메뉴 건너뛰기




Volumn 1, Issue , 2001, Pages

Peroxisome proliferator-activated receptor agonists prevent 25-OH-cholesterol induced c-jun activation and cell death

Author keywords

[No Author keywords available]

Indexed keywords

15 DEOXY DELTA12,14 PROSTAGLANDIN J2; 25 HYDROXYCHOLESTEROL; CELL NUCLEUS RECEPTOR; IBUPROFEN; INDOMETACIN; MITOGEN ACTIVATED PROTEIN KINASE; OXYSTEROL; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR AGONIST; PIRINIXIC ACID; PROTEIN C JUN; STRESS ACTIVATED PROTEIN KINASE; SYNAPTOPHYSIN;

EID: 2642559661     PISSN: 14712210     EISSN: None     Source Type: Journal    
DOI: 10.1186/1471-2210-1-10     Document Type: Article
Times cited : (11)

References (66)
  • 1
    • 0031048299 scopus 로고    scopus 로고
    • Conner Memorial Lecture: Oxidative modification of LDL and atherogenesis
    • Steinberg D: Lewis A. Conner Memorial Lecture: Oxidative modification of LDL and atherogenesis. Circulation 1997, 95:1062-1071
    • (1997) Circulation , vol.95 , pp. 1062-1071
    • Steinberg, D.1    Lewis, A.2
  • 2
    • 0024380493 scopus 로고
    • Atherogenic effect of oxidized products of cholesterol
    • Hubbard RW, Ono Y, Sanchez A: Atherogenic effect of oxidized products of cholesterol. Prog. Fd. Nutr. Sci 1989, 13:17-44
    • (1989) Prog. Fd. Nutr. Sci. , vol.13 , pp. 17-44
    • Hubbard, R.W.1    Ono, Y.2    Sanchez, A.3
  • 4
    • 0342316532 scopus 로고    scopus 로고
    • Oxysterols: Modulators of cholesterol metabolism and other processes
    • Schroepfer GJ Jr: Oxysterols: modulators of cholesterol metabolism and other processes. Physiol. Rev 2000, 80:361-554
    • (2000) Physiol. Rev. , vol.80 , pp. 361-554
    • Schroepfer Jr., G.J.1
  • 6
    • 0031586358 scopus 로고    scopus 로고
    • Characteristics of 25-hydroxycholesterol-induced apoptosis in the human leukemic cell line CEM
    • AyalaTorres S, Moller PC, Johnson BH, Thompson EB: Characteristics of 25-hydroxycholesterol-induced apoptosis in the human leukemic cell line CEM. Exp. Cell Res 1997, 235:35-47
    • (1997) Exp. Cell Res. , vol.235 , pp. 35-47
    • AyalaTorres, S.1    Moller, P.C.2    Johnson, B.H.3    Thompson, E.B.4
  • 8
    • 0030600377 scopus 로고    scopus 로고
    • Oxysterols induced apoptosis in cultured smooth muscle cells through CPP32 protease activation and bcl-2 protein downregulation
    • Nishio E, Watanabe Y: Oxysterols induced apoptosis in cultured smooth muscle cells through CPP32 protease activation and bcl-2 protein downregulation. Biochem. Biophys. Res. Commun 1996, 226:928-934
    • (1996) Biochem. Biophys. Res. Commun. , vol.226 , pp. 928-934
    • Nishio, E.1    Watanabe, Y.2
  • 9
    • 0030995802 scopus 로고    scopus 로고
    • Programmed cell death in neurons: Focus on the pathway of nerve growth factor deprivation-induced death of sympathetic neurons
    • Deshmukh M, Johnson EM: Programmed cell death in neurons: Focus on the pathway of nerve growth factor deprivation-induced death of sympathetic neurons. Mol. Pharmacol 1997, 51:897-906
    • (1997) Mol. Pharmacol. , vol.51 , pp. 897-906
    • Deshmukh, M.1    Johnson, E.M.2
  • 10
    • 0026058318 scopus 로고
    • Cell death during development of the nervous system
    • Oppenheim RW: Cell death during development of the nervous system. Annu. Rev. Neurosci 1991, 14:453-501
    • (1991) Annu. Rev. Neurosci. , vol.14 , pp. 453-501
    • Oppenheim, R.W.1
  • 11
    • 0027373764 scopus 로고
    • Programmed cell death and the control of cell survival - Lessons from the nervous system
    • Raff MC, Barres BA, Burne JF, Coles HS, Ishizaki Y, Jacobson MD: Programmed cell death and the control of cell survival - Lessons from the nervous system. Science 1993, 262:695-700
    • (1993) Science , vol.262 , pp. 695-700
    • Raff, M.C.1    Barres, B.A.2    Burne, J.F.3    Coles, H.S.4    Ishizaki, Y.5    Jacobson, M.D.6
  • 12
    • 0031600501 scopus 로고    scopus 로고
    • Growth factors and mitogen-activated protein kinases
    • Force T, Bonventre JV: Growth factors and mitogen-activated protein kinases. Hypertension 1998, 31:152-161
    • (1998) Hypertension , vol.31 , pp. 152-161
    • Force, T.1    Bonventre, J.V.2
  • 13
    • 0031825424 scopus 로고    scopus 로고
    • Mitogen-activated protein kinase cascades as regulators of stress responses
    • Karin M: Mitogen-activated protein kinase cascades as regulators of stress responses. Ann. N. Y. Acad. Sci 1998, 851:139-146
    • (1998) Ann. N. Y. Acad. Sci. , vol.851 , pp. 139-146
    • Karin, M.1
  • 14
    • 0029011218 scopus 로고
    • The MAPK signaling cascade
    • Seger R, Krebs EG: The MAPK signaling cascade. FASEB J 1995, 9:726-735
    • (1995) FASEB J. , vol.9 , pp. 726-735
    • Seger, R.1    Krebs, E.G.2
  • 16
    • 0034627879 scopus 로고    scopus 로고
    • Microtubule inhibitors elicit differential effects on MAP kinase (JNK, ERK, and p38) signaling pathways in human KB-3 carcinoma cells
    • Stone AA, Chambers TC: Microtubule inhibitors elicit differential effects on MAP kinase (JNK, ERK, and p38) signaling pathways in human KB-3 carcinoma cells. Exp. Cell Res 2000, 254:110-119
    • (2000) Exp. Cell Res. , vol.254 , pp. 110-119
    • Stone, A.A.1    Chambers, T.C.2
  • 17
    • 0031015765 scopus 로고    scopus 로고
    • Oxidized LDL stimulates mitogen-activated protein kinases in smooth muscle cells and macrophages
    • Kusuhara M, Chait A, Cader A, Berk BC: Oxidized LDL stimulates mitogen-activated protein kinases in smooth muscle cells and macrophages. Arterioscler. Thromb. Vasc. Biol 1997, 17:141-148
    • (1997) Arterioscler. Thromb. Vasc. Biol. , vol.17 , pp. 141-148
    • Kusuhara, M.1    Chait, A.2    Cader, A.3    Berk, B.C.4
  • 18
    • 0033888287 scopus 로고    scopus 로고
    • Increased expression and activation of stress-activated protein kinases/c-Jun NH(2)-terminal protein kinases in atherosclerotic lesions coincide with p53
    • Metzler B, Hu Y, Dietrich H, Xu Q: Increased expression and activation of stress-activated protein kinases/c-Jun NH(2)-terminal protein kinases in atherosclerotic lesions coincide with p53. Am. J. Pathol 2000, 156:1875-1886
    • (2000) Am. J. Pathol. , vol.156 , pp. 1875-1886
    • Metzler, B.1    Hu, Y.2    Dietrich, H.3    Xu, Q.4
  • 19
    • 0034713444 scopus 로고    scopus 로고
    • Roles of PPARs in health and disease
    • Kersten S, Desvergne B, Wahli W: Roles of PPARs in health and disease. Nature 2000, 405:421-424
    • (2000) Nature , vol.405 , pp. 421-424
    • Kersten, S.1    Desvergne, B.2    Wahli, W.3
  • 20
    • 0034034671 scopus 로고    scopus 로고
    • Central role of peroxisome proliferator-activated receptors in the actions of peroxisome proliferators
    • Corton JC, Anderson SP, Stauber A: Central role of peroxisome proliferator-activated receptors in the actions of peroxisome proliferators. Annu. Rev. Pharmacol. Toxicol 2000, 40:491-518
    • (2000) Annu. Rev. Pharmacol. Toxicol. , vol.40 , pp. 491-518
    • Corton, J.C.1    Anderson, S.P.2    Stauber, A.3
  • 21
    • 0034057069 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptors in the cardiovascular system
    • Bishop-Bailey D: Peroxisome proliferator-activated receptors in the cardiovascular system. Br. J. Pharmacol 2000, 129:823-834
    • (2000) Br. J. Pharmacol. , vol.129 , pp. 823-834
    • Bishop-Bailey, D.1
  • 22
    • 0032560545 scopus 로고    scopus 로고
    • Expression of the peroxisome proliferator-activated receptor gamma (PPARgamma) in human atherosclerosis and regulation in macrophages by colony stimulating factors and oxidized low density lipoprotein
    • Ricote M, Huang J, Fajas L, Li A, Welch J, Najib J, Witztum JL, Auwerx J, Palinski W, Glass CK: Expression of the peroxisome proliferator-activated receptor gamma (PPARgamma) in human atherosclerosis and regulation in macrophages by colony stimulating factors and oxidized low density lipoprotein. Proc. Natl. Acad. Sci. USA 1998, 95:7614-7619
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 7614-7619
    • Ricote, M.1    Huang, J.2    Fajas, L.3    Li, A.4    Welch, J.5    Najib, J.6    Witztum, J.L.7    Auwerx, J.8    Palinski, W.9    Glass, C.K.10
  • 23
    • 0032540325 scopus 로고    scopus 로고
    • Oxidized LDL regulates macrophage gene expression through ligand activation of PPARgamma
    • Nagy L, Tontonoz P, Alvarez JG, Chen H, Evans RM: Oxidized LDL regulates macrophage gene expression through ligand activation of PPARgamma. Cell 1998, 93:229-240
    • (1998) Cell , vol.93 , pp. 229-240
    • Nagy, L.1    Tontonoz, P.2    Alvarez, J.G.3    Chen, H.4    Evans, R.M.5
  • 24
    • 0031888958 scopus 로고    scopus 로고
    • PPAR-gamma agonists inhibit production of monocyte inflammatory cytokines
    • Jiang C, Ting AT, Seed B: PPAR-gamma agonists inhibit production of monocyte inflammatory cytokines. Nature 1998, 391:82-86
    • (1998) Nature , vol.391 , pp. 82-86
    • Jiang, C.1    Ting, A.T.2    Seed, B.3
  • 25
    • 0031886864 scopus 로고    scopus 로고
    • The peroxisome proliferator-activated receptor-gamma is a negative regulator of macrophage activation
    • Ricote M, Li AC, Willson TM, Kelly CJ, Glass CK: The peroxisome proliferator-activated receptor-gamma is a negative regulator of macrophage activation. Nature 1998, 391:79-82
    • (1998) Nature , vol.391 , pp. 79-82
    • Ricote, M.1    Li, A.C.2    Willson, T.M.3    Kelly, C.J.4    Glass, C.K.5
  • 26
    • 0033864582 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor gamma ligands inhibit development of atherosclerosis in LDL receptor-deficient mice
    • Li AC, Brown KK, Silvestre MJ, Willson TM, Palinski W, Glass CK: Peroxisome proliferator-activated receptor gamma ligands inhibit development of atherosclerosis in LDL receptor-deficient mice. J. Clin. Invest 2000, 106:523-531
    • (2000) J. Clin. Invest. , vol.106 , pp. 523-531
    • Li, A.C.1    Brown, K.K.2    Silvestre, M.J.3    Willson, T.M.4    Palinski, W.5    Glass, C.K.6
  • 27
    • 0031013395 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptors alpha and gamma are activated by indomethacin and other non-steroidal antiinflammatory drugs
    • Lehmann JM, Lenhard JM, Oliver BB, Ringold GM, Kliewer SA: Peroxisome proliferator-activated receptors alpha and gamma are activated by indomethacin and other non-steroidal antiinflammatory drugs. J. Biol. Chem 1997, 272:3406-3410
    • (1997) J. Biol. Chem. , vol.272 , pp. 3406-3410
    • Lehmann, J.M.1    Lenhard, J.M.2    Oliver, B.B.3    Ringold, G.M.4    Kliewer, S.A.5
  • 28
    • 0030791051 scopus 로고    scopus 로고
    • Oxidation of cholesterol in synaptosomes and mitochondria isolated from rat brains
    • Vatassery GT, Quach HT, Smith WE, Ungar F: Oxidation of cholesterol in synaptosomes and mitochondria isolated from rat brains. Lipids 1997, 32:879-886
    • (1997) Lipids , vol.32 , pp. 879-886
    • Vatassery, G.T.1    Quach, H.T.2    Smith, W.E.3    Ungar, F.4
  • 29
    • 0030879515 scopus 로고    scopus 로고
    • 25-Hydroxycholesterol causes death but does not prevent NGF-induced neurite outgrowth in PC12 cells
    • Chang JY, Liu LZ: 25-Hydroxycholesterol causes death but does not prevent NGF-induced neurite outgrowth in PC12 cells. Neurochem. Int 1997, 31:517-523
    • (1997) Neurochem. Int. , vol.31 , pp. 517-523
    • Chang, J.Y.1    Liu, L.Z.2
  • 30
    • 0031894742 scopus 로고    scopus 로고
    • Neurotoxicity of 25-OH-cholesterol on NGF-differentiated PC12 cells
    • Chang JY, Phelan KD, Liu LZ: Neurotoxicity of 25-OH-cholesterol on NGF-differentiated PC12 cells. Neurochem. Res 1998, 23:7-16
    • (1998) Neurochem. Res. , vol.23 , pp. 7-16
    • Chang, J.Y.1    Phelan, K.D.2    Liu, L.Z.3
  • 31
    • 0032053144 scopus 로고    scopus 로고
    • Neurotoxicity of 25-OH-cholesterol on sympathetic neurons
    • Chang JY, Phelan KD, Chavis JA: Neurotoxicity of 25-OH-cholesterol on sympathetic neurons. Brain Res. Bull 1998, 45:615-622
    • (1998) Brain Res. Bull. , vol.45 , pp. 615-622
    • Chang, J.Y.1    Phelan, K.D.2    Chavis, J.A.3
  • 32
    • 0031975868 scopus 로고    scopus 로고
    • Toxicity of cholesterol oxides on cultured neuroretinal cells
    • Chang JY, Liu LZ: Toxicity of cholesterol oxides on cultured neuroretinal cells. Curr. Eye Res 1998, 17:95-103
    • (1998) Curr. Eye Res. , vol.17 , pp. 95-103
    • Chang, J.Y.1    Liu, L.Z.2
  • 33
    • 0032054279 scopus 로고    scopus 로고
    • Neurotoxicity of cholesterol oxides on cultured cerebellar granule cells
    • Chang JY, Liu LZ: Neurotoxicity of cholesterol oxides on cultured cerebellar granule cells. Neurochem. Int 1998, 32:317-323
    • (1998) Neurochem. Int. , vol.32 , pp. 317-323
    • Chang, J.Y.1    Liu, L.Z.2
  • 35
    • 0029434439 scopus 로고
    • The microglial cell. A historical review
    • Barron KD: The microglial cell. A historical review. J. Neurol. Sci 1995, 134:57-68
    • (1995) J. Neurol. Sci. , vol.134 , pp. 57-68
    • Barron, K.D.1
  • 36
    • 0033527569 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor alpha negatively regulates the vascular inflammatory gene response by negative crosstalk with transcription factors NF-kappaB and AP-1
    • Delerive P, De Bosscher K, Besnard S, Vanden Berghe W, Peters JM, Gonzalez FJ, Fruchart JC, Tedgui A, Haegeman G, Staels B: Peroxisome proliferator-activated receptor alpha negatively regulates the vascular inflammatory gene response by negative crosstalk with transcription factors NF-kappaB and AP-1. J. Biol. Chem 1999, 274:32048-32054
    • (1999) J. Biol. Chem. , vol.274 , pp. 32048-32054
    • Delerive, P.1    De Bosscher, K.2    Besnard, S.3    Vanden Berghe, W.4    Peters, J.M.5    Gonzalez, F.J.6    Fruchart, J.C.7    Tedgui, A.8    Haegeman, G.9    Staels, B.10
  • 37
    • 0033520304 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor activators inhibit thrombin-induced endothelin-1 production in human vascular endothelial cells by inhibiting the activator protein-1 signaling pathway
    • Delerive P, Martin-Nizard F, Chinetti G, Trottein F, Fruchart JC, Najib J, Duriez P, Staels B: Peroxisome proliferator-activated receptor activators inhibit thrombin-induced endothelin-1 production in human vascular endothelial cells by inhibiting the activator protein-1 signaling pathway. Circ. Res 1999, 85:394-402
    • (1999) Circ. Res. , vol.85 , pp. 394-402
    • Delerive, P.1    Martin-Nizard, F.2    Chinetti, G.3    Trottein, F.4    Fruchart, J.C.5    Najib, J.6    Duriez, P.7    Staels, B.8
  • 38
    • 0022974733 scopus 로고
    • Occurrence of lipid oxidation products in foods
    • Addis PB: Occurrence of lipid oxidation products in foods. Fd. Chem. Toxic 1986, 24:1021-1030
    • (1986) Fd. Chem. Toxic. , vol.24 , pp. 1021-1030
    • Addis, P.B.1
  • 39
    • 0031849652 scopus 로고    scopus 로고
    • Cholesterol oxidation in meat from chickens fed alpha-tocopherol- and betacarotene-supplemented diets with different unsaturation grades
    • Maraschiello C, Esteve E, Garcia Regueiro JA: Cholesterol oxidation in meat from chickens fed alpha-tocopherol- and betacarotene-supplemented diets with different unsaturation grades. Lipids 1998, 33:705-713
    • (1998) Lipids , vol.33 , pp. 705-713
    • Maraschiello, C.1    Esteve, E.2    Garcia Regueiro, J.A.3
  • 40
    • 0019850959 scopus 로고
    • Sterol metabolism-XLVII. Oxidized cholesterol esters in human tissues
    • Smith LL, Teng JI, Lin YY, Seitz PK: Sterol metabolism-XLVII. Oxidized cholesterol esters in human tissues. J. Steroid Biochem 1981, 14:889-900
    • (1981) J. Steroid Biochem. , vol.14 , pp. 889-900
    • Smith, L.L.1    Teng, J.I.2    Lin, Y.Y.3    Seitz, P.K.4
  • 41
    • 0030972394 scopus 로고    scopus 로고
    • The effect of oxidizing cholesterol on gastrointestinal absorption, plasma clearance, tissue distribution, and processing by endothelial cells
    • Krut LH, Yang JW, Schonfeld G, Ostlund RE: The effect of oxidizing cholesterol on gastrointestinal absorption, plasma clearance, tissue distribution, and processing by endothelial cells. Arterioscler. Thromb. Vasc. Biol 1997, 17:778-785
    • (1997) Arterioscler Thromb. Vasc. Biol. , vol.17 , pp. 778-785
    • Krut, L.H.1    Yang, J.W.2    Schonfeld, G.3    Ostlund, R.E.4
  • 42
    • 0028999147 scopus 로고
    • Movement of 25-hydroxycholesterol from the plasma membrane to the rough endoplastic reticulum in cultured hepatoma cells
    • Lange Y, Ye J, Strebel F: Movement of 25-hydroxycholesterol from the plasma membrane to the rough endoplastic reticulum in cultured hepatoma cells. J. Lipid Res 1995, 36:1092-1097
    • (1995) J. Lipid Res. , vol.36 , pp. 1092-1097
    • Lange, Y.1    Ye, J.2    Strebel, F.3
  • 43
    • 0025776831 scopus 로고
    • Cholesterol feeding increases plasma and aortic tissue cholesterol oxides levels in parallel: Further evidence for the role of cholesterol oxidation in atherosclerosis
    • Hodis HN, Crawford DW, Sevanian A: Cholesterol feeding increases plasma and aortic tissue cholesterol oxides levels in parallel: Further evidence for the role of cholesterol oxidation in atherosclerosis. Atherosclerosis 1991, 89:117-126
    • (1991) Atherosclerosis , vol.89 , pp. 117-126
    • Hodis, H.N.1    Crawford, D.W.2    Sevanian, A.3
  • 47
    • 0016206178 scopus 로고
    • Suppression of 3-hydroxy-3-methylglutaryl coenzyme A reductase activity and inhibition of growth of human fibroblasts by 7-ketocholesterol
    • Brown MS, Goldstein JL: Suppression of 3-hydroxy-3-methylglutaryl coenzyme A reductase activity and inhibition of growth of human fibroblasts by 7-ketocholesterol. J. Biol. Chem 1974, 249:7306-7314
    • (1974) J. Biol. Chem. , vol.249 , pp. 7306-7314
    • Brown, M.S.1    Goldstein, J.L.2
  • 48
    • 0021747172 scopus 로고
    • Correlation between oxysterol binding to a cytosolic binding protein and potency in the repression of hydroxymethylglutaryl coenzyme A reductase
    • Taylor FR, Saucier SE, Shown EP, Parish EJ, Kandutsch AA: Correlation between oxysterol binding to a cytosolic binding protein and potency in the repression of hydroxymethylglutaryl coenzyme A reductase. J. Biol. Chem 1984, 259:12382-12387
    • (1984) J. Biol. Chem. , vol.259 , pp. 12382-12387
    • Taylor, F.R.1    Saucier, S.E.2    Shown, E.P.3    Parish, E.J.4    Kandutsch, A.A.5
  • 49
    • 0026640992 scopus 로고
    • Correlation among oxysterol potencies in the regulation of the degradation of 3-hydroxy-3-methylglutaryl CoA reductase, the depression of 3-hydroxy-3-methylglutaryl CoA synthase and affinities for the oxysterol receptor
    • Taylor F: Correlation among oxysterol potencies in the regulation of the degradation of 3-hydroxy-3-methylglutaryl CoA reductase, the depression of 3-hydroxy-3-methylglutaryl CoA synthase and affinities for the oxysterol receptor. Biochem. Biophys. Res. Comm 1992, 186:182-189
    • (1992) Biochem. Biophys. Res. Comm. , vol.186 , pp. 182-189
    • Taylor, F.1
  • 50
    • 0342445430 scopus 로고    scopus 로고
    • Isolation of a somatic cell mutant resistant to the induction of apoptosis by oxidized low density lipoprotein
    • Rusinol AE, Yang L, Thewke D, Panini SR, Kramer MF, Sinensky MS: Isolation of a somatic cell mutant resistant to the induction of apoptosis by oxidized low density lipoprotein. J. Biol. Chem 2000, 275:7296-7303
    • (2000) J. Biol. Chem. , vol.275 , pp. 7296-7303
    • Rusinol, A.E.1    Yang, L.2    Thewke, D.3    Panini, S.R.4    Kramer, M.F.5    Sinensky, M.S.6
  • 51
    • 0033022015 scopus 로고    scopus 로고
    • Oxysterols and apoptosis: Evidence for gene regulation outside the cholesterol pathway
    • Thompson EB, Ayala-Torres S: Oxysterols and apoptosis: evidence for gene regulation outside the cholesterol pathway. Crit. Rev. Biochem. Mol. Biol 1999, 34:25-32
    • (1999) Crit. Rev. Biochem. Mol. Biol. , vol.34 , pp. 25-32
    • Thompson, E.B.1    Ayala-Torres, S.2
  • 52
    • 0032935664 scopus 로고    scopus 로고
    • Mitogen-activated protein kinases: Specific messages from ubiquitous messengers
    • Schaeffer HJ, Weber MJ: Mitogen-activated protein kinases: specific messages from ubiquitous messengers. Mol. Cell. Biol 1999, 19:2435-2444
    • (1999) Mol. Cell. Biol. , vol.19 , pp. 2435-2444
    • Schaeffer, H.J.1    Weber, M.J.2
  • 56
    • 0033944415 scopus 로고    scopus 로고
    • Role of the peroxisome proliferator-activated receptor-gamma (PPAR-gamma) and its natural ligand 15-deoxy-Delta12, 14-prostaglandin J2 in the regulation of microglial functions
    • Bernardo A, Levi G, Minghetti L: Role of the peroxisome proliferator-activated receptor-gamma (PPAR-gamma) and its natural ligand 15-deoxy-Delta12, 14-prostaglandin J2 in the regulation of microglial functions. Eur. J. Neurosci 2000, 12:2215-2223
    • (2000) Eur. J. Neurosci. , vol.12 , pp. 2215-2223
    • Bernardo, A.1    Levi, G.2    Minghetti, L.3
  • 57
    • 0034625485 scopus 로고    scopus 로고
    • Cyclopentenone prostaglandin 15-deoxy-Delta(12,14)-prostaglandin J(2) acts as a general inhibitor of inflammatory responses in activated BV-2 microglial cells
    • Koppal T, Petrova TV, Van Eldik LJ: Cyclopentenone prostaglandin 15-deoxy-Delta(12,14)-prostaglandin J(2) acts as a general inhibitor of inflammatory responses in activated BV-2 microglial cells. Brain Res 2000, 867:115-121
    • (2000) Brain Res. , vol.867 , pp. 115-121
    • Koppal, T.1    Petrova, T.V.2    Van Eldik, L.J.3
  • 58
    • 0033551134 scopus 로고    scopus 로고
    • Cyclopentenone prostaglandins suppress activation of microglia: Down-regulation of inducible nitric-oxide synthase by 15-deoxy-Delta12,14-prostaglandin J2
    • Petrova TV, Akama KT, Van Eldik LJ: Cyclopentenone prostaglandins suppress activation of microglia: down-regulation of inducible nitric-oxide synthase by 15-deoxy-Delta12,14-prostaglandin J2. Proc. Natl. Acad. Sci. USA 1999, 96:4668-4673
    • (1999) Proc. Natl. Acad. Sci. USA , vol.96 , pp. 4668-4673
    • Petrova, T.V.1    Akama, K.T.2    Van Eldik, L.J.3
  • 59
    • 0033378706 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor gamma agonists protect cerebellar granule cells from cytokine-induced apoptotic cell death by inhibition of inducible nitric oxide synthase
    • Heneka MT, Feinstein DL, Galea E, Gleichmann M, Wullner U, Klockgether T: Peroxisome proliferator-activated receptor gamma agonists protect cerebellar granule cells from cytokine-induced apoptotic cell death by inhibition of inducible nitric oxide synthase. J. Neuroimmunol 1999, 100:156-168
    • (1999) J. Neuroimmunol. , vol.100 , pp. 156-168
    • Heneka, M.T.1    Feinstein, D.L.2    Galea, E.3    Gleichmann, M.4    Wullner, U.5    Klockgether, T.6
  • 60
    • 0034651101 scopus 로고    scopus 로고
    • Inflammatory mechanisms in Alzheimer's disease: Inhibition of beta-amyloid-stimulated proinflammatory responses and neurotoxicity by PPARgamma agonists
    • Combs CK, Johnson DE, Karlo JC, Cannady SB, Landreth GE: Inflammatory mechanisms in Alzheimer's disease: inhibition of beta-amyloid-stimulated proinflammatory responses and neurotoxicity by PPARgamma agonists. J. Neurosci 2000, 20:558-567
    • (2000) J. Neurosci. , vol.20 , pp. 558-567
    • Combs, C.K.1    Johnson, D.E.2    Karlo, J.C.3    Cannady, S.B.4    Landreth, G.E.5
  • 61
    • 0031819433 scopus 로고    scopus 로고
    • Evidence for the suppression of apoptosis by the peroxisome proliferator activated receptor alpha (PPAR alpha)
    • Roberts RA, James NH, Woodyatt NJ, Macdonald N, Tugwood JD: Evidence for the suppression of apoptosis by the peroxisome proliferator activated receptor alpha (PPAR alpha). Carcinogenesis 1998, 19:43-48
    • (1998) Carcinogenesis , vol.19 , pp. 43-48
    • Roberts, R.A.1    James, N.H.2    Woodyatt, N.J.3    Macdonald, N.4    Tugwood, J.D.5
  • 63
    • 0034048666 scopus 로고    scopus 로고
    • Interferon-gamma induces apoptosis and augments the expression of Fas and Fas ligand by microglia in vitro
    • Badie B, Schartner J, Vorpahl J, Preston K: Interferon-gamma induces apoptosis and augments the expression of Fas and Fas ligand by microglia in vitro. Exp. Neurol 2000, 162:290-296
    • (2000) Exp. Neurol. , vol.162 , pp. 290-296
    • Badie, B.1    Schartner, J.2    Vorpahl, J.3    Preston, K.4
  • 64
    • 0030610645 scopus 로고    scopus 로고
    • Microglial activation by Alzheimer amyloid precursor protein and modulation by apolipoprotein E
    • Barger SW, Harmon AD: Microglial activation by Alzheimer amyloid precursor protein and modulation by apolipoprotein E. Nature 1997, 388:878-881
    • (1997) Nature , vol.388 , pp. 878-881
    • Barger, S.W.1    Harmon, A.D.2
  • 66
    • 0023804295 scopus 로고
    • N-Methyl-D-Aspartate promotes the survival of cerebellar granule cells in culture
    • Balazs R, Jorgensen OS, Hack N: N-Methyl-D-Aspartate promotes the survival of cerebellar granule cells in culture. Neuroscience 1988, 27:437-451
    • (1988) Neuroscience , vol.27 , pp. 437-451
    • Balazs, R.1    Jorgensen, O.S.2    Hack, N.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.