Oxidative stress and diabetic vascular complications

Current Diabetes Reports

Volumn 4, Issue 4, 2004, Pages 247-252

  Son, Seok M ^b   Whalin, Matthew K ^b   Harrison, David G ^b   Taylor, W Robert ^b   Griendling, Kathy K ^a  

^a EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA TOCOPHEROL; ANGIOTENSIN RECEPTOR ANTAGONIST; ANTIOXIDANT; ASCORBIC ACID; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; GLUCOSE; PROTEIN KINASE C BETA; PROTEIN KINASE C INHIBITOR; REACTIVE OXYGEN METABOLITE; RUBOXISTAURIN; THIOCTIC ACID;

ANTIOXIDANT ACTIVITY; CELL GROWTH; CELL MIGRATION; CLINICAL TRIAL; DIABETIC ANGIOPATHY; DIABETIC MICROANGIOPATHY; DIABETIC NEPHROPATHY; DIABETIC NEUROPATHY; DIABETIC RETINOPATHY; DRUG MECHANISM; DRUG TARGETING; EXTRACELLULAR MATRIX; GLUCOSE BLOOD LEVEL; HUMAN; HYPERGLYCEMIA; MORBIDITY; MORTALITY; NONHUMAN; OXIDATIVE STRESS; PATHOGENESIS; PHENOTYPE; REVIEW; SIGNAL TRANSDUCTION; VASCULAR ENDOTHELIUM; VASCULAR SMOOTH MUSCLE; VASODILATATION;

EID: 4444356029     PISSN: 15344827     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11892-004-0075-8     Document Type: Review

References (51)

1. The effect of intensive treatment of diabetes on the development and progression of long-term complications in insulin-dependent diabetes mellitus. The Diabetes Control and Complications Trial Research Group [no authors listed]. N Engl J Med 1993, 329:977-986.
2. Intensive blood-glucose control with sulphonylureas or insulin compared with conventional treatment and risk of complications in patients with type 2 diabetes (UKPDS 33). UK Prospective Diabetes Study (UKPDS) Group [no authors listed]. Lancet 1998, 352:837-853.
3. Griendling KK, FitzGerald GA: Oxidative stress and cardiovascular injury. Part II: animal and human studies. Circulation 2003, 108:2034-2040.
4. Hink U, Li H, Mollnau H, et al.: Mechanisms underlying endothelial dysfunction in diabetes mellitus. Circ Res 2001, 88:E14-E22.
5. Ceriello A: New insights on oxidative stress and diabetic complications may lead to a "causal" antioxidant therapy. Diabetes Care 2003, 26:1589-1596.
6. Evans JL, Goldfine ID, Maddux BA, Grodsky GM: Oxidative stress and stress-activated signaling pathways: a unifying hypothesis of type 2 diabetes. Endocr Rev 2002, 23:599-622.
7. DeFronzo RA: Pathogenesis of type 2 diabetes: metabolic and molecular implications for identifying diabetes genes. Diabetes Rev 1997, 5:177-269.
8. Brownlee M: Biochemistry and molecular cell biology of diabetic complications. Nature 2001, 414:813-820.
9. Sheetz MJ, King GL: Molecular understanding of hyperglycemia's adverse effects for diabetic complications. JAMA 2002, 288:2579-2588.
10. Bierman EL: George Lyman Duff Memorial Lecture. Atherogenesis in diabetes. Arterioscler Thromb 1992, 12:647-656.
11. Bowie A, Owens D, Collins P, et al.: Glycosylated low density lipoprotein is more sensitive to oxidation: implications for the diabetic patient? Atherosclerosis 1993, 102:63-67.
12. Ceriello A: Coagulation activation in diabetes mellitus: the role of hyperglycaemia and therapeutic prospects. Diabetologia 1993, 36:1119-1125.
13. Kiuchi K, Nejima J, Takano T, et al.: Increased serum concentrations of advanced glycation end products: a marker of coronary artery disease activity in type 2 diabetic patients. Heart 2001, 85:87-91.
14. Park L, Raman KG, Lee KJ, et al.: Suppression of accelerated diabetic atherosclerosis by the soluble receptor for advanced glycation endproducts. Nat Med 1998, 4:1025-1031.
15. Wautier MP, Chappey O, Corda S, et al.: Activation of NADPH oxidase by AGE links oxidant stress to altered gene expression via RAGE. Am J Physiol Endocrinol Metab 2001, 280:E685-E694.
16. Taniyama Y, Griendling KK: Reactive oxygen species in the vasculature: molecular and cellular mechanisms. Hypertension 2003, 42:1075-1081.
17. Koya D, Haneda M, Kikkawa R, King GL: d-alpha-tocopherol treatment prevents glomerular dysfunctions in diabetic rats through inhibition of protein kinase C-diacylglycerol pathway. Biofactors 1998, 7:69-76.
18. Mohamed AK, Bierhaus A, Schiekofer S, et al.: The role of oxidative stress and NF-kappaB activation in late diabetic complications. Biofactors 1999, 10:157-167.
19. Ho FM, Liu SH, Liau CS, et al.: High glucose-induced apoptosis in human endothelial cells is mediated by sequential activations of c-Jun NH(2)-terminal kinase and caspase-3. Circulation 2000, 101:2618-2624.
20. Inoguchi T, Li P, Umeda F, et al.: High glucose level and free fatty acid stimulate reactive oxygen species production through protein kinase C-dependent activation of NAD(P)H oxidase in cultured vascular cells. Diabetes 2000, 49:1939-1945.
21. Ishii H, Jirousek MR, Koya D, et al.: Amelioration of vascular dysfunctions in diabetic rats by an oral PKC beta inhibitor. Science 1996, 272:728-731.
22. Kakimoto M, Inoguchi T, Sonta T, et al.: Accumulation of 8-hydroxy-2′-deoxyguanosine and mitochondrial DNA deletion in kidney of diabetic rats. Diabetes 2002, 51:1588-1595.
23. Leinonen J, Lehtimaki T, Toyokuni S, et al.: New biomarker evidence of oxidative DNA damage in patients with non-insulin-dependent diabetes mellitus. FEBS Lett 1997, 417:150-152.
24. Williams SB, Cusco JA, Roddy MA, et al.: Impaired nitric oxide-mediated vasodilation in patients with non-insulin-dependent diabetes mellitus. J Am Coll Cardiol 1996, 27:567-574.
25. Kim YK, Lee MS, Son SM, et al.: Vascular NADH oxidase is involved in impaired endothelium-dependent vasodilation in OLETF rats, a model of type 2 diabetes. Diabetes 2002, 51:522-527.
26. Spitaler MM, Graier WF: Vascular targets of redox signalling in diabetes mellitus. Diabetologia 2002, 45:476-494.
27. Garcia Soriano F, Virag L, Jagtap P, et al.: Diabetic endothelial dysfunction: the role of poly(ADP-ribose) polymerase activation. Nat Med 2001, 7:108-113.
28. Park KS, Kim JH, Kim MS, et al.: Effects of insulin and anti-oxidant on plasma 8-hydroxyguanine and tissue 8-hydroxydeoxyguanosine in streptozotocin-induced diabetic rats. Diabetes 2001, 50:2837-2841.
29. Suzuki LA, Poot M, Gerrity RC, Bomfeldt KE: Diabetes accelerates smooth muscle accumulation in lesions of atherosclerosis: lack of direct growth-promoting effects of high glucose levels. Diabetes 2001, 50:851-860.
30. Watson PA, Nesterova A, Burant CF, et al.: Diabetes-related changes in cAMP response element-binding protein content enhance smooth muscle cell proliferation and migration. J Biol Chem 2001, 276:46142-46150.
31. Fukumoto H, Naito Z, Asano G, Aramaki T: Immunohistochemical and morphometric evaluations of coronary atherosclerotic plaques associated with myocardial infarction and diabetes mellitus. J Atheroscler Thromb 1998, 5:29-35.
32. Uemura S, Matsushita H, Li W, et al.: Diabetes mellitus enhances vascular matrix metalloproteinase activity: role of oxidative stress. Circ Res 2001, 88:1291-1298.
33. Kashihara N, Watanabe Y, Makino H, et al.: Selective decreased de novo synthesis of glomerular proteoglycans under the influence of reactive oxygen species. Proc Natl Acad Sci U S A 1992, 89:6309-6313.
34. Etoh T, Inoguchi T, Kakimoto M, et al.: Increased expression of NAD(P)H oxidase subunits, NOX4 and p22phox, in the kidney of streptozotocin-induced diabetic rats and its reversibity by interventive insulin treatment. Diabetologia 2003, 46:1428-1437.
35. 2, vascular endothelial growth factor and receptors in the retina of the BBZ/Wor diabetic rat. Free Radic Biol Med 2000, 28:91-101.
36. Cameron NE, Cotter MA, Archibald V, et al.: Anti-oxidant and pro-oxidant effects on nerve conduction velocity, endoneurial blood flow and oxygen tension in non-diabetic and streptozotocin-diabetic rats. Diabetologia 1994, 37:449-459.
37. Cameron NE, Cotter MA: Neurovascular dysfunction in diabetic rats. Potential contribution of autoxidation and free radicals examined using transition metal chelating agents. J Clin Invest 1995, 96:1159-1163.
38. Cameron NE, Cotter MA: Effects of antioxidants on nerve and vascular dysfunction in experimental diabetes. Diabetes Res Clin Pract 1999, 45:137-146.
39. Abiko T, Abiko A, Clermont AC, et al.: Characterization of retinal leukostasis and hemodynamics in insulin resistance and diabetes: role of oxidants and protein kinase-C activation. Diabetes 2003, 52:829-837.
40. Kunisaki M, Bursell SE, Clermont AC, et al.: Vitamin E prevents diabetes-induced abnormal retinal blood flow via the diacylglycerol-protein kinase C pathway. Am J Physiol 1995, 269:E239-E246.
41. Onozato ML, Tojo A, Goto A, et al.: Oxidative stress and nitric oxide synthase in rat diabetic nephropathy: effects of ACEI and ARB. Kidney Int 2002, 61:186-194.
42. Nassar T, Kadery B, Lotan C, et al.: Effects of the superoxide dismutase-mimetic compound tempol on endothelial dysfunction in streptozotocin-induced diabetic rats. Eur J Pharmacol 2002, 436:111-118.
43. Coppey IJ, Gellett JS, Davidson EP, et al.: Effect of M40403 treatment of diabetic rats on endoneurial blood flow, motor nerve conduction velocity and vascular function of epineurial arterioles of the sciatic nerve. Br J Pharmacol 2001, 134:21-29.
44. Cotter MA, Cameron NE, Keegan A, Dines KC: Effects of acetyl- and proprionyl-L-carnitine on peripheral nerve function and vascular supply in experimental diabetes. Metabolism 1995, 44:1209-1214.
45. Packer L, Kraemer K, Rimbach G: Molecular aspects of lipoic acid in the prevention of diabetes complications. Nutrition 2001, 17:888-895.
46. Brenner BM, Cooper ME, de Zeeuw D, et al.: Effects of losartan on renal and cardiovascular outcomes in patients with type 2 diabetes and nephropathy. N Engl J Med 2001, 345:861-869.
47. O'Driscoll G, Green D, Maiorana A, et al.: Improvement in endothelial function by angiotensin-converting enzyme inhibition in non-insulin-dependent diabetes mellitus. J Am Coll Cardiol 1999, 33:1506-1511.
48. Arcaro G, Zenere BM, Saggiani F, et al.: ACE inhibitors improve endothelial function in type 1 diabetic patients with normal arterial pressure and microalbuminuria. Diabetes Care 1999, 22:1536-1542.
49. Vanhoutte PM, Boulanger CM, Mombouli JV. Endothelium-derived relaxing factors and converting enzyme inhibition. Am J Cardiol 1995, 76:3E-12E.
50. Beckman JA, Goldfine AB, Gordon MB, Creager MA: Ascorbate restores endothelium-dependent vasodilation impaired by acute hyperglycemia in humans. Circulation 2001, 103:1618-1623.
51. Yusuf S, Dagenais G, Pogue J, et al.: Vitamin E supplementation and cardiovascular events in high-risk patients. The Heart Outcomes Prevention Evaluation Study Investigators. N Engl J Med 2000, 342:154-160.