Local deformations revealed by dynamics simulations of DNA polymerase β with DNA mismatches at the primer terminus

Journal of Molecular Biology

Volumn 321, Issue 3, 2002, Pages 459-478

  Yang, Linjing ^a   Beard, William A ^b   Wilson, Samuel H ^b   Roux, Benoit ^c   Broyde, Suse ^d   Schlick, Tamar ^a  

^a NEW YORK UNIVERSITY   (United States)

^b NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

^c WEILL CORNELL MEDICAL COLLEGE   (United States)

^d NEW YORK UNIVERSITY   (United States)

Author keywords

DNA extension; DNA mispairs; DNA polymerase ; Dynamics simulations; Opening

Indexed keywords

ARGININE; ASPARTIC ACID; DNA; DNA DIRECTED DNA POLYMERASE BETA; EXONUCLEASE;

ARTICLE; BASE MISPAIRING; BINDING SITE; CARBOXY TERMINAL SEQUENCE; CONFORMATION; CRYSTAL STRUCTURE; ENZYME ACTIVE SITE; GEOMETRY; MOLECULAR DYNAMICS; PRIORITY JOURNAL; PROTEIN DNA BINDING; PROTEIN DOMAIN; SIMULATION;

EID: 0036382849     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0022-2836(02)00617-4     Document Type: Article

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