Loose Protein Packing around the Extracellular Half of the GABA A Receptor β1 Subunit M2 Channel-lining Segment

Journal of Biological Chemistry

Volumn 279, Issue 12, 2004, Pages 11198-11205

  Goren, Eric N ^a   Reeves, David C ^a   Akabas, Myles H ^a  

^a ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOASSAY; BIOLOGICAL MEMBRANES; CELLS; WATER;

CHANNEL LININGS; LIGANDS;

PROTEINS;

4 AMINOBUTYRIC ACID; 4 AMINOBUTYRIC ACID A RECEPTOR; CHLOROMERCURIBENZENESULFONIC ACID; CYSTEINE; ION CHANNEL; NICOTINIC RECEPTOR; RECEPTOR SUBUNIT; WATER;

ANIMAL CELL; ARTICLE; CHANNEL GATING; ION CURRENT; NONHUMAN; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTEIN DOMAIN; PROTEIN PROCESSING; PROTEIN STRUCTURE; RAT; REACTION TIME;

4-CHLOROMERCURIBENZENESULFONATE; AMINO ACID SEQUENCE; ANIMALS; CARRIER PROTEINS; CYTOPLASM; GABA PLASMA MEMBRANE TRANSPORT PROTEINS; GAMMA-AMINOBUTYRIC ACID; KINETICS; MEMBRANE PROTEINS; MEMBRANE TRANSPORT PROTEINS; MOLECULAR SEQUENCE DATA; MUTATION; ORGANIC ANION TRANSPORTERS; POLYMERASE CHAIN REACTION; RATS; SEQUENCE HOMOLOGY, AMINO ACID; XENOPUS;

ANIMALIA; TORPEDO;

EID: 1642565156     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M314050200     Document Type: Article

References (62)

1. Rabow, L. E., Russek, S. J., and Farb, D. H. (1995) Synapse 21, 189-274
2. Macdonald, R. L., and Olsen, R. W. (1994) Annu. Rev. Neurosci. 17, 569-602
3. Karlin, A. (2002) Nat. Rev. Neurosci. 3, 102-114
4. Changeux, J., and Edelstein, S. J. (2001) Curr. Opin. Neurobiol. 11, 369-377
5. Reeves, D. C., and Lummis, S. C. (2002) Mol. Membr. Biol. 19, 11-26
6. Chang, Y., Wang, R., Barot, S., and Weiss, D. S. (1996) J. Neurosci. 16, 5415-5424
7. Im, W. B., Pregenzer, J. F., Binder, J. A., Dillon, G. H., and Alberts, G. L. (1995) J. Biol. Chem. 270, 26063-26066
8. Tretter, V., Ehya, N., Fuchs, K, and Sieghart, W. (1997) J. Neurosci. 17, 2728-2737
9. Baumann, S. W., Baur, R., and Sigel, E. (2002) J. Biol. Chem. 277, 46020-46025
10. Karlin, A., and Akabas, M. H. (1995) Neuron 15, 1231-1244
11. Miyazawa, A., Fujiyoshi, Y., and Unwin, N. (2003) Nature 423, 949-955
12. Smith, G. B., and Olsen, R. W. (1994) J. Biol. Chem. 269, 20380-20387
13. Amin, J., and Weiss, D. S. (1993) Nature 366, 565-569
14. Newell, J. G., and Czajkowski, C. (2003) J. Biol. Chem. 278, 13166-13172
15. Xu, M., and Akabas, M. H. (1996) J. Gen. Physiol. 107, 195-205
16. Brejc, K., van Dijk, W. J., Klaassen, R. V., Schuurmans, M., van Der Oost, J., Smit, A. B., and Sixma, T. K. (2001) Nature 411, 269-276
17. Reeves, D. C., Sayed, M. F., Chau, P. L., Price, K. L., and Lummis, S. C. (2003) Biophys. J. 84, 2338-2344
18. Sine, S. M., Wang, H. L., and Bren, N. (2002) J. Biol. Chem. 277, 29210-29223
19. Unwin, N., Miyazawa, A., Li, J., and Fujiyoshi, Y. (2002) J. Mol. Biol. 319, 1165-1176
20. VanSteveninck, J., Weed, R. I., and Rothstein, A. (1965) J. Gen. Physiol. 48, 617-632
21. Olami, Y., Rimon, A., Gerchman, Y., Rothman, A., and Padan, E. (1997) J. Biol. Chem. 272, 1761-1768
22. Hasinoff, B. B., Masden, N. B., and Avramovic-Zikic, O. (1971) Can. J. Biochem. 49, 742-751
23. Miller, C. (1989) Neuron 2, 1195-1205
24. Imoto, K., Busch, C., Sakmann, B., Mishina, M., Konno, T., Nakai, J., Bujo, H., Mori, Y., Fukuda, K., and Numa, S. (1988) Nature 335, 645-648
25. Karlin, A., and Akabas, M. H. (1998) Methods Enzymol. 293, 123-145
26. Akabas, M. H., Kaufmann, C., Archdeacon, P., and Karlin, A. (1994) Neuron 13, 919-927
27. Horenstein, J., and Akabas, M. H. (1998) Mol. Pharmacol. 53, 870-877
28. Zhang, H., and Karlin, A. (1998) Biochemistry 37, 7952-7964
29. Williams, D. B., and Akabas, M. H. (1999) Biophys. J. 77, 2563-2574
30. Reeves, D. C., Goren, E. N., Akabas, M. H., and Lummis, S. C. (2001) J. Biol. Chem. 276, 42035-42042
31. Horenstein, J., Wagner, D. A., Czajkowski, C., and Akabas, M. H. (2001) Nat. Neurosci. 4, 477-485
32. Schreibmayer, W., Lester, H. A., and Dascal, N. (1994) Pflügers Arch. 426, 453-458
33. Bera, A. K., Chatav, M., and Akabas, M. H. (2002) J. Biol. Chem. 277, 43002-43010
34. Mortensen, M., Wafford, K. A., Wingrove, P., and Ebert, B. (2003) Eur. J. Pharmacol. 476, 17-24
35. Thompson, S. A., Smith, M. Z., Wingrove, P. B., Whiting, P. J., and Wafford, K. A. (1999) Br. J. Pharmacol. 127, 1349-1358
36. Dalziel, J. E., Cox, G. B., Gage, P. W., and Birnir, B. (2000) Mol. Pharmacol. 57, 875-882
37. Bianchi, M. T., and Macdonald, R. L. (2001) Neuropharmacology 41, 737-744
38. Akabas, M. H., Stauffer, D. A., Xu, M., and Karlin, A. (1992) Science 258, 307-310
39. Filatov, G. N., and White, M. M. (1995) Mol. Pharmacol. 48, 379-384
40. Labarca, C., Nowak, M. W., Zhang, H., Tang, L., Deshpande, P., and Lester, H. A. (1995) Nature 376, 514-516
41. Chang, Y., and Weiss, D. S. (1998) Mol. Pharmacol. 53, 511-523
42. Burkat, P. M., Yang, J., and Gingrich, K. J. (2001) J. Neurosci. 21, 7026-7036
43. Jones, M. V., and Westbrook, G. L. (1995) Neuron 15, 181-191
44. Twyman, R. E., Rogers, C. J., and Macdonald, R. L. (1990) J. Physiol. (Lond.) 423, 193-220
45. Panicker, S., Cruz, H., Arrabit, C., and Slesinger, P. A. (2002) J. Neurosci. 22, 1629-1639
46. Revah, F., Galzi, J. L., Giraudat, J., Haumont, P. Y., Lederer, F., and Changeux, J. P. (1990) Proc. Natl. Acad. Sci. U. S. A. 87, 4675-4679
47. Charnet, P., Labarca, C., Leonard, R. J., Vogelaar, N. J., Czyzyk, L., Gouin, A., Davidson, N., and Lester, H. A. (1990) Neuron 4, 87-95
48. Shan, Q., Haddrill, J. L., and Lynch, J. W. (2002) J. Biol. Chem. 277, 44845-44853
49. Villarroel, A., Herlitze, S., Koenen, M., and Sakmann, B. (1991) Proc. R. Soc. Lond. B Biol. Sci. 243, 69-74
50. Xu, M., Covey, D. F., and Akabas, M. H. (1995) Biophys. J. 69, 1858-1867
51. Wotring, V. E., Miller, T. S., and Weiss, D. S. (2003) J. Physiol. (Lond.) 548, 527-540
52. Keramidas, A., Moorhouse, A. J., Pierce, K. D., Schofield, P. R., and Barry, P. H. (2002) J. Gen. Physiol. 119, 393-410
53. Gunthorpe, M. J., and Lummis, S. C. (2001) J. Biol. Chem. 276, 10977-10983
54. Corringer, P. J., Bertrand, S., Galzi, J. L., Devillers-Thiery, A., Changeux, J. P., and Bertrand, D. (1999) Neuron 22, 831-843
55. Cymes, G. D., Grosman, C., and Auerbach, A. (2002) Biochemistry 41, 5548-5555
56. White, B. H., and Cohen, J. B. (1992) J. Biol. Chem. 267, 5770-15783
57. Pascual, J. M., and Karlin, A. (1998) J. Gen. Physiol. 111, 717-739
58. Unwin, N. (1995) Nature 373, 37-43
59. Auerbach, A., Sigurdson, W., Chen, J., and Akk, G. (1996) J. Physiol. (Lond.) 494, 155-170
60. Scheller, M., and Forman, S. A. (2002) J. Neurosci. 22, 8411-8421
61. Ueno, S., Lin, A., Nikolaeva, N., Trudell, J. R., Mihic, S. J., Harris, R. A., and Harrison, N. L. (2000) Br. J. Pharmacol. 131, 296-302
62. Wilson, G. G., and Karlin, A. (1998) Neuron 20, 1269-1281