An Hfe-dependent pathway mediates hyposideremia in response to lipopolysaccharide-induced inflammation in mice

Nature Genetics

Volumn 36, Issue 5, 2004, Pages 481-485

  Roy, Cindy N ^a,b   Custodio, Ángel O ^a,b   De Graaf, Jos ^c   Schneider, Susanne ^c   Akpan, Imo ^a,d   Montross, Lynne K ^a,b,d   Sanchez, Mayka ^c   Gaudino, Alessandro ^c   Hentze, Matthias W ^c   Andrews, Nancy C ^a,b,d   Muckenthaler, Martina U ^c,e  

^a BOSTON CHILDREN S HOSPITAL   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

^c EUROPEAN MOLECULAR BIOLOGY LABORATORY   (Germany)

^d HOWARD HUGHES MEDICAL INSTITUTE   (United States)

^e UNIVERSITY OF HEIDELBERG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

DEFENSIN; GENE PRODUCT; HEPCIDIN; HFE PROTEIN; IRON; LIPOPOLYSACCHARIDE; PEPTIDE HORMONE;

ACUTE PHASE RESPONSE; ANEMIA; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CLINICAL FEATURE; CONTROLLED STUDY; ERYTHROCYTE; FEMALE; HEMOCHROMATOSIS; HEMOSIDEROSIS; HYPOSIDEROSIS; IMMUNITY; INFECTION RESISTANCE; INFLAMMATION; IRON ABSORPTION; IRON BALANCE; IRON BLOOD LEVEL; IRON STORAGE; MACROPHAGE; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL;

ANEMIA, HYPOCHROMIC; ANIMALS; ANTIMICROBIAL CATIONIC PEPTIDES; GENE EXPRESSION PROFILING; HEMOCHROMATOSIS; HISTOCOMPATIBILITY ANTIGENS CLASS I; INFLAMMATION; IRON; LIPOPOLYSACCHARIDES; MEMBRANE PROTEINS; MICE; MICE, KNOCKOUT; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SIGNAL TRANSDUCTION;

ANIMALIA;

EID: 2442426523     PISSN: 10614036     EISSN: None     Source Type: Journal    
DOI: 10.1038/ng1350     Document Type: Article

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