Cyclopentenone prostaglandin 15-deoxy-Δ12,14-prostaglandin J2 acts as a general inhibitor of inflammatory responses in activated BV-2 microglial cells

Brain Research

Volumn 867, Issue 1-2, 2000, Pages 115-121

  Koppal, Tanuja ^a   Petrova, Tatiana V ^a,b   Van Eldik, Linda J ^a  

^a NORTHWESTERN UNIVERSITY   (United States)

^b UNIVERSITY OF HELSINKI   (Finland)

Author keywords

Glial activation; Inflammatory cytokine; Lipopolysaccharide; Nitric oxide synthase; Oxidative stress; Prostaglandin

Indexed keywords

15 DEOXY DELTA 12,14 PROSTAGLANDIN J2; CYCLOOXYGENASE 2 INHIBITOR; DELTA12 PROSTAGLANDIN J2; GLUTATHIONE; HEME OXYGENASE; INTERLEUKIN 1BETA; LIPOPOLYSACCHARIDE; PROSTAGLANDIN DERIVATIVE; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; MICROGLIA; MOUSE; NONHUMAN; PRIORITY JOURNAL;

ANIMALS; CELL LINE; CYCLOOXYGENASE 2; GLUTATHIONE; HEME OXYGENASE (DECYCLIZING); HEME OXYGENASE-1; INTERLEUKIN-1; ISOENZYMES; LIPOPOLYSACCHARIDES; MEMBRANE PROTEINS; METALLOPORPHYRINS; MICE; MICROGLIA; NEURITIS; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE TYPE II; OXIDATIVE STRESS; PROSTAGLANDIN D2; PROSTAGLANDIN-ENDOPEROXIDE SYNTHASES; TUMOR NECROSIS FACTOR-ALPHA;

EID: 0034625485     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-8993(00)02270-8     Document Type: Article

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