals, transition metals and oxidative stress in the aetiology of diabetes mellitus and complications
    • Wolff SP. Diabetes mellitus and free radicals. Free radicals, transition metals and oxidative stress in the aetiology of diabetes mellitus and complications. Br Med Bull 1993; 49: 642-52.
    • (1993) Br Med Bull , vol.49 , pp. 642-652
    • Wolff, S.P.1
  • 109
    • 0034643340 scopus 로고    scopus 로고
    • Normalizing mitochondrial superoxide production blocks three pathways of hyperglycaemic damage
    • Nishikawa T, Edelstein D, Du XL, Yamagishi S, Matsumura T, Kaneda Y, et al. Normalizing mitochondrial superoxide production blocks three pathways of hyperglycaemic damage. Nature 2000; 404: 787-90.
    • (2000) Nature , vol.404 , pp. 787-790
    • Nishikawa, T.1    Edelstein, D.2    Du, X.L.3    Yamagishi, S.4    Matsumura, T.5    Kaneda, Y.6
  • 110
    • 0034710891 scopus 로고    scopus 로고
    • Hyperglycemia-induced mitochondrial superoxide overproduction activates the hexosamine pathway and induces plasminogen activator inhibitor-1 expression by increasing Sp1 glycosylation
    • Du XL, Edelstein D, Rossetti L, Fantus IG, Goldberg H, Ziyadeh F, et al. Hyperglycemia-induced mitochondrial superoxide overproduction activates the hexosamine pathway and induces plasminogen activator inhibitor-1 expression by increasing Sp1 glycosylation. Proc Natl Acad Sci USA 2000; 97: 12222-6.
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 12222-12226
    • XL, D.1    Edelstein, D.2    Rossetti, L.3    Fantus, I.G.4    Goldberg, H.5    Ziyadeh, F.6
  • 111
    • 0031656261 scopus 로고    scopus 로고
    • Role of NADH/NADPH oxidase-derived H2 O2 in angiotensin II-induced vascular hypertrophy
    • Zafari AM, Ushio-Fukai M, Akers M, Shah A, Harison DG, Taylor WR, et al. Role of NADH/NADPH oxidase-derived H2 O2 in angiotensin II-induced vascular hypertrophy. Hypertension 1998; 32: 488-95.
    • (1998) Hypertension , vol.32 , pp. 488-495
    • Zafari, A.M.1    Ushio-Fukai, M.2    Akers, M.3    Shah, A.4    Harison, D.G.5    Taylor, W.R.6
  • 112
    • 0033586639 scopus 로고    scopus 로고
    • Increased NADH oxidase-mediated superoxide production in the early stages of atherosclerosis: Evidence for involvement of the reninangiotensin system
    • Warnholtz A, Nickening G, Schultz E. Increased NADH oxidase-mediated superoxide production in the early stages of atherosclerosis: evidence for involvement of the reninangiotensin system. Circulation 1999; 99: 2027-33.
    • (1999) Circulation , vol.99 , pp. 2027-2033
    • Warnholtz, A.1    Nickening, G.2    Schultz, E.3
  • 113
    • 0036020543 scopus 로고    scopus 로고
    • Modulating poly (ADP-ribose) polymerase activity: Potential for the prevention and therapy of pathogenic situations involving DNA damage and oxidative stress
    • Decker P, Muller S. Modulating poly (ADP-ribose) polymerase activity: potential for the prevention and therapy of pathogenic situations involving DNA damage and oxidative stress. Curr Pharm Biotechnol 2002; 3: 275-83.
    • (2002) Curr Pharm Biotechnol , vol.3 , pp. 275-283
    • Decker, P.1    Muller, S.2
  • 114
    • 12144279066 scopus 로고    scopus 로고
    • Aldose reductase inhibition counteracts oxidative-nitrosative stress and poly(ADP-ribose) polymerase activation in tissue sites for diabetes complications
    • Obrosova IG, Pacher P, Szabo C, Zsengeller Z, Hirooka H, Stevens MJ, et al. Aldose reductase inhibition counteracts oxidative-nitrosative stress and poly(ADP-ribose) polymerase activation in tissue sites for diabetes complications. Diabetes 2005; 54: 234-42.
    • (2005) Diabetes , vol.54 , pp. 234-242
    • Obrosova, I.G.1    Pacher, P.2    Szabo, C.3    Zsengeller, Z.4    Hirooka, H.5    Stevens, M.J.6
  • 115
    • 0034890040 scopus 로고    scopus 로고
    • Diabetic endothelial dysfunction: Role of reactive oxygen and nitrogen species production and poly(ADP-ribose) polymerase activation
    • Soriano FG, Virag L, Szabo C. Diabetic endothelial dysfunction: role of reactive oxygen and nitrogen species production and poly(ADP-ribose) polymerase activation. J Mol Med 2001; 79: 437-48.
    • (2001) J Mol Med , vol.79 , pp. 437-448
    • Soriano, F.G.1    Virag, L.2    Szabo, C.3
  • 116
    • 0035136240 scopus 로고    scopus 로고
    • Diabetic endothelial dysfunction: The role of poly(ADP-ribose) polymerase activation
    • Garcia Soriano F, Virag L, Jagtap P, Szabo E, Mabley JG, Liaudet L, et al. Diabetic endothelial dysfunction: the role of poly(ADP-ribose) polymerase activation. Nat Med 2001; 7: 108-13.
    • (2001) Nat Med , vol.7 , pp. 108-113
    • Garcia Soriano, F.1    Virag, L.2    Jagtap, P.3    Szabo, E.4    Mabley, J.G.5    Liaudet, L.6
  • 117
    • 0035851210 scopus 로고    scopus 로고
    • Rapid reversal of the diabetic endothelial dysfunction by pharmacological inhibition of poly(ADP-ribose) polymerase
    • Soriano FG, Pacher P, Mabley J, Liaudet L, Szabo C. Rapid reversal of the diabetic endothelial dysfunction by pharmacological inhibition of poly(ADP-ribose) polymerase. Circ Res 2001; 89: 684-91.
    • (2001) Circ Res , vol.89 , pp. 684-691
    • Soriano, F.G.1    Pacher, P.2    Mabley, J.3    Liaudet, L.4    Szabo, C.5
  • 119
    • 1842535231 scopus 로고    scopus 로고
    • Inducible nitric oxide synthase and vascular endothelial growth factor are colocalized in the retinas of human subjects with diabetes
    • Abu El-Asrar AM, Meersschaert A, Dralands L, Missotten L, Geboes K. Inducible nitric oxide synthase and vascular endothelial growth factor are colocalized in the retinas of human subjects with diabetes. Eye 2004; 18: 306-13.
    • (2004) Eye , vol.18 , pp. 306-313
    • Abu El-Asrar, A.M.1    Meersschaert, A.2    Dralands, L.3    Missotten, L.4    Geboes, K.5
  • 120
    • 0037153047 scopus 로고    scopus 로고
    • Endothelial function. From vascular biology to clinical applications
    • Behrendt D, Ganz P. Endothelial function. From vascular biology to clinical applications. Am J Cardiol 2002; 90: 40L-48L.
    • (2002) Am J Cardiol , vol.90
    • Behrendt, D.1    Ganz, P.2
  • 121
    • 0022456638 scopus 로고
    • Superoxide anions and hyperoxia inactivate endothelium-derived relaxing factor
    • Rubanyi GM, Vanhoutte PM. Superoxide anions and hyperoxia inactivate endothelium-derived relaxing factor. Am J Physiol 1986; 250: H822-7.
    • (1986) Am J Physiol , vol.250
    • Rubanyi, G.M.1    Vanhoutte, P.M.2
  • 122
    • 0027242030 scopus 로고
    • Hypercholesterolemia increases endothelial superoxide anion production
    • Ohara Y, Peterson TE, Harrison DG. Hypercholesterolemia increases endothelial superoxide anion production. J Clin Invest 1993; 91: 2546-51.
    • (1993) J Clin Invest , vol.91 , pp. 2546-2551
    • Ohara, Y.1    Peterson, T.E.2    Harrison, D.G.3
  • 124
    • 0026567377 scopus 로고
    • Human dermal microvascular endothelial but not human umbilical vein endothelial cells express CD36 in vivo and in vitro
    • Swerlick RA, Lee KH, Wick TM, Lawley TJ. Human dermal microvascular endothelial but not human umbilical vein endothelial cells express CD36 in vivo and in vitro. J Immunol 1992; 148: 78-83.
    • (1992) J Immunol , vol.148 , pp. 78-83
    • Swerlick, R.A.1    Lee, K.H.2    Wick, T.M.3    Lawley, T.J.4
  • 125
    • 34249039188 scopus 로고    scopus 로고
    • Endothelin-mediated upregulation of CD36 in target organs of chronic diabetic complications
    • Khan ZA, Fukuda G, Cukiernik M, Chakrabarti S. Endothelin-mediated upregulation of CD36 in target organs of chronic diabetic complications. Can J Diabetes 2003; 27: A248.
    • (2003) Can J Diabetes , vol.27
    • Khan, Z.A.1    Fukuda, G.2    Cukiernik, M.3    Chakrabarti, S.4
  • 126
    • 0011172276 scopus 로고
    • A role for endothelial cell lipoxygenase in the oxidative modification of low density lipoprotein
    • Parthasarathy S, Wieland E, Steinberg D. A role for endothelial cell lipoxygenase in the oxidative modification of low density lipoprotein. Proc Natl Acad Sci USA 1989; 86: 1046-50.
    • (1989) Proc Natl Acad Sci USA , vol.86 , pp. 1046-1050
    • Parthasarathy, S.1    Wieland, E.2    Steinberg, D.3
  • 127
    • 0033973712 scopus 로고    scopus 로고
    • The heme synthesis and degradation pathways: Role in oxidant sensitivity. Heme oxygenase has both pro-and antioxidant properties
    • Ryter SW, Tyrrell RM. The heme synthesis and degradation pathways: role in oxidant sensitivity. Heme oxygenase has both pro-and antioxidant properties. Free Radic Biol Med 2000; 28: 289-309.
    • (2000) Free Radic Biol Med , vol.28 , pp. 289-309
    • Ryter, S.W.1    Tyrrell, R.M.2
  • 129
    • 0029818865 scopus 로고    scopus 로고
    • Abnormalities of retinal metabolism in diabetes or experimental galactosemia. III. Effects of antioxidants
    • Kowluru RA, Kern TS, Engerman RL, Armstrong D. Abnormalities of retinal metabolism in diabetes or experimental galactosemia. III. Effects of antioxidants. Diabetes 1997; 45: 1233-7.
    • (1997) Diabetes , vol.45 , pp. 1233-1237
    • Kowluru, R.A.1    Kern, T.S.2    Engerman, R.L.3    Armstrong, D.4
  • 130
    • 0033758785 scopus 로고    scopus 로고
    • Why is glycated LDL more sensitive to oxidation than native LDL? A comparative study
    • Sobal G, Menzel J, Sinzinger H. Why is glycated LDL more sensitive to oxidation than native LDL? A comparative study. Prostaglandins Leukot Essent Fatty Acids 2000; 63: 177-86.
    • (2000) Prostaglandins Leukot Essent Fatty Acids , vol.63 , pp. 177-186
    • Sobal, G.1    Menzel, J.2    Sinzinger, H.3
  • 131
    • 0031895554 scopus 로고    scopus 로고
    • Glucose-induced oxidative stress in vascular contractile cells: Comparison of aortic smooth muscle cells and retinal pericytes
    • Sharpe PC, Liu WH, Yue KK, McMaster D, Catherwood MA, McGinty AM, et al. Glucose-induced oxidative stress in vascular contractile cells: comparison of aortic smooth muscle cells and retinal pericytes. Diabetes 1998; 47: 801-9.
    • (1998) Diabetes , vol.47 , pp. 801-809
    • Sharpe, P.C.1    Liu, W.H.2    Yue, K.K.3    McMaster, D.4    Catherwood, M.A.5    McGinty, A.M.6
  • 132
    • 0026777243 scopus 로고
    • Increased glycated Cu,Zn-superoxide dismutase levels in erythrocytes of patients with insulin-dependent diabetis mellitus
    • Kawamura N, Ookawara T, Suzuki K, Konishi K, Mino M, Taniguchi N. Increased glycated Cu,Zn-superoxide dismutase levels in erythrocytes of patients with insulin-dependent diabetis mellitus. J Clin Endocrinol Metab 1992; 74: 1352-4.
    • (1992) J Clin Endocrinol Metab , vol.74 , pp. 1352-1354
    • Kawamura, N.1    Ookawara, T.2    Suzuki, K.3    Konishi, K.4    Mino, M.5    Taniguchi, N.6
  • 133
    • 0028206401 scopus 로고
    • Plasma endothelin levels and vascular effects of intravenous L arginine infusion in subjects with uncomplicated insulin dependent diabetes mellitus
    • Smulders RA, Stehouwer CD, Olthof CG, van Kamp GJ, Teerlink T, de Vries PM, et al. Plasma endothelin levels and vascular effects of intravenous L arginine infusion in subjects with uncomplicated insulin dependent diabetes mellitus. Clin Sci 1994; 87: 37-43.
    • (1994) Clin Sci , vol.87 , pp. 37-43
    • Smulders, R.A.1    Stehouwer, C.D.2    Olthof, C.G.3    van Kamp, G.J.4    Teerlink, T.5    de Vries, P.M.6
  • 134
  • 135
    • 0033894543 scopus 로고    scopus 로고
    • Interaction of endothelin-1 with vasoactive factors in mediating glucose-induced increased permeability in endothelial cells
    • Chen S, Apostolova M, Cherian G, Charkrabarti S. Interaction of endothelin-1 with vasoactive factors in mediating glucose-induced increased permeability in endothelial cells. Lab Invest 2000; 80: 1311-21.
    • (2000) Lab Invest , vol.80 , pp. 1311-1321
    • Chen, S.1    Apostolova, M.2    Cherian, G.3    Charkrabarti, S.4
  • 136
    • 0032740245 scopus 로고    scopus 로고
    • Endogenous nitric oxide synthesis: Biological functions and pathophysiology
    • Bredt DS. Endogenous nitric oxide synthesis: biological functions and pathophysiology. Free Radic Res 1999; 31: 577-96.
    • (1999) Free Radic Res , vol.31 , pp. 577-596
    • Bredt, D.S.1
  • 137
    • 0033219947 scopus 로고    scopus 로고
    • Cellular signaling with nitric oxide and cyclic GMP
    • Murad F. Cellular signaling with nitric oxide and cyclic GMP. Braz J Med Biol Res 1999; 32: 1317-27.
    • (1999) Braz J Med Biol Res , vol.32 , pp. 1317-1327
    • Murad, F.1
  • 138
    • 0032949402 scopus 로고    scopus 로고
    • Flow regulation of ecNOS and Cu/Zn SOD mRNA expression in porcine coronary arterioles
    • Woodman CR, Muller JM, Rush JW, Laughlin MH, Price EM. Flow regulation of ecNOS and Cu/Zn SOD mRNA expression in porcine coronary arterioles. Am J Physiol 1999; 276: H1058-63.
    • (1999) Am J Physiol , vol.276
    • Woodman, C.R.1    Muller, J.M.2    Rush, J.W.3    Laughlin, M.H.4    Price, E.M.5
  • 139
    • 1542373723 scopus 로고    scopus 로고
    • Endothelial nitric oxide synthase: A new paradigm for gene regulation in the injured blood vessel
    • Tai SC, Robb GB, Marsden PA. Endothelial nitric oxide synthase: a new paradigm for gene regulation in the injured blood vessel. Arterioscler Thromb Vasc Biol 2004; 24: 405-12.
    • (2004) Arterioscler Thromb Vasc Biol , vol.24 , pp. 405-412
    • Tai, S.C.1    Robb, G.B.2    Marsden, P.A.3
  • 140
    • 0036751127 scopus 로고    scopus 로고
    • Physiological mechanisms regulating the expression of endothelial-type NO synthase
    • Li H, Wallerath T, Forstermann U. Physiological mechanisms regulating the expression of endothelial-type NO synthase. Nitric Oxide 2002; 7: 132-47.
    • (2002) Nitric Oxide , vol.7 , pp. 132-147
    • Li, H.1    Wallerath, T.2    Forstermann, U.3
  • 141
    • 11044235870 scopus 로고    scopus 로고
    • Pro-oxidant role of heme oxygenase in mediating glucose-induced endothelial cell damage
    • Chen S, Khan ZA, Barbin Y, Chakrabarti S. Pro-oxidant role of heme oxygenase in mediating glucose-induced endothelial cell damage. Free Radic Res 2004; 38: 1301-10.
    • (2004) Free Radic Res , vol.38 , pp. 1301-1310
    • Chen, S.1    Khan, Z.A.2    Barbin, Y.3    Chakrabarti, S.4
  • 142
    • 0036899189 scopus 로고    scopus 로고
    • Immediate and delayed VEGF-mediated NO synthesis in endothelial cells: Role of PI3K, PKC and PLC pathways
    • Gelinas DS, Bernatchez PN, Rollin S, Bazan NG, Sirois MG. Immediate and delayed VEGF-mediated NO synthesis in endothelial cells: role of PI3K, PKC and PLC pathways. Br J Pharmacol 2002; 137: 1021-30.
    • (2002) Br J Pharmacol , vol.137 , pp. 1021-1030
    • Gelinas, D.S.1    Bernatchez, P.N.2    Rollin, S.3    Bazan, N.G.4    Sirois, M.G.5
  • 143
    • 0037013179 scopus 로고    scopus 로고
    • Functional reconstitution of endothelial nitric oxide synthase reveals the importance of serine 1179 in endothelium-dependent vasomotion
    • Scotland RS, Morales-Ruiz M, Chen Y, Yu J, Rudic RD, Fulton D, Gratton JP, et al. Functional reconstitution of endothelial nitric oxide synthase reveals the importance of serine 1179 in endothelium-dependent vasomotion. Circ Res 2002; 90: 904-10.
    • (2002) Circ Res , vol.90 , pp. 904-910
    • Scotland, R.S.1    Morales-Ruiz, M.2    Chen, Y.3    Yu, J.4    Rudic, R.D.5    Fulton, D.6    Gratton, J.P.7
  • 144
    • 0033542476 scopus 로고    scopus 로고
    • Activation of nitric oxide synthase in endothelial cells by Akt-dependent phosphorylation
    • Dimmeler S, Fleming I, Fisslthaler B, Hermann C, Busse R, Zeiher AM. Activation of nitric oxide synthase in endothelial cells by Akt-dependent phosphorylation. Nature 1999; 399: 601-5.
    • (1999) Nature , vol.399 , pp. 601-605
    • Dimmeler, S.1    Fleming, I.2    Fisslthaler, B.3    Hermann, C.4    Busse, R.5    Zeiher, A.M.6
  • 145
    • 0033559692 scopus 로고    scopus 로고
    • Hyper-cholesterolemia decreases nitric oxide production by promoting the interaction of caveolin and endothelial nitric oxide synthase
    • Feron O, Dessy C, Moniotte S, Desager JP, Balligand JL. Hyper-cholesterolemia decreases nitric oxide production by promoting the interaction of caveolin and endothelial nitric oxide synthase. J Clin Invest 1999; 103: 897-905.
    • (1999) J Clin Invest , vol.103 , pp. 897-905
    • Feron, O.1    Dessy, C.2    Moniotte, S.3    Desager, J.P.4    Balligand, J.L.5
  • 146
    • 0029116310 scopus 로고
    • Endothelins
    • Levin ER. Endothelins. N Engl J Med 1995; 333: 356-63.
    • (1995) N Engl J Med , vol.333 , pp. 356-363
    • Levin, E.R.1
  • 147
    • 0030477840 scopus 로고    scopus 로고
    • Mechanisms of increased endothelial permeability
    • Lum H, Malik AB. Mechanisms of increased endothelial permeability. Can J Physiol Pharmacol 1996; 74: 787-800.
    • (1996) Can J Physiol Pharmacol , vol.74 , pp. 787-800
    • Lum, H.1    Malik, A.B.2
  • 148
    • 13844269581 scopus 로고    scopus 로고
    • Glucose-induced oncofetal fibronectin in angiogenesis and signal transduction in vascular endothelial cells
    • Khan ZA, Barbin YP, and Chakrabarti S. Glucose-induced oncofetal fibronectin in angiogenesis and signal transduction in vascular endothelial cells. Diabetes 2004; 53: A443.
    • (2004) Diabetes , vol.53
    • Khan, Z.A.1    Barbin, Y.P.2    Chakrabarti, S.3
  • 149
    • 0032728365 scopus 로고    scopus 로고
    • Mitogen-activated protein kinases as glucose transducers for diabetic complications
    • Tomlinson DR. Mitogen-activated protein kinases as glucose transducers for diabetic complications. Diabetologia 1999; 42: 1271-81.
    • (1999) Diabetologia , vol.42 , pp. 1271-1281
    • Tomlinson, D.R.1
  • 150
    • 0033023620 scopus 로고    scopus 로고
    • Mechanisms of mitogen-activated protein kinase activation in experimental diabetes
    • Awazu M, Ishikura K, Hida M, Hoshiya M. Mechanisms of mitogen-activated protein kinase activation in experimental diabetes. J Am Soc Nephrol 1999; 10: 738-45.
    • (1999) J Am Soc Nephrol , vol.10 , pp. 738-745
    • Awazu, M.1    Ishikura, K.2    Hida, M.3    Hoshiya, M.4
  • 151
    • 4344609666 scopus 로고    scopus 로고
    • High expression of PKC-MAPK pathway mRNAs correlates with glomerular lesions in human diabetic nephropathy
    • Toyoda M, Suzuki D, Honma M, Uehara G, Sakai T, Umezono T, et al. High expression of PKC-MAPK pathway mRNAs correlates with glomerular lesions in human diabetic nephropathy. Kidney Int 2004; 66: 1107-14.
    • (2004) Kidney Int , vol.66 , pp. 1107-1114
    • Toyoda, M.1    Suzuki, D.2    Honma, M.3    Uehara, G.4    Sakai, T.5    Umezono, T.6
  • 152
    • 0347360288 scopus 로고    scopus 로고
    • ERK and p38 mediate high-glucose-induced hypertrophy and TGF-beta expression in renal tubular cells
    • Fujita H, Omori S, Ishikura K, Hida M, Awazu M. ERK and p38 mediate high-glucose-induced hypertrophy and TGF-beta expression in renal tubular cells. Am J Physiol Renal Physiol 2004; 286: F120-6.
    • (2004) Am J Physiol Renal Physiol , vol.286
    • Fujita, H.1    Omori, S.2    Ishikura, K.3    Hida, M.4    Awazu, M.5
  • 153
    • 3042742246 scopus 로고    scopus 로고
    • Mitogen-activated protein kinase p38 mediates reduced nerve conduction velocity in experimental diabetic neuropathy: Interactions with aldose reductase
    • Price SA, Agthong S, Middlemas AB, Tomlinson DR. Mitogen-activated protein kinase p38 mediates reduced nerve conduction velocity in experimental diabetic neuropathy: interactions with aldose reductase. Diabetes 2004; 53: 1851-6.
    • (2004) Diabetes , vol.53 , pp. 1851-1856
    • Price, S.A.1    Agthong, S.2    Middlemas, A.B.3    Tomlinson, D.R.4
  • 154
    • 2442550992 scopus 로고    scopus 로고
    • Streptozotocin directly impairs cardiac contractile function in isolated ventricular myocytes via a p38 map kinase-dependent oxidative stress mechanism
    • Wold LE, Ren J. Streptozotocin directly impairs cardiac contractile function in isolated ventricular myocytes via a p38 map kinase-dependent oxidative stress mechanism. Biochem Biophys Res Commun 2004; 318: 1066-71.
    • (2004) Biochem Biophys Res Commun , vol.318 , pp. 1066-1071
    • Wold, L.E.1    Ren, J.2
  • 155
    • 34249048522 scopus 로고    scopus 로고
    • High glucose-induced protein kinse B mediates nuclear factor-kB activation and fibronectin expression in endothelial cells
    • Xin X, Khan ZA, Chen S, Chakrabarti S. High glucose-induced protein kinse B mediates nuclear factor-kB activation and fibronectin expression in endothelial cells. Can J Diabetes 2004; 28: A200.
    • (2004) Can J Diabetes , vol.28
    • Xin, X.1    Khan, Z.A.2    Chen, S.3    Chakrabarti, S.4
  • 156
    • 34249042568 scopus 로고    scopus 로고
    • Serum-and glucocorticoid-regulated kinase mediated, glucose-induced, fibronectin upegulation in endothelial cells
    • Barbin YP, Khan ZA, Norbert B, Scholz W, Chakrabarti S. Serum-and glucocorticoid-regulated kinase mediated, glucose-induced, fibronectin upegulation in endothelial cells. Diabetes 2004; 53: 86LB.
    • (2004) Diabetes , vol.53
    • Barbin, Y.P.1    Khan, Z.A.2    Norbert, B.3    Scholz, W.4    Chakrabarti, S.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.