Suppression of the mTOR-raptor signaling pathway by the inhibitor of heat shock protein 90 geldanamycin

Journal of Biochemistry

Volumn 139, Issue 1, 2006, Pages 129-135

  Ohji, Goh ^a,b,c   Hidayat, Sujuti ^a,d   Nakashima, Akio ^a,b   Tokunaga, Chiharu ^a,b   Oshiro, Noriko ^a,b   Yoshino, Ken Ichi ^a,b   Yokono, Koichi ^c   Kikkawa, Ushio ^a,b   Yonezawa, Kazuyoshi ^a,b  

^a KOBE UNIVERSITY   (Japan)

^b JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

^c KOBE UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^d BRAWIJAYA UNIVERSITY   (Indonesia)

Author keywords

Geldanamycin; Hsp90; mTOR; Protein phosphorylation; Raptor

Indexed keywords

GELDANAMYCIN; HEAT SHOCK PROTEIN 90; INITIATION FACTOR 4E BINDING PROTEIN 1; MAMMALIAN TARGET OF RAPAMYCIN; PROTEIN S6; S6 KINASE;

AMINO ACID SEQUENCE; ARTICLE; CONTROLLED STUDY; DRUG INHIBITION; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; ENZYME REPRESSION; EPITOPE MAPPING; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; PROTEIN ANALYSIS; PROTEIN BINDING;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; AMINO ACID SEQUENCE; BENZOQUINONES; CELL LINE; ENZYME INHIBITORS; HSP90 HEAT-SHOCK PROTEINS; HUMANS; IMMUNOPRECIPITATION; LACTAMS, MACROCYCLIC; MOLECULAR SEQUENCE DATA; PHOSPHORYLATION; PROTEIN KINASES; PROTEINS; SIGNAL TRANSDUCTION; TOR SERINE-THREONINE KINASES;

EUKARYOTA; MAMMALIA; RAPTORES;

EID: 32944461766     PISSN: 0021924X     EISSN: None     Source Type: Journal    
DOI: 10.1093/jb/mvj008     Document Type: Article

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