Activation of the nicotinic acetylcholine receptor involves a switch in conformation of the α subunits

Journal of Molecular Biology

Volumn 319, Issue 5, 2002, Pages 1165-1176

  Unwin, N ^a   Miyazawa, A ^b   Li, J ^a   Fujiyoshi, Y ^c,d  

^a MRC LABORATORY OF MOLECULAR BIOLOGY   (United Kingdom)

^b RIKEN HARIMA INSTITUTE   (Japan)

^c KYOTO UNIVERSITY   (Japan)

^d Japan Biological Information Research Center   (Japan)

Author keywords

Acetylcholine receptor; Activation; Electron microscopy; Extracellular domain; Ion channel

Indexed keywords

ACETYLCHOLINE BINDING PROTEIN; BINDING PROTEIN; NICOTINIC RECEPTOR; RECEPTOR SUBUNIT; UNCLASSIFIED DRUG;

ALPHA CHAIN; ARTICLE; ELECTRON MICROSCOPY; LIGAND BINDING; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN DOMAIN; PROTEIN SECONDARY STRUCTURE; ROTATION; STRUCTURE ANALYSIS;

EID: 0036304564     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0022-2836(02)00381-9     Document Type: Article

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