Evidence for a common binding cavity for three general anesthetics within the GABAA receptor.

The Journal of neuroscience : the official journal of the Society for Neuroscience

Volumn 21, Issue 6, 2001, Pages

  Jenkins, A ^a   Greenblatt, E P ^a   Faulkner, H J ^a   Bertaccini, E ^a   Light, A ^a   Lin, A ^a   Andreasen, A ^a   Viner, A ^a   Trudell, J R ^a   Harrison, N L ^a  

^a WEILL CORNELL MEDICAL COLLEGE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4 AMINOBUTYRIC ACID A RECEPTOR; ANESTHETIC AGENT; CHLOROFORM; HALOTHANE; ISOFLURANE;

ARTICLE; BINDING SITE; CELL LINE; CHEMISTRY; CYTOLOGY; DOSE RESPONSE; DRUG EFFECT; GENETIC TRANSFECTION; GENETICS; HUMAN; KIDNEY; METABOLISM; PATCH CLAMP; SITE DIRECTED MUTAGENESIS; STRUCTURE ACTIVITY RELATION;

ANESTHETICS; BINDING SITES; CELL LINE; CHLOROFORM; DOSE-RESPONSE RELATIONSHIP, DRUG; HALOTHANE; HUMANS; ISOFLURANE; KIDNEY; MUTAGENESIS, SITE-DIRECTED; PATCH-CLAMP TECHNIQUES; RECEPTORS, GABA-A; STRUCTURE-ACTIVITY RELATIONSHIP; TRANSFECTION;

MLCS; MLOWN;

EID: 0035869928     PISSN: None     EISSN: 15292401     Source Type: Journal    
DOI: 10.1523/jneurosci.21-06-j0002.2001     Document Type: Article

References (0)