-
3
-
-
0036480194
-
Emerging structure of the nicotinic acetylcholine receptors
-
Karlin A. Emerging structure of the nicotinic acetylcholine receptors. Nat. Rev. Neurosci. 3:2002;102-114
-
(2002)
Nat. Rev. Neurosci.
, vol.3
, pp. 102-114
-
-
Karlin, A.1
-
4
-
-
0025393751
-
Molecular biology of GABAA receptors
-
Olsen R.W., Tobin A.J. Molecular biology of GABAA receptors. FASEB J. 4:1990;1469-1480
-
(1990)
FASEB J.
, vol.4
, pp. 1469-1480
-
-
Olsen, R.W.1
Tobin, A.J.2
-
6
-
-
0038209584
-
Unique general anesthetic binding sites within distinct conformational states of the nicotinic acetylcholine receptor
-
Arias H.R., Kem W.R., Trudell J.R., Blanton M.P. Unique general anesthetic binding sites within distinct conformational states of the nicotinic acetylcholine receptor. Int. Rev. Neurobiol. 54:2003;1-50
-
(2003)
Int. Rev. Neurobiol.
, vol.54
, pp. 1-50
-
-
Arias, H.R.1
Kem, W.R.2
Trudell, J.R.3
Blanton, M.P.4
-
7
-
-
0037448581
-
Coupling of agonist binding to channel gating in the GABAA receptor
-
Kash T.L., Jenkins A., Kelley J.C., Trudell J.R., Harrison N.L. Coupling of agonist binding to channel gating in the GABAA receptor. Nature. 421:2003;421-425
-
(2003)
Nature
, vol.421
, pp. 421-425
-
-
Kash, T.L.1
Jenkins, A.2
Kelley, J.C.3
Trudell, J.R.4
Harrison, N.L.5
-
8
-
-
0036062998
-
Molecular modelling of specific and non-specific anaesthetic interactions
-
Trudell J.R., Bertaccini E. Molecular modelling of specific and non-specific anaesthetic interactions. Br. J. Anaesth. 89:2002;32-40
-
(2002)
Br. J. Anaesth.
, vol.89
, pp. 32-40
-
-
Trudell, J.R.1
Bertaccini, E.2
-
9
-
-
0036733135
-
Anesthetic and ethanol effects on spontaneously opening glycine receptor channels
-
Beckstead M.J., Phelan R., Trudell J.R., Bianchini M.J., Mihic S.J. Anesthetic and ethanol effects on spontaneously opening glycine receptor channels. J. Neurochem. 82:2002;1343-1351
-
(2002)
J. Neurochem.
, vol.82
, pp. 1343-1351
-
-
Beckstead, M.J.1
Phelan, R.2
Trudell, J.R.3
Bianchini, M.J.4
Mihic, S.J.5
-
10
-
-
0037144124
-
Unique assignment of inter-subunit association in GABAa alpha1 beta3 gamma2 receptors determined by molecular modeling
-
Trudell J.R. Unique assignment of inter-subunit association in GABAa alpha1 beta3 gamma2 receptors determined by molecular modeling. Biochim. Biophys. Acta. 1565:2002;91-96
-
(2002)
Biochim. Biophys. Acta
, vol.1565
, pp. 91-96
-
-
Trudell, J.R.1
-
11
-
-
0035902009
-
Crystal structure of an ACh-binding protein reveals the ligand-binding domain of nicotinic receptors
-
Brejc K., van Dijk W.J., Klaassen R.V., Schuurmans M., van Der O.J., Smit A.B., Sixma T.K. Crystal structure of an ACh-binding protein reveals the ligand-binding domain of nicotinic receptors. Nature. 411:2001;269-276
-
(2001)
Nature
, vol.411
, pp. 269-276
-
-
Brejc, K.1
Van Dijk, W.J.2
Klaassen, R.V.3
Schuurmans, M.4
Van Der, O.J.5
Smit, A.B.6
Sixma, T.K.7
-
12
-
-
0038112088
-
Structure and gating mechanism of the acetylcholine receptor pore
-
Miyazawa A., Fujiyoshi Y., Unwin N. Structure and gating mechanism of the acetylcholine receptor pore. Nature. 424:2003;949-955
-
(2003)
Nature
, vol.424
, pp. 949-955
-
-
Miyazawa, A.1
Fujiyoshi, Y.2
Unwin, N.3
-
13
-
-
18144447465
-
Redox-coupled crystal structural changes in bovine heart cytochrome c oxidase
-
Yoshikawa S., Shinzawa-Itoh K., Nakashima R., Yaono R., Yamashita E., Inoue N., Yao M., Fei M.J., Libeu C.P., Mizushima T., Yamaguchi H., Tomizaki T., Tsukihara T. Redox-coupled crystal structural changes in bovine heart cytochrome c oxidase. Science. 280:1998;1723-1729
-
(1998)
Science
, vol.280
, pp. 1723-1729
-
-
Yoshikawa, S.1
Shinzawa-Itoh, K.2
Nakashima, R.3
Yaono, R.4
Yamashita, E.5
Inoue, N.6
Yao, M.7
Fei, M.J.8
Libeu, C.P.9
Mizushima, T.10
Yamaguchi, H.11
Tomizaki, T.12
Tsukihara, T.13
-
14
-
-
0032545321
-
Structure of the MscL homolog from mycobacterium tuberculosis: A gated mechanosensitive ion channel
-
Chang G., Spencer R.H., Lee A.T., Barclay M.T., Rees D.C. Structure of the MscL homolog from mycobacterium tuberculosis: a gated mechanosensitive ion channel. Science. 282:1998;2220-2226
-
(1998)
Science
, vol.282
, pp. 2220-2226
-
-
Chang, G.1
Spencer, R.H.2
Lee, A.T.3
Barclay, M.T.4
Rees, D.C.5
-
15
-
-
0028326435
-
Identifying the lipid-protein interface of the torpedo nicotinic acetylcholine receptor: Secondary structure implications
-
Blanton M.P., Cohen J.B. Identifying the lipid-protein interface of the torpedo nicotinic acetylcholine receptor: secondary structure implications. Biochemistry. 33:1994;2859-2872
-
(1994)
Biochemistry
, vol.33
, pp. 2859-2872
-
-
Blanton, M.P.1
Cohen, J.B.2
-
16
-
-
0036019297
-
Predicting the transmembrane secondary structure of ligand-gated ion channels
-
Bertaccini E., Trudell J.R. Predicting the transmembrane secondary structure of ligand-gated ion channels. Protein Eng. 15:2002;443-453
-
(2002)
Protein Eng.
, vol.15
, pp. 443-453
-
-
Bertaccini, E.1
Trudell, J.R.2
-
17
-
-
0035968206
-
Structure of the pore-forming transmembrane domain of a ligand-gated ion channel
-
Methot N., Ritchie B.D., Blanton M.P., Baenziger J.E. Structure of the pore-forming transmembrane domain of a ligand-gated ion channel. J. Biol. Chem. 276:2001;23726-23732
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 23726-23732
-
-
Methot, N.1
Ritchie, B.D.2
Blanton, M.P.3
Baenziger, J.E.4
-
18
-
-
0035237928
-
Molecular modeling of the transmembrane regions of ligand-gated ion channels: Progress and challenges
-
Bertaccini E., Trudell J.R. Molecular modeling of the transmembrane regions of ligand-gated ion channels: progress and challenges. Int. Rev. Neurobiol. 48:2001;141-166
-
(2001)
Int. Rev. Neurobiol.
, vol.48
, pp. 141-166
-
-
Bertaccini, E.1
Trudell, J.R.2
-
19
-
-
0033433846
-
SeqFold. Fully automated fold recognition and modeling software. Evaluation and application
-
Olszewski K., Yan L., Edwards D.J. SeqFold. Fully automated fold recognition and modeling software. Evaluation and application. Theor. Chem. Acc. 101:1999;57-61
-
(1999)
Theor. Chem. Acc.
, vol.101
, pp. 57-61
-
-
Olszewski, K.1
Yan, L.2
Edwards, D.J.3
-
21
-
-
0027506299
-
Nicotinic acetylcholine receptor at 9 a resolution
-
Unwin N. Nicotinic acetylcholine receptor at 9 A resolution. J. Mol. Biol. 229:1993;1101-1124
-
(1993)
J. Mol. Biol.
, vol.229
, pp. 1101-1124
-
-
Unwin, N.1
-
22
-
-
0036304564
-
Activation of the nicotinic acetylcholine receptor involves a switch in conformation of the alpha subunits
-
Unwin N., Miyazawa A., Li J., Fujiyoshi Y. Activation of the nicotinic acetylcholine receptor involves a switch in conformation of the alpha subunits. J. Mol. Biol. 319:2002;1165-1176
-
(2002)
J. Mol. Biol.
, vol.319
, pp. 1165-1176
-
-
Unwin, N.1
Miyazawa, A.2
Li, J.3
Fujiyoshi, Y.4
-
23
-
-
0037441504
-
Rapsyn-mediated clustering of acetylcholine receptor subunits requires the major cytoplasmic loop of the receptor subunits
-
Huebsch K.A., Maimone M.M. Rapsyn-mediated clustering of acetylcholine receptor subunits requires the major cytoplasmic loop of the receptor subunits. J. Neurobiol. 54:2003;486-501
-
(2003)
J. Neurobiol.
, vol.54
, pp. 486-501
-
-
Huebsch, K.A.1
Maimone, M.M.2
-
24
-
-
0031877725
-
Modelling and simulation of ion channels: Applications to the nicotinic acetylcholine receptor
-
Sansom M.S.P., Adcock C., Smith G.R. Modelling and simulation of ion channels: applications to the nicotinic acetylcholine receptor. J. Struct. Biol. 121:1998;246-262
-
(1998)
J. Struct. Biol.
, vol.121
, pp. 246-262
-
-
Sansom, M.S.P.1
Adcock, C.2
Smith, G.R.3
-
26
-
-
12244294449
-
Pores formed by the nicotinic receptor m2delta peptide: A molecular dynamics simulation study
-
Law R.J., Tieleman D.P., Sansom M.S.P. Pores formed by the nicotinic receptor m2delta peptide: a molecular dynamics simulation study. Biophys. J. 84:2003;14-27
-
(2003)
Biophys. J.
, vol.84
, pp. 14-27
-
-
Law, R.J.1
Tieleman, D.P.2
Sansom, M.S.P.3
-
27
-
-
0036286167
-
NMR structures of the second transmembrane domain of the human glycine receptor alpha(1) subunit: Model of pore architecture and channel gating
-
Tang P., Mandal P.K., Xu Y. NMR structures of the second transmembrane domain of the human glycine receptor alpha(1) subunit: model of pore architecture and channel gating. Biophys. J. 83:2002;252-262
-
(2002)
Biophys. J.
, vol.83
, pp. 252-262
-
-
Tang, P.1
Mandal, P.K.2
Xu, Y.3
-
28
-
-
0032919444
-
Structures of the M2 channel-lining segments from nicotinic acetylcholine and NMDA receptors by NMR spectroscopy
-
Opella S.J., Marassi F.M., Gesell J.J., Valente A.P., Kim Y., Oblatt-Montal M., Montal M. Structures of the M2 channel-lining segments from nicotinic acetylcholine and NMDA receptors by NMR spectroscopy. Nat. Struct. Biol. 6:1999;374-379
-
(1999)
Nat. Struct. Biol.
, vol.6
, pp. 374-379
-
-
Opella, S.J.1
Marassi, F.M.2
Gesell, J.J.3
Valente, A.P.4
Kim, Y.5
Oblatt-Montal, M.6
Montal, M.7
-
29
-
-
0024460245
-
A possible model for the inner wall of the acetylcholine receptor channel
-
Furois-Corbin S., Pullman A. A possible model for the inner wall of the acetylcholine receptor channel. Biochim. Biophys. Acta. 984:1989;339-350
-
(1989)
Biochim. Biophys. Acta
, vol.984
, pp. 339-350
-
-
Furois-Corbin, S.1
Pullman, A.2
-
30
-
-
0036086351
-
The alpha-helix and the organization and gating of channels
-
Spencer R.H., Rees D.C. The alpha-helix and the organization and gating of channels. Annu. Rev. Biophys. Biomol. Struct. 31:2002;207-233
-
(2002)
Annu. Rev. Biophys. Biomol. Struct.
, vol.31
, pp. 207-233
-
-
Spencer, R.H.1
Rees, D.C.2
-
31
-
-
0034870592
-
Interaction of barbiturate analogs with the torpedo californica nicotinic acetylcholine receptor ion channel
-
Arias H.R., McCardy E.A., Gallagher M.J., Blanton M.P. Interaction of barbiturate analogs with the torpedo californica nicotinic acetylcholine receptor ion channel. Mol. Pharmacol. 60:2001;497-506
-
(2001)
Mol. Pharmacol.
, vol.60
, pp. 497-506
-
-
Arias, H.R.1
McCardy, E.A.2
Gallagher, M.J.3
Blanton, M.P.4
-
32
-
-
0038746854
-
Noncompetitive antagonist binding sites in the torpedo nicotinic acetylcholine receptor ion channel. Structure-activity relationship studies using adamantane derivatives
-
Arias H.R., Trudell J.R., Bayer E.Z., Hester B., McCardy E.A., Blanton M.P. Noncompetitive antagonist binding sites in the torpedo nicotinic acetylcholine receptor ion channel. Structure-activity relationship studies using adamantane derivatives. Biochemistry. 42:2003;7358-7370
-
(2003)
Biochemistry
, vol.42
, pp. 7358-7370
-
-
Arias, H.R.1
Trudell, J.R.2
Bayer, E.Z.3
Hester, B.4
McCardy, E.A.5
Blanton, M.P.6
-
33
-
-
0027987062
-
Identification of acetylcholine receptor channel-lining residues in the entire M2 segment of the a subunit
-
Akabas M.H., Kaufmann C., Archdeacon P., Karlin A. Identification of acetylcholine receptor channel-lining residues in the entire M2 segment of the a subunit. Neuron. 13:1994;919-927
-
(1994)
Neuron
, vol.13
, pp. 919-927
-
-
Akabas, M.H.1
Kaufmann, C.2
Archdeacon, P.3
Karlin, A.4
-
34
-
-
0032102496
-
The location of the gate in the acetylcholine receptor channel
-
Wilson G.G., Karlin A. The location of the gate in the acetylcholine receptor channel. Neuron. 20:1998;1269-1281
-
(1998)
Neuron
, vol.20
, pp. 1269-1281
-
-
Wilson, G.G.1
Karlin, A.2
-
36
-
-
0033548061
-
Using loop length variants to dissect the folding pathway of a four-helix-bundle protein
-
Nagi A.D., Anderson K.S., Regan L. Using loop length variants to dissect the folding pathway of a four-helix-bundle protein. J. Mol. Biol. 286:1999;257-265
-
(1999)
J. Mol. Biol.
, vol.286
, pp. 257-265
-
-
Nagi, A.D.1
Anderson, K.S.2
Regan, L.3
-
37
-
-
0038457745
-
Molecular dynamics simulations to determine the optimal loop length in the helix-loop-helix motif
-
Liu H.L., Shu Y.C., Wu Y.H. Molecular dynamics simulations to determine the optimal loop length in the helix-loop-helix motif. J. Biomol. Struct. Dyn. 20:2003;741-745
-
(2003)
J. Biomol. Struct. Dyn.
, vol.20
, pp. 741-745
-
-
Liu, H.L.1
Shu, Y.C.2
Wu, Y.H.3
-
38
-
-
0032502674
-
Probing the structure of the nicotinic acetylcholine receptor ion channel with the uncharged photoactivable compound 2-[3H]diazofluorene
-
Blanton M.P., Dangott L.J., Raja S.K., Lala A.K., Cohen J.B. Probing the structure of the nicotinic acetylcholine receptor ion channel with the uncharged photoactivable compound 2-[3H]diazofluorene. J. Biol. Chem. 273:1998;8659-8668
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 8659-8668
-
-
Blanton, M.P.1
Dangott, L.J.2
Raja, S.K.3
Lala, A.K.4
Cohen, J.B.5
-
39
-
-
0028809730
-
Identification of acetylcholine receptor channel-lining residues in the M1 segment of the α-subunit
-
Akabas M.H., Karlin A. Identification of acetylcholine receptor channel-lining residues in the M1 segment of the α-subunit. Biochemistry. 34:1995;12496-12500
-
(1995)
Biochemistry
, vol.34
, pp. 12496-12500
-
-
Akabas, M.H.1
Karlin, A.2
-
40
-
-
0034006474
-
A single glycine residue at the entrance to the first membrane-spanning domain of the gamma-aminobutyric acid type a receptor beta(2) subunit affects allosteric sensitivity to GABA and anesthetics
-
Carlson B.X., Engblom A.C., Kristiansen U., Schousboe A., Olsen R.W. A single glycine residue at the entrance to the first membrane-spanning domain of the gamma-aminobutyric acid type A receptor beta(2) subunit affects allosteric sensitivity to GABA and anesthetics. Mol. Pharmacol. 57:2000;474-484
-
(2000)
Mol. Pharmacol.
, vol.57
, pp. 474-484
-
-
Carlson, B.X.1
Engblom, A.C.2
Kristiansen, U.3
Schousboe, A.4
Olsen, R.W.5
-
41
-
-
0035869928
-
Evidence for a common binding cavity for three general anesthetics within the GABAA receptor
-
Jenkins A., Greenblatt E.P., Faulkner H.J., Bertaccini E., Light A., Lin A., Andreasen A., Viner A., Trudell J.R., Harrison N.L. Evidence for a common binding cavity for three general anesthetics within the GABAA receptor. J. Neurosci. 21:2001;RC136
-
(2001)
J. Neurosci.
, vol.21
, pp. 136
-
-
Jenkins, A.1
Greenblatt, E.P.2
Faulkner, H.J.3
Bertaccini, E.4
Light, A.5
Lin, A.6
Andreasen, A.7
Viner, A.8
Trudell, J.R.9
Harrison, N.L.10
-
42
-
-
0035042719
-
Protein mobility and GABA-induced conformational changes in GABA(A) receptor pore-lining M2 segment
-
Horenstein J., Wagner D.A., Czajkowski C., Akabas M.H. Protein mobility and GABA-induced conformational changes in GABA(A) receptor pore-lining M2 segment. Nat. Neurosci. 4:2001;477-485
-
(2001)
Nat. Neurosci.
, vol.4
, pp. 477-485
-
-
Horenstein, J.1
Wagner, D.A.2
Czajkowski, C.3
Akabas, M.H.4
-
43
-
-
1842328604
-
Sites of alcohol and volatile anaesthetic action on GABA(A) and glycine receptors
-
Mihic S.J., Ye Q., Wick M.J., Koltchine V.V., Krasowski M.D., Finn S.E., Mascia M.P., Valenzuela C.F., Hanson K.K., Greenblatt E.P., Harris R.A., Harrison N.L. Sites of alcohol and volatile anaesthetic action on GABA(A) and glycine receptors. Nature. 389:1997;385-389
-
(1997)
Nature
, vol.389
, pp. 385-389
-
-
Mihic, S.J.1
Ye, Q.2
Wick, M.J.3
Koltchine, V.V.4
Krasowski, M.D.5
Finn, S.E.6
Mascia, M.P.7
Valenzuela, C.F.8
Hanson, K.K.9
Greenblatt, E.P.10
Harris, R.A.11
Harrison, N.L.12
-
44
-
-
0032568547
-
Mutations of GABA and glycine receptors change alcohol cutoff: Evidence for an alcohol receptor
-
Wick M.J., Mihic S.J., Ueno S., Mascia M.P., Trudell J.R., Brozowski S.J., Ye Q., Harrison N.L., Harris R.A. Mutations of GABA and glycine receptors change alcohol cutoff: evidence for an alcohol receptor. Proc. Natl. Acad. Sci. U.S.A. 95:1998;6504-6509
-
(1998)
Proc. Natl. Acad. Sci. U.S.A.
, vol.95
, pp. 6504-6509
-
-
Wick, M.J.1
Mihic, S.J.2
Ueno, S.3
Mascia, M.P.4
Trudell, J.R.5
Brozowski, S.J.6
Ye, Q.7
Harrison, N.L.8
Harris, R.A.9
-
45
-
-
0034255021
-
Specific binding sites for alcohols and anesthetics on ligand-gated ion channels
-
Mascia M.P., Trudell J.R., Harris R.A. Specific binding sites for alcohols and anesthetics on ligand-gated ion channels. Proc. Natl. Acad. Sci. U.S.A. 97:2000;9305-9310
-
(2000)
Proc. Natl. Acad. Sci. U.S.A.
, vol.97
, pp. 9305-9310
-
-
Mascia, M.P.1
Trudell, J.R.2
Harris, R.A.3
-
46
-
-
0032750784
-
GABA increases the water-accessibility of M3 membrane-spanning residues in GABA-A receptors
-
Williams D.B., Akabas M.H. GABA increases the water-accessibility of M3 membrane-spanning residues in GABA-A receptors. Biophys. J. 77:1999;2563-2574
-
(1999)
Biophys. J.
, vol.77
, pp. 2563-2574
-
-
Williams, D.B.1
Akabas, M.H.2
-
47
-
-
0033363317
-
Acetylcholine receptor M3 domain: Stereochemical and volume contributions to channel gating
-
Wang H.L., Milone M., Ohno K., Shen X.M., Tsujino A., Batocchi A.P., Tonali P., Brengman J., Engel A.G., Sine S.M. Acetylcholine receptor M3 domain: stereochemical and volume contributions to channel gating. Nat. Neurosci. 2:1999;226-233
-
(1999)
Nat. Neurosci.
, vol.2
, pp. 226-233
-
-
Wang, H.L.1
Milone, M.2
Ohno, K.3
Shen, X.M.4
Tsujino, A.5
Batocchi, A.P.6
Tonali, P.7
Brengman, J.8
Engel, A.G.9
Sine, S.M.10
-
48
-
-
0024278441
-
Annular and nonannular binding sites for cholesterol associated with the nicotinic acetylcholine receptor
-
Jones O.T., McNamee M. Annular and nonannular binding sites for cholesterol associated with the nicotinic acetylcholine receptor. Biochemistry. 27:1988;2364-2374
-
(1988)
Biochemistry
, vol.27
, pp. 2364-2374
-
-
Jones, O.T.1
McNamee, M.2
-
49
-
-
0032508916
-
Identifying the cholesterol binding domain in the nicotinic acetylcholine receptor with[125I]azido-cholesterol
-
Corbin J., Wang H.H., Blanton M.P. Identifying the cholesterol binding domain in the nicotinic acetylcholine receptor with[125I]azido-cholesterol. Biochim. Biophys. Acta. 1414:1998;65-74
-
(1998)
Biochim. Biophys. Acta
, vol.1414
, pp. 65-74
-
-
Corbin, J.1
Wang, H.H.2
Blanton, M.P.3
-
50
-
-
0023667077
-
Effects of substitution of putative transmembrane segments on nicotinic acetylcholine receptor function
-
Tobimatsu T., Fujita Y., Fukuda K., Tanaka K., Mori Y., Konno T., Mishina M., Numa S. Effects of substitution of putative transmembrane segments on nicotinic acetylcholine receptor function. FEBS Lett. 222:1987;56-62
-
(1987)
FEBS Lett.
, vol.222
, pp. 56-62
-
-
Tobimatsu, T.1
Fujita, Y.2
Fukuda, K.3
Tanaka, K.4
Mori, Y.5
Konno, T.6
Mishina, M.7
Numa, S.8
-
51
-
-
0032772075
-
Alteration in ion channel function of mouse nicotinic acetylcholine receptor by mutations in the M4 transmembrane domain
-
Tamamizu S., Lee Y.H., Hung B., McNamee M., Lasalde-Dominicci J.A. Alteration in ion channel function of mouse nicotinic acetylcholine receptor by mutations in the M4 transmembrane domain. J. Membr. Biol. 170:1999;157-164
-
(1999)
J. Membr. Biol.
, vol.170
, pp. 157-164
-
-
Tamamizu, S.1
Lee, Y.H.2
Hung, B.3
McNamee, M.4
Lasalde-Dominicci, J.A.5
-
52
-
-
0036754362
-
Tryptophan scanning mutagenesis in TM4 of the GABA(A) receptor alpha1 subunit: Implications for modulation by inhaled anesthetics and ion channel structure
-
Jenkins A., Andreasen A., Trudell J.R., Harrison N.L. Tryptophan scanning mutagenesis in TM4 of the GABA(A) receptor alpha1 subunit: implications for modulation by inhaled anesthetics and ion channel structure. Neuropharmacology. 43:2002;669-678
-
(2002)
Neuropharmacology
, vol.43
, pp. 669-678
-
-
Jenkins, A.1
Andreasen, A.2
Trudell, J.R.3
Harrison, N.L.4
-
53
-
-
0034059664
-
Nicotinic receptor fourth transmembrane domain: Hydrogen bonding by conserved threonine contributes to channel gating kinetics
-
Bouzat C., Barrantes F.J., Sine S.M. Nicotinic receptor fourth transmembrane domain: hydrogen bonding by conserved threonine contributes to channel gating kinetics. J. Gen. Physiol. 115:2000;663-671
-
(2000)
J. Gen. Physiol.
, vol.115
, pp. 663-671
-
-
Bouzat, C.1
Barrantes, F.J.2
Sine, S.M.3
-
54
-
-
0036629771
-
Identification of threonine 422 in transmembrane domain alpha M4 of the nicotinic acetylcholine receptor as a possible site of interaction with hydrocortisone
-
Garbus I., Roccamo A.M., Barrantes F.J. Identification of threonine 422 in transmembrane domain alpha M4 of the nicotinic acetylcholine receptor as a possible site of interaction with hydrocortisone. Neuropharmacology. 43:2002;65-73
-
(2002)
Neuropharmacology
, vol.43
, pp. 65-73
-
-
Garbus, I.1
Roccamo, A.M.2
Barrantes, F.J.3
-
55
-
-
0028177302
-
The prediction and orientation of alpha-helices from sequence alignments: The combined use of environment-dependent substitution tables, Fourier transform methods and helix capping rules
-
Donnelly D., Overington J.P., Blundell T.L. The prediction and orientation of alpha-helices from sequence alignments: the combined use of environment-dependent substitution tables, Fourier transform methods and helix capping rules. Protein Eng. 7:1994;645-653
-
(1994)
Protein Eng.
, vol.7
, pp. 645-653
-
-
Donnelly, D.1
Overington, J.P.2
Blundell, T.L.3
-
56
-
-
0028070549
-
Parallel helix bundles and ion channels: Molecular modeling via simulated annealing and restrained molecular dynamics
-
Kerr I.D., Sankararamakrishnan R., Smart O.S., Sansom M.S.P. Parallel helix bundles and ion channels: molecular modeling via simulated annealing and restrained molecular dynamics. Biophys. J. 67:1994;1501-1515
-
(1994)
Biophys. J.
, vol.67
, pp. 1501-1515
-
-
Kerr, I.D.1
Sankararamakrishnan, R.2
Smart, O.S.3
Sansom, M.S.P.4
-
57
-
-
0036725277
-
Molecular dynamics simulations of biomolecules
-
Karplus M., McCammon J.A. Molecular dynamics simulations of biomolecules. Nat. Struct. Biol. 9:2002;646-652
-
(2002)
Nat. Struct. Biol.
, vol.9
, pp. 646-652
-
-
Karplus, M.1
McCammon, J.A.2
-
58
-
-
0037044793
-
GABAA receptor M2-M3 loop secondary structure and changes in accessibility during channel gating
-
Bera A.K., Chatav M., Akabas M.H. GABAA receptor M2-M3 loop secondary structure and changes in accessibility during channel gating. J. Biol. Chem. 277:2002;43002-43010
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 43002-43010
-
-
Bera, A.K.1
Chatav, M.2
Akabas, M.H.3
-
59
-
-
0036829836
-
The beta subunit determines the ion selectivity of the GABAA receptor
-
Jensen M.L., Timmermann D.B., Johansen T.H., Schousboe A., Varming T., Ahring P.K. The beta subunit determines the ion selectivity of the GABAA receptor. J. Biol. Chem. 277:2002;41438-41447
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 41438-41447
-
-
Jensen, M.L.1
Timmermann, D.B.2
Johansen, T.H.3
Schousboe, A.4
Varming, T.5
Ahring, P.K.6
-
60
-
-
0038069026
-
Mutations at the GABA receptor selectivity filter: A possible role for effective charges
-
V.E. Wotring, T.S. Miller, D.S. Weiss, Mutations at the GABA receptor selectivity filter: a possible role for effective charges. J. Physiol. 548 (2003) 527-540.
-
(2003)
J. Physiol.
, vol.548
, pp. 527-540
-
-
Wotring, V.E.1
Miller, T.S.2
Weiss, D.S.3
-
61
-
-
0027772476
-
Chimaeric nicotinic-serotonergic receptor combines distinct ligand binding and channel specificities
-
Eisele J.L., Bertrand S., Galzi J.L., Devillers-Thiery A., Changeux J.P., Bertrand D. Chimaeric nicotinic-serotonergic receptor combines distinct ligand binding and channel specificities. Nature. 366:1993;479-483
-
(1993)
Nature
, vol.366
, pp. 479-483
-
-
Eisele, J.L.1
Bertrand, S.2
Galzi, J.L.3
Devillers-Thiery, A.4
Changeux, J.P.5
Bertrand, D.6
-
62
-
-
0034046304
-
Probing the role of a conserved M1 proline residue in 5-hydroxytryptamine(3) receptor gating
-
Dang H., England P.M., Farivar S.S., Dougherty D.A., Lester H.A. Probing the role of a conserved M1 proline residue in 5-hydroxytryptamine(3) receptor gating. Mol. Pharmacol. 57:2000;1114-1122
-
(2000)
Mol. Pharmacol.
, vol.57
, pp. 1114-1122
-
-
Dang, H.1
England, P.M.2
Farivar, S.S.3
Dougherty, D.A.4
Lester, H.A.5
-
63
-
-
0034731271
-
The Croonian Lecture 2000. Nicotinic acetylcholine receptor and the structural basis of fast synaptic transmission
-
Unwin N. The Croonian Lecture 2000. Nicotinic acetylcholine receptor and the structural basis of fast synaptic transmission. Phil. Trans. R. Soc. London B Biol. Sci. 355:2000;1813-1829
-
(2000)
Phil. Trans. R. Soc. London B Biol. Sci.
, vol.355
, pp. 1813-1829
-
-
Unwin, N.1
-
64
-
-
1042301377
-
Charged residues in the {beta}2 subunit involved in GABAA receptor activation
-
Kash T.L., Dizon M.J., Trudell J.R., Harrison N.L. Charged residues in the {beta}2 subunit involved in GABAA receptor activation. J. Biol. Chem. 279:2004;4887-4893
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 4887-4893
-
-
Kash, T.L.1
Dizon, M.J.2
Trudell, J.R.3
Harrison, N.L.4
-
65
-
-
0034725597
-
Arg-274 and Leu-277 of the gamma-aminobutyric acid type a receptor alpha 2 subunit define agonist efficacy and potency
-
O'Shea S.M., Harrison N.L. Arg-274 and Leu-277 of the gamma-aminobutyric acid type A receptor alpha 2 subunit define agonist efficacy and potency. J. Biol. Chem. 275:2000;22764-22768
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 22764-22768
-
-
O'Shea, S.M.1
Harrison, N.L.2
-
66
-
-
0033046008
-
The steroid promegestone is a noncompetitive antagonist of the torpedo nicotinic acetylcholine receptor that interacts with the lipid-protein interface
-
Blanton M.P., Xie Y., Dangott L.J., Cohen J.B. The steroid promegestone is a noncompetitive antagonist of the torpedo nicotinic acetylcholine receptor that interacts with the lipid-protein interface. Mol. Pharmacol. 55:1999;269-278
-
(1999)
Mol. Pharmacol.
, vol.55
, pp. 269-278
-
-
Blanton, M.P.1
Xie, Y.2
Dangott, L.J.3
Cohen, J.B.4
-
67
-
-
0029942862
-
The whole structure of the 13-subunit oxidized cytochrome c oxidase at 2.8 a
-
Tsukihara T., Aoyama H., Yamashita E., Tomizaki T., Yamaguchi H., Shinzawa-Itoh K., Nakashima R., Yaono R., Yoshikawa S. The whole structure of the 13-subunit oxidized cytochrome c oxidase at 2.8 A. Science. 272:1996;1136-1144
-
(1996)
Science
, vol.272
, pp. 1136-1144
-
-
Tsukihara, T.1
Aoyama, H.2
Yamashita, E.3
Tomizaki, T.4
Yamaguchi, H.5
Shinzawa-Itoh, K.6
Nakashima, R.7
Yaono, R.8
Yoshikawa, S.9
-
68
-
-
0035871765
-
The surface accessibility of the glycine receptor M2-M3 loop is increased in the channel open state
-
Lynch J.W., Han N.L., Haddrill J., Pierce K.D., Schofield P.R. The surface accessibility of the glycine receptor M2-M3 loop is increased in the channel open state. J. Neurosci. 21:2001;2589-2599
-
(2001)
J. Neurosci.
, vol.21
, pp. 2589-2599
-
-
Lynch, J.W.1
Han, N.L.2
Haddrill, J.3
Pierce, K.D.4
Schofield, P.R.5
-
69
-
-
0033811476
-
The extracellular linker of muscle acetylcholine receptor channels is a gating control element
-
Grosman C., Salamone F.N., Sine S.M., Auerbach A. The extracellular linker of muscle acetylcholine receptor channels is a gating control element. J. Gen. Physiol. 116:2000;327-340
-
(2000)
J. Gen. Physiol.
, vol.116
, pp. 327-340
-
-
Grosman, C.1
Salamone, F.N.2
Sine, S.M.3
Auerbach, A.4
-
70
-
-
0033529306
-
The solution structure of oxidized Escherichia coli cytochrome b562
-
Arnesano F., Banci L., Bertini I., Faraone-Mennella J., Rosato A., Barker P.D., Fersht A.R. The solution structure of oxidized Escherichia coli cytochrome b562. Biochemistry. 38:1999;8657-8670
-
(1999)
Biochemistry
, vol.38
, pp. 8657-8670
-
-
Arnesano, F.1
Banci, L.2
Bertini, I.3
Faraone-Mennella, J.4
Rosato, A.5
Barker, P.D.6
Fersht, A.R.7
-
71
-
-
0030683493
-
Helix packing angle preferences
-
Bowie J.U. Helix packing angle preferences. Nat. Struct. Biol. 4:1997;915-917
-
(1997)
Nat. Struct. Biol.
, vol.4
, pp. 915-917
-
-
Bowie, J.U.1
-
72
-
-
0019316535
-
Structural and functional diversity in 4-alpha-helical proteins
-
Weber P.C., Salemme F.R. Structural and functional diversity in 4-alpha-helical proteins. Nature. 287:1980;82-84
-
(1980)
Nature
, vol.287
, pp. 82-84
-
-
Weber, P.C.1
Salemme, F.R.2
|