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Volumn 309, Issue 2, 2005, Pages 410-418

Dual-specificity phosphatase DUSP1 protects overactivation of hypoxia-inducible factor 1 through inactivating ERK MAPK

Author keywords

HIF 1; Hypoxia; MAPK; MKP 1; Phosphorylation; Transactivation

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; HYPOXIA INDUCIBLE FACTOR 1; MITOGEN ACTIVATED PROTEIN KINASE 1; PROTEIN P300;

EID: 24944488029     PISSN: 00144827     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.yexcr.2005.06.022     Document Type: Article
Times cited : (49)

References (58)
  • 1
    • 0035500503 scopus 로고    scopus 로고
    • Hypoxia: The tumor's gateway to progression along the angiogenic pathway
    • C. Brahimi-Horn, E. Berra, and J. Pouyssegur Hypoxia: the tumor's gateway to progression along the angiogenic pathway Trends Cell Biol. 11 2001 S32 S36
    • (2001) Trends Cell Biol. , vol.11
    • Brahimi-Horn, C.1    Berra, E.2    Pouyssegur, J.3
  • 2
    • 0036359548 scopus 로고    scopus 로고
    • Hypoxia-A key regulatory factor in tumour growth
    • A.L. Harris Hypoxia-A key regulatory factor in tumour growth Nat. Rev., Cancer 2 2002 38 47
    • (2002) Nat. Rev., Cancer , vol.2 , pp. 38-47
    • Harris, A.L.1
  • 3
    • 0036216692 scopus 로고    scopus 로고
    • HIF-1 and tumor progression: Pathophysiology and therapeutics
    • G.L. Semenza HIF-1 and tumor progression: pathophysiology and therapeutics Trends Mol. Med. 8 2002 S62 S67
    • (2002) Trends Mol. Med. , vol.8
    • Semenza, G.L.1
  • 6
    • 0035903468 scopus 로고    scopus 로고
    • Independent function of two destruction domains in hypoxia-inducible factor-alpha chains activated by prolyl hydroxylation
    • N. Masson, C. Willam, P.H. Maxwell, C.W. Pugh, and P.J. Ratcliffe Independent function of two destruction domains in hypoxia-inducible factor-alpha chains activated by prolyl hydroxylation EMBO J. 20 2001 5197 5206
    • (2001) EMBO J. , vol.20 , pp. 5197-5206
    • Masson, N.1    Willam, C.2    Maxwell, P.H.3    Pugh, C.W.4    Ratcliffe, P.J.5
  • 7
    • 0036469146 scopus 로고    scopus 로고
    • Transcription. Oxygen sensing gets a second wind
    • R.K. Bruick, and S.L. McKnight Transcription. Oxygen sensing gets a second wind Science 295 2002 807 808
    • (2002) Science , vol.295 , pp. 807-808
    • Bruick, R.K.1    McKnight, S.L.2
  • 8
    • 0041465022 scopus 로고    scopus 로고
    • HIF prolyl-hydroxylase 2 is the key oxygen sensor setting low steady-state levels of HIF-1alpha in normoxia
    • E. Berra, E. Benizri, A. Ginouves, V. Volmat, D. Roux, and J. Pouyssegur HIF prolyl-hydroxylase 2 is the key oxygen sensor setting low steady-state levels of HIF-1alpha in normoxia EMBO J. 22 2003 4082 4090
    • (2003) EMBO J. , vol.22 , pp. 4082-4090
    • Berra, E.1    Benizri, E.2    Ginouves, A.3    Volmat, V.4    Roux, D.5    Pouyssegur, J.6
  • 9
    • 0037097861 scopus 로고    scopus 로고
    • FIH-1 is an asparaginyl hydroxylase enzyme that regulates the transcriptional activity of hypoxia-inducible factor
    • D. Lando, D.J. Peet, J.J. Gorman, D.A. Whelan, M.L. Whitelaw, and R.K. Bruick FIH-1 is an asparaginyl hydroxylase enzyme that regulates the transcriptional activity of hypoxia-inducible factor Genes Dev. 16 2002 1466 1471
    • (2002) Genes Dev. , vol.16 , pp. 1466-1471
    • Lando, D.1    Peet, D.J.2    Gorman, J.J.3    Whelan, D.A.4    Whitelaw, M.L.5    Bruick, R.K.6
  • 10
    • 0036469038 scopus 로고    scopus 로고
    • Asparagine hydroxylation of the HIF transactivation domain a hypoxic switch
    • D. Lando, D.J. Peet, D.A. Whelan, J.J. Gorman, and M.L. Whitelaw Asparagine hydroxylation of the HIF transactivation domain a hypoxic switch Science 295 2002 858 861
    • (2002) Science , vol.295 , pp. 858-861
    • Lando, D.1    Peet, D.J.2    Whelan, D.A.3    Gorman, J.J.4    Whitelaw, M.L.5
  • 12
    • 0032725554 scopus 로고    scopus 로고
    • P42/p44 mitogen-activated protein kinases phosphorylate hypoxia-inducible factor 1alpha (HIF-1alpha) and enhance the transcriptional activity of HIF-1
    • D.E. Richard, E. Berra, E. Gothie, D. Roux, and J. Pouyssegur p42/p44 mitogen-activated protein kinases phosphorylate hypoxia-inducible factor 1alpha (HIF-1alpha) and enhance the transcriptional activity of HIF-1 J. Biol. Chem. 274 1999 32631 32637
    • (1999) J. Biol. Chem. , vol.274 , pp. 32631-32637
    • Richard, D.E.1    Berra, E.2    Gothie, E.3    Roux, D.4    Pouyssegur, J.5
  • 14
    • 0035478294 scopus 로고    scopus 로고
    • Transduction pathways involved in hypoxia-inducible factor-1 phosphorylation and activation
    • E. Minet, G. Michel, D. Mottet, M. Raes, and C. Michiels Transduction pathways involved in hypoxia-inducible factor-1 phosphorylation and activation Free Radical Biol. Med. 31 2001 847 855
    • (2001) Free Radical Biol. Med. , vol.31 , pp. 847-855
    • Minet, E.1    Michel, G.2    Mottet, D.3    Raes, M.4    Michiels, C.5
  • 15
    • 0035651033 scopus 로고    scopus 로고
    • Dissecting hypoxia-dependent and hypoxia-independent steps in the HIF-1alpha activation cascade: Implications for HIF-1alpha gene therapy
    • T. Hofer, I. Desbaillets, G. Hopfl, M. Gassmann, and R.H. Wenger Dissecting hypoxia-dependent and hypoxia-independent steps in the HIF-1alpha activation cascade: implications for HIF-1alpha gene therapy FASEB J. 15 2001 2715 2717
    • (2001) FASEB J. , vol.15 , pp. 2715-2717
    • Hofer, T.1    Desbaillets, I.2    Hopfl, G.3    Gassmann, M.4    Wenger, R.H.5
  • 16
    • 0035855668 scopus 로고    scopus 로고
    • Dephosphorylated hypoxia-inducible factor 1alpha as a mediator of p53-dependent apoptosis during hypoxia
    • H. Suzuki, A. Tomida, and T. Tsuruo Dephosphorylated hypoxia-inducible factor 1alpha as a mediator of p53-dependent apoptosis during hypoxia Oncogene 20 2001 5779 5788
    • (2001) Oncogene , vol.20 , pp. 5779-5788
    • Suzuki, H.1    Tomida, A.2    Tsuruo, T.3
  • 17
    • 0037515549 scopus 로고    scopus 로고
    • MAPK signaling up-regulates the activity of hypoxia-inducible factors by its effects on p300
    • N. Sang, D.P. Stiehl, J. Bohensky, I. Leshchinsky, V. Srinivas, and J. Caro MAPK signaling up-regulates the activity of hypoxia-inducible factors by its effects on p300 J. Biol. Chem. 278 2003 14013 14019
    • (2003) J. Biol. Chem. , vol.278 , pp. 14013-14019
    • Sang, N.1    Stiehl, D.P.2    Bohensky, J.3    Leshchinsky, I.4    Srinivas, V.5    Caro, J.6
  • 18
    • 0034096201 scopus 로고    scopus 로고
    • Protein phosphatases and the regulation of mitogen-activated protein kinase signaling
    • S.M. Keyse Protein phosphatases and the regulation of mitogen-activated protein kinase signaling Curr. Opin. Cell Biol. 12 2000 186 192
    • (2000) Curr. Opin. Cell Biol. , vol.12 , pp. 186-192
    • Keyse, S.M.1
  • 19
    • 0035844140 scopus 로고    scopus 로고
    • Distinct binding determinants for ERK2/p38alpha and JNK map kinases mediate catalytic activation and substrate selectivity of map kinase phosphatase-1
    • D.N. Slack, O.M. Seternes, M. Gabrielsen, and S.M. Keyse Distinct binding determinants for ERK2/p38alpha and JNK map kinases mediate catalytic activation and substrate selectivity of map kinase phosphatase-1 J. Biol. Chem. 276 2001 16491 16500
    • (2001) J. Biol. Chem. , vol.276 , pp. 16491-16500
    • Slack, D.N.1    Seternes, O.M.2    Gabrielsen, M.3    Keyse, S.M.4
  • 20
    • 0037470864 scopus 로고    scopus 로고
    • LPS regulate ERK1/2-dependent signaling in cardiac fibroblasts via PKC-mediated MKP-1 induction
    • P. Stawowy, S. Goetze, C. Margeta, E. Fleck, and K. Graf LPS regulate ERK1/2-dependent signaling in cardiac fibroblasts via PKC-mediated MKP-1 induction Biochem. Biophys. Res. Commun. 303 2003 74 80
    • (2003) Biochem. Biophys. Res. Commun. , vol.303 , pp. 74-80
    • Stawowy, P.1    Goetze, S.2    Margeta, C.3    Fleck, E.4    Graf, K.5
  • 21
    • 0033617186 scopus 로고    scopus 로고
    • Mitogen-activated protein kinase phosphatase-1 (MKP-1) expression is induced by low oxygen conditions found in solid tumor microenvironments. a candidate MKP for the inactivation of hypoxia-inducible stress-activated protein kinase/c-Jun N-terminal protein kinase activity
    • K.R. Laderoute, H.L. Mendonca, J.M. Calaoagan, A.M. Knapp, A.J. Giaccia, and P.J. Stork Mitogen-activated protein kinase phosphatase-1 (MKP-1) expression is induced by low oxygen conditions found in solid tumor microenvironments. A candidate MKP for the inactivation of hypoxia-inducible stress-activated protein kinase/c-Jun N-terminal protein kinase activity J. Biol. Chem. 274 1999 12890 12897
    • (1999) J. Biol. Chem. , vol.274 , pp. 12890-12897
    • Laderoute, K.R.1    Mendonca, H.L.2    Calaoagan, J.M.3    Knapp, A.M.4    Giaccia, A.J.5    Stork, P.J.6
  • 22
    • 0035977013 scopus 로고    scopus 로고
    • Hypoxia-induced regulation of MAPK phosphatase-1 as identified by subtractive suppression hybridization and cDNA microarray analysis
    • K.A. Seta, R. Kim, H.W. Kim, D.E. Millhorn, and D. Beitner-Johnson Hypoxia-induced regulation of MAPK phosphatase-1 as identified by subtractive suppression hybridization and cDNA microarray analysis J. Biol. Chem. 276 2001 44405 44412
    • (2001) J. Biol. Chem. , vol.276 , pp. 44405-44412
    • Seta, K.A.1    Kim, R.2    Kim, H.W.3    Millhorn, D.E.4    Beitner-Johnson, D.5
  • 23
    • 0037131170 scopus 로고    scopus 로고
    • Brain genomic response following hypoxia and re-oxygenation in the neonatal rat. Identification of genes that might contribute to hypoxia-induced ischemic tolerance
    • M. Bernaudin, Y. Tang, M. Reilly, E. Petit, and F.R. Sharp Brain genomic response following hypoxia and re-oxygenation in the neonatal rat. Identification of genes that might contribute to hypoxia-induced ischemic tolerance J. Biol. Chem. 277 2002 39728 39738
    • (2002) J. Biol. Chem. , vol.277 , pp. 39728-39738
    • Bernaudin, M.1    Tang, Y.2    Reilly, M.3    Petit, E.4    Sharp, F.R.5
  • 24
    • 10744219591 scopus 로고    scopus 로고
    • Suppression of the dual-specificity phosphatase MKP-1 enhances HIF-1 trans-activation and increases expression of EPO
    • C. Liu, Y. Shi, Z. Han, Y. Pan, N. Liu, S. Han, Y. Chen, M. Lan, T. Qiao, and D. Fan Suppression of the dual-specificity phosphatase MKP-1 enhances HIF-1 trans-activation and increases expression of EPO Biochem. Biophys. Res. Commun. 312 2003 780 786
    • (2003) Biochem. Biophys. Res. Commun. , vol.312 , pp. 780-786
    • Liu, C.1    Shi, Y.2    Han, Z.3    Pan, Y.4    Liu, N.5    Han, S.6    Chen, Y.7    Lan, M.8    Qiao, T.9    Fan, D.10
  • 25
    • 0030866226 scopus 로고    scopus 로고
    • Hypoxia induces c-fos transcription via a mitogen-activated protein kinase-dependent pathway
    • J.M. Muller, B. Krauss, C. Kaltschmidt, P.A. Baeuerle, and R.A. Rupec Hypoxia induces c-fos transcription via a mitogen-activated protein kinase-dependent pathway J. Biol. Chem. 272 1997 23435 23439
    • (1997) J. Biol. Chem. , vol.272 , pp. 23435-23439
    • Muller, J.M.1    Krauss, B.2    Kaltschmidt, C.3    Baeuerle, P.A.4    Rupec, R.A.5
  • 26
    • 0034282553 scopus 로고    scopus 로고
    • The Kaposi's sarcoma-associated herpes virus G protein-coupled receptor up-regulates vascular endothelial growth factor expression and secretion through mitogen-activated protein kinase and p38 pathways acting on hypoxia-inducible factor 1alpha
    • A. Sodhi, S. Montaner, V. Patel, M. Zohar, C. Bais, E.A. Mesri, and J.S. Gutkind The Kaposi's sarcoma-associated herpes virus G protein-coupled receptor up-regulates vascular endothelial growth factor expression and secretion through mitogen-activated protein kinase and p38 pathways acting on hypoxia-inducible factor 1alpha Cancer Res. 60 2000 4873 4880
    • (2000) Cancer Res. , vol.60 , pp. 4873-4880
    • Sodhi, A.1    Montaner, S.2    Patel, V.3    Zohar, M.4    Bais, C.5    Mesri, E.A.6    Gutkind, J.S.7
  • 27
    • 0029257329 scopus 로고
    • Inactivation of p42 MAP kinase by protein phosphatase 2A and a protein tyrosine phosphatase, but not CL100, in various cell lines
    • D.R. Alessi, N. Gomez, G. Moorhead, T. Lewis, S.M. Keyse, and P. Cohen Inactivation of p42 MAP kinase by protein phosphatase 2A and a protein tyrosine phosphatase, but not CL100, in various cell lines Curr. Biol. 5 1995 283 295
    • (1995) Curr. Biol. , vol.5 , pp. 283-295
    • Alessi, D.R.1    Gomez, N.2    Moorhead, G.3    Lewis, T.4    Keyse, S.M.5    Cohen, P.6
  • 29
    • 0026570140 scopus 로고
    • CDNA sequence of a growth factor-inducible immediate early gene and characterization of its encoded protein
    • C.H. Charles, A.S. Abler, and L.F. Lau cDNA sequence of a growth factor-inducible immediate early gene and characterization of its encoded protein Oncogene 7 1992 187 190
    • (1992) Oncogene , vol.7 , pp. 187-190
    • Charles, C.H.1    Abler, A.S.2    Lau, L.F.3
  • 30
    • 0027261369 scopus 로고
    • Structure, mapping, and expression of erp, a growth factor-inducible gene encoding a nontransmembrane protein tyrosine phosphatase, and effect of ERP on cell growth
    • T. Noguchi, R. Metz, L. Chen, M.G. Mattei, D. Carrasco, and R. Bravo Structure, mapping, and expression of erp, a growth factor-inducible gene encoding a nontransmembrane protein tyrosine phosphatase, and effect of ERP on cell growth Mol. Cell. Biol. 13 1993 5195 5205
    • (1993) Mol. Cell. Biol. , vol.13 , pp. 5195-5205
    • Noguchi, T.1    Metz, R.2    Chen, L.3    Mattei, M.G.4    Carrasco, D.5    Bravo, R.6
  • 31
    • 0026779540 scopus 로고
    • Oxidative stress and heat shock induce a human gene encoding a protein-tyrosine phosphatase
    • S.M. Keyse, and E.A. Emslie Oxidative stress and heat shock induce a human gene encoding a protein-tyrosine phosphatase Nature 359 1992 644 647
    • (1992) Nature , vol.359 , pp. 644-647
    • Keyse, S.M.1    Emslie, E.A.2
  • 32
    • 0027306121 scopus 로고
    • The human CL100 gene encodes a Tyr/Thr-protein phosphatase which potently and specifically inactivates MAP kinase and suppresses its activation by oncogenic ras in Xenopus oocyte extracts
    • D.R. Alessi, C. Smythe, and S.M. Keyse The human CL100 gene encodes a Tyr/Thr-protein phosphatase which potently and specifically inactivates MAP kinase and suppresses its activation by oncogenic ras in Xenopus oocyte extracts Oncogene 8 1993 2015 2020
    • (1993) Oncogene , vol.8 , pp. 2015-2020
    • Alessi, D.R.1    Smythe, C.2    Keyse, S.M.3
  • 34
    • 0027358722 scopus 로고
    • MKP-1 (3CH134), an immediate early gene product, is a dual specificity phosphatase that dephosphorylates MAP kinase in vivo
    • H. Sun, C.H. Charles, L.F. Lau, and N.K. Tonks MKP-1 (3CH134), an immediate early gene product, is a dual specificity phosphatase that dephosphorylates MAP kinase in vivo Cell 75 1993 487 493
    • (1993) Cell , vol.75 , pp. 487-493
    • Sun, H.1    Charles, C.H.2    Lau, L.F.3    Tonks, N.K.4
  • 35
    • 0030794511 scopus 로고    scopus 로고
    • Conditional expression of the mitogen-activated protein kinase (MAPK) phosphatase MKP-1 preferentially inhibits p38 MAPK and stress-activated protein kinase in U937 cells
    • C.C. Franklin, and A.S. Kraft Conditional expression of the mitogen-activated protein kinase (MAPK) phosphatase MKP-1 preferentially inhibits p38 MAPK and stress-activated protein kinase in U937 cells J. Biol. Chem. 272 1997 16917 16923
    • (1997) J. Biol. Chem. , vol.272 , pp. 16917-16923
    • Franklin, C.C.1    Kraft, A.S.2
  • 36
    • 1842740392 scopus 로고    scopus 로고
    • Nerve growth factor-dependent survival of CESS B cell line is mediated by increased expression and decreased degradation of MAPK phosphatase 1
    • P. Rosini, G. De Chiara, P. Bonini, M. Lucibello, M.E. Marcocci, E. Garaci, F. Cozzolino, and M. Torcia Nerve growth factor-dependent survival of CESS B cell line is mediated by increased expression and decreased degradation of MAPK phosphatase 1 J. Biol. Chem. 279 2004 14016 14023
    • (2004) J. Biol. Chem. , vol.279 , pp. 14016-14023
    • Rosini, P.1    De Chiara, G.2    Bonini, P.3    Lucibello, M.4    Marcocci, M.E.5    Garaci, E.6    Cozzolino, F.7    Torcia, M.8
  • 37
    • 1642315292 scopus 로고    scopus 로고
    • Microarray analysis reveals glucocorticoid-regulated survival genes that are associated with inhibition of apoptosis in breast epithelial cells
    • W. Wu, S. Chaudhuri, D.R. Brickley, D. Pang, T. Karrison, and S.D. Conzen Microarray analysis reveals glucocorticoid-regulated survival genes that are associated with inhibition of apoptosis in breast epithelial cells Cancer Res. 64 2004 1757 1764
    • (2004) Cancer Res. , vol.64 , pp. 1757-1764
    • Wu, W.1    Chaudhuri, S.2    Brickley, D.R.3    Pang, D.4    Karrison, T.5    Conzen, S.D.6
  • 38
    • 0035037527 scopus 로고    scopus 로고
    • Mitogen-activated protein kinase kinase inhibitor PD98059 blocks the trans-activation but not the stabilization or DNA binding ability of hypoxia-inducible factor-1alpha
    • E. Hur, K.Y. Chang, E. Lee, S.K. Lee, and H. Park Mitogen-activated protein kinase kinase inhibitor PD98059 blocks the trans-activation but not the stabilization or DNA binding ability of hypoxia-inducible factor-1alpha Mol. Pharmacol. 59 2001 1216 1224
    • (2001) Mol. Pharmacol. , vol.59 , pp. 1216-1224
    • Hur, E.1    Chang, K.Y.2    Lee, E.3    Lee, S.K.4    Park, H.5
  • 39
    • 0036139795 scopus 로고    scopus 로고
    • HIF-1 and AP-1 cooperate to increase gene expression in hypoxia: Role of MAP kinases
    • C. Michiels, E. Minet, G. Michel, D. Mottet, J.P. Piret, and M. Raes HIF-1 and AP-1 cooperate to increase gene expression in hypoxia: role of MAP kinases IUBMB Life 52 2001 49 53
    • (2001) IUBMB Life , vol.52 , pp. 49-53
    • Michiels, C.1    Minet, E.2    Michel, G.3    Mottet, D.4    Piret, J.P.5    Raes, M.6
  • 40
    • 0037206312 scopus 로고    scopus 로고
    • Two transactivation domains of hypoxia-inducible factor-1alpha regulated by the MEK-1/p42/p44 MAPK pathway
    • E. Lee, S. Yim, S.K. Lee, and H. Park Two transactivation domains of hypoxia-inducible factor-1alpha regulated by the MEK-1/p42/p44 MAPK pathway Mol. Cells 14 2002 9 15
    • (2002) Mol. Cells , vol.14 , pp. 9-15
    • Lee, E.1    Yim, S.2    Lee, S.K.3    Park, H.4
  • 42
    • 0036829987 scopus 로고    scopus 로고
    • Transcriptional induction of mitogen-activated protein kinase phosphatase 1 by retinoids. Selective roles of nuclear receptors and contribution to the antiapoptotic effect
    • Q. Xu, T. Konta, A. Furusu, K. Nakayama, J. Lucio-Cazana, L.G. Fine, and M. Kitamura Transcriptional induction of mitogen-activated protein kinase phosphatase 1 by retinoids. Selective roles of nuclear receptors and contribution to the antiapoptotic effect J. Biol. Chem. 277 2002 41693 41700
    • (2002) J. Biol. Chem. , vol.277 , pp. 41693-41700
    • Xu, Q.1    Konta, T.2    Furusu, A.3    Nakayama, K.4    Lucio-Cazana, J.5    Fine, L.G.6    Kitamura, M.7
  • 43
    • 0025120244 scopus 로고
    • Requirement for integration of signals from two distinct phosphorylation pathways for activation of MAP kinase
    • N.G. Anderson, J.L. Maller, N.K. Tonks, and T.W. Sturgill Requirement for integration of signals from two distinct phosphorylation pathways for activation of MAP kinase Nature 343 1990 651 653
    • (1990) Nature , vol.343 , pp. 651-653
    • Anderson, N.G.1    Maller, J.L.2    Tonks, N.K.3    Sturgill, T.W.4
  • 45
    • 0033081066 scopus 로고    scopus 로고
    • Nuclear translocation of p42/p44 mitogen-activated protein kinase is required for growth factor-induced gene expression and cell cycle entry
    • A. Brunet, D. Roux, P. Lenormand, S. Dowd, S. Keyse, and J. Pouyssegur Nuclear translocation of p42/p44 mitogen-activated protein kinase is required for growth factor-induced gene expression and cell cycle entry EMBO J. 18 1999 664 674
    • (1999) EMBO J. , vol.18 , pp. 664-674
    • Brunet, A.1    Roux, D.2    Lenormand, P.3    Dowd, S.4    Keyse, S.5    Pouyssegur, J.6
  • 46
    • 0034668924 scopus 로고    scopus 로고
    • Catalytic activation of mitogen-activated protein (MAP) kinase phosphatase-1 by binding to p38 MAP kinase: Critical role of the p38 C-terminal domain in its negative regulation
    • D. Hutter, P. Chen, J. Barnes, and Y. Liu Catalytic activation of mitogen-activated protein (MAP) kinase phosphatase-1 by binding to p38 MAP kinase: critical role of the p38 C-terminal domain in its negative regulation Biochem. J. 352 Pt. 1 2000 155 163
    • (2000) Biochem. J. , vol.352 , Issue.PART 1 , pp. 155-163
    • Hutter, D.1    Chen, P.2    Barnes, J.3    Liu, Y.4
  • 47
    • 0034176782 scopus 로고    scopus 로고
    • Exploiting the hypoxic cancer cell: Mechanisms and therapeutic strategies
    • J.M. Brown Exploiting the hypoxic cancer cell: mechanisms and therapeutic strategies Mol. Med. Today 6 2000 157 162
    • (2000) Mol. Med. Today , vol.6 , pp. 157-162
    • Brown, J.M.1
  • 48
    • 0141643358 scopus 로고    scopus 로고
    • Hypoxia up-regulates prolyl hydroxylase activity: A feedback mechanism that limits HIF-1 responses during reoxygenation
    • G. D'Angelo, E. Duplan, N. Boyer, P. Vigne, and C. Frelin Hypoxia up-regulates prolyl hydroxylase activity: a feedback mechanism that limits HIF-1 responses during reoxygenation J. Biol. Chem. 278 2003 38183 38187
    • (2003) J. Biol. Chem. , vol.278 , pp. 38183-38187
    • D'Angelo, G.1    Duplan, E.2    Boyer, N.3    Vigne, P.4    Frelin, C.5
  • 53
    • 0042763564 scopus 로고    scopus 로고
    • HIF-1 in cell cycle regulation, apoptosis, and tumor progression
    • N. Goda, S.J. Dozier, and R.S. Johnson HIF-1 in cell cycle regulation, apoptosis, and tumor progression Antioxid. Redox Signal. 5 2003 467 473
    • (2003) Antioxid. Redox Signal. , vol.5 , pp. 467-473
    • Goda, N.1    Dozier, S.J.2    Johnson, R.S.3
  • 54
    • 0036228789 scopus 로고    scopus 로고
    • Hypoxic induction of HIF-1alpha and VEGF expression in head and neck squamous cell carcinoma lines is mediated by stress activated protein kinases
    • B. Shemirani, and D.L. Crowe Hypoxic induction of HIF-1alpha and VEGF expression in head and neck squamous cell carcinoma lines is mediated by stress activated protein kinases Oral Oncol. 38 2002 251 257
    • (2002) Oral Oncol. , vol.38 , pp. 251-257
    • Shemirani, B.1    Crowe, D.L.2
  • 55
    • 20344386238 scopus 로고    scopus 로고
    • Mitochondrial reactive oxygen species activation of p38 mitogen-activated protein kinase is required for hypoxia signaling
    • B.M. Emerling, L.C. Platanias, E. Black, A.R. Nebreda, R.J. Davis, and N.S. Chandel Mitochondrial reactive oxygen species activation of p38 mitogen-activated protein kinase is required for hypoxia signaling Mol. Cell. Biol. 25 2005 4853 4862
    • (2005) Mol. Cell. Biol. , vol.25 , pp. 4853-4862
    • Emerling, B.M.1    Platanias, L.C.2    Black, E.3    Nebreda, A.R.4    Davis, R.J.5    Chandel, N.S.6
  • 56
    • 0037064010 scopus 로고    scopus 로고
    • Insulin-like growth factor 1 induces hypoxia-inducible factor 1-mediated vascular endothelial growth factor expression, which is dependent on MAP kinase and phosphatidylinositol 3-kinase signaling in colon cancer cells
    • R. Fukuda, K. Hirota, F. Fan, Y.D. Jung, L.M. Ellis, and G.L. Semenza Insulin-like growth factor 1 induces hypoxia-inducible factor 1-mediated vascular endothelial growth factor expression, which is dependent on MAP kinase and phosphatidylinositol 3-kinase signaling in colon cancer cells J. Biol. Chem. 277 2002 38205 38211
    • (2002) J. Biol. Chem. , vol.277 , pp. 38205-38211
    • Fukuda, R.1    Hirota, K.2    Fan, F.3    Jung, Y.D.4    Ellis, L.M.5    Semenza, G.L.6
  • 57
    • 2542443138 scopus 로고    scopus 로고
    • Epstein-Barr virus latent membrane protein 1 induces synthesis of hypoxia-inducible factor 1 alpha
    • N. Wakisaka, S. Kondo, T. Yoshizaki, S. Murono, M. Furukawa, and J.S. Pagano Epstein-Barr virus latent membrane protein 1 induces synthesis of hypoxia-inducible factor 1 alpha Mol. Cell. Biol. 24 2004 5223 5234
    • (2004) Mol. Cell. Biol. , vol.24 , pp. 5223-5234
    • Wakisaka, N.1    Kondo, S.2    Yoshizaki, T.3    Murono, S.4    Furukawa, M.5    Pagano, J.S.6


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