Substituted 5,7-Diphenyl-pyrrolo[2,3d]pyrimidines: Potent inhibitors of the tyrosine kinase c-Src

Bioorganic and Medicinal Chemistry Letters

Volumn 10, Issue 9, 2000, Pages 945-949

  Missbach, Martin ^a   Altmann, Eva ^a   Widler, Leo ^a   Šuša, Mira ^a   Buchdunger, Elisabeth ^a   Mett, Helmut ^a   Meyer, Thomas ^a   Green, Jonathan ^a  

^a NOVARTIS PHARMA AG   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

5,7 DIPHENYL PYRROLO (2,3 D) PYRIMIDINE; PROTEIN TYROSINE KINASE; PYRIMIDINE DERIVATIVE; UNCLASSIFIED DRUG;

AMINO ACID SUBSTITUTION; ARTICLE; DRUG ANTAGONISM; DRUG INHIBITION; DRUG POTENCY; DRUG SPECIFICITY; PHOSPHORYLATION;

ANIMALS; BLOTTING, WESTERN; CHICKENS; ENZYME INHIBITORS; MODELS, MOLECULAR; PHOSPHORYLATION; PROTEIN-TYROSINE KINASES; PYRIMIDINES; PYRROLES; STRUCTURE-ACTIVITY RELATIONSHIP; SUBSTRATE SPECIFICITY;

EID: 0034193789     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-894X(00)00131-1     Document Type: Article

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