메뉴 건너뛰기




Volumn 45, Issue 2-3, 1999, Pages 137-146

Effects of antioxidants on nerve and vascular dysfunction in experimental diabetes

Author keywords

Lipoic acid; Antioxidant; Blood flow; Diabetes; Free radicals; Ischemia; Nerve conduction velocity; Neuropathy; Nitric oxide; Vascular endothelium; Vitamin E

Indexed keywords

ACETYLCYSTEINE; ALDOSE REDUCTASE INHIBITOR; ALPHA TOCOPHEROL; AMINOGUANIDINE; ANTIOXIDANT; ASCORBIC ACID; ASCORBYL GAMMA LINOLENIC ACID; BETA CAROTENE; BUTYLCRESOL; DEFEROXAMINE; FREE RADICAL; GAMMA LINOLENIC ACID; GLUTATHIONE; NITRIC OXIDE; PROBUCOL; PROSTANOID; THIOCTIC ACID; TRIENTINE; UNCLASSIFIED DRUG;

EID: 0032836681     PISSN: 01688227     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0168-8227(99)00043-1     Document Type: Article
Times cited : (162)

References (67)
  • 1
    • 0024814465 scopus 로고
    • Nerve blood flow and oxygen delivery in normal, diabetic and ischemic neuropathy
    • Low P.A., Lagerlund T.D., McManis P.G. Nerve blood flow and oxygen delivery in normal, diabetic and ischemic neuropathy. Int. Rev. Neurobiol. 31:1989;355-438.
    • (1989) Int. Rev. Neurobiol. , vol.31 , pp. 355-438
    • Low, P.A.1    Lagerlund, T.D.2    McManis, P.G.3
  • 2
    • 0028095119 scopus 로고
    • Vascular factors in diabetic neuropathy
    • Tesfaye S., Malik R., Ward J.D. Vascular factors in diabetic neuropathy. Diabetologia. 37:1994;847-854.
    • (1994) Diabetologia , vol.37 , pp. 847-854
    • Tesfaye, S.1    Malik, R.2    Ward, J.D.3
  • 3
    • 0028040725 scopus 로고
    • The relationship of vascular changes to metabolic factors in diabetes mellitus and their role in the development of peripheral nerve complications
    • Cameron N.E., Cotter M.A. The relationship of vascular changes to metabolic factors in diabetes mellitus and their role in the development of peripheral nerve complications. Diabetes Metab. Rev. 10:1994;189-224.
    • (1994) Diabetes Metab. Rev. , vol.10 , pp. 189-224
    • Cameron, N.E.1    Cotter, M.A.2
  • 4
    • 0030923990 scopus 로고    scopus 로고
    • Metabolic and vascular factors in the pathogenesis of diabetic neuropathy
    • (Suppl. 2)
    • Cameron N.E., Cotter M.A. Metabolic and vascular factors in the pathogenesis of diabetic neuropathy. Diabetes. 46:1997;S31-S37. (Suppl. 2).
    • (1997) Diabetes , vol.46
    • Cameron, N.E.1    Cotter, M.A.2
  • 5
    • 0025814611 scopus 로고
    • Nerve blood flow in early experimental diabetes in rats: Relation to conduction deficits
    • Cameron N.E., Cotter M.A., Low P.A. Nerve blood flow in early experimental diabetes in rats: relation to conduction deficits. Am. J. Physiol. 261:1991;E1-E8.
    • (1991) Am. J. Physiol. , vol.261
    • Cameron, N.E.1    Cotter, M.A.2    Low, P.A.3
  • 6
    • 0028606547 scopus 로고
    • Vascular and metabolic factors in the pathogenesis of experimental diabetic neuropathy in mature rats
    • Wright R.A., Nukada H. Vascular and metabolic factors in the pathogenesis of experimental diabetic neuropathy in mature rats. Brain. 117:1994;1395-1407.
    • (1994) Brain , vol.117 , pp. 1395-1407
    • Wright, R.A.1    Nukada, H.2
  • 7
    • 0028006515 scopus 로고
    • Nerve ischaemia in diabetic rats: Time-course of development, effects of insulin treatment plus comparison of streptozotocin and BB models
    • Stevens E.J., Carrington A.L., Tomlinson D.R. Nerve ischaemia in diabetic rats: time-course of development, effects of insulin treatment plus comparison of streptozotocin and BB models. Diabetologia. 37:1994;43-48.
    • (1994) Diabetologia , vol.37 , pp. 43-48
    • Stevens, E.J.1    Carrington, A.L.2    Tomlinson, D.R.3
  • 8
    • 0013603010 scopus 로고    scopus 로고
    • Inhibition of protein kinase C corrects nerve conduction and blood flow deficits in diabetic rats
    • (Suppl. 1)
    • Cameron N.E., Cotter M.A., Jack A., Hohman T.C. Inhibition of protein kinase C corrects nerve conduction and blood flow deficits in diabetic rats. Diabetologia. 40:1997;A31. (Suppl. 1).
    • (1997) Diabetologia , vol.40 , pp. 31
    • Cameron, N.E.1    Cotter, M.A.2    Jack, A.3    Hohman, T.C.4
  • 9
    • 0025732948 scopus 로고
    • Role of oxidative stress in the development of complications in diabetes
    • Baynes J.W. Role of oxidative stress in the development of complications in diabetes. Diabetes. 40:1991;405-412.
    • (1991) Diabetes , vol.40 , pp. 405-412
    • Baynes, J.W.1
  • 10
    • 0027279232 scopus 로고
    • Diabetes mellitus and free radicals
    • Wolff S.P. Diabetes mellitus and free radicals. Br. Med. Bull. 49:1993;642-652.
    • (1993) Br. Med. Bull. , vol.49 , pp. 642-652
    • Wolff, S.P.1
  • 12
    • 0025863547 scopus 로고
    • Oxygen free radical effects in sciatic nerve in experimental diabetes
    • Low P.A., Nickander K.K. Oxygen free radical effects in sciatic nerve in experimental diabetes. Diabetes. 40:1991;873-877.
    • (1991) Diabetes , vol.40 , pp. 873-877
    • Low, P.A.1    Nickander, K.K.2
  • 13
    • 0028069048 scopus 로고
    • Effects of α-tocopherol-deficiency on indices of oxidative stress in normal and diabetic peripheral nerve
    • Nickander K., Schmelzer J.D., Rohwer D., Low P.A. Effects of α-tocopherol-deficiency on indices of oxidative stress in normal and diabetic peripheral nerve. J. Neurol. Sci. 126:1994;6-14.
    • (1994) J. Neurol. Sci. , vol.126 , pp. 6-14
    • Nickander, K.1    Schmelzer, J.D.2    Rohwer, D.3    Low, P.A.4
  • 14
    • 0029090976 scopus 로고
    • Lipoic acid improves nerve blood flow, reduces oxidative stress and improves distal nerve conduction in experimental diabetic neuropathy
    • Nagamatsu M., Nickander K.K., Schmelzer J.D. et al. Lipoic acid improves nerve blood flow, reduces oxidative stress and improves distal nerve conduction in experimental diabetic neuropathy. Diabetes Care. 18:1995;1160-1167.
    • (1995) Diabetes Care , vol.18 , pp. 1160-1167
    • Nagamatsu, M.1    Nickander, K.K.2    Schmelzer, J.D.3
  • 15
    • 0030961020 scopus 로고    scopus 로고
    • The roles of oxidative stress and antioxidant treatment in experimental diabetic neuropathy
    • (Suppl. 2)
    • Low P.A., Nickander K.K., Tritschler H.J. The roles of oxidative stress and antioxidant treatment in experimental diabetic neuropathy. Diabetes. 46:1997;S38-S42. (Suppl. 2).
    • (1997) Diabetes , vol.46
    • Low, P.A.1    Nickander, K.K.2    Tritschler, H.J.3
  • 16
    • 0031018374 scopus 로고    scopus 로고
    • Neuropathology and blood flow of nerve, spinal roots and dorsal root ganglia in long-standing diabetic rats
    • Sasaki H., Schmelzer J.D., Zollman P.J., Low P.A. Neuropathology and blood flow of nerve, spinal roots and dorsal root ganglia in long-standing diabetic rats. Acta Neuropathol. 93:1997;118-128.
    • (1997) Acta Neuropathol. , vol.93 , pp. 118-128
    • Sasaki, H.1    Schmelzer, J.D.2    Zollman, P.J.3    Low, P.A.4
  • 17
    • 0022640297 scopus 로고
    • Superoxide anion is involved in the breakdown of endothelium-derived vascular relaxing factor
    • Gryglewski R.J., Palmer R.M.J., Moncado S. Superoxide anion is involved in the breakdown of endothelium-derived vascular relaxing factor. Nature. 320:1986;454-456.
    • (1986) Nature , vol.320 , pp. 454-456
    • Gryglewski, R.J.1    Palmer, R.M.J.2    Moncado, S.3
  • 18
    • 0025189864 scopus 로고
    • Apparent hydroxyl radical production by peroxynitrite: Implications for endothelial injury from nitric oxide and superoxide
    • Beckman J.S., Beckman T.W., Chen J., Marshall P.A., Freeman B.A. Apparent hydroxyl radical production by peroxynitrite: implications for endothelial injury from nitric oxide and superoxide. Proc. Natl. Acad. Sci. USA. 87:1990;1620-1624.
    • (1990) Proc. Natl. Acad. Sci. USA , vol.87 , pp. 1620-1624
    • Beckman, J.S.1    Beckman, T.W.2    Chen, J.3    Marshall, P.A.4    Freeman, B.A.5
  • 19
    • 0026759488 scopus 로고
    • Free radicals mediate endothelial cell dysfunction caused by elevated glucose
    • Tesfamariam B., Cohen R.A. Free radicals mediate endothelial cell dysfunction caused by elevated glucose. Am. J. Physiol. 263:1992;H321-H326.
    • (1992) Am. J. Physiol. , vol.263
    • Tesfamariam, B.1    Cohen, R.A.2
  • 20
    • 0028151070 scopus 로고
    • The effect of hyperglycaemia on function of rat isolated mesenteric resistance artery
    • Taylor P.D., Poston L. The effect of hyperglycaemia on function of rat isolated mesenteric resistance artery. Br. J. Pharmacol. 113:1994;801-808.
    • (1994) Br. J. Pharmacol. , vol.113 , pp. 801-808
    • Taylor, P.D.1    Poston, L.2
  • 21
    • 0028790808 scopus 로고
    • Chronic vitamin E treatment prevents defective endothelium-dependent relaxation in diabetic rat aorta
    • Keegan A, Walbank H., Cotter M.A., Cameron N.E. Chronic vitamin E treatment prevents defective endothelium-dependent relaxation in diabetic rat aorta. Diabetologia. 38:1995;1475-1478.
    • (1995) Diabetologia , vol.38 , pp. 1475-1478
    • Keegan, A.1    Walbank, H.2    Cotter, M.A.3    Cameron, N.E.4
  • 22
    • 0029915468 scopus 로고    scopus 로고
    • Contraction and relaxation of aortas from diabetic rats: Effects of chronic anti-oxidant and aminoguanidine treatments
    • Archibald V., Cotter M.A., Keegan A., Cameron N.E. Contraction and relaxation of aortas from diabetic rats: effects of chronic anti-oxidant and aminoguanidine treatments. Naunyn Schmiedeberg's Arch. Pharmacol. 353:1996;584-591.
    • (1996) Naunyn Schmiedeberg's Arch. Pharmacol. , vol.353 , pp. 584-591
    • Archibald, V.1    Cotter, M.A.2    Keegan, A.3    Cameron, N.E.4
  • 23
    • 0029085103 scopus 로고
    • Endothelial relaxation is disturbed by oxidative stress in the diabetic rat heart: Influence of tocopherol as antioxidant
    • Rosen P., Ballhausen T., Bloch W., Addicks K. Endothelial relaxation is disturbed by oxidative stress in the diabetic rat heart: influence of tocopherol as antioxidant. Diabetologia. 38:1995;1157-1168.
    • (1995) Diabetologia , vol.38 , pp. 1157-1168
    • Rosen, P.1    Ballhausen, T.2    Bloch, W.3    Addicks, K.4
  • 24
    • 0023713429 scopus 로고
    • Oxygen free radicals abolish endothelium-dependent relaxation in diabetic rat aorta
    • Pieper G.M., Gross G.J. Oxygen free radicals abolish endothelium-dependent relaxation in diabetic rat aorta. Am. J. Physiol. 255:1988;H825-H833.
    • (1988) Am. J. Physiol. , vol.255
    • Pieper, G.M.1    Gross, G.J.2
  • 25
    • 0026771380 scopus 로고
    • Impairment of endothelium-dependent dilatation of the basilar artery during diabetes mellitus
    • Mayhan W.G. Impairment of endothelium-dependent dilatation of the basilar artery during diabetes mellitus. Brain Res. 580:1992;297-302.
    • (1992) Brain Res. , vol.580 , pp. 297-302
    • Mayhan, W.G.1
  • 26
    • 0024309747 scopus 로고
    • Impairment of endothelium-dependent relaxation and changes in levels of cyclic GMP in aorta from streptozotocin-induced diabetic rats
    • Kamata K., Miyata N., Kasuya Y. Impairment of endothelium-dependent relaxation and changes in levels of cyclic GMP in aorta from streptozotocin-induced diabetic rats. Br. J. Pharmacol. 97:1989;614-618.
    • (1989) Br. J. Pharmacol. , vol.97 , pp. 614-618
    • Kamata, K.1    Miyata, N.2    Kasuya, Y.3
  • 27
    • 0026684462 scopus 로고
    • Impaired endothelium-dependent and independent vasodilation in patients with type 2 (non-insulin-dependent) diabetes mellitus
    • McVeigh G.E., Brennan G.M., Johnston G.D. et al. Impaired endothelium-dependent and independent vasodilation in patients with type 2 (non-insulin-dependent) diabetes mellitus. Diabetologia. 35:1992;771-776.
    • (1992) Diabetologia , vol.35 , pp. 771-776
    • McVeigh, G.E.1    Brennan, G.M.2    Johnston, G.D.3
  • 28
    • 0027522119 scopus 로고
    • Inhibition of nitric oxide synthesis in forearm vasculature of insulin-dependent diabetic patients: Blunted vasoconstriction in patients with microalbuminuria
    • Elliott T.G., Cockcroft J.R., Groop P.H., Viberti G.C., Ritter J.M. Inhibition of nitric oxide synthesis in forearm vasculature of insulin-dependent diabetic patients: blunted vasoconstriction in patients with microalbuminuria. Clin. Sci. 85:1993;687-693.
    • (1993) Clin. Sci. , vol.85 , pp. 687-693
    • Elliott, T.G.1    Cockcroft, J.R.2    Groop, P.H.3    Viberti, G.C.4    Ritter, J.M.5
  • 29
    • 0027381832 scopus 로고
    • Impaired endothelium-dependent vasodilation in patients with insulin-dependent diabetes mellitus
    • Johnstone M.T., Creager S.J., Scales K.M., Cusco J.A., Lee B.K., Creager M.A. Impaired endothelium-dependent vasodilation in patients with insulin-dependent diabetes mellitus. Circulation. 88:1993;2510-2516.
    • (1993) Circulation , vol.88 , pp. 2510-2516
    • Johnstone, M.T.1    Creager, S.J.2    Scales, K.M.3    Cusco, J.A.4    Lee, B.K.5    Creager, M.A.6
  • 30
    • 0027216069 scopus 로고
    • Impairment of coronary vascular reserve and ACh-induced coronary vasodilation in diabetic patients with angiographically normal coronary arteries and normal left ventricular systolic function
    • Nitenberg A., Valensi P., Sachs R., Dali M., Aptecar E., Attali J.R. Impairment of coronary vascular reserve and ACh-induced coronary vasodilation in diabetic patients with angiographically normal coronary arteries and normal left ventricular systolic function. Diabetes. 42:1993;1017-1025.
    • (1993) Diabetes , vol.42 , pp. 1017-1025
    • Nitenberg, A.1    Valensi, P.2    Sachs, R.3    Dali, M.4    Aptecar, E.5    Attali, J.R.6
  • 31
    • 0028793753 scopus 로고
    • Responses of the skin microcirculation to acetylcholine and sodium nitroprusside in patients with NIDDM
    • Morris S.J., Shore A.C., Tooke J.E. Responses of the skin microcirculation to acetylcholine and sodium nitroprusside in patients with NIDDM. Diabetologia. 38:1995;1337-1344.
    • (1995) Diabetologia , vol.38 , pp. 1337-1344
    • Morris, S.J.1    Shore, A.C.2    Tooke, J.E.3
  • 32
    • 0028791236 scopus 로고
    • Effects of natural free radical scavengers on peripheral nerve and neurovascular function in diabetic rats
    • Cotter M.A., Love A., Watt M.J., Cameron N.E., Dines K.C. Effects of natural free radical scavengers on peripheral nerve and neurovascular function in diabetic rats. Diabetologia. 38:1995;1285-1294.
    • (1995) Diabetologia , vol.38 , pp. 1285-1294
    • Cotter, M.A.1    Love, A.2    Watt, M.J.3    Cameron, N.E.4    Dines, K.C.5
  • 33
    • 0027502320 scopus 로고
    • Antioxidant treatment prevents the development of peripheral nerve dysfunction in streptozotocin-diabetic rats
    • Cameron N.E., Cotter M.A., Maxfield E.K. Antioxidant treatment prevents the development of peripheral nerve dysfunction in streptozotocin-diabetic rats. Diabetologia. 36:1993;299-304.
    • (1993) Diabetologia , vol.36 , pp. 299-304
    • Cameron, N.E.1    Cotter, M.A.2    Maxfield, E.K.3
  • 34
    • 0028207046 scopus 로고
    • Anti-oxidant and pro-oxidant effects on nerve conduction velocity, endoneurial blood flow and oxygen tension in non-diabetic and streptozotocin-diabetic rats
    • Cameron N.E., Cotter M.A., Archibald V., Dines K.C., Maxfield E.K. Anti-oxidant and pro-oxidant effects on nerve conduction velocity, endoneurial blood flow and oxygen tension in non-diabetic and streptozotocin-diabetic rats. Diabetologia. 37:1994;449-459.
    • (1994) Diabetologia , vol.37 , pp. 449-459
    • Cameron, N.E.1    Cotter, M.A.2    Archibald, V.3    Dines, K.C.4    Maxfield, E.K.5
  • 35
    • 0028982688 scopus 로고
    • Effects of anti-oxidant treatment on sciatic nerve dysfunction in streptozotocin-diabetic rats; Comparison with essential fatty acids
    • Karasu C., Dewhurst M., Stevens E.J., Tomlinson D.R. Effects of anti-oxidant treatment on sciatic nerve dysfunction in streptozotocin-diabetic rats; comparison with essential fatty acids. Diabetologia. 38:1995;129-134.
    • (1995) Diabetologia , vol.38 , pp. 129-134
    • Karasu, C.1    Dewhurst, M.2    Stevens, E.J.3    Tomlinson, D.R.4
  • 36
    • 0028844522 scopus 로고
    • Reversal of peripheral nerve conduction and perfusion deficits by the free radical scavenger, BM15.0639, in diabetic rats
    • Cameron N.E., Cotter M.A. Reversal of peripheral nerve conduction and perfusion deficits by the free radical scavenger, BM15.0639, in diabetic rats. Naunyn Schmiedeberg's Arch. Pharmacol. 321:1995;685-690.
    • (1995) Naunyn Schmiedeberg's Arch. Pharmacol. , vol.321 , pp. 685-690
    • Cameron, N.E.1    Cotter, M.A.2
  • 37
    • 0030022084 scopus 로고    scopus 로고
    • Inhibition of development of peripheral neuropathy in streptozotocin-induced diabetic rats with N-acetylcysteine
    • Sagara M., Satoh J., Wada R. et al. Inhibition of development of peripheral neuropathy in streptozotocin-induced diabetic rats with N-acetylcysteine. Diabetologia. 39:1996;263-269.
    • (1996) Diabetologia , vol.39 , pp. 263-269
    • Sagara, M.1    Satoh, J.2    Wada, R.3
  • 38
    • 0029780545 scopus 로고    scopus 로고
    • Effects of the sulphydryl donor, N-acetyl-L-cysteine, on nerve conduction, perfusion, maturation, and regeneration following freeze-damage in diabetic rats
    • Love A., Cotter M.A., Cameron N.E. Effects of the sulphydryl donor, N-acetyl-L-cysteine, on nerve conduction, perfusion, maturation, and regeneration following freeze-damage in diabetic rats. Eur. J. Clin. Invest. 26:1996;698-706.
    • (1996) Eur. J. Clin. Invest. , vol.26 , pp. 698-706
    • Love, A.1    Cotter, M.A.2    Cameron, N.E.3
  • 39
    • 0029764551 scopus 로고    scopus 로고
    • Alpha-lipoic acid: Antioxidant potency against lipid peroxidation of neural tissues in vitro and implications for diabetic neuropathy
    • Nickander K.K., McPhee B.R., Low P.A., Tritschler H. Alpha-lipoic acid: antioxidant potency against lipid peroxidation of neural tissues in vitro and implications for diabetic neuropathy. Free Rad. Biol. Med. 21:1996;631-639.
    • (1996) Free Rad. Biol. Med. , vol.21 , pp. 631-639
    • Nickander, K.K.1    McPhee, B.R.2    Low, P.A.3    Tritschler, H.4
  • 40
    • 0031944812 scopus 로고    scopus 로고
    • Effects of α-lipoic acid on neurovascular function in diabetic rats: interaction with essential fatty acids
    • N.E. Cameron, M.A. Cotter, D.H. Horrobin, H.J. Tritschler, Effects of α-lipoic acid on neurovascular function in diabetic rats: interaction with essential fatty acids, Diabetologia 41 (1998) 390-399.
    • (1998) Diabetologia , vol.41 , pp. 390-399
    • Cameron, N.E.1    Cotter, M.A.2    Horrobin, D.H.3    Tritschler, H.J.4
  • 41
    • 0029082815 scopus 로고
    • Neurovascular dysfunction in diabetic rats: Potential contribution of autoxidation and free radicals examined using transition metal chelating agents
    • Cameron N.E., Cotter M.A. Neurovascular dysfunction in diabetic rats: potential contribution of autoxidation and free radicals examined using transition metal chelating agents. J. Clin. Invest. 96:1995;1159-1163.
    • (1995) J. Clin. Invest. , vol.96 , pp. 1159-1163
    • Cameron, N.E.1    Cotter, M.A.2
  • 42
    • 0031425142 scopus 로고    scopus 로고
    • Diabetes-induced endothelial dysfunction is prevented by long-term treatment with the modified iron chelator, hydroxyethyl starch conjugated-deferoxamine
    • G.M. Pieper, W. Siebeneich, Diabetes-induced endothelial dysfunction is prevented by long-term treatment with the modified iron chelator, hydroxyethyl starch conjugated-deferoxamine, J. Cardiovasc. Pharmacol. 31 (1997) 734-738.
    • (1997) J. Cardiovasc. Pharmacol. , vol.31 , pp. 734-738
    • Pieper, G.M.1    Siebeneich, W.2
  • 43
    • 11944272384 scopus 로고
    • Glycation products and the pathogenesis of diabetic complications
    • Brownlee M. Glycation products and the pathogenesis of diabetic complications. Diabetes Care. 15:1992;1835-1843.
    • (1992) Diabetes Care , vol.15 , pp. 1835-1843
    • Brownlee, M.1
  • 44
    • 0023885730 scopus 로고
    • Glutathione depletion in the lens of galactosemic and diabetic rats
    • Lou M.F., Dickerson J.E., Garadi R., York B.M. Glutathione depletion in the lens of galactosemic and diabetic rats. Exp. Eye Res. 46:1988;517-530.
    • (1988) Exp. Eye Res. , vol.46 , pp. 517-530
    • Lou, M.F.1    Dickerson, J.E.2    Garadi, R.3    York, B.M.4
  • 45
    • 0001410975 scopus 로고    scopus 로고
    • Increased oxidative stress in experimental diabetic neuropathy
    • (Suppl. 1)
    • Hohman T.C., Banas D., Basso M., Cotter M.A., Cameron N.E. Increased oxidative stress in experimental diabetic neuropathy. Diabetologia. 40:1997;A549. (Suppl. 1).
    • (1997) Diabetologia , vol.40 , pp. 549
    • Hohman, T.C.1    Banas, D.2    Basso, M.3    Cotter, M.A.4    Cameron, N.E.5
  • 47
    • 0030432243 scopus 로고    scopus 로고
    • A antagonist on neurovascular function in diabetic rats: Interaction with the renin-angiotensin system
    • A antagonist on neurovascular function in diabetic rats: interaction with the renin-angiotensin system. J. Pharmacol. Exp. Ther. 278:1996;1262-1268.
    • (1996) J. Pharmacol. Exp. Ther. , vol.278 , pp. 1262-1268
    • Cameron, N.E.1    Cotter, M.A.2
  • 48
    • 0029011459 scopus 로고
    • Impaired vasoreactivity to nitric oxide in experimental diabetic neuropathy
    • Kihara M., Low P.A. Impaired vasoreactivity to nitric oxide in experimental diabetic neuropathy. Exp. Neurol. 132:1995;180-185.
    • (1995) Exp. Neurol. , vol.132 , pp. 180-185
    • Kihara, M.1    Low, P.A.2
  • 49
    • 0031040690 scopus 로고    scopus 로고
    • Effects of diabetes on reactivity of sciatic vasa nervorum in rats
    • Maxfield E.K., Cameron N.E., Cotter M.A. Effects of diabetes on reactivity of sciatic vasa nervorum in rats. J. Diabet. Complications. 11:1997;47-55.
    • (1997) J. Diabet. Complications , vol.11 , pp. 47-55
    • Maxfield, E.K.1    Cameron, N.E.2    Cotter, M.A.3
  • 50
    • 0030600493 scopus 로고    scopus 로고
    • Nerve function and regeneration in diabetic and galactosaemic rats: Antioxidant and metal chelator effects
    • Love A., Cotter M.A., Cameron N.E. Nerve function and regeneration in diabetic and galactosaemic rats: antioxidant and metal chelator effects. Eur. J. Pharmacol. 314:1996;33-39.
    • (1996) Eur. J. Pharmacol. , vol.314 , pp. 33-39
    • Love, A.1    Cotter, M.A.2    Cameron, N.E.3
  • 51
    • 0031014302 scopus 로고    scopus 로고
    • Effects of α-tocopherol on nerve conduction velocity and regeneration following a freeze lesion in immature diabetic rats
    • Love A., Cotter M.A., Cameron N.E. Effects of α-tocopherol on nerve conduction velocity and regeneration following a freeze lesion in immature diabetic rats. Naunyn Schmeideberg's Arch. Pharmacol. 355:1997;126-130.
    • (1997) Naunyn Schmeideberg's Arch. Pharmacol. , vol.355 , pp. 126-130
    • Love, A.1    Cotter, M.A.2    Cameron, N.E.3
  • 52
    • 0026701472 scopus 로고
    • Ascorbic acid oxidation: A potential cause of the elevated severity of atherosclerosis in diabetes mellitus
    • Hunt J.V., Bottoms M.A., Mitchison M.J. Ascorbic acid oxidation: a potential cause of the elevated severity of atherosclerosis in diabetes mellitus. FEBS Lett. 311:1992;161-164.
    • (1992) FEBS Lett. , vol.311 , pp. 161-164
    • Hunt, J.V.1    Bottoms, M.A.2    Mitchison, M.J.3
  • 53
    • 0018348794 scopus 로고
    • Direct observation of a free radical interaction between vitamin E and vitamin C
    • Packer L.E., Slater T.F., Wilson R.L. Direct observation of a free radical interaction between vitamin E and vitamin C. Nature. 278:1979;737-738.
    • (1979) Nature , vol.278 , pp. 737-738
    • Packer, L.E.1    Slater, T.F.2    Wilson, R.L.3
  • 54
    • 0009561761 scopus 로고    scopus 로고
    • Autonomic neuropathy, corpus cavernosum innervation and endothelial responses: Diabetic defects prevented by α-lipoic acid in rats
    • Keegan A., Cotter M.A., Cameron N.E. Autonomic neuropathy, corpus cavernosum innervation and endothelial responses: diabetic defects prevented by α-lipoic acid in rats. J. Peripheral Nerv. Syst. 2:1997;277.
    • (1997) J. Peripheral Nerv. Syst. , vol.2 , pp. 277
    • Keegan, A.1    Cotter, M.A.2    Cameron, N.E.3
  • 55
    • 0028845524 scopus 로고
    • Treatment of symptomatic diabetic peripheral neuropathy with the anti-oxidant α-lipoic acid. A 3-week multicentre randomized controlled trial (ALADIN Study)
    • Ziegler D., Hanefeld M., Ruhnau K.J. et al. Treatment of symptomatic diabetic peripheral neuropathy with the anti-oxidant α-lipoic acid. A 3-week multicentre randomized controlled trial (ALADIN Study). Diabetologia. 38:1995;1425-1433.
    • (1995) Diabetologia , vol.38 , pp. 1425-1433
    • Ziegler, D.1    Hanefeld, M.2    Ruhnau, K.J.3
  • 56
    • 0031028636 scopus 로고    scopus 로고
    • Effects of treatment with the antioxidant α-lipoic acid on cardiac autonomic neuropathy in NIDDM patients. A 4-month randomized controlled multicenter trial (DEKAN Study)
    • Ziegler D., Schatz H., Gries F.A., Ulrich H., Reichel G. Effects of treatment with the antioxidant α-lipoic acid on cardiac autonomic neuropathy in NIDDM patients. A 4-month randomized controlled multicenter trial (DEKAN Study). Diabetes Care. 20:1997;369-373.
    • (1997) Diabetes Care , vol.20 , pp. 369-373
    • Ziegler, D.1    Schatz, H.2    Gries, F.A.3    Ulrich, H.4    Reichel, G.5
  • 57
    • 0344338006 scopus 로고    scopus 로고
    • Metal chelator and free radical scavenger treatments prevent chronic aorta relaxation defects in diabetic rats
    • (Suppl. 1)
    • Keegan A., Cotter M.A., Archibald V., Cameron N.E. Metal chelator and free radical scavenger treatments prevent chronic aorta relaxation defects in diabetic rats. Diabetologia. 39:1996;A240. (Suppl. 1).
    • (1996) Diabetologia , vol.39 , pp. 240
    • Keegan, A.1    Cotter, M.A.2    Archibald, V.3    Cameron, N.E.4
  • 58
    • 0029004336 scopus 로고
    • Acetyl-L-carnitine corrects altered peripheral nerve function in experimental diabetes
    • Lowitt S., Malone J.I., Salem A.F., Korthals J., Benford S. Acetyl-L-carnitine corrects altered peripheral nerve function in experimental diabetes. Metabolism. 44:1995;677-680.
    • (1995) Metabolism , vol.44 , pp. 677-680
    • Lowitt, S.1    Malone, J.I.2    Salem, A.F.3    Korthals, J.4    Benford, S.5
  • 59
    • 0028286444 scopus 로고
    • Aldose reductase inhibition, nerve perfusion, oxygenation and function in streptozotocin-diabetic rats: Dose-response considerations and independence from a myoinositol mechanism
    • Cameron N.E., Cotter M.A., Dines K.C., Maxfield E.K., Carey F., Mirrlees D.J. Aldose reductase inhibition, nerve perfusion, oxygenation and function in streptozotocin-diabetic rats: dose-response considerations and independence from a myoinositol mechanism. Diabetologia. 37:1994;651-663.
    • (1994) Diabetologia , vol.37 , pp. 651-663
    • Cameron, N.E.1    Cotter, M.A.2    Dines, K.C.3    Maxfield, E.K.4    Carey, F.5    Mirrlees, D.J.6
  • 60
    • 0028965682 scopus 로고
    • Effect of a potent new aldose reductase inhibitor (5-(3-thienyl)tetrazol-1-yl)acetic acid (TAT), on diabetic neuropathy in rats
    • Hotta N., Kaskuta H., Fukasawa H. et al. Effect of a potent new aldose reductase inhibitor (5-(3-thienyl)tetrazol-1-yl)acetic acid (TAT), on diabetic neuropathy in rats. Diabetes Res. Clin. Pract. 27:1995;107-117.
    • (1995) Diabetes Res. Clin. Pract. , vol.27 , pp. 107-117
    • Hotta, N.1    Kaskuta, H.2    Fukasawa, H.3
  • 62
    • 0028223128 scopus 로고
    • Glycation, glycoxidation and cross-linking of collagen by glucose: Kinetics, mechanisms, and inhibition of late stages of the Maillard reaction
    • Fu M.X., Wells-Knecht K.J., Blackledge J.A. et al. Glycation, glycoxidation and cross-linking of collagen by glucose: kinetics, mechanisms, and inhibition of late stages of the Maillard reaction. Diabetes. 43:1994;676-683.
    • (1994) Diabetes , vol.43 , pp. 676-683
    • Fu, M.X.1    Wells-Knecht, K.J.2    Blackledge, J.A.3
  • 63
    • 0029759740 scopus 로고    scopus 로고
    • Rapid reversal by aminoguanidine of the neurovascular effects of diabetes in rats: Modulation by nitric oxide synthase inhibition
    • Cameron N.E., Cotter M.A. Rapid reversal by aminoguanidine of the neurovascular effects of diabetes in rats: modulation by nitric oxide synthase inhibition. Metabolism. 45:1996;1147-1152.
    • (1996) Metabolism , vol.45 , pp. 1147-1152
    • Cameron, N.E.1    Cotter, M.A.2
  • 64
    • 0030050234 scopus 로고    scopus 로고
    • Interactions between essential fatty acid, prostanoid, polyol pathway and nitric oxide mechanisms in the neurovascular deficit of diabetic rats
    • Cameron N.E., Cotter M.A., Hohman T.C. Interactions between essential fatty acid, prostanoid, polyol pathway and nitric oxide mechanisms in the neurovascular deficit of diabetic rats. Diabetologia. 39:1996;172-182.
    • (1996) Diabetologia , vol.39 , pp. 172-182
    • Cameron, N.E.1    Cotter, M.A.2    Hohman, T.C.3
  • 65
    • 0030928942 scopus 로고    scopus 로고
    • Effects of dietary supplementation with arachidonic acid rich oils on nerve conduction and blood flow in streptozotocin-diabetic rats
    • Cotter M.A., Cameron N.E. Effects of dietary supplementation with arachidonic acid rich oils on nerve conduction and blood flow in streptozotocin-diabetic rats. Prostaglandins Leukot. Essent. Fatty Acids. 56:1997;337-343.
    • (1997) Prostaglandins Leukot. Essent. Fatty Acids , vol.56 , pp. 337-343
    • Cotter, M.A.1    Cameron, N.E.2
  • 66
    • 0029848874 scopus 로고    scopus 로고
    • Interaction between oxidative stress and γ-linolenic acid in the impaired neurovascular function of diabetic rats
    • Cameron N.E., Cotter M.A. Interaction between oxidative stress and γ-linolenic acid in the impaired neurovascular function of diabetic rats. Am. J. Physiol. 271:1996;E471-E476.
    • (1996) Am. J. Physiol. , vol.271
    • Cameron, N.E.1    Cotter, M.A.2
  • 67
    • 0029845386 scopus 로고    scopus 로고
    • Comparison of the effects of ascorbyl γ-linolenic acid and γ-linolenic acid in the correction of neurovascular deficits in diabetic rats
    • Cameron N.E., Cotter M.A. Comparison of the effects of ascorbyl γ-linolenic acid and γ-linolenic acid in the correction of neurovascular deficits in diabetic rats. Diabetologia. 39:1996;1047-1054.
    • (1996) Diabetologia , vol.39 , pp. 1047-1054
    • Cameron, N.E.1    Cotter, M.A.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.