A single glycine residue at the entrance to the first membrane-spanning domain of the γ-aminobutyric acid type a receptor β2 subunit affects allosteric sensitivity to GABA and anesthetics

Molecular Pharmacology

Volumn 57, Issue 3, 2000, Pages 474-484

  Carlson, Berit X ^a   Engblom, A Christine ^a   Kristiansen, Uffe ^a   Schousboe, Arne ^a   Olsen, Richard W ^b  

^a UNIVERSITY OF COPENHAGEN   (Denmark)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4 AMINOBUTYRIC ACID; 4 AMINOBUTYRIC ACID A RECEPTOR; ALFAXALONE; ANESTHETIC AGENT; ETOMIDATE; FLUNITRAZEPAM; GLYCINE; ION CHANNEL; MUSCIMOL; PENTOBARBITAL; PROPOFOL; RECEPTOR SUBUNIT; TRITIUM;

AMINO ACID SEQUENCE; ANESTHESIA MECHANISM; ARTICLE; CONTROLLED STUDY; DRUG RECEPTOR BINDING; LEPIDOPTERA; NEUROTRANSMISSION; NONHUMAN; POINT MUTATION; PRIORITY JOURNAL; SITE DIRECTED MUTAGENESIS;

EID: 0034006474     PISSN: 0026895X     EISSN: None     Source Type: Journal    
DOI: 10.1124/mol.57.3.474     Document Type: Article

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