Self-hydroxylation of taurine/α-ketoglutarate dioxygenase: Evidence for more than one oxygen activation mechanism

Journal of Biological Inorganic Chemistry

Volumn 11, Issue 1, 2006, Pages 63-72

  Koehntop, Kevin D ^a,d   Marimanikkuppam, Sudha ^c   Ryle, Matthew J ^b   Hausinger, Robert P ^b   Que Jr , Lawrence ^a  

^a University of Minnesota   (United States)

^b Michigan State University ^*  (United States)

^c UNIVERSITY OF MINNESOTA   (United States)

^d SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

Ketoglutarate dependent enzymes; 2 His 1 carboxylate facial triad; Non heme iron enzymes; Self hydroxylation; Taurine ketoglutarate dioxygenase

Indexed keywords

2 OXOGLUTARIC ACID; ACETALDEHYDE; BICARBONATE; CATECHOL DERIVATIVE; DIOXYGENASE; HEME; IRON; IRON COMPLEX; ISOTOPE; OXYGEN; OXYGEN 18; SUCCINIC ACID; SULFITE; TAURINE; TAURINE ALPHA KETOGLUTARATE DIOXYGENASE; TYROSINE; UNCLASSIFIED DRUG; WATER;

ARTICLE; CATALYSIS; CHROMATOPHORE; DECARBOXYLATION; ELECTRON TRANSPORT; ENZYME ACTIVE SITE; ENZYME MECHANISM; ENZYME SUBSTRATE; ENZYME SUBSTRATE COMPLEX; HYDROXYLATION; ISOTOPE LABELING; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; OXYGENATION; PARTICLE SIZE; PRIORITY JOURNAL; RAMAN SPECTROMETRY; SITE DIRECTED MUTAGENESIS;

BICARBONATES; BINDING SITES; CATECHOLS; FERRIC COMPOUNDS; FERROUS COMPOUNDS; GAS CHROMATOGRAPHY-MASS SPECTROMETRY; HISTIDINE; HYDROXYLATION; KETOGLUTARIC ACIDS; MIXED FUNCTION OXYGENASES; MUTAGENESIS; OXYGEN; SPECTRUM ANALYSIS, RAMAN; SUCCINIC ACID; TAURINE; TYROSINE;

EID: 29644433009     PISSN: 09498257     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00775-005-0059-4     Document Type: Article

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