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Journal of the American Chemical Society

Volumn 123, Issue 29, 2001, Pages 7017-7030

Rational reprogramming of the R2 subunit of Escherichia coli ribonucleotide reductase into a self-hydroxylating monooxygenase

(12) Baldwin, J a Voegtli, W C b Khidekel, N b Monne Loccoz P c Krebs, C d Pereira, A S d,e Ley, B A a Huynh, B H d Loehr, T M c Riggs Gelasco, P J f Rosenzweig, A C b Bollinger Jr , J M a

a PENNSYLVANIA STATE UNIVERSITY (United States)

b NORTHWESTERN UNIVERSITY (United States)

c OREGON HEALTH AND SCIENCE UNIVERSITY (United States)

d EMORY UNIVERSITY (United States)

e UNIVERSIDADE NOVA DE LISBOA (Portugal)

f School of Business (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DIIRON CLUSTER;

AMINO ACIDS; ENZYMES; HYDROXYLATION; IRON COMPOUNDS; OXYGEN; PROTEINS; RAMAN SCATTERING; SENSITIVITY ANALYSIS; X RAY CRYSTALLOGRAPHY;

ESCHERICHIA COLI;

ASPARTIC ACID; CARBOXYLIC ACID DERIVATIVE; GLUTAMINE; IRON DERIVATIVE; METHANE MONOOXYGENASE; PHENYLALANINE DERIVATIVE; RIBONUCLEOTIDE REDUCTASE; TYROSINE; UNSPECIFIC MONOOXYGENASE; DIAGNOSTIC AGENT; IRON; LIGAND; OXYGEN; OXYGENASE; RIBONUCLEOTIDE REDUCTASE R2 SUBUNIT;

AMINO ACID SUBSTITUTION; ARTICLE; ENZYME ANALYSIS; ENZYME SUBUNIT; ESCHERICHIA COLI; HYDROXYLATION; NONHUMAN; PHASE TRANSITION; RAMAN SPECTROMETRY; X RAY CRYSTALLOGRAPHY; CATALYSIS; CHEMISTRY; ENZYME ACTIVE SITE; ENZYMOLOGY; GENETICS; MOSSBAUER SPECTROSCOPY; SITE DIRECTED MUTAGENESIS; SPECTROSCOPY; X RAY;

AMINO ACID SUBSTITUTION; CATALYSIS; CATALYTIC DOMAIN; CRYSTALLOGRAPHY, X-RAY; ESCHERICHIA COLI; HYDROXYLATION; IRON; LIGANDS; MUTAGENESIS, SITE-DIRECTED; OXYGEN ISOTOPES; OXYGENASES; RIBONUCLEOTIDE REDUCTASES; SPECTROSCOPY, MOSSBAUER; SPECTRUM ANALYSIS; SPECTRUM ANALYSIS, RAMAN; X-RAYS;

EID: 0034741608 PISSN: 00027863 EISSN: None Source Type: Journal
DOI: 10.1021/ja002114g Document Type: Article

Times cited : (72)

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