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Volumn 39, Issue 38, 2000, Pages 11571-11580
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Misincorporation by wild-type and mutant T7 RNA polymerases: Identification of interactions that reduce misincorporation rates by stabilizing the catalytically incompetent open conformation
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Author keywords
[No Author keywords available]
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Indexed keywords
NUCLEASE;
RNA POLYMERASE;
AMINO ACID SUBSTITUTION;
ARTICLE;
BACTERIOPHAGE T7;
BASE MISPAIRING;
CATALYSIS;
CONTROLLED STUDY;
CRYSTAL STRUCTURE;
DNA REPLICATION;
DNA TRANSCRIPTION;
ENZYME ACTIVITY;
ENZYME CONFORMATION;
NONHUMAN;
POINT MUTATION;
PRIORITY JOURNAL;
ALANINE;
BACTERIOPHAGE T7;
BASE PAIR MISMATCH;
CATALYSIS;
CYTIDINE TRIPHOSPHATE;
DNA-DIRECTED RNA POLYMERASES;
ENZYME STABILITY;
GLYCINE;
HISTIDINE;
MUTAGENESIS, SITE-DIRECTED;
PHENYLALANINE;
POINT MUTATION;
PROTEIN CONFORMATION;
TRANSCRIPTION, GENETIC;
URIDINE TRIPHOSPHATE;
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EID: 0034718567
PISSN: 00062960
EISSN: None
Source Type: Journal
DOI: 10.1021/bi000579d Document Type: Article |
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Times cited : (91)
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References (39)
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