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Volumn 4, Issue 4, 2005, Pages 301-314

Multifocal angiostatic therapy: An update

Author keywords

Angiogenesis; Diindolylmethane; EGCG; Nutraceuticals; Silymarin

Indexed keywords

ACETYLSALICYLIC ACID; CHEMOKINE RECEPTOR CXCR4; COMBRETASTATIN; CYCLOOXYGENASE 2; DIINDOLYLMETHANE; EPIDERMAL GROWTH FACTOR RECEPTOR 2; FISH OIL; GLYCINE; HEAT SHOCK PROTEIN 90; I KAPPA B KINASE INHIBITOR; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MAMMALIAN TARGET OF RAPAMYCIN; METHANE; NUTRACEUTICAL; POLYPHENOL DERIVATIVE; PROTEIN FARNESYLTRANSFERASE; PROTEIN TYROSINE KINASE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; SALICYLIC ACID; SALICYLIC ACID DERIVATIVE; SELENIUM; SILIBININ; SILYMARIN; STAT3 PROTEIN; SULINDAC; TETRATHIOMOLYBDIC ACID; THALIDOMIDE; THIOREDOXIN REDUCTASE; UNCLASSIFIED DRUG; UNINDEXED DRUG; VASCULOTROPIN RECEPTOR 2;

EID: 28144449108     PISSN: 15347354     EISSN: None     Source Type: Journal    
DOI: 10.1177/1534735405282475     Document Type: Review
Times cited : (16)

References (166)
  • 1
    • 0037663768 scopus 로고    scopus 로고
    • A wholly nutritional "multifocal angiostatic therapy" for control of disseminated cancer
    • McCarty MF. A wholly nutritional "multifocal angiostatic therapy" for control of disseminated cancer. Med Hypotheses. 2003;61:1-15.
    • (2003) Med Hypotheses , vol.61 , pp. 1-15
    • McCarty, M.F.1
  • 2
    • 0038402729 scopus 로고    scopus 로고
    • Indole-3-carbinol and 3,3′-diindolylmethane induce apoptosis in human prostate cancer cells
    • Nachshon-Kedmi M, Yannai S, Haj A, Fares FA. Indole-3-carbinol and 3,3′-diindolylmethane induce apoptosis in human prostate cancer cells. Food Chem Toxicol. 2003;41:745-752.
    • (2003) Food Chem Toxicol , vol.41 , pp. 745-752
    • Nachshon-Kedmi, M.1    Yannai, S.2    Haj, A.3    Fares, F.A.4
  • 4
    • 0036240975 scopus 로고    scopus 로고
    • Estrogen metabolism and the diet-cancer connection: Rationale for assessing the ratio of urinary hydroxylated estrogen metabolites
    • Lord RS, Bongiovanni B, Bralley JA. Estrogen metabolism and the diet-cancer connection: rationale for assessing the ratio of urinary hydroxylated estrogen metabolites. Altern Med Rev. 2002;7:112-129.
    • (2002) Altern Med Rev , vol.7 , pp. 112-129
    • Lord, R.S.1    Bongiovanni, B.2    Bralley, J.A.3
  • 5
    • 0031715037 scopus 로고    scopus 로고
    • Aryl hydrocarbon receptor-mediated antiestrogenic and antitumorigenic activity of diindolylmethane
    • Chen I, McDougal A, Wang F, Safe S. Aryl hydrocarbon receptor-mediated antiestrogenic and antitumorigenic activity of diindolylmethane. Carcinogenesis. 1998;19:1631-1639.
    • (1998) Carcinogenesis , vol.19 , pp. 1631-1639
    • Chen, I.1    McDougal, A.2    Wang, F.3    Safe, S.4
  • 6
    • 4544358789 scopus 로고    scopus 로고
    • Therapeutic activity of 3,3′-diindolylmethane on prostate cancer in an in vivo model
    • Nachshon-Kedmi M, Fares FA, Yannai S. Therapeutic activity of 3,3′-diindolylmethane on prostate cancer in an in vivo model. Prostate. 2004;61:153-160.
    • (2004) Prostate , vol.61 , pp. 153-160
    • Nachshon-Kedmi, M.1    Fares, F.A.2    Yannai, S.3
  • 7
    • 17844381889 scopus 로고    scopus 로고
    • 3,3′-Diindolylmethane inhibits angiogenesis and the growth of transplantable human breast carcinoma in athymic mice
    • Chang X, Tou JC, Hong C, et al. 3,3′-Diindolylmethane inhibits angiogenesis and the growth of transplantable human breast carcinoma in athymic mice. Carcinogenesis. 2005;26:771-778.
    • (2005) Carcinogenesis , vol.26 , pp. 771-778
    • Chang, X.1    Tou, J.C.2    Hong, C.3
  • 9
    • 0035208658 scopus 로고    scopus 로고
    • Indole-3-carbinol and diindolylmethane induce apoptosis of human cervical cancer cells and in murine HPV16-transgenic preneoplastic cervical epithelium
    • Chen DZ, Qi M, Auborn KJ, Carter TH. Indole-3-carbinol and diindolylmethane induce apoptosis of human cervical cancer cells and in murine HPV16-transgenic preneoplastic cervical epithelium. J Nutr. 2001;131:3294-3302.
    • (2001) J Nutr , vol.131 , pp. 3294-3302
    • Chen, D.Z.1    Qi, M.2    Auborn, K.J.3    Carter, T.H.4
  • 10
    • 0037087501 scopus 로고    scopus 로고
    • Bcl-2 family-mediated apoptotic effects of 3,3′-diindolylmethane (DIM) in human breast cancer cells
    • Hong C, Firestone GL, Bjeldanes LF. Bcl-2 family-mediated apoptotic effects of 3,3′-diindolylmethane (DIM) in human breast cancer cells. Biochem Pharmacol. 2002;63:1085-1097.
    • (2002) Biochem Pharmacol , vol.63 , pp. 1085-1097
    • Hong, C.1    Firestone, G.L.2    Bjeldanes, L.F.3
  • 11
    • 0038402729 scopus 로고    scopus 로고
    • Indole-3-carbinol and 3,3′-diindolylmethane induce apoptosis in human prostate cancer cells
    • Nachshon-Kedmi M, Yannai S, Haj A, Fares FA. Indole-3-carbinol and 3,3′-diindolylmethane induce apoptosis in human prostate cancer cells. Food Chem Toxicol. 2003;41:745-752.
    • (2003) Food Chem Toxicol , vol.41 , pp. 745-752
    • Nachshon-Kedmi, M.1    Yannai, S.2    Haj, A.3    Fares, F.A.4
  • 12
    • 0035211762 scopus 로고    scopus 로고
    • The use of silymarin in the treatment of liver diseases
    • Saller R, Meier R, Brignoli R. The use of silymarin in the treatment of liver diseases. Drugs. 2001;61:2035-2063.
    • (2001) Drugs , vol.61 , pp. 2035-2063
    • Saller, R.1    Meier, R.2    Brignoli, R.3
  • 13
    • 0036210452 scopus 로고    scopus 로고
    • Silymarin inhibits growth and causes regression of established skin tumors in SENCAR mice via modulation of mitogen-activated protein kinases and induction of apoptosis
    • Singh RP, Tyagi AK, Zhao J, Agarwal R. Silymarin inhibits growth and causes regression of established skin tumors in SENCAR mice via modulation of mitogen-activated protein kinases and induction of apoptosis. Carcinogenesis. 2002;23:499-510.
    • (2002) Carcinogenesis , vol.23 , pp. 499-510
    • Singh, R.P.1    Tyagi, A.K.2    Zhao, J.3    Agarwal, R.4
  • 14
    • 0036606413 scopus 로고    scopus 로고
    • Dietary feeding of silibinin inhibits advance human prostate carcinoma growth in athymic nude mice and increases plasma insulin-like growth factor-binding protein-3 levels
    • Singh RP, Dhanalakshmi S, Tyagi AK, Chan DC, Agarwal C, Agarwal R. Dietary feeding of silibinin inhibits advance human prostate carcinoma growth in athymic nude mice and increases plasma insulin-like growth factor-binding protein-3 levels. Cancer Res. 2002;62:3063-3069.
    • (2002) Cancer Res , vol.62 , pp. 3063-3069
    • Singh, R.P.1    Dhanalakshmi, S.2    Tyagi, A.K.3    Chan, D.C.4    Agarwal, C.5    Agarwal, R.6
  • 15
    • 0035868975 scopus 로고    scopus 로고
    • Phase I trial of oral green tea extract in adult patients with solid tumors
    • Pisters KM, Newman RA, Goldman B, et al. Phase I trial of oral green tea extract in adult patients with solid tumors. J Clin Oncol. 2001;19:1830-1838.
    • (2001) J Clin Oncol , vol.19 , pp. 1830-1838
    • Pisters, K.M.1    Newman, R.A.2    Goldman, B.3
  • 16
    • 0042334847 scopus 로고    scopus 로고
    • Pharmacokinetics and safety of green tea polyphenols after multiple-dose administration of epigallocatechin gallate and polyphenon e in healthy individuals
    • Chow HH, Cai Y, Hakim IA, et al. Pharmacokinetics and safety of green tea polyphenols after multiple-dose administration of epigallocatechin gallate and polyphenon E in healthy individuals. Clin Cancer Res. 2003;9:3312-3319.
    • (2003) Clin Cancer Res , vol.9 , pp. 3312-3319
    • Chow, H.H.1    Cai, Y.2    Hakim, I.A.3
  • 17
    • 0036606413 scopus 로고    scopus 로고
    • Dietary feeding of silibinin inhibits advance human prostate carcinoma growth in athymic nude mice and increases plasma insulin-like growth factor-binding protein-3 levels
    • Singh RP, Dhanalakshmi S, Tyagi AK, Chan DC, Agarwal C, Agarwal R. Dietary feeding of silibinin inhibits advance human prostate carcinoma growth in athymic nude mice and increases plasma insulin-like growth factor-binding protein-3 levels. Cancer Res. 2002;62:3063-3069.
    • (2002) Cancer Res , vol.62 , pp. 3063-3069
    • Singh, R.P.1    Dhanalakshmi, S.2    Tyagi, A.K.3    Chan, D.C.4    Agarwal, C.5    Agarwal, R.6
  • 18
    • 11144222544 scopus 로고    scopus 로고
    • Oral silibinin inhibits lung tumor growth in athymic nude mice and forms a novel chemocombination with doxorubicin targeting nuclear factor kappaB-mediated inducible chemoresistance
    • Singh RP, Mallikarjuna GU, Sharma G, et al. Oral silibinin inhibits lung tumor growth in athymic nude mice and forms a novel chemocombination with doxorubicin targeting nuclear factor kappaB-mediated inducible chemoresistance. Clin Cancer Res. 2004;10:8641-8647.
    • (2004) Clin Cancer Res , vol.10 , pp. 8641-8647
    • Singh, R.P.1    Mallikarjuna, G.U.2    Sharma, G.3
  • 19
    • 0036210452 scopus 로고    scopus 로고
    • Silymarin inhibits growth and causes regression of established skin tumors in SENCAR mice via modulation of mitogen-activated protein kinases and induction of apoptosis
    • Singh RP, Tyagi AK, Zhao J, Agarwal R. Silymarin inhibits growth and causes regression of established skin tumors in SENCAR mice via modulation of mitogen-activated protein kinases and induction of apoptosis. Carcinogenesis. 2002;23:499-510.
    • (2002) Carcinogenesis , vol.23 , pp. 499-510
    • Singh, R.P.1    Tyagi, A.K.2    Zhao, J.3    Agarwal, R.4
  • 20
    • 0033594891 scopus 로고    scopus 로고
    • Silibinin decreases prostate-specific antigen with cell growth inhibition via G1 arrest, leading to differentiation of prostate carcinoma cells: Implications for prostate cancer intervention
    • Zi X, Agarwal R. Silibinin decreases prostate-specific antigen with cell growth inhibition via G1 arrest, leading to differentiation of prostate carcinoma cells: implications for prostate cancer intervention. Proc Natl Acad Sci U S A. 1999;96:7490-7495.
    • (1999) Proc Natl Acad Sci U S A , vol.96 , pp. 7490-7495
    • Zi, X.1    Agarwal, R.2
  • 21
    • 0036843213 scopus 로고    scopus 로고
    • Antiproliferative and apoptotic effects of silibinin in rat prostate cancer cells
    • Tyagi A, Bhatia N, Condon MS, Bosland MC, Agarwal C, Agarwal R. Antiproliferative and apoptotic effects of silibinin in rat prostate cancer cells. Prostate. 2002;53:211-217.
    • (2002) Prostate , vol.53 , pp. 211-217
    • Tyagi, A.1    Bhatia, N.2    Condon, M.S.3    Bosland, M.C.4    Agarwal, C.5    Agarwal, R.6
  • 22
    • 0036847718 scopus 로고    scopus 로고
    • Silibinin strongly synergizes human prostate carcinoma DU145 cells to doxorubicin-incluced growth inhibition, G2-M arrest, and apoptosis
    • Tyagi AK, Singh RP, Agarwal C, Chan DC, Agarwal R. Silibinin strongly synergizes human prostate carcinoma DU145 cells to doxorubicin-incluced growth inhibition, G2-M arrest, and apoptosis. Clin Cancer Res. 2002;8:3512-3519.
    • (2002) Clin Cancer Res , vol.8 , pp. 3512-3519
    • Tyagi, A.K.1    Singh, R.P.2    Agarwal, C.3    Chan, D.C.4    Agarwal, R.5
  • 23
    • 0043025262 scopus 로고    scopus 로고
    • Silibinin sensitizes human prostate carcinoma DU145 cells to cisplatin-and carboplatin-induced growth inhibition and apoptotic death
    • Dhanalakshmi S, Agarwal P, Glode LM, Agarwal R. Silibinin sensitizes human prostate carcinoma DU145 cells to cisplatin-and carboplatin-induced growth inhibition and apoptotic death. Int J Cancer. 2003;106:699-705.
    • (2003) Int J Cancer , vol.106 , pp. 699-705
    • Dhanalakshmi, S.1    Agarwal, P.2    Glode, L.M.3    Agarwal, R.4
  • 24
    • 0042807487 scopus 로고    scopus 로고
    • Silibinin induces growth inhibition and apoptotic cell death in human lung carcinoma cells
    • Sharma G, Singh RP, Chan DC, Agarwal R. Silibinin induces growth inhibition and apoptotic cell death in human lung carcinoma cells. Anticancer Res. 2003;23:2649-2655.
    • (2003) Anticancer Res , vol.23 , pp. 2649-2655
    • Sharma, G.1    Singh, R.P.2    Chan, D.C.3    Agarwal, R.4
  • 25
    • 0344827261 scopus 로고    scopus 로고
    • Silibinin upregulates the expression of cyclin-dependent kinase inhibitors and causes cell cycle arrest and apoptosis in human colon carcinoma HT-29 cells
    • Agarwal C, Singh RP, Dhanalakshmi S, et al. Silibinin upregulates the expression of cyclin-dependent kinase inhibitors and causes cell cycle arrest and apoptosis in human colon carcinoma HT-29 cells. Oncogene. 2003;22:8271-8282.
    • (2003) Oncogene , vol.22 , pp. 8271-8282
    • Agarwal, C.1    Singh, R.P.2    Dhanalakshmi, S.3
  • 26
    • 0344495296 scopus 로고    scopus 로고
    • Silibinin down-regulates survivin protein and mRNA expression and causes caspases activation and apoptosis in human bladder transitional-cell papilloma RT4 cells
    • Tyagi AK, Agarwal C, Singh RP, Shroyer KR, Glode LM, Agarwal R. Silibinin down-regulates survivin protein and mRNA expression and causes caspases activation and apoptosis in human bladder transitional-cell papilloma RT4 cells. Biochem Biophys Res Commun. 2003;312:1178-1184.
    • (2003) Biochem Biophys Res Commun , vol.312 , pp. 1178-1184
    • Tyagi, A.K.1    Agarwal, C.2    Singh, R.P.3    Shroyer, K.R.4    Glode, L.M.5    Agarwal, R.6
  • 27
    • 3242786628 scopus 로고    scopus 로고
    • Synergistic anti-cancer effects of silibinin with conventional cytotoxic agents doxorubicin, cisplatin and carboplatin against human breast carcinoma MCF-7 and MDA-MB468 cells
    • Tyagi AK, Agarwal C, Chan DC, Agarwal R. Synergistic anti-cancer effects of silibinin with conventional cytotoxic agents doxorubicin, cisplatin and carboplatin against human breast carcinoma MCF-7 and MDA-MB468 cells. Oncol Rep. 2004;11:493-499.
    • (2004) Oncol Rep , vol.11 , pp. 493-499
    • Tyagi, A.K.1    Agarwal, C.2    Chan, D.C.3    Agarwal, R.4
  • 28
    • 4544287556 scopus 로고    scopus 로고
    • Silibinin causes cell cycle arrest and apoptosis in human bladder transitional cell carcinoma cells by regulating CDKI-CDK-cyclin cascade, and caspase 3 and PARP cleavages
    • Tyagi A, Agarwal C, Harrison G, Glode LM, Agarwal R. Silibinin causes cell cycle arrest and apoptosis in human bladder transitional cell carcinoma cells by regulating CDKI-CDK-cyclin cascade, and caspase 3 and PARP cleavages. Carcinogenesis. 2004;25:1711-1720.
    • (2004) Carcinogenesis , vol.25 , pp. 1711-1720
    • Tyagi, A.1    Agarwal, C.2    Harrison, G.3    Glode, L.M.4    Agarwal, R.5
  • 29
    • 5144224381 scopus 로고    scopus 로고
    • A cancer chemopreventive agent silibinin, targets mitogenic and survival signaling in prostate cancer
    • Singh RP, Agarwal R. A cancer chemopreventive agent silibinin, targets mitogenic and survival signaling in prostate cancer. Mutat Res. 2004;555:21-32.
    • (2004) Mutat Res , vol.555 , pp. 21-32
    • Singh, R.P.1    Agarwal, R.2
  • 30
    • 0032573394 scopus 로고    scopus 로고
    • Selective inhibition of NF-kappaB activation by the flavonoid hepatoprotector silymarin in HepG2: Evidence for different activating pathways
    • Saliou C, Rihn B, Cillard J, Okamoto T, Packer L. Selective inhibition of NF-kappaB activation by the flavonoid hepatoprotector silymarin in HepG2: evidence for different activating pathways. FEBS Lett. 1998;440:8-12.
    • (1998) FEBS Lett , vol.440 , pp. 8-12
    • Saliou, C.1    Rihn, B.2    Cillard, J.3    Okamoto, T.4    Packer, L.5
  • 31
    • 0037034863 scopus 로고    scopus 로고
    • Silibinin inhibits constitutive and TNFalpha-induced activation of NF-kappaB and sensitizes human prostate carcinoma DU145 cells to TNFalpha-induced apoptosis
    • Dhanalakshmi S, Singh RP, Agarwal C, Agarwal R. Silibinin inhibits constitutive and TNFalpha-induced activation of NF-kappaB and sensitizes human prostate carcinoma DU145 cells to TNFalpha-induced apoptosis. Oncogone. 2002;21:1759-1767.
    • (2002) Oncogone , vol.21 , pp. 1759-1767
    • Dhanalakshmi, S.1    Singh, R.P.2    Agarwal, C.3    Agarwal, R.4
  • 32
    • 1542438807 scopus 로고    scopus 로고
    • Involvement of NF-kappaB and caspases in silibinin-induced apoptosis of endothelial cells
    • Yoo HG, Jung SN, Hwang YS, et al. Involvement of NF-kappaB and caspases in silibinin-induced apoptosis of endothelial cells. Int J Mol Med. 2004;13:81-86.
    • (2004) Int J Mol Med , vol.13 , pp. 81-86
    • Yoo, H.G.1    Jung, S.N.2    Hwang, Y.S.3
  • 33
    • 0034675269 scopus 로고    scopus 로고
    • Anti-angiogenic potential of acancer chemopreventive flavonoid antioxidant, silymarin: Inhibition of key attributes of vascular endothelial cells and angiogenic cytokine secretion by cancer epithelial cells
    • Jiang C, Agarwal R, Lu J. Anti-angiogenic potential of acancer chemopreventive flavonoid antioxidant, silymarin: inhibition of key attributes of vascular endothelial cells and angiogenic cytokine secretion by cancer epithelial cells. Biochem Biophys Res Commun. 2000;276:371-378.
    • (2000) Biochem Biophys Res Commun , vol.276 , pp. 371-378
    • Jiang, C.1    Agarwal, R.2    Lu, J.3
  • 34
    • 0141786950 scopus 로고    scopus 로고
    • Suppression of advanced human prostate tumor growth in athymic mice by silibinin feeding is associated with reduced cell proliferation, increased apoptosis, and inhibition of angiogenesis
    • Singh RP, Sharma G, Dhanalakshmi S, Agarwal C, Agarwal R. Suppression of advanced human prostate tumor growth in athymic mice by silibinin feeding is associated with reduced cell proliferation, increased apoptosis, and inhibition of angiogenesis. Cancer Epidemiol Biomarkers Prev. 2003;12:933-939.
    • (2003) Cancer Epidemiol Biomarkers Prev , vol.12 , pp. 933-939
    • Singh, R.P.1    Sharma, G.2    Dhanalakshmi, S.3    Agarwal, C.4    Agarwal, R.5
  • 35
    • 0042736063 scopus 로고    scopus 로고
    • Anti-angiogenic effect of silymarin on colon cancer LoVo cell line
    • Yang SH, Lin JK, Chen WS, Chiu JH. Anti-angiogenic effect of silymarin on colon cancer LoVo cell line. J Surg Res. 2003;113:133-138.
    • (2003) J Surg Res , vol.113 , pp. 133-138
    • Yang, S.H.1    Lin, J.K.2    Chen, W.S.3    Chiu, J.H.4
  • 36
    • 23944519382 scopus 로고    scopus 로고
    • Silibinin inhibits angiogenesis via Flt-1, but not KDR, receptor up-regulation
    • Yang SH, Lin JK, Huang CJ, Chen WS, Li SY, Chiu JH. Silibinin inhibits angiogenesis via Flt-1, but not KDR, receptor up-regulation. J Surg Res. 2005;128:140-146.
    • (2005) J Surg Res , vol.128 , pp. 140-146
    • Yang, S.H.1    Lin, J.K.2    Huang, C.J.3    Chen, W.S.4    Li, S.Y.5    Chiu, J.H.6
  • 37
    • 0141786950 scopus 로고    scopus 로고
    • Suppression of advanced human prostate tumor growth in athymic mice by silibinin feeding is associated with reduced cell proliferation, increased apoptosis, and inhibition of angiogenesis
    • Singh RP, Sharma G, Dhanalakshmi S, Agarwal C, Agarwal R. Suppression of advanced human prostate tumor growth in athymic mice by silibinin feeding is associated with reduced cell proliferation, increased apoptosis, and inhibition of angiogenesis. Cancer Epidemiol Biomarkers Prev. 2003;12:933-939.
    • (2003) Cancer Epidemiol Biomarkers Prev , vol.12 , pp. 933-939
    • Singh, R.P.1    Sharma, G.2    Dhanalakshmi, S.3    Agarwal, C.4    Agarwal, R.5
  • 38
    • 0034675269 scopus 로고    scopus 로고
    • Anti-angiogenic potential of a cancer chemopreventive flavonoid antioxidant, silymarin: Inhibition of key attributes of vascular endothelial cells and angiogenic cytokine secretion by cancer epithelial cells
    • Jiang C, Agarwal R, Lu J. Anti-angiogenic potential of a cancer chemopreventive flavonoid antioxidant, silymarin: inhibition of key attributes of vascular endothelial cells and angiogenic cytokine secretion by cancer epithelial cells. Biochem Biophys Res Commun. 2000;276:371-378.
    • (2000) Biochem Biophys Res Commun , vol.276 , pp. 371-378
    • Jiang, C.1    Agarwal, R.2    Lu, J.3
  • 39
    • 14644410403 scopus 로고    scopus 로고
    • Silibinin strongly inhibits growth and survival of human endothelial cells via cell cycle arrest and down regulation of survivin, Akt and NF-kappaB: Implications for angioprevention and antiangiogenic therapy
    • Singh RP, Dhanalakshmi S, Agarwal C, Agarwal R. Silibinin strongly inhibits growth and survival of human endothelial cells via cell cycle arrest and down regulation of survivin, Akt and NF-kappaB: implications for angioprevention and antiangiogenic therapy. Oncogene. 2005;24:1188-1202.
    • (2005) Oncogene , vol.24 , pp. 1188-1202
    • Singh, R.P.1    Dhanalakshmi, S.2    Agarwal, C.3    Agarwal, R.4
  • 40
    • 0032482978 scopus 로고    scopus 로고
    • Flt-1 lacking the tyrosine kinase domain is sufficient for normal development and angiogenesis in mice
    • Hiratsuka S, Minowa O, Kuno J, Noda T, Shibuya M. Flt-1 lacking the tyrosine kinase domain is sufficient for normal development and angiogenesis in mice. Proc Natl Acad Sci U S A. 1998;95:9349-9354.
    • (1998) Proc Natl Acad Sci U S A , vol.95 , pp. 9349-9354
    • Hiratsuka, S.1    Minowa, O.2    Kuno, J.3    Noda, T.4    Shibuya, M.5
  • 41
    • 0031824862 scopus 로고    scopus 로고
    • Eicosapentaenoic acid attenuates vascular endothelial growth factor-induced proliferation via inhibiting Flk-1 receptor expression in bovine carotid artery endothelial cells
    • Yang SP, Morita I, Murota SI. Eicosapentaenoic acid attenuates vascular endothelial growth factor-induced proliferation via inhibiting Flk-1 receptor expression in bovine carotid artery endothelial cells. J Cell Physiol. 1998;176:342-349.
    • (1998) J Cell Physiol , vol.176 , pp. 342-349
    • Yang, S.P.1    Morita, I.2    Murota, S.I.3
  • 42
    • 0025645646 scopus 로고
    • Pharmacokinetic studies on IdB 1016, a silybin-phosphatidylcholine complex, in healthy human subjects
    • Barzaghi N, Crema F, Gatti G, Pifferi G, Perucca E. Pharmacokinetic studies on IdB 1016, a silybin-phosphatidylcholine complex, in healthy human subjects. Eur J Drug Metab Pharmacokinet. 1990;15:333-338.
    • (1990) Eur J Drug Metab Pharmacokinet , vol.15 , pp. 333-338
    • Barzaghi, N.1    Crema, F.2    Gatti, G.3    Pifferi, G.4    Perucca, E.5
  • 43
    • 0347503514 scopus 로고    scopus 로고
    • Comparative bioavailability of silibinin in healthy male volunteers
    • Kim YC, Kim EJ, Lee ED, et al. Comparative bioavailability of silibinin in healthy male volunteers. InI J Clin Pharmacol Ther. 2003;41:593-596.
    • (2003) InI J Clin Pharmacol Ther , vol.41 , pp. 593-596
    • Kim, Y.C.1    Kim, E.J.2    Lee, E.D.3
  • 44
    • 0037081274 scopus 로고    scopus 로고
    • Green teacatechins inhibit vascular endothelial growth factor receptor phosphorylation
    • Lamy S, Gingras D, Beliveau R. Green teacatechins inhibit vascular endothelial growth factor receptor phosphorylation. Cancer Res. 2002;62:381-385.
    • (2002) Cancer Res , vol.62 , pp. 381-385
    • Lamy, S.1    Gingras, D.2    Beliveau, R.3
  • 45
    • 3242703539 scopus 로고    scopus 로고
    • VEGF receptor phosphorylation status and apoptosis is modulated by a green tea component, epigallocatechin-3-gallate (EGCG), in B-cell chronic lymphocytic leukemia
    • Lee YK, Bone ND, Strege AK, Shanafelt TD, Jelinek DF, Kay NE. VEGF receptor phosphorylation status and apoptosis is modulated by a green tea component, epigallocatechin-3-gallate (EGCG), in B-cell chronic lymphocytic leukemia. Blood. 2004;104:788-794.
    • (2004) Blood , vol.104 , pp. 788-794
    • Lee, Y.K.1    Bone, N.D.2    Strege, A.K.3    Shanafelt, T.D.4    Jelinek, D.F.5    Kay, N.E.6
  • 46
    • 0033118504 scopus 로고    scopus 로고
    • Angiogenesis inhibited by drinking tea
    • Cao Y, Cao R. Angiogenesis inhibited by drinking tea. Nature. 1999;398:381.
    • (1999) Nature , vol.398 , pp. 381
    • Cao, Y.1    Cao, R.2
  • 47
    • 0026469016 scopus 로고
    • Inhibitory effect of green tea on the growth of established skin papillomas in mice
    • Wang ZY, Huang MT, Ho CT, et al. Inhibitory effect of green tea on the growth of established skin papillomas in mice. Cancer Res. 1992;52:6657-6665.
    • (1992) Cancer Res , vol.52 , pp. 6657-6665
    • Wang, Z.Y.1    Huang, M.T.2    Ho, C.T.3
  • 49
    • 0033859756 scopus 로고    scopus 로고
    • Inhibition of angiogenesis and induction of endothelial and tumor cell apoptosis by green tea in animal models of human high-grade non-Hodgkin's lymphoma
    • Bertolini F, Fusetti L, Rabascio C, Cinieri S, Martinelli G, Pruned G. Inhibition of angiogenesis and induction of endothelial and tumor cell apoptosis by green tea in animal models of human high-grade non-Hodgkin's lymphoma. Leukemia. 2000;14:1477-1482.
    • (2000) Leukemia , vol.14 , pp. 1477-1482
    • Bertolini, F.1    Fusetti, L.2    Rabascio, C.3    Cinieri, S.4    Martinelli, G.5    Pruned, G.6
  • 52
    • 0035868975 scopus 로고    scopus 로고
    • Phase I trial of oral green tea extract in adult patients with solid tumors
    • Pisters KM, Newman RA, Coldman B, et al. Phase I trial of oral green tea extract in adult patients with solid tumors. J Clin Oncol. 2001;19:1830-1838.
    • (2001) J Clin Oncol , vol.19 , pp. 1830-1838
    • Pisters, K.M.1    Newman, R.A.2    Coldman, B.3
  • 53
    • 0037443797 scopus 로고    scopus 로고
    • A phase II trial of green tea in the treatment of patients with androgen independent metastatic prostate carcinoma
    • Jatoi A, Ellison N, Burch PA, et al. A phase II trial of green tea in the treatment of patients with androgen independent metastatic prostate carcinoma. Cancer. 2003;97:1442-1446.
    • (2003) Cancer , vol.97 , pp. 1442-1446
    • Jatoi, A.1    Ellison, N.2    Burch, P.A.3
  • 55
    • 0036733754 scopus 로고    scopus 로고
    • Copper deficiency induced by tetrathiomolybdate suppresses tumor growth and angiogenesis
    • Pan Q, Kleer CG, van Golen KL, et al. Copper deficiency induced by tetrathiomolybdate suppresses tumor growth and angiogenesis. Cancer Res. 2002;62:4854-4859.
    • (2002) Cancer Res , vol.62 , pp. 4854-4859
    • Pan, Q.1    Kleer, C.G.2    Van Golen, K.L.3
  • 56
    • 0041928194 scopus 로고    scopus 로고
    • Tetrathiomolybdate inhibits angiogenesis and metastasis through suppression of the NFkappaB signaling cascade
    • Pan Q, Bao LW, Merajver SD. Tetrathiomolybdate inhibits angiogenesis and metastasis through suppression of the NFkappaB signaling cascade. Mol Cancer Res. 2003;1:701-706.
    • (2003) Mol Cancer Res , vol.1 , pp. 701-706
    • Pan, Q.1    Bao, L.W.2    Merajver, S.D.3
  • 57
    • 20444412608 scopus 로고    scopus 로고
    • Copper-dependent activation of hypoxia-inducible factor (HIF)-1: Implications for ceruloplasmin regulation
    • Martin F, Linden T, Katschinski DM, et al. Copper-dependent activation of hypoxia-inducible factor (HIF)-1: implications for ceruloplasmin regulation. Blood. 2005;105:4613-4619.
    • (2005) Blood , vol.105 , pp. 4613-4619
    • Martin, F.1    Linden, T.2    Katschinski, D.M.3
  • 58
    • 0020000982 scopus 로고
    • Role of prostaglandin EI and copper in angiogenesis
    • Ziehe M, Jones J, Gullino PM. Role of prostaglandin EI and copper in angiogenesis. J Natl Cancer Inst. 1982;69:475-482.
    • (1982) J Natl Cancer Inst , vol.69 , pp. 475-482
    • Ziehe, M.1    Jones, J.2    Gullino, P.M.3
  • 59
    • 18844458093 scopus 로고    scopus 로고
    • Copper lowering therapy with tetrathiomolybdate as an antiangiogenic strategy in cancer
    • Brewer GJ. Copper lowering therapy with tetrathiomolybdate as an antiangiogenic strategy in cancer. Curr Cancer Drug Targets. 2005;5:195-202.
    • (2005) Curr Cancer Drug Targets , vol.5 , pp. 195-202
    • Brewer, G.J.1
  • 60
    • 0141872587 scopus 로고    scopus 로고
    • Dietary glycine inhibits angiogenesis during wound healing and tumor growth
    • Amin K, Li J, Chao WR, Dewhirst MW, Haroon ZA. Dietary glycine inhibits angiogenesis during wound healing and tumor growth. Cancer Biol Ther. 2003;2:173-178.
    • (2003) Cancer Biol Ther , vol.2 , pp. 173-178
    • Amin, K.1    Li, J.2    Chao, W.R.3    Dewhirst, M.W.4    Haroon, Z.A.5
  • 61
    • 0032902830 scopus 로고    scopus 로고
    • Dietary glycine inhibits the growth of B16 melanoma tumors in mice
    • Rose ML, Madren J, Bunzendahl H, Thurman RG. Dietary glycine inhibits the growth of B16 melanoma tumors in mice. Carcinogenesis. 1999;20:793-798.
    • (1999) Carcinogenesis , vol.20 , pp. 793-798
    • Rose, M.L.1    Madren, J.2    Bunzendahl, H.3    Thurman, R.G.4
  • 62
    • 0035731475 scopus 로고    scopus 로고
    • Endothelial cells contain a glycine-gated chloride channel
    • Yamashina S, Konno A, Wheeler MD, et al. Endothelial cells contain a glycine-gated chloride channel. Nutr Cancer. 2001;40:197-204.
    • (2001) Nutr Cancer , vol.40 , pp. 197-204
    • Yamashina, S.1    Konno, A.2    Wheeler, M.D.3
  • 63
    • 0034672477 scopus 로고    scopus 로고
    • NADPH oxidase activity is required for endothelial cell proliferation and migration
    • Abid MR, Kachra Z, Spokes KC, Aird WC. NADPH oxidase activity is required for endothelial cell proliferation and migration. FEBS Lett. 2000;486:252-256.
    • (2000) FEBS Lett , vol.486 , pp. 252-256
    • Abid, M.R.1    Kachra, Z.2    Spokes, K.C.3    Aird, W.C.4
  • 64
    • 0036954803 scopus 로고    scopus 로고
    • Novel role of gp91 (phox)-containing NAD(P)H oxidase in vascular endothelial growth factor-induced signaling and angiogenesis
    • Ushio-Fukai M, Tang Y, Fukai T, et al. Novel role of gp91 (phox)-containing NAD(P)H oxidase in vascular endothelial growth factor-induced signaling and angiogenesis. Circ Res. 2002;91:1160-1167.
    • (2002) Circ Res , vol.91 , pp. 1160-1167
    • Ushio-Fukai, M.1    Tang, Y.2    Fukai, T.3
  • 65
    • 5544237716 scopus 로고    scopus 로고
    • Reactive oxygen species as mediators of angiogenesis signaling: Role of NAD(P)H oxidase
    • Ushio-Fukai M, Alexander RW. Reactive oxygen species as mediators of angiogenesis signaling: role of NAD(P)H oxidase. Mol Cell Biochem. 2004;264:85-97.
    • (2004) Mol Cell Biochem , vol.264 , pp. 85-97
    • Ushio-Fukai, M.1    Alexander, R.W.2
  • 66
    • 15444374584 scopus 로고    scopus 로고
    • Differential oxidation of protein-tyrosine phosphatases
    • Groen A, Lemeer S, van der WT, et al. Differential oxidation of protein-tyrosine phosphatases. J Biol Chem. 2005;280:10298-10304.
    • (2005) J Biol Chem , vol.280 , pp. 10298-10304
    • Groen, A.1    Lemeer, S.2    Van Der, W.T.3
  • 68
    • 0030034098 scopus 로고    scopus 로고
    • Endothelial cell oxidant generation during K(+)-induced membrane depolarization
    • al Mehdi AB, Ischiropoulos H, Fisher AB. Endothelial cell oxidant generation during K(+)-induced membrane depolarization. J Cell Physiol. 1996;166:274-280.
    • (1996) J Cell Physiol , vol.166 , pp. 274-280
    • Al Mehdi, A.B.1    Ischiropoulos, H.2    Fisher, A.B.3
  • 69
    • 0032709605 scopus 로고    scopus 로고
    • Endothelial membrane potential regulates production of both nitric oxide and superoxide: A fundamental determinant of vascular health
    • McCarty MF. Endothelial membrane potential regulates production of both nitric oxide and superoxide: a fundamental determinant of vascular health. Med Hypotheses. 1999;53:277-289.
    • (1999) Med Hypotheses , vol.53 , pp. 277-289
    • McCarty, M.F.1
  • 70
    • 0034705566 scopus 로고    scopus 로고
    • The small G-protein Rac mediates depolarization-induced superoxide formation in human endothelial cells
    • Sohn HY, Keller M, Gloe T, Morawietz H, Rueckschloss U, Pohl U. The small G-protein Rac mediates depolarization-induced superoxide formation in human endothelial cells. J Biol Chem. 2000;275:18745-18750.
    • (2000) J Biol Chem , vol.275 , pp. 18745-18750
    • Sohn, H.Y.1    Keller, M.2    Gloe, T.3    Morawietz, H.4    Rueckschloss, U.5    Pohl, U.6
  • 71
    • 11144265687 scopus 로고    scopus 로고
    • Membrane depolarization and NADPH oxidase activation in aortic endothelium during ischemia reflect altered mechanotransduction
    • Matsuzaki I, Chatterjee S, Debolt K, Manevich Y, Zhang Q, Fisher AB. Membrane depolarization and NADPH oxidase activation in aortic endothelium during ischemia reflect altered mechanotransduction. Am J Physiol Heart Circ Physiol. 2005;288:H336-H343.
    • (2005) Am J Physiol Heart Circ Physiol , vol.288
    • Matsuzaki, I.1    Chatterjee, S.2    Debolt, K.3    Manevich, Y.4    Zhang, Q.5    Fisher, A.B.6
  • 72
    • 28144438500 scopus 로고    scopus 로고
    • The anti-angiogenic impact of dietary glycine may be mediated by a hyperpolarization-induced suppression of NADPH oxidase activity
    • In press
    • McCarty MF. The anti-angiogenic impact of dietary glycine may be mediated by a hyperpolarization-induced suppression of NADPH oxidase activity. Med Hypotheses. 2005. In press.
    • (2005) Med Hypotheses
    • McCarty, M.F.1
  • 73
    • 0042379916 scopus 로고    scopus 로고
    • The vascular NAD(P)H oxidases as therapeutic targets in cardiovascular diseases
    • Cai H, Griendling KK, Harrison DG. The vascular NAD(P)H oxidases as therapeutic targets in cardiovascular diseases. Trends Pharmacol Sci. 2003;24:471-478.
    • (2003) Trends Pharmacol Sci , vol.24 , pp. 471-478
    • Cai, H.1    Griendling, K.K.2    Harrison, D.G.3
  • 74
    • 0032760588 scopus 로고    scopus 로고
    • Selenium-induced inhibition of angiogenesis in mammary cancer at chemopreventive levels of intake
    • Jiang C, Jiang W, Ip C, Ganther H, Lu J. Selenium-induced inhibition of angiogenesis in mammary cancer at chemopreventive levels of intake. Mol Carcinog. 1999;26:213-225.
    • (1999) Mol Carcinog , vol.26 , pp. 213-225
    • Jiang, C.1    Jiang, W.2    Ip, C.3    Ganther, H.4    Lu, J.5
  • 75
    • 12744261583 scopus 로고    scopus 로고
    • Thioredoxin reductase regulates angiogenesis by increasing endothelial cell-derived vascular endothelial growth factor
    • Streicher KL, Sylte MJ, Johnson SE, Sordillo LM. Thioredoxin reductase regulates angiogenesis by increasing endothelial cell-derived vascular endothelial growth factor. Nutr Cancer. 2004;50:221-231.
    • (2004) Nutr Cancer , vol.50 , pp. 221-231
    • Streicher, K.L.1    Sylte, M.J.2    Johnson, S.E.3    Sordillo, L.M.4
  • 76
    • 0032848137 scopus 로고    scopus 로고
    • Selenium metabolism, selenoproteins and mechanisms of cancer prevention: Complexities with thioredoxin reductase
    • Ganther HE. Selenium metabolism, selenoproteins and mechanisms of cancer prevention: complexities with thioredoxin reductase. Carcinogenesis. 1999;20:1657-1666.
    • (1999) Carcinogenesis , vol.20 , pp. 1657-1666
    • Ganther, H.E.1
  • 77
    • 0034110596 scopus 로고    scopus 로고
    • Thioredoxin inhibits tumor necrosis factor- Or interleukin-1-induced NF-kappaB activation at a level upstream of NF-kappaB-inducing kinase
    • Takeuchi J, Hirota K, Itoh T, et al. Thioredoxin inhibits tumor necrosis factor- or interleukin-1-induced NF-kappaB activation at a level upstream of NF-kappaB-inducing kinase. Antioxid Redox Signal. 2000;2:83-92.
    • (2000) Antioxid Redox Signal , vol.2 , pp. 83-92
    • Takeuchi, J.1    Hirota, K.2    Itoh, T.3
  • 78
    • 1642474377 scopus 로고    scopus 로고
    • Overexpression of thioredoxin reductase 1 regulates NF-kappa B activation
    • Sakurai A, Yuasa K, Shoji Y, et al. Overexpression of thioredoxin reductase 1 regulates NF-kappa B activation. J Cell Physiol. 2004;198:22-30.
    • (2004) J Cell Physiol , vol.198 , pp. 22-30
    • Sakurai, A.1    Yuasa, K.2    Shoji, Y.3
  • 79
    • 0035679739 scopus 로고    scopus 로고
    • Antiangiogenic activity of selenium in cancer chemoprevention: Metabolite-specific effects
    • Lu J, Jiang C. Antiangiogenic activity of selenium in cancer chemoprevention: metabolite-specific effects. Nutr Cancer. 2001;40:64-73.
    • (2001) Nutr Cancer , vol.40 , pp. 64-73
    • Lu, J.1    Jiang, C.2
  • 80
    • 8444230796 scopus 로고    scopus 로고
    • Methyl selenium-induced vascular endothelial apoptosis is executed by caspases and principally mediated by p38 MAPK pathway
    • Jiang C, Kim KH, Wang Z, Lu J. Methyl selenium-induced vascular endothelial apoptosis is executed by caspases and principally mediated by p38 MAPK pathway. Nutr Cancer. 2004;49:174-183.
    • (2004) Nutr Cancer , vol.49 , pp. 174-183
    • Jiang, C.1    Kim, K.H.2    Wang, Z.3    Lu, J.4
  • 81
    • 0345868261 scopus 로고    scopus 로고
    • Inorganic selenium retards progression of experimental hormone refractory prostate cancer
    • Corcoran NM, Najdovska M, Costello AJ. Inorganic selenium retards progression of experimental hormone refractory prostate cancer. J Urol. 2004;171:907-910.
    • (2004) J Urol , vol.171 , pp. 907-910
    • Corcoran, N.M.1    Najdovska, M.2    Costello, A.J.3
  • 84
    • 0033991061 scopus 로고    scopus 로고
    • Regulation of vascular endothelial growth factor expression by insulin-like growth factor-I in endometrial adenocarcinoma cells
    • Bermont L, Lamielle F, Fauconnet S, Esumi H, Weisz A, Adessi GL. Regulation of vascular endothelial growth factor expression by insulin-like growth factor-I in endometrial adenocarcinoma cells. Int J Cancer. 2000;85:117-123.
    • (2000) Int J Cancer , vol.85 , pp. 117-123
    • Bermont, L.1    Lamielle, F.2    Fauconnet, S.3    Esumi, H.4    Weisz, A.5    Adessi, G.L.6
  • 85
    • 0033873768 scopus 로고    scopus 로고
    • Insulin-like growth factor I stimulates angiogenesis and the production of vascular endothelial growth factor
    • Dunn SE. Insulin-like growth factor I stimulates angiogenesis and the production of vascular endothelial growth factor. Growth Horm IGF Res. 2000;10(suppl A):S41-S42.
    • (2000) Growth Horm IGF Res , vol.10 , Issue.SUPPL. A
    • Dunn, S.E.1
  • 86
    • 0036797073 scopus 로고    scopus 로고
    • Impact of insulin-like growth factor receptor-I function on angiogenesis, growth, and metastasis of colon cancer
    • Reinmuth N, Fan F, Liu W, et al. Impact of insulin-like growth factor receptor-I function on angiogenesis, growth, and metastasis of colon cancer. Lab Invest. 2002;82:1377-1389.
    • (2002) Lab Invest , vol.82 , pp. 1377-1389
    • Reinmuth, N.1    Fan, F.2    Liu, W.3
  • 87
    • 0037470435 scopus 로고    scopus 로고
    • Requirement of different signaling pathways mediated by insulin-like growth factor-I receptor for proliferation, invasion, and VPF/VEGF expression in a pancreatic carcinoma cell line
    • Zeng H, Datta K, Neid M, Li J, Parangi S, Mukhopadhyay D. Requirement of different signaling pathways mediated by insulin-like growth factor-I receptor for proliferation, invasion, and VPF/VEGF expression in a pancreatic carcinoma cell line. Biochem Biophys Res Commun. 2003;302:46-55.
    • (2003) Biochem Biophys Res Commun , vol.302 , pp. 46-55
    • Zeng, H.1    Datta, K.2    Neid, M.3    Li, J.4    Parangi, S.5    Mukhopadhyay, D.6
  • 88
    • 0842281886 scopus 로고    scopus 로고
    • Role of IGF-1R in mediating breast cancer invasion and metastasis
    • Kucab JE, Dunn SE. Role of IGF-1R in mediating breast cancer invasion and metastasis. Breast Dis. 2003;17:41-47.
    • (2003) Breast Dis , vol.17 , pp. 41-47
    • Kucab, J.E.1    Dunn, S.E.2
  • 89
    • 0032758384 scopus 로고    scopus 로고
    • Regulation of vascular endothelial growth factor-dependent retinal neovascularization by insulin-like growth factor-1 receptor
    • Smith LE, Shen W, Perruzzi C, et al. Regulation of vascular endothelial growth factor-dependent retinal neovascularization by insulin-like growth factor-1 receptor. Nat Med. 1999;5:1390-1395.
    • (1999) Nat Med , vol.5 , pp. 1390-1395
    • Smith, L.E.1    Shen, W.2    Perruzzi, C.3
  • 90
    • 0036973848 scopus 로고    scopus 로고
    • Effect of diet and exercise on serum insulin, IGF-I, and IGFBP-1 levels and growth of LNCaP cells in vitro (United States)
    • Ngo TH, Barnard RJ, Tymchuk CN, Cohen P, Aronson WJ. Effect of diet and exercise on serum insulin, IGF-I, and IGFBP-1 levels and growth of LNCaP cells in vitro (United States). Cancer Causes Control. 2002;13:929-935.
    • (2002) Cancer Causes Control , vol.13 , pp. 929-935
    • Ngo, T.H.1    Barnard, R.J.2    Tymchuk, C.N.3    Cohen, P.4    Aronson, W.J.5
  • 91
    • 0038577113 scopus 로고    scopus 로고
    • Insulin-like growth factor I (IGF-I) and IGF binding protein-1 modulate prostate cancer cell growth and apoptosis: Possible mediators for the effects of diet and exercise on cancer cell survival
    • Ngo TH, Barnard RJ, Leung PS, Cohen P, Aronson WJ. Insulin-like growth factor I (IGF-I) and IGF binding protein-1 modulate prostate cancer cell growth and apoptosis: possible mediators for the effects of diet and exercise on cancer cell survival. Endocrinology. 2003;144:2319-2324.
    • (2003) Endocrinology , vol.144 , pp. 2319-2324
    • Ngo, T.H.1    Barnard, R.J.2    Leung, P.S.3    Cohen, P.4    Aronson, W.J.5
  • 92
    • 0043172559 scopus 로고    scopus 로고
    • A low-fat diet and/or strenuous exercise alters the IGF axis in vivo and reduces prostate tumor cell growth in vitro
    • Barnard RJ, Ngo TH, Leung PS, Aronson WJ, Golding LA. A low-fat diet and/or strenuous exercise alters the IGF axis in vivo and reduces prostate tumor cell growth in vitro. Prostate. 2003;56:201-206.
    • (2003) Prostate , vol.56 , pp. 201-206
    • Barnard, R.J.1    Ngo, T.H.2    Leung, P.S.3    Aronson, W.J.4    Golding, L.A.5
  • 93
    • 22544435988 scopus 로고    scopus 로고
    • Prevention of cancer through lifestyle changes
    • Barnard RJ. Prevention of cancer through lifestyle changes. Evid Based Complement Alternat. Med. 2004;1:233-239.
    • (2004) Evid Based Complement Alternat Med , vol.1 , pp. 233-239
    • Barnard, R.J.1
  • 94
    • 23744506376 scopus 로고    scopus 로고
    • Intensive lifestyle changes may affect the progression of prostate cancer
    • Ornish D, Weidner G, Fair WR, et al. Intensive lifestyle changes may affect the progression of prostate cancer. J Urol. 2005;174:1065-1069.
    • (2005) J Urol , vol.174 , pp. 1065-1069
    • Ornish, D.1    Weidner, G.2    Fair, W.R.3
  • 95
    • 16544366164 scopus 로고    scopus 로고
    • Nutrition, insulin, 1GF-1 metabolism and cancer risk: A summary of epidemiological evidence
    • Kaaks R. Nutrition, insulin, 1GF-1 metabolism and cancer risk: a summary of epidemiological evidence. Novartis Found Symp. 2004;262:247-260.
    • (2004) Novartis Found Symp , vol.262 , pp. 247-260
    • Kaaks, R.1
  • 96
    • 4644250349 scopus 로고    scopus 로고
    • Insulin and IGF-I as determinants of low "Western" cancer rates in the rural third world
    • McCarty MF. Insulin and IGF-I as determinants of low "Western" cancer rates in the rural third world. Int J Epidemiol. 2004;33:908-910.
    • (2004) Int J Epidemiol , vol.33 , pp. 908-910
    • McCarty, M.F.1
  • 97
    • 0030724178 scopus 로고    scopus 로고
    • Fatty acid regulation of breast cancer cell growth and invasion
    • Rose DP, Connolly JM, Liu XH. Fatty acid regulation of breast cancer cell growth and invasion. Adv Exp Med Biol. 1997;422:47-55.
    • (1997) Adv Exp Med Biol , vol.422 , pp. 47-55
    • Rose, D.P.1    Connolly, J.M.2    Liu, X.H.3
  • 98
    • 0031457713 scopus 로고    scopus 로고
    • Omega-3 polyunsaturated fatty acids in rodent models of breast cancer
    • Cave WT, Jr. Omega-3 polyunsaturated fatty acids in rodent models of breast cancer. Breast Cancer Res Treat. 1997;46:239-246.
    • (1997) Breast Cancer Res Treat , vol.46 , pp. 239-246
    • Cave Jr., W.T.1
  • 99
    • 0033637473 scopus 로고    scopus 로고
    • Regulation of tumor angiogenesis by dietary fatty acids and eicosanoids
    • Rose DP, Connolly JM. Regulation of tumor angiogenesis by dietary fatty acids and eicosanoids. Nutr Cancer. 2000;37:119-127.
    • (2000) Nutr Cancer , vol.37 , pp. 119-127
    • Rose, D.P.1    Connolly, J.M.2
  • 100
    • 9744228743 scopus 로고    scopus 로고
    • (n-3) fatty acids and cancer therapy
    • Hardman WE. (n-3) fatty acids and cancer therapy. J Nutr. 2004;134:3427S-3430S.
    • (2004) J Nutr , vol.134
    • Hardman, W.E.1
  • 101
    • 0141990970 scopus 로고    scopus 로고
    • N-3 polyunsaturated fatty acids decrease mucosal/epidermal reactions and enhance antitumour effect of ionising radiation with inhibition of tumour angiogenesis
    • Wen B, Deutsch E, Opolon P, et al. N-3 polyunsaturated fatty acids decrease mucosal/epidermal reactions and enhance antitumour effect of ionising radiation with inhibition of tumour angiogenesis. Br J Cancer. 2003;89:1102-1107.
    • (2003) Br J Cancer , vol.89 , pp. 1102-1107
    • Wen, B.1    Deutsch, E.2    Opolon, P.3
  • 102
    • 26844490545 scopus 로고    scopus 로고
    • Dietary omega-3 fatty acids and ionizing irradiation on human breast cancer xenograft growth and angiogenesis
    • Hardman WE, Sun L, Short N, Cameron IL. Dietary omega-3 fatty acids and ionizing irradiation on human breast cancer xenograft growth and angiogenesis. Cancer Cell Int. 2005;5:12.
    • (2005) Cancer Cell Int , vol.5 , pp. 12
    • Hardman, W.E.1    Sun, L.2    Short, N.3    Cameron, I.L.4
  • 103
    • 0031824862 scopus 로고    scopus 로고
    • Eicosapentaenoic acid attenuates vascular endothelial growth factor-induced proliferation via inhibiting Flk-1 receptor expression in bovine carotid artery endothelial cells
    • Yang SP, Morita I, Murota SI. Eicosapentaenoic acid attenuates vascular endothelial growth factor-induced proliferation via inhibiting Flk-1 receptor expression in bovine carotid artery endothelial cells. J Cell Physiol. 1998;176:342-349.
    • (1998) J Cell Physiol , vol.176 , pp. 342-349
    • Yang, S.P.1    Morita, I.2    Murota, S.I.3
  • 104
    • 0034122538 scopus 로고    scopus 로고
    • Regulation of angiogenesis by controlling VEGF receptor
    • Murota SI, Onodera M, Morita I. Regulation of angiogenesis by controlling VEGF receptor. Ann N Y Acad Sci. 2000;902:208-212.
    • (2000) Ann N Y Acad Sci , vol.902 , pp. 208-212
    • Murota, S.I.1    Onodera, M.2    Morita, I.3
  • 105
    • 0037733126 scopus 로고    scopus 로고
    • Docosapentaenoic acid (22:5, n-3) suppressed tube-forming activity in endothelial cells induced by vascular endothelial growth factor
    • Tsuji M, Murota SI, Morita I. Docosapentaenoic acid (22:5, n-3) suppressed tube-forming activity in endothelial cells induced by vascular endothelial growth factor. Prostaglandins Leukot Essent Fatty Acids. 2003;68:337-342.
    • (2003) Prostaglandins Leukot Essent Fatty Acids , vol.68 , pp. 337-342
    • Tsuji, M.1    Murota, S.I.2    Morita, I.3
  • 106
    • 0029936742 scopus 로고    scopus 로고
    • The effect of polyunsaturated fatty acids on the progress of cachexia in patients with pancreatic cancer
    • Wigmore SJ, Ross JA, Falconer JS, et al. The effect of polyunsaturated fatty acids on the progress of cachexia in patients with pancreatic cancer. Nutrition. 1996;12:S27-S30.
    • (1996) Nutrition , vol.12
    • Wigmore, S.J.1    Ross, J.A.2    Falconer, J.S.3
  • 107
    • 1942424855 scopus 로고    scopus 로고
    • Reduced total energy expenditure and physical activity in cachectic patients with pancreatic cancer can be modulated by an energy and protein dense oral supplement enriched with n-3 fatty acids
    • Moses AW, Slater C, Preston T, Barber MD, Fearon KC. Reduced total energy expenditure and physical activity in cachectic patients with pancreatic cancer can be modulated by an energy and protein dense oral supplement enriched with n-3 fatty acids. Br J Cancer. 2004;90:996-1002.
    • (2004) Br J Cancer , vol.90 , pp. 996-1002
    • Moses, A.W.1    Slater, C.2    Preston, T.3    Barber, M.D.4    Fearon, K.C.5
  • 108
    • 2942706075 scopus 로고    scopus 로고
    • An eicosapentaenoic acid supplement versus megestrol acetate versus both for patients with cancer-associated wasting: A North Central Cancer Treatment Group and National Cancer Institute of Canada collaborative effort
    • Jatoi A, Rowland K, Loprinzi CL, et al. An eicosapentaenoic acid supplement versus megestrol acetate versus both for patients with cancer-associated wasting: a North Central Cancer Treatment Group and National Cancer Institute of Canada collaborative effort. J Clin Oncol. 2004;22:2469-2476.
    • (2004) J Clin Oncol , vol.22 , pp. 2469-2476
    • Jatoi, A.1    Rowland, K.2    Loprinzi, C.L.3
  • 110
    • 9244221653 scopus 로고    scopus 로고
    • Targeting multiple signaling pathways as a strategy for managing prostate cancer: Multifocal signal modulation therapy
    • McCarty MF. Targeting multiple signaling pathways as a strategy for managing prostate cancer: multifocal signal modulation therapy. Integr Cancer Ther. 2004;3:349-380.
    • (2004) Integr Cancer Ther , vol.3 , pp. 349-380
    • McCarty, M.F.1
  • 111
    • 0037386939 scopus 로고    scopus 로고
    • Combination of a selective cyclooxygenase-2 inhibitor with epidermal growth factor receptor tyrosine kinase inhibitor ZD1839 and protein kinase a antisense causes cooperative antitumor and antiangiogenic effect
    • Tortora G, Caputo R, Damiano V, et al. Combination of a selective cyclooxygenase-2 inhibitor with epidermal growth factor receptor tyrosine kinase inhibitor ZD1839 and protein kinase A antisense causes cooperative antitumor and antiangiogenic effect. Clin Cancer Res. 2003;9:1566-1572.
    • (2003) Clin Cancer Res , vol.9 , pp. 1566-1572
    • Tortora, G.1    Caputo, R.2    Damiano, V.3
  • 112
    • 11244335640 scopus 로고    scopus 로고
    • Strategies for multiple signalling inhibition
    • Tortora G, Bianco R, Daniele G. Strategies for multiple signalling inhibition. J Chemother. 2004;16(suppl 4):41-43.
    • (2004) J Chemother , vol.16 , Issue.4 SUPPL. , pp. 41-43
    • Tortora, G.1    Bianco, R.2    Daniele, G.3
  • 113
    • 1842419766 scopus 로고    scopus 로고
    • Therapeutic integration of signal transduction targeting agents and conventional anti-cancer treatments
    • Melisi D, Troiani T, Damiano V, Tortora G, Ciardiello F. Therapeutic integration of signal transduction targeting agents and conventional anti-cancer treatments. Endocr Relat Cancer. 2004;11:51-68.
    • (2004) Endocr Relat Cancer , vol.11 , pp. 51-68
    • Melisi, D.1    Troiani, T.2    Damiano, V.3    Tortora, G.4    Ciardiello, F.5
  • 114
    • 28144440628 scopus 로고    scopus 로고
    • Pre-administration of high-dose aspirin or salicylate, suppressors of NF-kappaB activation, may increase the chemosensitivity of many cancers
    • In press
    • McCarty MF. Pre-administration of high-dose aspirin or salicylate, suppressors of NF-kappaB activation, may increase the chemosensitivity of many cancers. Med Hypotheses. 2005. In press.
    • (2005) Med Hypotheses
    • McCarty, M.F.1
  • 115
    • 0035831465 scopus 로고    scopus 로고
    • Vascular endothelial growth factor expression of intercellular adhesion molecule 1 (ICAM-1), vascular cell adhesion molecule 1 (VCAM-1), and E-selectin through nuclear factor-kappa B activation in endothelial cells
    • Kim I, Moon SO, Kim SH, Kim HJ, Koh YS, Koh GY. Vascular endothelial growth factor expression of intercellular adhesion molecule 1 (ICAM-1), vascular cell adhesion molecule 1 (VCAM-1), and E-selectin through nuclear factor-kappa B activation in endothelial cells. J Biol Chem. 2001;276:7614-7620.
    • (2001) J Biol Chem , vol.276 , pp. 7614-7620
    • Kim, I.1    Moon, S.O.2    Kim, S.H.3    Kim, H.J.4    Koh, Y.S.5    Koh, G.Y.6
  • 116
    • 0035437862 scopus 로고    scopus 로고
    • NF-kappaB mediates FGF signal regulation of msx-1 expression
    • Bushdid PB, Chen CL, Brantley DM, et al. NF-kappaB mediates FGF signal regulation of msx-1 expression. Dev Biol. 2001;237:107-115.
    • (2001) Dev Biol , vol.237 , pp. 107-115
    • Bushdid, P.B.1    Chen, C.L.2    Brantley, D.M.3
  • 117
    • 0037085569 scopus 로고    scopus 로고
    • Nuclear factor kappaB dependency of platelet-activating factor-induced angiogenesis
    • Ko HM, Seo KH, Han SJ, et al. Nuclear factor kappaB dependency of platelet-activating factor-induced angiogenesis. Cancer Res. 2002;62:1809-1814.
    • (2002) Cancer Res , vol.62 , pp. 1809-1814
    • Ko, H.M.1    Seo, K.H.2    Han, S.J.3
  • 119
    • 0036315845 scopus 로고    scopus 로고
    • Alpha 5 beta 1 integrin activates an NF-kappa B-dependent program of gene expression important for angiogenesis and inflammation
    • Klein S, de Fougerolles AR, Blaikie P, et al. Alpha 5 beta 1 integrin activates an NF-kappa B-dependent program of gene expression important for angiogenesis and inflammation. Mol Cell Biol. 2002;22:5912-5922.
    • (2002) Mol Cell Biol , vol.22 , pp. 5912-5922
    • Klein, S.1    De Fougerolles, A.R.2    Blaikie, P.3
  • 120
    • 0030014964 scopus 로고    scopus 로고
    • Involvement of the transcription factor NF-kappaB in tubular morphogenesis of human microvascular endothelial cells by oxidative stress
    • Shono T, Ono M, Izumi H, et al. Involvement of the transcription factor NF-kappaB in tubular morphogenesis of human microvascular endothelial cells by oxidative stress. Mol Cell Biol. 1996;16:4231-4239.
    • (1996) Mol Cell Biol , vol.16 , pp. 4231-4239
    • Shono, T.1    Ono, M.2    Izumi, H.3
  • 121
    • 2342488884 scopus 로고    scopus 로고
    • Tubular morphogenesis by genotoxic therapeutic agents that induce NF-kappaB activation in human vascular endothelial cells
    • Goto D, Izumi H, Ono M, Okamoto T, Kohno K, Kuwano M. Tubular morphogenesis by genotoxic therapeutic agents that induce NF-kappaB activation in human vascular endothelial cells. Angiogenesis. 1998;2:345-356.
    • (1998) Angiogenesis , vol.2 , pp. 345-356
    • Goto, D.1    Izumi, H.2    Ono, M.3    Okamoto, T.4    Kohno, K.5    Kuwano, M.6
  • 122
    • 0033020061 scopus 로고    scopus 로고
    • Suppression of retinal neovascularization by the NF-kappaB inhibitor pyrrolidine dithiocarbamate in mice
    • Yoshida A, Yoshida S, Ishibashi T, Kuwano M, Inomata H. Suppression of retinal neovascularization by the NF-kappaB inhibitor pyrrolidine dithiocarbamate in mice. Invest Ophthalmol Vis Sci. 1999;40:1624-1629.
    • (1999) Invest Ophthalmol Vis Sci , vol.40 , pp. 1624-1629
    • Yoshida, A.1    Yoshida, S.2    Ishibashi, T.3    Kuwano, M.4    Inomata, H.5
  • 123
    • 0033020061 scopus 로고    scopus 로고
    • Suppression of retinal neovascularization by the NF-kappaB inhibitor pyrrolidine dithiocarbamate in mice
    • Yoshida A, Yoshida S, Ishibashi T, Kuwano M, Inomata H. Suppression of retinal neovascularization by the NF-kappaB inhibitor pyrrolidine dithiocarbamate in mice. Invest Ophthalmol Vis Sci. 1999;40:1624-1629.
    • (1999) Invest Ophthalmol Vis Sci , vol.40 , pp. 1624-1629
    • Yoshida, A.1    Yoshida, S.2    Ishibashi, T.3    Kuwano, M.4    Inomata, H.5
  • 124
    • 0035869252 scopus 로고    scopus 로고
    • Adenovirus-mediated expression of a mutant IkappaB kinase 2 inhibits the response of endothelial cells to inflammatory stimuli
    • Oitzinger W, Hofer-Warbinek R, Schmid JA, Koshelnick Y, Binder BR, De Martin R. Adenovirus-mediated expression of a mutant IkappaB kinase 2 inhibits the response of endothelial cells to inflammatory stimuli. Blood. 2001;97:1611-1617.
    • (2001) Blood , vol.97 , pp. 1611-1617
    • Oitzinger, W.1    Hofer-Warbinek, R.2    Schmid, J.A.3    Koshelnick, Y.4    Binder, B.R.5    De Martin, R.6
  • 125
    • 0036007964 scopus 로고    scopus 로고
    • The alpha(v)beta3 integrin, NF-kappaB, osteoprotegerin endothelial cell survival pathway: Potential role in angiogenesis
    • Scatena M, Giachelli C. The alpha(v)beta3 integrin, NF-kappaB, osteoprotegerin endothelial cell survival pathway: potential role in angiogenesis. Trends Cardiovasc Med. 2002;12:83-88.
    • (2002) Trends Cardiovasc Med , vol.12 , pp. 83-88
    • Scatena, M.1    Giachelli, C.2
  • 126
    • 13944268747 scopus 로고    scopus 로고
    • The homeoboxgene Gax inhibits angiogenesis through inhibition of nuclear factor-kappaB-dependent endothelial cell gene expression
    • Patel S, Leal AD, Gorski DH. The homeoboxgene Gax inhibits angiogenesis through inhibition of nuclear factor-kappaB-dependent endothelial cell gene expression. Cancer Res. 2005;65:1414-1424.
    • (2005) Cancer Res , vol.65 , pp. 1414-1424
    • Patel, S.1    Leal, A.D.2    Gorski, D.H.3
  • 127
    • 0032487857 scopus 로고    scopus 로고
    • The anti-inflammatory agents aspirin and salicylate inhibit the activity of I(kappa)B kinase-beta
    • Yin MJ, Yamamoto Y, Gaynor RB. The anti-inflammatory agents aspirin and salicylate inhibit the activity of I(kappa)B kinase-beta. Nature. 1998;396:77-80.
    • (1998) Nature , vol.396 , pp. 77-80
    • Yin, M.J.1    Yamamoto, Y.2    Gaynor, R.B.3
  • 128
    • 0033578879 scopus 로고    scopus 로고
    • Sulindac inhibits activation of the NF-kappaB pathway
    • Yamamoto Y, Yin MJ, Lin KM, Gaynor RB. Sulindac inhibits activation of the NF-kappaB pathway. J Biol Chem. 1999;274:27307-27314.
    • (1999) J Biol Chem , vol.274 , pp. 27307-27314
    • Yamamoto, Y.1    Yin, M.J.2    Lin, K.M.3    Gaynor, R.B.4
  • 129
    • 20344402336 scopus 로고    scopus 로고
    • Salicylate inhibition of rat mammary carcinogenesis and angiogenesis in female rat compatible with misoprostol administration
    • Ghezzo F, Cesano L, Mognetti B, et al. Salicylate inhibition of rat mammary carcinogenesis and angiogenesis in female rat compatible with misoprostol administration. Int J Oncol. 2005;26:697-702.
    • (2005) Int J Oncol , vol.26 , pp. 697-702
    • Ghezzo, F.1    Cesano, L.2    Mognetti, B.3
  • 130
    • 3042748129 scopus 로고    scopus 로고
    • Multiple roles of COX-2 in tumor angiogenesis: A target for antiangiogenic therapy
    • Gately S, Li WW. Multiple roles of COX-2 in tumor angiogenesis: a target for antiangiogenic therapy. Semin Oncol. 2004;31:2-11.
    • (2004) Semin Oncol , vol.31 , pp. 2-11
    • Gately, S.1    Li, W.W.2
  • 133
    • 0142215651 scopus 로고    scopus 로고
    • Sodium butyrate inhibits angiogenesis of human intestinal microvascular endothelial cells through COX-2 inhibition
    • Ogawa H, Rafiee P, Fisher PJ, Johnson NA, Otterson MF, Binion DG. Sodium butyrate inhibits angiogenesis of human intestinal microvascular endothelial cells through COX-2 inhibition. FEBS Lett. 2003;554:88-94.
    • (2003) FEBS Lett , vol.554 , pp. 88-94
    • Ogawa, H.1    Rafiee, P.2    Fisher, P.J.3    Johnson, N.A.4    Otterson, M.F.5    Binion, D.G.6
  • 134
    • 0034791297 scopus 로고    scopus 로고
    • NSAIDs inhibit alpha V beta 3 integrin-mediated and Cdc42/Rac-dependent endothelial-cell spreading, migration and angiogenesis
    • Dormond O, Foletti A, Paroz C, Ruegg C. NSAIDs inhibit alpha V beta 3 integrin-mediated and Cdc42/Rac-dependent endothelial-cell spreading, migration and angiogenesis. Nat Med. 2001;7:1041-1047.
    • (2001) Nat Med , vol.7 , pp. 1041-1047
    • Dormond, O.1    Foletti, A.2    Paroz, C.3    Ruegg, C.4
  • 135
    • 0141679091 scopus 로고    scopus 로고
    • Angiogenic effects of prostaglandin E2 are mediated by up-regulation of CXCR4 on human microvascular endothelial cells
    • Salcedo R, Zhang X, Young HA, et al. Angiogenic effects of prostaglandin E2 are mediated by up-regulation of CXCR4 on human microvascular endothelial cells. Blood. 2003;102:1966-1977.
    • (2003) Blood , vol.102 , pp. 1966-1977
    • Salcedo, R.1    Zhang, X.2    Young, H.A.3
  • 136
    • 0029149240 scopus 로고
    • Misoprostol dosage in the prevention of nonsteroidal anti-inflammatory drug-induced gastric and duodenal ulcers: A comparison of three regimens
    • Raskin JB, White RH, Jackson JE, et al. Misoprostol dosage in the prevention of nonsteroidal anti-inflammatory drug-induced gastric and duodenal ulcers: a comparison of three regimens. Ann Intern Med. 1995;123:344-350.
    • (1995) Ann Intern Med , vol.123 , pp. 344-350
    • Raskin, J.B.1    White, R.H.2    Jackson, J.E.3
  • 137
    • 0034693877 scopus 로고    scopus 로고
    • Role of Src expression and activation in human cancer
    • Irby RB, Yeatman TJ. Role of Src expression and activation in human cancer. Oncogene. 2000;19:5636-5642.
    • (2000) Oncogene , vol.19 , pp. 5636-5642
    • Irby, R.B.1    Yeatman, T.J.2
  • 138
    • 0037150728 scopus 로고    scopus 로고
    • Src in cancer: Deregulation and consequences for cell behaviour
    • Frame MC. Src in cancer: deregulation and consequences for cell behaviour. Biochim Biophys Acta. 2002;1602:114-130.
    • (2002) Biochim Biophys Acta , vol.1602 , pp. 114-130
    • Frame, M.C.1
  • 139
    • 0034193789 scopus 로고    scopus 로고
    • Substituted 5,7-diphenyl-pyrrolo[2,3d]pyrimidines: Potent inhibitors of the tyrosine kinase c-Src
    • Missbach M, Altmann E, Widler L, et al. Substituted 5,7-diphenyl- pyrrolo[2,3d]pyrimidines: potent inhibitors of the tyrosine kinase c-Src. Bioorg Med Chem Lett. 2000;10:945-949.
    • (2000) Bioorg Med Chem Lett , vol.10 , pp. 945-949
    • Missbach, M.1    Altmann, E.2    Widler, L.3
  • 140
    • 0142058167 scopus 로고    scopus 로고
    • Pyrrolopyrimidine c-Src inhibitors reduce growth, adhesion, motility and invasion of prostate cancer cells in vitro
    • Recchia I, Rucci N, Festuccia C, et al. Pyrrolopyrimidine c-Src inhibitors reduce growth, adhesion, motility and invasion of prostate cancer cells in vitro. Eur J Cancer. 2003;39:1927-1935.
    • (2003) Eur J Cancer , vol.39 , pp. 1927-1935
    • Recchia, I.1    Rucci, N.2    Festuccia, C.3
  • 141
    • 0032541571 scopus 로고    scopus 로고
    • The many faces of Src: Multiple functions of a prototypical tyrosine kinase
    • Schwartzberg PL. The many faces of Src: multiple functions of a prototypical tyrosine kinase. Oncogene. 1998;17:1463-1468.
    • (1998) Oncogene , vol.17 , pp. 1463-1468
    • Schwartzberg, P.L.1
  • 142
    • 34248397608 scopus 로고    scopus 로고
    • Src kinase becomes preferentially associated with the VEGFR, KDR/Flk-1, following VEGF stimulation of vascular endothelial cells
    • Chou MT, Wang J, Fujita DJ, Src kinase becomes preferentially associated with the VEGFR, KDR/Flk-1, following VEGF stimulation of vascular endothelial cells. BMC Biochem. 2002;3:32.
    • (2002) BMC Biochem , vol.3 , pp. 32
    • Chou, M.T.1    Wang, J.2    Fujita, D.J.3
  • 143
    • 0242333907 scopus 로고    scopus 로고
    • Inactivation of Src family kinases inhibits angiogenesis in vivo: Implications for a mechanism involving organization of the actin cytoskeleton
    • Kilarski WW, Jura N, Gerwins P. Inactivation of Src family kinases inhibits angiogenesis in vivo: implications for a mechanism involving organization of the actin cytoskeleton. Exp Cell Res. 2003;291:70-82.
    • (2003) Exp Cell Res , vol.291 , pp. 70-82
    • Kilarski, W.W.1    Jura, N.2    Gerwins, P.3
  • 144
    • 21744435561 scopus 로고    scopus 로고
    • A novel Src kinase inhibitor, M475271, inhibits VEGF-induced human umbilical vein endothelial cell proliferation and migration
    • Ali N, Yoshizumi M, Fujita Y, et al. A novel Src kinase inhibitor, M475271, inhibits VEGF-induced human umbilical vein endothelial cell proliferation and migration. J Pharmacol Sci. 2005;98:130-141.
    • (2005) J Pharmacol Sci , vol.98 , pp. 130-141
    • Ali, N.1    Yoshizumi, M.2    Fujita, Y.3
  • 145
    • 1642462125 scopus 로고    scopus 로고
    • Herbimycin a inhibits angiogenic activity in endothelial cells and reduces neovascularization in a rat model of retinopathy of prematurity
    • McCollum GW, Rajaratnam VS, Bullard LE, Yang R, Penn JS. Herbimycin A inhibits angiogenic activity in endothelial cells and reduces neovascularization in a rat model of retinopathy of prematurity. Exp Eye Res. 2004;78:987-995.
    • (2004) Exp Eye Res , vol.78 , pp. 987-995
    • McCollum, G.W.1    Rajaratnam, V.S.2    Bullard, L.E.3    Yang, R.4    Penn, J.S.5
  • 146
    • 0034968914 scopus 로고    scopus 로고
    • Pp60(c-src) modulates microvascular endothelial phenotype and in vitro angiogenesis
    • Marx M, Warren SL, Madri JA. pp60(c-src) modulates microvascular endothelial phenotype and in vitro angiogenesis. Exp Mol Pathol. 2001;70:201-213.
    • (2001) Exp Mol Pathol , vol.70 , pp. 201-213
    • Marx, M.1    Warren, S.L.2    Madri, J.A.3
  • 147
    • 0034424220 scopus 로고    scopus 로고
    • Src inhibitors: Drugs for the treatment of osteoporosis, cancer or both?
    • Susva M, Missbach M, Green J. Src inhibitors: drugs for the treatment of osteoporosis, cancer or both? Trends Pharmacol Sci. 2000;21:489-495.
    • (2000) Trends Pharmacol Sci , vol.21 , pp. 489-495
    • Susva, M.1    Missbach, M.2    Green, J.3
  • 148
    • 0036554816 scopus 로고    scopus 로고
    • Activated STAT signaling in human tumors provides novel molecular targets for therapeutic intervention
    • Buettner R, Mora LB, Jove R. Activated STAT signaling in human tumors provides novel molecular targets for therapeutic intervention. Clin Cancer Res. 2002;8:945-954.
    • (2002) Clin Cancer Res , vol.8 , pp. 945-954
    • Buettner, R.1    Mora, L.B.2    Jove, R.3
  • 149
    • 5444237088 scopus 로고    scopus 로고
    • STAT proteins as novel targets for cancer drug discovery
    • Turkson J. STAT proteins as novel targets for cancer drug discovery. Expert Opin Ther Targets. 2004;8:409-422.
    • (2004) Expert Opin Ther Targets , vol.8 , pp. 409-422
    • Turkson, J.1
  • 150
    • 0347917184 scopus 로고    scopus 로고
    • Src-dependent phosphorylation of the EGF receptor Tyr-845 mediates Stat-p21waf1 pathway in A431 cells
    • Sato K, Nagao T, Iwasaki T, Nishihira Y, Fukami Y. Src-dependent phosphorylation of the EGF receptor Tyr-845 mediates Stat-p21waf1 pathway in A431 cells. Genes Cells. 2003;8:995-1003.
    • (2003) Genes Cells , vol.8 , pp. 995-1003
    • Sato, K.1    Nagao, T.2    Iwasaki, T.3    Nishihira, Y.4    Fukami, Y.5
  • 151
    • 0042357187 scopus 로고    scopus 로고
    • Src kinases mediate STAT growth pathways in squamous cell carcinoma of the head and neck
    • XiS, Zhang Q, Dyer KF, et al. Src kinases mediate STAT growth pathways in squamous cell carcinoma of the head and neck. J Biol Chem. 2003;278:31574- 31583.
    • (2003) J Biol Chem , vol.278 , pp. 31574-31583
    • Xi, S.1    Zhang, Q.2    Dyer, K.F.3
  • 153
    • 24644457736 scopus 로고    scopus 로고
    • Targeting Stat3 blocks both H1F-1 and VEGF expression induced by multiple oncogenic growth signaling pathways
    • Xu Q, Briggs J, Park S, et al. Targeting Stat3 blocks both H1F-1 and VEGF expression induced by multiple oncogenic growth signaling pathways. Oncogene. 2005;24:5552-5560.
    • (2005) Oncogene , vol.24 , pp. 5552-5560
    • Xu, Q.1    Briggs, J.2    Park, S.3
  • 154
    • 16344380754 scopus 로고    scopus 로고
    • A low-molecular-weight compound discovered through virtual database screening inhibits Stat3 function in breast cancer cells
    • Song H, Wang R, Wang S, Lin J. A low-molecular-weight compound discovered through virtual database screening inhibits Stat3 function in breast cancer cells. Proc Natl Acad Sci U S A. 2005;102:4700-4705.
    • (2005) Proc Natl Acad Sci U S A , vol.102 , pp. 4700-4705
    • Song, H.1    Wang, R.2    Wang, S.3    Lin, J.4
  • 155
    • 0141960055 scopus 로고    scopus 로고
    • Nuclear translocation of phosphorylated STAT3 is essential for vascular endothelial growth factor-induced human dermal microvascular endothelial cell migration and tube formation
    • Yahata Y, Shirakata Y, Tokumaru S, et al. Nuclear translocation of phosphorylated STAT3 is essential for vascular endothelial growth factor-induced human dermal microvascular endothelial cell migration and tube formation. J Biol Chem. 2003;278:40026-40031.
    • (2003) J Biol Chem , vol.278 , pp. 40026-40031
    • Yahata, Y.1    Shirakata, Y.2    Tokumaru, S.3
  • 156
    • 0141596941 scopus 로고    scopus 로고
    • Overview: Translating Hsp90 biology into Hsp90 drugs
    • Workman P. Overview: translating Hsp90 biology into Hsp90 drugs. Curr Cancer Drug Targets. 2003;3:297-300.
    • (2003) Curr Cancer Drug Targets , vol.3 , pp. 297-300
    • Workman, P.1
  • 157
    • 4344674482 scopus 로고    scopus 로고
    • Targeting multiple signal transduction pathways through inhibition of Hsp90
    • Zhang H, Burrows F. Targeting multiple signal transduction pathways through inhibition of Hsp90. J Mol Med. 2004;82:488-499.
    • (2004) J Mol Med , vol.82 , pp. 488-499
    • Zhang, H.1    Burrows, F.2
  • 158
    • 20144375312 scopus 로고    scopus 로고
    • Phase I and pharmacologic study of 17-(allylamino)-17- demethoxygeldanamycin in adult patients with solid tumors
    • Grem JL, Morrison G, Guo XD, et al. Phase I and pharmacologic study of 17-(allylamino)-17-demethoxygeldanamycin in adult patients with solid tumors. J Clin Oncol. 2005;23:1885-1893.
    • (2005) J Clin Oncol , vol.23 , pp. 1885-1893
    • Grem, J.L.1    Morrison, G.2    Guo, X.D.3
  • 159
    • 20944444881 scopus 로고    scopus 로고
    • Phase I pharmacokinetic-pharmacodynamic study of 17-(allylamino)-17- demethoxygeldanamycin (17AAG, NSC 330507), a novel inhibitor of heat shock protein 90, in patients with refractory advanced cancers
    • Ramanathan RK, Trump DL, Eiseman JL, et al. Phase I pharmacokinetic- pharmacodynamic study of 17-(allylamino)-17-demethoxygeldanamycin (17AAG, NSC 330507), a novel inhibitor of heat shock protein 90, in patients with refractory advanced cancers. Clin Cancer Res. 2005;11:3385-3391.
    • (2005) Clin Cancer Res , vol.11 , pp. 3385-3391
    • Ramanathan, R.K.1    Trump, D.L.2    Eiseman, J.L.3
  • 160
    • 23044441106 scopus 로고    scopus 로고
    • Phase I pharmacokinetic and pharmacodynamic study of 17-allylamino, 17-demethoxygeldanamycin in patients with advanced malignancies
    • Banerji U, O'Donnell A, Scurr M, et al. Phase I pharmacokinetic and pharmacodynamic study of 17-allylamino, 17-demethoxygeldanamycin in patients with advanced malignancies. J Clin Oncol. 2005;23:4152-4161.
    • (2005) J Clin Oncol , vol.23 , pp. 4152-4161
    • Banerji, U.1    O'Donnell, A.2    Scurr, M.3
  • 161
    • 0036842742 scopus 로고    scopus 로고
    • Heat-shock protein 90 inhibitors as novel cancer chemotherapeutic agents
    • Neckers L, Neckers K. Heat-shock protein 90 inhibitors as novel cancer chemotherapeutic agents. Expert Opin Emerg Drugs. 2002;7:277-288.
    • (2002) Expert Opin Emerg Drugs , vol.7 , pp. 277-288
    • Neckers, L.1    Neckers, K.2
  • 162
    • 1142273472 scopus 로고    scopus 로고
    • Altered states: Selectively drugging the Hsp90 cancer chaperone
    • Workman P. Altered states: selectively drugging the Hsp90 cancer chaperone. Trends Mol Med. 2004;10:47-51.
    • (2004) Trends Mol Med , vol.10 , pp. 47-51
    • Workman, P.1
  • 163
    • 3242670482 scopus 로고    scopus 로고
    • Antiangiogenic properties of 17-(dimethylaminoethylamino)-17- demethoxygeldanamycin: An orally bioavailable heat shock protein 90 modulator
    • Kaur G, Belotti D, Burger AM, et al. Antiangiogenic properties of 17-(dimethylaminoethylamino)-17-demethoxygeldanamycin: an orally bioavailable heat shock protein 90 modulator. Clin Cancer Res. 2004;10:4813-4821.
    • (2004) Clin Cancer Res , vol.10 , pp. 4813-4821
    • Kaur, G.1    Belotti, D.2    Burger, A.M.3
  • 164
    • 20344407540 scopus 로고    scopus 로고
    • Colorectal cancer and antiangiogenic therapy: What can be expected in clinical practice?
    • Mancuso A, Sternberg CN. Colorectal cancer and antiangiogenic therapy: what can be expected in clinical practice? Crit Rev Oncol Hematol. 2005;55:67-81.
    • (2005) Crit Rev Oncol Hematol , vol.55 , pp. 67-81
    • Mancuso, A.1    Sternberg, C.N.2
  • 165
    • 19444378359 scopus 로고    scopus 로고
    • Use of angiogenesis inhibitors in tumour treatment
    • Fayette J, Soria JC, Armand JP. Use of angiogenesis inhibitors in tumour treatment. Eur J Cancer. 2005;41:1109-1116.
    • (2005) Eur J Cancer , vol.41 , pp. 1109-1116
    • Fayette, J.1    Soria, J.C.2    Armand, J.P.3
  • 166
    • 0033963879 scopus 로고    scopus 로고
    • Treatment of metastatic cancer with tetrathiomolybdate, an anticopper, antiangiogenic agent: Phase I study
    • Brewer GJ, Dick RD, Grover DK, et al. Treatment of metastatic cancer with tetrathiomolybdate, an anticopper, antiangiogenic agent: phase I study. Clin Cancer Res. 2000;6:1-10.
    • (2000) Clin Cancer Res , vol.6 , pp. 1-10
    • Brewer, G.J.1    Dick, R.D.2    Grover, D.K.3


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