Activation of the orphan nuclear receptor steroidogenic factor 1 by oxysterols

Proceedings of the National Academy of Sciences of the United States of America

Volumn 94, Issue 10, 1997, Pages 4895-4900

  Lala, Deepak S ^a   Syka, Peter M ^a   Lazarchik, Steven B ^a   Mangelsdorf, David J ^b   Parker, Keith L ^c   Heyman, Richard A ^a  

^a LIGAND PHARMACEUTICALS INC   (United States)

^b UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^c DUKE UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL NUCLEUS RECEPTOR; CHOLESTEROL DERIVATIVE; DEXAMETHASONE; ESTRADIOL; HYDROXYSTEROL; PRASTERONE; PREGNENOLONE; PROGESTERONE; STEROIDOGENIC FACTOR 1; TESTOSTERONE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CHOLESTEROL SYNTHESIS; HORMONE RECEPTOR INTERACTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; RECEPTOR UPREGULATION; STEROIDOGENESIS; TRANSCRIPTION REGULATION;

AMINO ACID SEQUENCE; ANIMALS; BINDING SITES; CELL LINE; CERCOPITHECUS AETHIOPS; DNA-BINDING PROTEINS; FUSHI TARAZU TRANSCRIPTION FACTORS; GREEN FLUORESCENT PROTEINS; HOMEODOMAIN PROTEINS; HUMANS; HYDROXYCHOLESTEROLS; KINETICS; LUMINESCENT PROTEINS; MOLECULAR SEQUENCE DATA; RECEPTORS, CYTOPLASMIC AND NUCLEAR; RECEPTORS, THYROID HORMONE; RECOMBINANT FUSION PROTEINS; SEQUENCE HOMOLOGY, AMINO ACID; TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC; TRANSFECTION;

EID: 0031000199     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.94.10.4895     Document Type: Article

References (30)

1. Lala, D. S., Rice, D. A. & Parker, K. L. (1992) Mol. Endocrinol. 6, 1249-1258.
2. Luo, X., Ikeda, Y. & Parker, K. L. (1994) Cell 77, 481-490.
3. Lala, D. S., Ikeda, Y., Luo, X., Baity, L. A., Meade, J. C. & Parker, K. L. (1995) Steroids 60, 10-14.
4. Ikeda, Y., Lala, D. S., Luo, X., Kim, E., Moisan, M.-P. & Parker, K. L. (1993) Mol. Endocrinol. 7, 852-860.
5. Lin, D., Sugawara, T., Strauss, J. F., Clark, B. J., Stocco, D. M., Saenger, P., Rogol, A. & Miller, W. (1995) Science 267, 1828-1831.
6. Sugawara, T., Holt, J. A., Kiriakidou, M. & Strauss, J. F. (1996) Biochemistry 35, 9052-9059.
7. Ingraham, H. A., Lala, D. S., Ikeda, Y., Luo, X., Shen, W.-H., Nachtigal, M. W., Abbud, R., Nilson, J. H. & Parker, K. L. (1994) Genes Dev. 8, 2302-2312.
8. Russell, D. W. (1992) Cardiovasc. Drugs Ther. 6, 103-110.
9. Kandutsch, A. A., Chen, H. W. & Heiniger, H. J. (1978) Science 201, 498-501.
10. Andersson, S., Davis, D. L., Dahlbäck, H., Jörnvall, H. & Russell, D. W. (1989) J. Biol. Chem. 264, 8222-8229.
11. Rennert, H., Fischer, R. T., Alvarez, J. G., Trzaskos, J. M. & Strauss, J. F. (1990) Endocrinol. 127, 738-746.
12. Payne, D. W., Shackleton, C., Toms, H., Ben-Shlomo, I., Kol, S., deMoura, M., Strauss, J. F. & Adashi, E. Y. (1995) J. Biol. Chem. 270, 18888-18896.
13. Saucier, S. E., Kandutsch, A. A., Taylor, F. R., Spencer, T. A., Phirwa, S. & Gayen, A. K. (1985) J. Biol. Chem. 260, 14571-14579.
14. Breuer, O. & Björkhem, I. (1995) J. Biol. Chem. 270, 20278-20284.
15. Saucier, S. E., Kandutsch, A. A., Gayen, A. K., Swahn, D. K. & Spencer, T. A. (1989) J. Biol. Chem. 264, 6863-6869.
16. Alsema, G. J., Degenhart, H. J. & Hoogerbrugge, J. (1980) J. Steroid Biochem. 13, 539-543.
17. Javitt, N. B., Kok, E., Burstein, S, Betram, C. & Kutshcer, J. (1981) J. Biol. Chem. 256, 12644-12646.
18. Axelson, M. & Larsson, O. (1995) J. Biol. Chem. 270, 15102-15110.
19. Cali, J. J. & Russell, D. W. (1991) J. Biol. Chem. 266, 7774-7778.
20. Jelinek, D. F., Andersson, S., Slaughter, C. A. & Russell, D. W. (1990) J. Biol. Chem. 265, 8190-8197.
21. Dixon, R., Furutachi, T. & Lieberman, S. (1970) Biochem. Biophys. Res. Commun. 40, 161-165.
22. Dhar, A. K., Teng, J. I. & Smith, L. L. (1973) J. Neurochem. 21, 51-60.
23. Danielian, P. S., White, R., Hoare, S. A., Fawell, S. E. & Parker, M. G. (1993) Mol. Endocrinol. 7, 232-240.
24. Durand, B., Saunders, M., Gaudon, C., Roy, B., Losson, R. & Chambon, P. (1994) EMBO J. 13, 5370-5382.
25. Janowski, B. A., Willy, P. J., Devi, T. R., Falck, J. R. & Mangelsdorf, D. J. (1996) Nature (London) 383, 728-731.
26. Willy, P. J., Umesono, K., Ong, E. S., Evans, R. M., Heyman, R. A. & Mangelsdorf, D. J. (1995) Genes Dev. 9, 1033-1045.
27. Wang, X., Sato, R., Brown, M. S., Hua, X. & Goldstein, J. L. (1994) Cell 77, 53-62.
28. Nomura, M., Nawata, H. & Morohashi, K.-i. (1996) J. Biol. Chem. 271, 8243-8249.
29. Sugawara, T., Lin, D., Holt, J. A., Martin, K. O., Javitt, N. B., Miller, W. L. & Strauss, J. F. (1995) Biochemistry 34, 12506-12512.
30. Forman, B. M., Goode, E. Chen, J., Oro, A. E., Bradley, D. J., Perlmann, T., Noonan, D. J., Burka, L. T., McMorris, T., Lamph, W. W., Evans, R. M. & Weinberger, C. (1995) Cell 81, 687-693.