Evidence for Hydrogen Abstraction from C1 of Taurine by the High-Spin Fe(IV) Intermediate Detected during Oxygen Activation by Taurine:α -Ketoglutarate Dioxygenase (TauD)

Journal of the American Chemical Society

Volumn 125, Issue 43, 2003, Pages 13008-13009

  Price, John C ^a   Barr, Eric W ^a   Glass, Timothy E ^a,b   Krebs, Carsten ^a   Bollinger Jr , J Martin ^a  

^a PENNSYLVANIA STATE UNIVERSITY   (United States)

^b UNIVERSITY OF MISSOURI   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2 OXOGLUTARIC ACID; ALPHA KETOGLUTARATE DIOXYGENASE; CARBON; GLUTARIC ACID DERIVATIVE; HYDROGEN; IRON; TAURINE; UNCLASSIFIED DRUG;

ABSORPTION SPECTROSCOPY; ACCELERATION; ARTICLE; CHEMICAL ANALYSIS; CHEMICAL REACTION KINETICS; HYDROXYLATION;

DEUTERIUM EXCHANGE MEASUREMENT; ESCHERICHIA COLI; FERROUS COMPOUNDS; HYDROGEN; KINETICS; MIXED FUNCTION OXYGENASES; OXYGEN; SPECTROSCOPY, MOSSBAUER; TAURINE;

EID: 0142183453     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja037400h     Document Type: Article

References (10)

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5. -1. In addition, the mechanism presented previously contained no error estimates, whereas the additional experiments conducted in this work have allowed error limits to be estimated.
6. The synthetic procedures will be described elsewhere; characterization of the synthetic substrates is provided in the Supporting Information.
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9. The assay for sulfite production has been described.4 14CO2 release was measured by a procedure derived from that reported by Jones et al. (ref 10). The modified procedure is described in the Supporting Information.
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