Extracellular signal-regulated kinase (ERK) in glucose-induced and endothelin-mediated fibronectin synthesis

Laboratory Investigation

Volumn 84, Issue 11, 2004, Pages 1451-1459

  Xin, Xiping ^a   Khan, Zia A ^a   Chen, Shali ^a   Chakrabarti, Subrata ^a  

^a UNIVERSITY OF WESTERN ONTARIO   (Canada)

Author keywords

Endothelin 1; Fibronectin; Gene expression; Glucose; MAP kinase (ERK1 2); Protein kinase C

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; BOSENTAN; CHELERYTHRINE; ENDOTHELIN; ENDOTHELIN 1; FIBRONECTIN; GLUCOSE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MATRIX PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN KINASE C; SCLEROPROTEIN; TRANSCRIPTION FACTOR AP 1;

ARTICLE; BASEMENT MEMBRANE; CELL VIABILITY; CONFOCAL MICROSCOPY; CONTROLLED STUDY; DIABETIC ANGIOPATHY; ENDOTHELIUM CELL; ENZYME ACTIVATION; GEL MOBILITY SHIFT ASSAY; GENE EXPRESSION; HUMAN; HUMAN CELL; IMMUNOBLOTTING; INCUBATION TIME; MOLECULAR MECHANICS; NUCLEAR LOCALIZATION SIGNAL; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN PURIFICATION; PROTEIN SYNTHESIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA ISOLATION; SIGNAL TRANSDUCTION; UPREGULATION;

ALKALOIDS; BENZOPHENANTHRIDINES; CA(2+)-CALMODULIN DEPENDENT PROTEIN KINASE; CELL NUCLEUS; CELLS, CULTURED; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOTHELIN-1; ENDOTHELIUM, VASCULAR; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; FIBRONECTINS; FLAVONOIDS; GLUCOSE; HUMANS; MICROSCOPY, CONFOCAL; PHENANTHRIDINES; PROTEIN KINASE C; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SULFONAMIDES; UMBILICAL VEINS; UP-REGULATION;

EID: 8344248674     PISSN: 00236837     EISSN: None     Source Type: Journal    
DOI: 10.1038/labinvest.3700178     Document Type: Article

References (35)

1. Khan ZA, Chakrabarti S. Endothelins in chronic diabetic complications. Can J Physiol Pharmacol 2003;81:622-634.
2. Chakrabarti S, Khan ZA, Cukiernik M, et al. Alteration of endothelins: a common pathogenetic mechanism in chronic diabetic complications. Int J Exp Diabetes Res 2002;3:217-231.
3. Ljubimov AV, Burgeson RE, Butkowski RJ, et al. Basement membrane abnormalities in human eyes with diabetic retinopathy. J Histochem Cytochem 1996;44:1469-1479.
4. Evans T, Deng DX, Chen S, et al. Endothelin receptor blockade prevents augmented extracellular matrix protein component mRNA expression and capillary basement membrane thickening in the retina of diabetic and galactose fed rats. Diabetes 2000;49: 662-666.
5. Roy S, Cagliero E, Lorenzi M. Fibronectin overexpression in retinal microvessels of patients with diabetes. Invest Ophthalmol Vis Sci 1996;37:258-266.
6. Chen S, Mukherjee S, Chakraborty C, et al. High glucose-induced endothelin-1 dependent fibronectin synthesis is mediated via NF-κB and AP-1. Am J Physiol Cell Physiol 2003;284:C263-C272.
7. Yamada KM. Cell surface interactions with extracellular materials. Annu Rev Biochem 1983;52:761-799.
8. Isono M, Cruz MC, Chen S, et al. Extracellular signal-regulated kinase mediates stimulation of TGF-beta1 and matrix by high glucose in mesangial cells. J Am Soc Nephrol 2000;11:2222-2230.
9. Tomlinson DR. Mitogen-activated protein kinases as glucose transducers for diabetic complications. Diabetologia 1999;42:1271-1281.
10. Pearson G, Robinson F, Beers Gibson T, et al. Mitogen-activated protein (MAP) kinase pathways: regulation and physiological functions. Endocr Rev 2001;22: 153-183.
11. Andrew EA, Stewart AS, Assoian KR, et al. Integrin-mediated adhesion regulates ERK nuclear translocation and phosphorylation of Elk-1. J Cell Biol 2001; 153:273-282.
12. Haneda M, Kikkawa R, Sugimoto T, et al. Abnormalities in protein kinase C and MAP kinase cascade in mesangial cells cultured under high glucose conditions. J Diabetes Compile 1995;9:246-248.
13. Hua H, Goldberg HJ, Fantus IG, et al. High glucose-enhanced mesangial cell extracellular signal-regulated protein kinase activation and alpha1(IV) collagen expression in response to endothelin-1: role of specific protein kinase C isozymes. Diabetes 2001;50: 2376-2383.
14. Kyaw M, Yoshizumi M, Tsuchiya K, et al. Antioxidants inhibit endothelin-1 (1-31)-induced proliferation of vascular smooth muscle cells via the inhibition of mitogen-activated protein (MAP) kinase and activator protein-1 (AP-1). Biochem Pharmacol 2002;64: 1521-1531.
15. Chen S, Evans T, Deng D, et al. Hyperhexosemia induced functional and structural changes in the kidneys: role of endothelins. Nephron 2002;90:86-94.
16. Bozinovski S, Jones JE, Vlahos R, et al. Granulocyte/macrophage-colony- stimulating factor (GM-CSF) regulates lung innate immunity to lipopolysaccharide through Akt/ERK activation of NF kappa B and AP-1 in vivo. J Biol Chem 2002;277:42808-42814.
17. Wick W, Stock J, Seyfried J, et al. CD95/CD95 ligand-independent potentiation of treosulfan cytotoxicity by BSO in malignant glioma cells in vitro and in vivo. Int J Oncol 2002;21:213-220.
18. Chen S, Khan ZA, Cukiernik M, et al. Differential activation of NF-κB and AP-1 in increased fibronectin synthesis in target organs of diabetic complications. Am J Physiol Endocrinol Metab 2003;284:E1089-E1097.
19. Schmittgen TD, Zakrajsek BA. Effect of experimental treatment on housekeeping gene expression: validation by real-time, quantitative RT-PCR. J Biochem Biophys Methods 2000;46:69-81.
20. Chen S, Evans T, Mukherjee K, et al. Diabetes-induced myocardial structural changes: role of endothelin-1 and its receptors. J MolCell Cardiol 2000;32: 1621-1629.
21. Haneda M, Araki S, Togawa M, et al. Mitogen-activated protein kinase cascade is activated in glomeruli of diabetic rats and glomerular mesangial cells cultured under high glucose conditions. Diabetes 1997;46:847-853.
22. Haneda M, Kikkawa R, Sugimoto T, et al. Abnormalities in protein kinase C and MAP kinase cascade in mesangial cells cultured under high glucose conditions. J Diabetes Compile 1995;9:246-248.
23. Brownlee M. Biochemistry and molecular cell biology of diabetic complications. Nature 2001;414:813-820.
24. King GL, Brownlee M. The cellular and molecular mechanisms of diabetic complications. Endocrinol Metab Clin North Am 1996;25:255-270.
25. Chen S, Apostolova MD, Cherian MG, et al. Interaction of endothelin-1 with vasoactive factors in mediating glucose-induced increased permeability in endothelial cells. Lab Invest 2000;80:1311-1321.
26. Levin ER. Endothelins. N Engl J Med 1995;333: 356-363.
27. Quehenberger P, Bierhaus A, Fasching P, et al. Endothelin 1 transcription is controlled by nuclear factor-kappaB in AGE-stimulated cultured endothelial cells. Diabetes 2000;49:1561-1570.
28. Chakraborty C, Barbin YP, Chakrabarti S, et al. Endothelin-1 promotes migration and induces elevation of [Ca(2+)] (i) and phosphorylation of MAP kinase of a human extravillous trophoblast cell line. Mol Cell Endocrinol 2003;28:63-73.
29. Cheng CM, Hong HJ, Liu JC, et al. Crucial role of extracellular signal-regulated kinase pathway in reactive oxygen species-mediated endothelin-1 gene expression induced by endothelin-1 in rat cardiac fibroblasts. Mol Pharmacol 2003;63:1002-1011.
30. Kwon S, Lee WJ, Fang LH, et al. Mitogen-activated protein kinases partially regulate endothelin-1-induced contractions through a myosin light chain phosphorylation-independent pathway. J Vet Med Sci 2003;65:225-230.
31. Tamura K, Chen YE, Lopez LM, et al. Molecular mechanism of fibronectin gene activation by cyclic stretch in vascular smooth muscle cells. J Biol Chem 2000;275:34619-34627.
32. Moriguchi Y, Matsubara H, Mori Y, et al. Angiotensin II-induced transactivation of epidermal growth factor receptor regulates fibronectin and transforming growth factor-beta synthesis via transcriptional and posttranscriptional mechanisms. Circ Res 1999;84:1073-1084.
33. Tamura K, Nyui N, Tamura N, et al. Mechanism of angiotensin II-mediated regulation of fibronectin gene in rat vascular smooth muscle cells. J Biol Chem 1998;273:26487-26496.
34. Lee BH, Kim MS, Rhew JH, et al. Transcriptional regulation of fibronectin gene by phorbol myristate acetate in hepatoma cells: a negative role for NF-kappa B. J Cell Biochem 2000;76:437-451.
35. Morigi M, Angioletti S, Imberti B, et al. Leukocyte-endothelial interaction is augmented by high glucose concentrations and hyperglycemia in a NF-κB-dependent fashion. J Clin Invest 1998;101:1905-1915.