-
1
-
-
0030952289
-
Mechanisms of angiogenesis
-
W. Risau Mechanisms of angiogenesis Nature 386 1997 671 674
-
(1997)
Nature
, vol.386
, pp. 671-674
-
-
Risau, W.1
-
2
-
-
0032215354
-
VEGF gene delivery to muscle: Potential role for vasculogenesis in adults
-
M.L. Springer, A.S. Chen, P.E. Kraft, M. Bednarski, and H.M. Blau VEGF gene delivery to muscle: potential role for vasculogenesis in adults Mol. Cell 2 1998 549 558
-
(1998)
Mol. Cell
, vol.2
, pp. 549-558
-
-
Springer, M.L.1
Chen, A.S.2
Kraft, P.E.3
Bednarski, M.4
Blau, H.M.5
-
3
-
-
0034076189
-
Mechanisms of angiogenesis and arteriogenesis
-
P. Carmeliet Mechanisms of angiogenesis and arteriogenesis Nat. Med. 6 2000 389 395
-
(2000)
Nat. Med.
, vol.6
, pp. 389-395
-
-
Carmeliet, P.1
-
4
-
-
0030576517
-
Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis
-
D. Hanahan, and J. Folkman Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis Cell 86 1996 353 364
-
(1996)
Cell
, vol.86
, pp. 353-364
-
-
Hanahan, D.1
Folkman, J.2
-
5
-
-
0028929803
-
Angiogenesis in cancer, vascular, rheumatoid and other disease
-
J. Folkman Angiogenesis in cancer, vascular, rheumatoid and other disease Nat. Med. 1 1995 27 31
-
(1995)
Nat. Med.
, vol.1
, pp. 27-31
-
-
Folkman, J.1
-
6
-
-
0023157363
-
Angiogenic factors
-
J. Folkman, and M. Klagsbrun Angiogenic factors Science 235 1987 442 447
-
(1987)
Science
, vol.235
, pp. 442-447
-
-
Folkman, J.1
Klagsbrun, M.2
-
7
-
-
0021359304
-
Heparin affinity: Purification of a tumor-derived capillary endothelial cell growth factor
-
Y. Shing, J. Folkman, R. Sullivan, C. Butterfield, J. Murray, and M. Klagsbrun Heparin affinity: purification of a tumor-derived capillary endothelial cell growth factor Science 223 1984 1296 1299
-
(1984)
Science
, vol.223
, pp. 1296-1299
-
-
Shing, Y.1
Folkman, J.2
Sullivan, R.3
Butterfield, C.4
Murray, J.5
Klagsbrun, M.6
-
8
-
-
0034092011
-
Tumor angiogenesis: Past, present and the near future
-
R.S. Kerbel Tumor angiogenesis: past, present and the near future Carcinogenesis 21 2000 505 515
-
(2000)
Carcinogenesis
, vol.21
, pp. 505-515
-
-
Kerbel, R.S.1
-
9
-
-
0027288863
-
Distinct rat genes with related profiles of expression define a TIE receptor tyrosine kinase family
-
P.C. Maisonpierre, M. Goldfarb, G.D. Yancopoulos, and G. Gao Distinct rat genes with related profiles of expression define a TIE receptor tyrosine kinase family Oncogene 8 1993 1631 1637
-
(1993)
Oncogene
, vol.8
, pp. 1631-1637
-
-
Maisonpierre, P.C.1
Goldfarb, M.2
Yancopoulos, G.D.3
Gao, G.4
-
10
-
-
0030480322
-
Requisite role of angiopoietin-1, a ligand for the TIE2 receptor, during embryonic angiogenesis
-
C. Suri, P.F. Jones, S. Patan, S. Bartunkova, P.C. Maisonpierre, and S. Davis Requisite role of angiopoietin-1, a ligand for the TIE2 receptor, during embryonic angiogenesis Cell 87 1996 1171 1180
-
(1996)
Cell
, vol.87
, pp. 1171-1180
-
-
Suri, C.1
Jones, P.F.2
Patan, S.3
Bartunkova, S.4
Maisonpierre, P.C.5
Davis, S.6
-
11
-
-
15144358851
-
Angiopoietin-2, a natural antagonist for Tie2 that disrupts in vivo angiogenesis
-
P.C. Maisonpierre, C. Suri, P.F. Jones, S. Bartunkova, S.J. Wiegand, and C. Radziejewski Angiopoietin-2, a natural antagonist for Tie2 that disrupts in vivo angiogenesis Science 277 1997 55 60
-
(1997)
Science
, vol.277
, pp. 55-60
-
-
Maisonpierre, P.C.1
Suri, C.2
Jones, P.F.3
Bartunkova, S.4
Wiegand, S.J.5
Radziejewski, C.6
-
12
-
-
0034648793
-
Vascular-specific growth factors and blood vessel formation
-
G.D. Yancopoulos, S. Davis, N.W. Gale, J.S. Rudge, S.J. Wiegand, and J. Holash Vascular-specific growth factors and blood vessel formation Nature 407 2000 242 248
-
(2000)
Nature
, vol.407
, pp. 242-248
-
-
Yancopoulos, G.D.1
Davis, S.2
Gale, N.W.3
Rudge, J.S.4
Wiegand, S.J.5
Holash, J.6
-
13
-
-
0026485002
-
Vascular endothelial growth factor induced by hypoxia may mediate hypoxia-initiated angiogenesis
-
D. Shweiki, A. Itin, D. Soffer, and E. Keshet Vascular endothelial growth factor induced by hypoxia may mediate hypoxia-initiated angiogenesis Nature 359 1992 843 845
-
(1992)
Nature
, vol.359
, pp. 843-845
-
-
Shweiki, D.1
Itin, A.2
Soffer, D.3
Keshet, E.4
-
14
-
-
8844276697
-
Translating angiogenesis research into the clinic; The challenges ahead
-
H.G. Augustin Translating angiogenesis research into the clinic; the challenges ahead Br. J. Radiol. 76 2003 S3 S10
-
(2003)
Br. J. Radiol.
, vol.76
-
-
Augustin, H.G.1
-
15
-
-
0033542476
-
Activation of nitric oxide synthase in endothelial cells by Akt-dependent phosphorylation
-
S. Dimmeler, I. Fleming, B. Fisslthaler, C. Hermann, R. Busse, and A.M. Zeiher Activation of nitric oxide synthase in endothelial cells by Akt-dependent phosphorylation Nature 399 1999 601 605
-
(1999)
Nature
, vol.399
, pp. 601-605
-
-
Dimmeler, S.1
Fleming, I.2
Fisslthaler, B.3
Hermann, C.4
Busse, R.5
Zeiher, A.M.6
-
16
-
-
0033615069
-
The Akt kinase signals directly to endothelial nitric oxide synthase
-
B.J. Michell, J.E. Griffiths, K.I. Mitchelhill, I. Rodriguez-Crespo, T. Tiganis, and S. Bozinovski The Akt kinase signals directly to endothelial nitric oxide synthase Curr. Biol. 9 1999 845 848
-
(1999)
Curr. Biol.
, vol.9
, pp. 845-848
-
-
Michell, B.J.1
Griffiths, J.E.2
Mitchelhill, K.I.3
Rodriguez-Crespo, I.4
Tiganis, T.5
Bozinovski, S.6
-
17
-
-
0033542414
-
Regulation of endothelium-derived nitric oxide production by the protein kinase Akt
-
D. Fulton, J.P. Gratton, T.J. McCabe, J. Fontana, Y. Fujio, and K. Walsh Regulation of endothelium-derived nitric oxide production by the protein kinase Akt Nature 399 1999 597 601
-
(1999)
Nature
, vol.399
, pp. 597-601
-
-
Fulton, D.1
Gratton, J.P.2
McCabe, T.J.3
Fontana, J.4
Fujio, Y.5
Walsh, K.6
-
18
-
-
0041631006
-
Activation of the phosphatidylinositol 3-kinase/protein kinase Akt pathway mediates nitric oxide-induced endothelial cell migration and angiogenesis
-
K. Kawasaki, R.S. Smith Jr., C.M. Hsieh, J. Sun, J. Chao, and J.K. Liao Activation of the phosphatidylinositol 3-kinase/protein kinase Akt pathway mediates nitric oxide-induced endothelial cell migration and angiogenesis Mol. Cell Biol. 23 2003 5726 5737
-
(2003)
Mol. Cell Biol.
, vol.23
, pp. 5726-5737
-
-
Kawasaki, K.1
Smith Jr., R.S.2
Hsieh, C.M.3
Sun, J.4
Chao, J.5
Liao, J.K.6
-
19
-
-
0019855643
-
The p21 src genes of Harvey and Kirsten sarcoma viruses originate from divergent members of a family of normal vertebrate genes
-
R.W. Ellis, D. Defeo, T.Y. Shih, M.A. Gonda, H.A. Young, and N. Tsuchida The p21 src genes of Harvey and Kirsten sarcoma viruses originate from divergent members of a family of normal vertebrate genes Nature 292 1981 506 511
-
(1981)
Nature
, vol.292
, pp. 506-511
-
-
Ellis, R.W.1
Defeo, D.2
Shih, T.Y.3
Gonda, M.A.4
Young, H.A.5
Tsuchida, N.6
-
20
-
-
0019947771
-
Mechanism of activation of a human oncogene
-
C.J. Tabin, S.M. Bradley, C.I. Bargmann, R.A. Weinberg, A.G. Papageorge, and E.M. Scolnick Mechanism of activation of a human oncogene Nature 300 1982 143 149
-
(1982)
Nature
, vol.300
, pp. 143-149
-
-
Tabin, C.J.1
Bradley, S.M.2
Bargmann, C.I.3
Weinberg, R.A.4
Papageorge, A.G.5
Scolnick, E.M.6
-
21
-
-
0019960812
-
A point mutation is responsible for the acquisition of transforming properties by the T24 human bladder carcinoma oncogene
-
E.P. Reddy, R.K. Reynolds, E. Santos, and M. Barbacid A point mutation is responsible for the acquisition of transforming properties by the T24 human bladder carcinoma oncogene Nature 300 1982 149 152
-
(1982)
Nature
, vol.300
, pp. 149-152
-
-
Reddy, E.P.1
Reynolds, R.K.2
Santos, E.3
Barbacid, M.4
-
22
-
-
0020404981
-
Activation of the T24 bladder carcinoma transforming gene is linked to a single amino acid change
-
E. Taparowsky, Y. Suard, O. Fasano, K. Shimizu, M. Goldfarb, and M. Wigler Activation of the T24 bladder carcinoma transforming gene is linked to a single amino acid change Nature 300 1982 762 765
-
(1982)
Nature
, vol.300
, pp. 762-765
-
-
Taparowsky, E.1
Suard, Y.2
Fasano, O.3
Shimizu, K.4
Goldfarb, M.5
Wigler, M.6
-
23
-
-
0020624456
-
Activation of Ki-ras2 gene in human colon and lung carcinomas by two different point mutations
-
D.J. Capon, P.H. Seeburg, J.P. McGrath, J.S. Hayflick, U. Edman, A.D. Levinson, and D.V. Goeddel Activation of Ki-ras2 gene in human colon and lung carcinomas by two different point mutations Nature 304 1983 507 513
-
(1983)
Nature
, vol.304
, pp. 507-513
-
-
Capon, D.J.1
Seeburg, P.H.2
McGrath, J.P.3
Hayflick, J.S.4
Edman, U.5
Levinson, A.D.6
Goeddel, D.V.7
-
24
-
-
0020624455
-
Structure of the Ki-ras gene of the human lung carcinoma cell line Calu-1
-
K. Shimizu, D. Birnbaum, M.A. Ruley, O. Fasano, Y. Suard, and L. Edlund Structure of the Ki-ras gene of the human lung carcinoma cell line Calu-1 Nature 304 1983 497 500
-
(1983)
Nature
, vol.304
, pp. 497-500
-
-
Shimizu, K.1
Birnbaum, D.2
Ruley, M.A.3
Fasano, O.4
Suard, Y.5
Edlund, L.6
-
25
-
-
0020546075
-
Acquisition of transforming properties by alternative point mutations within c-bas/has human proto-oncogene
-
Y. Yuasa, S.K. Srivastava, C.Y. Dunn, J.S. Rhim, E.P. Reddy, and S.A. Aaronson Acquisition of transforming properties by alternative point mutations within c-bas/has human proto-oncogene Nature 303 1983 775 779
-
(1983)
Nature
, vol.303
, pp. 775-779
-
-
Yuasa, Y.1
Srivastava, S.K.2
Dunn, C.Y.3
Rhim, J.S.4
Reddy, E.P.5
Aaronson, S.A.6
-
26
-
-
0021830154
-
A novel ras-related gene family
-
P. Madaule, and R. Axel A novel ras-related gene family Cell 41 1985 31 40
-
(1985)
Cell
, vol.41
, pp. 31-40
-
-
Madaule, P.1
Axel, R.2
-
27
-
-
0036181428
-
The evolutionary history of effectors downstream of Cdc42 and Rac
-
S. Cotteret, and J. Chernoff The evolutionary history of effectors downstream of Cdc42 and Rac Genome Biol. 3 2 2002 1 8
-
(2002)
Genome Biol.
, vol.3
, Issue.2
, pp. 1-8
-
-
Cotteret, S.1
Chernoff, J.2
-
28
-
-
0842281652
-
Rho and Rac take center stage
-
K. Burridge, and K. Wennerberg Rho and Rac take center stage Cell 116 2004 167 179
-
(2004)
Cell
, vol.116
, pp. 167-179
-
-
Burridge, K.1
Wennerberg, K.2
-
29
-
-
0036364408
-
A growing family of guanine nucleotide exchange factors is responsible for activation of Ras-family GTPases
-
L.A. Quilliam, J.F. Rebhun, and A.F. Castro A growing family of guanine nucleotide exchange factors is responsible for activation of Ras-family GTPases Prog. Nucleic Acid Res. Mol. Biol. 71 2002 391 444
-
(2002)
Prog. Nucleic Acid Res. Mol. Biol.
, vol.71
, pp. 391-444
-
-
Quilliam, L.A.1
Rebhun, J.F.2
Castro, A.F.3
-
30
-
-
0037451803
-
GAPs galore! a survey of putative Ras superfamily GTPase activating proteins in man and Drosophila
-
A. Bernards GAPs galore! A survey of putative Ras superfamily GTPase activating proteins in man and Drosophila Biochim. Biophys. Acta 1603 2003 47 82
-
(2003)
Biochim. Biophys. Acta
, vol.1603
, pp. 47-82
-
-
Bernards, A.1
-
32
-
-
0037069690
-
Rho GTPases in cell biology
-
S. Etienne-Manneville, and A. Hall Rho GTPases in cell biology Nature 420 2002 629 635
-
(2002)
Nature
, vol.420
, pp. 629-635
-
-
Etienne-Manneville, S.1
Hall, A.2
-
33
-
-
0025078512
-
The cellular functions of small GTP-binding proteins
-
A. Hall The cellular functions of small GTP-binding proteins Science 249 1990 635 640
-
(1990)
Science
, vol.249
, pp. 635-640
-
-
Hall, A.1
-
34
-
-
0034644537
-
Ras and Rho GTPases: A family reunion
-
D. Bar-Sagi, and A. Hall Ras and Rho GTPases: a family reunion Cell 103 2000 227 238
-
(2000)
Cell
, vol.103
, pp. 227-238
-
-
Bar-Sagi, D.1
Hall, A.2
-
35
-
-
0035575585
-
Rho family proteins: Coordinating cell responses
-
A.J. Ridley Rho family proteins: coordinating cell responses Trends Cell Biol. 11 2001 471 477
-
(2001)
Trends Cell Biol.
, vol.11
, pp. 471-477
-
-
Ridley, A.J.1
-
36
-
-
0026778133
-
The small GTP-binding protein rho regulates the assembly of focal adhesions and actin stress fibers in response to growth factors
-
A.J. Ridley, and A. Hall The small GTP-binding protein rho regulates the assembly of focal adhesions and actin stress fibers in response to growth factors Cell 70 1992 389 399
-
(1992)
Cell
, vol.70
, pp. 389-399
-
-
Ridley, A.J.1
Hall, A.2
-
37
-
-
0026654125
-
The small GTP-binding protein rac regulates growth factor-induced membrane ruffling
-
A.J. Ridley, H.F. Paterson, C.L. Johnston, D. Diekmann, and A. Hall The small GTP-binding protein rac regulates growth factor-induced membrane ruffling Cell 70 1992 401 410
-
(1992)
Cell
, vol.70
, pp. 401-410
-
-
Ridley, A.J.1
Paterson, H.F.2
Johnston, C.L.3
Diekmann, D.4
Hall, A.5
-
39
-
-
0028961293
-
Rho, rac, and cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia, and filopodia
-
C.D. Nobes, and A. Hall Rho, rac, and cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia, and filopodia Cell 81 1995 53 62
-
(1995)
Cell
, vol.81
, pp. 53-62
-
-
Nobes, C.D.1
Hall, A.2
-
40
-
-
0034865456
-
Rho GTPases and cell migration
-
A.J. Ridley Rho GTPases and cell migration J. Cell Sci. 114 2001 2713 2722
-
(2001)
J. Cell Sci.
, vol.114
, pp. 2713-2722
-
-
Ridley, A.J.1
-
41
-
-
0034213327
-
Rho GTPases and their effector proteins
-
A.L. Bishop, and A. Hall Rho GTPases and their effector proteins Biochem. J. 2 348 Pt 2000 241 255
-
(2000)
Biochem. J.
, vol.2
, Issue.348 PART
, pp. 241-255
-
-
Bishop, A.L.1
Hall, A.2
-
42
-
-
0038554077
-
Biology of the p21-activated kinases
-
G.M. Bokoch Biology of the p21-activated kinases Annu. Rev. Biochem. 72 2003 743 781
-
(2003)
Annu. Rev. Biochem.
, vol.72
, pp. 743-781
-
-
Bokoch, G.M.1
-
43
-
-
0031105660
-
Human p21-activated kinase (Pak1) regulates actin organization in mammalian cells
-
M.A. Sells, U.G. Knaus, S. Bagrodia, D.M. Ambrose, G.M. Bokoch, and J. Chernoff Human p21-activated kinase (Pak1) regulates actin organization in mammalian cells Curr. Biol. 7 1997 202 210
-
(1997)
Curr. Biol.
, vol.7
, pp. 202-210
-
-
Sells, M.A.1
Knaus, U.G.2
Bagrodia, S.3
Ambrose, D.M.4
Bokoch, G.M.5
Chernoff, J.6
-
44
-
-
0027048684
-
The protein kinase homologue Ste20p is required to link the yeast pheromone response G-protein beta gamma subunits to downstream signalling components
-
E. Leberer, D. Dignard, D. Harcus, D.Y. Thomas, and M. Whiteway The protein kinase homologue Ste20p is required to link the yeast pheromone response G-protein beta gamma subunits to downstream signalling components Eur. Mol. Biol. Org. J. 11 1992 4815 4824
-
(1992)
Eur. Mol. Biol. Org. J.
, vol.11
, pp. 4815-4824
-
-
Leberer, E.1
Dignard, D.2
Harcus, D.3
Thomas, D.Y.4
Whiteway, M.5
-
45
-
-
0019888587
-
Cyclic Nucleotide-independent protein kinases from rabbit reticulocytes. Identification and characterization of a protein kinase activated by proteolysis
-
S.M. Tahara, and J.A. Traugh Cyclic Nucleotide-independent protein kinases from rabbit reticulocytes. Identification and characterization of a protein kinase activated by proteolysis J. Biol. Chem. 256 1981 11558 11564
-
(1981)
J. Biol. Chem.
, vol.256
, pp. 11558-11564
-
-
Tahara, S.M.1
Traugh, J.A.2
-
46
-
-
0020380708
-
2+-stimulated protease and identification of phosphorylated translational components
-
2+-stimulated protease and identification of phosphorylated translational components Eur. J. Biochem. 126 1982 395 399
-
(1982)
Eur. J. Biochem.
, vol.126
, pp. 395-399
-
-
Tahara, S.M.1
Traugh, J.A.2
-
47
-
-
0028078824
-
A brain serine/threonine protein kinase activated by Cdc42 and Rac1
-
E. Manser, T. Leung, H. Salihuddin, Z.S. Zhao, and L. Lim A brain serine/threonine protein kinase activated by Cdc42 and Rac1 Nature 367 1994 40 46
-
(1994)
Nature
, vol.367
, pp. 40-46
-
-
Manser, E.1
Leung, T.2
Salihuddin, H.3
Zhao, Z.S.4
Lim, L.5
-
48
-
-
0028842508
-
Identification and molecular cloning of a p21cdc42/rac1-activated serine/threonine kinase that is rapidly activated by thrombin in platelets
-
M. Teo, E. Manser, and L. Lim Identification and molecular cloning of a p21cdc42/rac1-activated serine/threonine kinase that is rapidly activated by thrombin in platelets J. Biol. Chem. 270 1995 26690 26697
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 26690-26697
-
-
Teo, M.1
Manser, E.2
Lim, L.3
-
49
-
-
0028862297
-
Molecular cloning of a new member of the p21-Cdc42/Rac-activated kinase (PAK) family
-
E. Manser, C. Chong, Z.S. Zhao, T. Leung, G. Michael, C. Hall, and L. Lim Molecular cloning of a new member of the p21-Cdc42/Rac-activated kinase (PAK) family J. Biol. Chem. 270 1995 25070 25078
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 25070-25078
-
-
Manser, E.1
Chong, C.2
Zhao, Z.S.3
Leung, T.4
Michael, G.5
Hall, C.6
Lim, L.7
-
51
-
-
0029911521
-
Interaction of the Nck adapter protein with p21-activated kinase (PAK1)
-
G.M. Bokoch, Y. Wang, B.P. Bohl, M.A. Sells, L.A. Quilliam, and U.G. Knaus Interaction of the Nck adapter protein with p21-activated kinase (PAK1) J. Biol. Chem. 271 1996 25746 25749
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 25746-25749
-
-
Bokoch, G.M.1
Wang, Y.2
Bohl, B.P.3
Sells, M.A.4
Quilliam, L.A.5
Knaus, U.G.6
-
52
-
-
0031610579
-
PAK kinases are directly coupled to the PIX family of nucleotide exchange factors
-
E. Manser, T.H. Loo, C.G. Koh, Z.S. Zhao, X.Q. Chen, and L. Tan PAK kinases are directly coupled to the PIX family of nucleotide exchange factors Mol. Cell 1 1998 183 192
-
(1998)
Mol. Cell
, vol.1
, pp. 183-192
-
-
Manser, E.1
Loo, T.H.2
Koh, C.G.3
Zhao, Z.S.4
Chen, X.Q.5
Tan, L.6
-
53
-
-
0038660689
-
P21-activated kinase 1 (PAK1) interacts with the Grb2 adapter protein to couple to growth factor signaling
-
L.A. Puto, K. Pestonjamasp, C.C. King, and G.M. Bokoch p21-activated kinase 1 (PAK1) interacts with the Grb2 adapter protein to couple to growth factor signaling J. Biol. Chem. 278 2003 9388 9393
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 9388-9393
-
-
Puto, L.A.1
Pestonjamasp, K.2
King, C.C.3
Bokoch, G.M.4
-
54
-
-
0032508636
-
A novel regulator of p21-activated kinases
-
S. Bagrodia, S.J. Taylor, K.A. Jordon, L. Van Aelst, and R.A. Cerione A novel regulator of p21-activated kinases J. Biol. Chem. 273 1998 23633 23636
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 23633-23636
-
-
Bagrodia, S.1
Taylor, S.J.2
Jordon, K.A.3
Van Aelst, L.4
Cerione, R.A.5
-
55
-
-
0032479975
-
PAK promotes morphological changes by acting upstream of Rac
-
A. Obermeier, S. Ahmed, E. Manser, S.C. Yen, C. Hall, and L. Lim PAK promotes morphological changes by acting upstream of Rac Eur. Mol. Biol. Org. J. 17 1998 4328 4339
-
(1998)
Eur. Mol. Biol. Org. J.
, vol.17
, pp. 4328-4339
-
-
Obermeier, A.1
Ahmed, S.2
Manser, E.3
Yen, S.C.4
Hall, C.5
Lim, L.6
-
56
-
-
85013312416
-
Tumor angiogenesis: Therapeutic implications
-
J. Folkman Tumor angiogenesis: therapeutic implications N. Engl. J. Med. 285 1971 1182 1186
-
(1971)
N. Engl. J. Med.
, vol.285
, pp. 1182-1186
-
-
Folkman, J.1
-
57
-
-
0030968580
-
Rho GTPases and signaling networks
-
L. Van Aelst, and C. D'Souza-Schorey Rho GTPases and signaling networks Genes Dev. 11 1997 2295 2322
-
(1997)
Genes Dev.
, vol.11
, pp. 2295-2322
-
-
Van Aelst, L.1
D'Souza-Schorey, C.2
-
58
-
-
0344305784
-
Cell migration: Integrating signals from front to back
-
A.J. Ridley, M.A. Schwartz, K. Burridge, R.A. Firtel, M.H. Ginsberg, and G. Borisy Cell migration: integrating signals from front to back Science 302 2003 1704 1709
-
(2003)
Science
, vol.302
, pp. 1704-1709
-
-
Ridley, A.J.1
Schwartz, M.A.2
Burridge, K.3
Firtel, R.A.4
Ginsberg, M.H.5
Borisy, G.6
-
59
-
-
0035840155
-
Rho family GTPases regulate VEGF-stimulated endothelial cell motility
-
N. Soga, N. Namba, S. McAllister, L. Cornelius, S.L. Teitelbaum, and S.F. Dowdy Rho family GTPases regulate VEGF-stimulated endothelial cell motility Exp. Cell Res. 269 2001 73 87
-
(2001)
Exp. Cell Res.
, vol.269
, pp. 73-87
-
-
Soga, N.1
Namba, N.2
McAllister, S.3
Cornelius, L.4
Teitelbaum, S.L.5
Dowdy, S.F.6
-
60
-
-
0035672899
-
Rac regulates vascular endothelial growth factor stimulated motility
-
N. Soga, J.O. Connolly, M. Chellaiah, J. Kawamura, and K.A. Hruska Rac regulates vascular endothelial growth factor stimulated motility Cell Commun. Adhes. 8 2001 1 13
-
(2001)
Cell Commun. Adhes.
, vol.8
, pp. 1-13
-
-
Soga, N.1
Connolly, J.O.2
Chellaiah, M.3
Kawamura, J.4
Hruska, K.A.5
-
61
-
-
2642615752
-
Regulation of TNF-alpha-induced reorganization of the actin cytoskeleton and cell-cell junctions by Rho. Rac, and Cdc42 in human endothelial cells
-
B. Wojciak-Stothard, A. Entwistle, R. Garg, and A.J. Ridley Regulation of TNF-alpha-induced reorganization of the actin cytoskeleton and cell-cell junctions by Rho. Rac, and Cdc42 in human endothelial cells J. Cell Physiol. 176 1998 150 165
-
(1998)
J. Cell Physiol.
, vol.176
, pp. 150-165
-
-
Wojciak-Stothard, B.1
Entwistle, A.2
Garg, R.3
Ridley, A.J.4
-
62
-
-
0037092520
-
Differential regulation of Rho GTPases by beta1 and beta3 integrins: The role of an extracellular domain of integrin in intracellular signaling
-
H. Miao, S. Li, Y.L. Hu, S. Yuan, Y. Zhao, and B.P. Chen Differential regulation of Rho GTPases by beta1 and beta3 integrins: the role of an extracellular domain of integrin in intracellular signaling J. Cell Sci. 115 2002 2199 2206
-
(2002)
J. Cell Sci.
, vol.115
, pp. 2199-2206
-
-
Miao, H.1
Li, S.2
Hu, Y.L.3
Yuan, S.4
Zhao, Y.5
Chen, B.P.6
-
64
-
-
0042344706
-
Rho GTPases and the regulation of endothelial permeability
-
B. Wojciak-Stothard, and A.J. Ridley Rho GTPases and the regulation of endothelial permeability Vascul. Pharmacol. 39 2002 187 199
-
(2002)
Vascul. Pharmacol.
, vol.39
, pp. 187-199
-
-
Wojciak-Stothard, B.1
Ridley, A.J.2
-
65
-
-
0037731922
-
Shear stress-induced endothelial cell polarization is mediated by Rho and Rac but not Cdc42 or PI 3-kinases
-
B. Wojciak-Stothard, and A.J. Ridley Shear stress-induced endothelial cell polarization is mediated by Rho and Rac but not Cdc42 or PI 3-kinases J. Cell Biol. 161 2003 429 439
-
(2003)
J. Cell Biol.
, vol.161
, pp. 429-439
-
-
Wojciak-Stothard, B.1
Ridley, A.J.2
-
67
-
-
0036325594
-
Rac regulates endothelial morphogenesis and capillary assembly
-
J.O. Connolly, N. Simpson, L. Hewlett, and A. Hall Rac regulates endothelial morphogenesis and capillary assembly Mol. Biol. Cell 13 2002 2474 2485
-
(2002)
Mol. Biol. Cell
, vol.13
, pp. 2474-2485
-
-
Connolly, J.O.1
Simpson, N.2
Hewlett, L.3
Hall, A.4
-
68
-
-
0037087648
-
The Cdc42 and Rac1 GTPases are required for capillary lumen formation in three-dimensional extracellular matrices
-
K.J. Bayless, and G.E. Davis The Cdc42 and Rac1 GTPases are required for capillary lumen formation in three-dimensional extracellular matrices J. Cell. Sci. 115 2002 1123 1136
-
(2002)
J. Cell. Sci.
, vol.115
, pp. 1123-1136
-
-
Bayless, K.J.1
Davis, G.E.2
-
69
-
-
0037465790
-
Small GTP-binding protein Rac is an essential mediator of vascular endothelial growth factor-induced endothelial fenestrations and vascular permeability
-
A. Eriksson, R. Cao, J. Roy, K. Tritsaris, C. Wahlestedt, and S. Dissing Small GTP-binding protein Rac is an essential mediator of vascular endothelial growth factor-induced endothelial fenestrations and vascular permeability Circulation 107 2003 1532 1538
-
(2003)
Circulation
, vol.107
, pp. 1532-1538
-
-
Eriksson, A.1
Cao, R.2
Roy, J.3
Tritsaris, K.4
Wahlestedt, C.5
Dissing, S.6
-
71
-
-
0345737070
-
Requirement of Rac activity for maintenance of capillary endothelial barrier properties
-
J. Waschke, W. Baumgartner, R.H. Adamson, M. Zeng, K. Aktories, and H. Barth Requirement of Rac activity for maintenance of capillary endothelial barrier properties Am. J. Physiol. Heart Circ. Physiol. 286 2004 H394 H401
-
(2004)
Am. J. Physiol. Heart Circ. Physiol.
, vol.286
-
-
Waschke, J.1
Baumgartner, W.2
Adamson, R.H.3
Zeng, M.4
Aktories, K.5
Barth, H.6
-
72
-
-
3142534324
-
A critical period requiring Rho proteins for cell cycle progression uncovered by reversible protein transduction in endothelial cells
-
K. Hirano, M. Hirano, J. Nishimura, and H. Kanaide A critical period requiring Rho proteins for cell cycle progression uncovered by reversible protein transduction in endothelial cells Fed. Eur. Biol. Soc. Lett 570 2004 149 154
-
(2004)
Fed. Eur. Biol. Soc. Lett
, vol.570
, pp. 149-154
-
-
Hirano, K.1
Hirano, M.2
Nishimura, J.3
Kanaide, H.4
-
73
-
-
7244242279
-
The small GTPase Rac1 links the Kaposi sarcoma-associated herpesvirus vGPCR to cytokine secretion and paracrine neoplasia
-
S. Montaner, A. Sodhi, J.-M. Servitja, A.K. Ramsdell, A. Barac, E.T. Sawai, and J.S. Gutkind The small GTPase Rac1 links the Kaposi sarcoma-associated herpesvirus vGPCR to cytokine secretion and paracrine neoplasia Blood 104 2004 2903 2911
-
(2004)
Blood
, vol.104
, pp. 2903-2911
-
-
Montaner, S.1
Sodhi, A.2
Servitja, J.-M.3
Ramsdell, A.K.4
Barac, A.5
Sawai, E.T.6
Gutkind, J.S.7
-
74
-
-
0346690266
-
Activation of p21-activated kinase 1-nuclear factor kappaB signaling by Kaposi's sarcoma-associated herpes virus G protein-coupled receptor during cellular transformation
-
D. Dadke, B.H. Fryer, E.A. Golemis, and J. Field Activation of p21-activated kinase 1-nuclear factor kappaB signaling by Kaposi's sarcoma-associated herpes virus G protein-coupled receptor during cellular transformation Cancer Res. 63 2003 8837 8847
-
(2003)
Cancer Res.
, vol.63
, pp. 8837-8847
-
-
Dadke, D.1
Fryer, B.H.2
Golemis, E.A.3
Field, J.4
-
75
-
-
0042386426
-
Differential alphav integrin-mediated Ras-ERK signaling during two pathways of angiogenesis
-
J.D. Hood, R. Frausto, W.B. Kiosses, M.A. Schwartz, and D.A. Cheresh Differential alphav integrin-mediated Ras-ERK signaling during two pathways of angiogenesis J. Cell Biol. 162 2003 933 943
-
(2003)
J. Cell Biol.
, vol.162
, pp. 933-943
-
-
Hood, J.D.1
Frausto, R.2
Kiosses, W.B.3
Schwartz, M.A.4
Cheresh, D.A.5
-
76
-
-
0038724937
-
Role of Raf in vascular protection from distinct apoptotic stimuli
-
A. Alavi, J.D. Hood, R. Frausto, D.G. Stupack, and D.A. Cheresh Role of Raf in vascular protection from distinct apoptotic stimuli Science 301 2003 94 96
-
(2003)
Science
, vol.301
, pp. 94-96
-
-
Alavi, A.1
Hood, J.D.2
Frausto, R.3
Stupack, D.G.4
Cheresh, D.A.5
-
77
-
-
0033571033
-
A role for p21-activated kinase in endothelial cell migration
-
W.B. Kiosses, R.H. Daniels, C. Otey, G.M. Bokoch, and M.A. Schwartz A role for p21-activated kinase in endothelial cell migration J. Cell Biol. 147 1999 831 844
-
(1999)
J. Cell Biol.
, vol.147
, pp. 831-844
-
-
Kiosses, W.B.1
Daniels, R.H.2
Otey, C.3
Bokoch, G.M.4
Schwartz, M.A.5
-
78
-
-
4444251392
-
Role of focal adhesion formation in migration and morphogenesis of endothelial cells
-
S. Kanda, Y. Miyata, and H. Kanetake Role of focal adhesion formation in migration and morphogenesis of endothelial cells Cell Signal. 16 2004 1273 1281
-
(2004)
Cell Signal.
, vol.16
, pp. 1273-1281
-
-
Kanda, S.1
Miyata, Y.2
Kanetake, H.3
-
79
-
-
0037023648
-
A dominant-negative p65 PAK peptide inhibits angiogenesis
-
W.B. Kiosses, J. Hood, S. Yang, M.E. Gerritsen, D.A. Cheresh, N. Alderson, and M.A. Schwartz A dominant-negative p65 PAK peptide inhibits angiogenesis Circ. Res. 90 2002 697 702
-
(2002)
Circ. Res.
, vol.90
, pp. 697-702
-
-
Kiosses, W.B.1
Hood, J.2
Yang, S.3
Gerritsen, M.E.4
Cheresh, D.A.5
Alderson, N.6
Schwartz, M.A.7
-
80
-
-
0035933713
-
NCK and PAK participate in the signaling pathway by which vascular endothelial growth factor stimulates the assembly of focal adhesions
-
K.V. Stoletov, K.E. Ratcliffe, S.C. Spring, and B.I. Terman NCK and PAK participate in the signaling pathway by which vascular endothelial growth factor stimulates the assembly of focal adhesions J. Biol. Chem. 276 2001 22748 22755
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 22748-22755
-
-
Stoletov, K.V.1
Ratcliffe, K.E.2
Spring, S.C.3
Terman, B.I.4
-
81
-
-
8744274131
-
PAK regulates endothelial permeability through modulation of contractility
-
R.A. Stockton, E. Schaefer, and M. Alexander Schwartz PAK regulates endothelial permeability through modulation of contractility J. Biol. Chem. 279 2004 46621 46630
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 46621-46630
-
-
Stockton, R.A.1
Schaefer, E.2
Alexander Schwartz, M.3
-
82
-
-
0034282225
-
Regulation of anchorage-dependent signal transduction by protein kinase a and p21-activated kinase
-
A.K. Howe, and R.L. Juliano Regulation of anchorage-dependent signal transduction by protein kinase A and p21-activated kinase Nat. Cell Biol. 2 2000 593 600
-
(2000)
Nat. Cell Biol.
, vol.2
, pp. 593-600
-
-
Howe, A.K.1
Juliano, R.L.2
-
83
-
-
0034731505
-
P21-activated kinase (PAK1) is phosphorylated and activated by 3-phosphoinositide-dependent kinase-1 (PDK1)
-
C.C. King, E.M. Gardiner, F.T. Zenke, B.P. Bohl, A.C. Newton, B.A. Hemmings, and G.M. Bokoch p21-activated kinase (PAK1) is phosphorylated and activated by 3-phosphoinositide-dependent kinase-1 (PDK1) J. Biol. Chem. 275 2000 41201 41209
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 41201-41209
-
-
King, C.C.1
Gardiner, E.M.2
Zenke, F.T.3
Bohl, B.P.4
Newton, A.C.5
Hemmings, B.A.6
Bokoch, G.M.7
-
84
-
-
0034737807
-
The Akt proto-oncogene links Ras to Pak and cell survival signals
-
Y. Tang, H. Zhou, A. Chen, R.N. Pittman, and J. Field The Akt proto-oncogene links Ras to Pak and cell survival signals J. Biol. Chem. 275 2000 9106 9109
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 9106-9109
-
-
Tang, Y.1
Zhou, H.2
Chen, A.3
Pittman, R.N.4
Field, J.5
-
85
-
-
0242664130
-
Akt phosphorylation of serine 21 on Pak1 modulates Nck binding and cell migration
-
G.L. Zhou, Y. Zhuo, C.C. King, B.H. Fryer, G.M. Bokoch, and J. Field Akt phosphorylation of serine 21 on Pak1 modulates Nck binding and cell migration Mol. Cell Biol. 23 2003 8058 8069
-
(2003)
Mol. Cell Biol.
, vol.23
, pp. 8058-8069
-
-
Zhou, G.L.1
Zhuo, Y.2
King, C.C.3
Fryer, B.H.4
Bokoch, G.M.5
Field, J.6
-
86
-
-
2942715062
-
Activation of the small GTPase Rac1 by cGMP-dependent protein kinase
-
Y. Hou, R.D. Ye, and D.D. Browning Activation of the small GTPase Rac1 by cGMP-dependent protein kinase Cell Signal. 16 2004 1061 1069
-
(2004)
Cell Signal.
, vol.16
, pp. 1061-1069
-
-
Hou, Y.1
Ye, R.D.2
Browning, D.D.3
-
87
-
-
0024361274
-
The cDNA of the two isoforms of bovine cGMP-dependent protein kinase
-
W. Wernet, V. Flockerzi, and F. Hofmann The cDNA of the two isoforms of bovine cGMP-dependent protein kinase Fed. Eur. Biol. Soc. Lett. 251 1989 191 196
-
(1989)
Fed. Eur. Biol. Soc. Lett.
, vol.251
, pp. 191-196
-
-
Wernet, W.1
Flockerzi, V.2
Hofmann, F.3
-
88
-
-
0024325064
-
Molecular cloning and predicted full-length amino acid sequence of the type I beta isozyme of cGMP-dependent protein kinase from human placenta. Tissue distribution and developmental changes in rat.
-
M. Sandberg, V. Natarajan, I. Ronander, D. Kalderon, U. Walter, S.M. Lohmann, and T. Jahnsen Molecular cloning and predicted full-length amino acid sequence of the type I beta isozyme of cGMP-dependent protein kinase from human placenta. Tissue distribution and developmental changes in rat. Fed. Eur. Biol. Soc. Lett. 255 1989 321 329
-
(1989)
Fed. Eur. Biol. Soc. Lett.
, vol.255
, pp. 321-329
-
-
Sandberg, M.1
Natarajan, V.2
Ronander, I.3
Kalderon, D.4
Walter, U.5
Lohmann, S.M.6
Jahnsen, T.7
-
89
-
-
0027519350
-
Cloning and expression of a novel cyclic GMP-dependent protein kinase from mouse brain
-
M.D. Uhler Cloning and expression of a novel cyclic GMP-dependent protein kinase from mouse brain J. Biol. Chem. 268 1993 13586 13591
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 13586-13591
-
-
Uhler, M.D.1
-
90
-
-
0027965908
-
Cloning, expression, and in situ localization of rat intestinal cGMP-dependent protein kinase II
-
T. Jarchau, C. Hausler, T. Markert, D. Pohler, J. Vanderkerckhove, and H.R. De Jonge Cloning, expression, and in situ localization of rat intestinal cGMP-dependent protein kinase II Proc. Natl Acad. Sci. USA 91 1994 9426 9430
-
(1994)
Proc. Natl Acad. Sci. USA
, vol.91
, pp. 9426-9430
-
-
Jarchau, T.1
Hausler, C.2
Markert, T.3
Pohler, D.4
Vanderkerckhove, J.5
De Jonge, H.R.6
-
91
-
-
0031842130
-
Functional analysis of cGMP-dependent protein kinases I and II as mediators of NO/cGMP effects
-
A. Smolenski, A.M. Burkhardt, M. Eigenthaler, E. Butt, S. Gambaryan, S.M. Lohmann, and U. Walter Functional analysis of cGMP-dependent protein kinases I and II as mediators of NO/cGMP effects Naunyn Schmiedebergs Arch. Pharmacol. 358 1998 134 139
-
(1998)
Naunyn Schmiedebergs Arch. Pharmacol.
, vol.358
, pp. 134-139
-
-
Smolenski, A.1
Burkhardt, A.M.2
Eigenthaler, M.3
Butt, E.4
Gambaryan, S.5
Lohmann, S.M.6
Walter, U.7
-
92
-
-
0034614502
-
Distinguishing the roles of the two different cGMP-binding sites for modulating phosphorylation of exogenous substrate (heterophosphorylation) and autophosphorylation of cGMP-dependent protein kinase
-
J.A. Smith, R.B. Reed, S.H. Francis, K. Grimes, and J.D. Corbin Distinguishing the roles of the two different cGMP-binding sites for modulating phosphorylation of exogenous substrate (heterophosphorylation) and autophosphorylation of cGMP-dependent protein kinase J. Biol. Chem. 275 2000 154 158
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 154-158
-
-
Smith, J.A.1
Reed, R.B.2
Francis, S.H.3
Grimes, K.4
Corbin, J.D.5
-
93
-
-
0023505509
-
Endothelium-derived relaxing factor produced and released from artery and vein is nitric oxide
-
L.J. Ignarro, G.M. Buga, K.S. Wood, R.E. Byrns, and G. Chaudhuri Endothelium-derived relaxing factor produced and released from artery and vein is nitric oxide Proc. Natl Acad. Sci. USA 84 1987 9265 9269
-
(1987)
Proc. Natl Acad. Sci. USA
, vol.84
, pp. 9265-9269
-
-
Ignarro, L.J.1
Buga, G.M.2
Wood, K.S.3
Byrns, R.E.4
Chaudhuri, G.5
-
94
-
-
0023145898
-
Endothelium-dependent modulation of cGMP levels and intrinsic smooth muscle tone in isolated bovine intrapulmonary artery and vein
-
L.J. Ignarro, R.E. Byrns, and K.S. Wood Endothelium-dependent modulation of cGMP levels and intrinsic smooth muscle tone in isolated bovine intrapulmonary artery and vein Circ. Res. 60 1987 82 92
-
(1987)
Circ. Res.
, vol.60
, pp. 82-92
-
-
Ignarro, L.J.1
Byrns, R.E.2
Wood, K.S.3
-
95
-
-
0023224441
-
Effects of glyceryl trinitrate on endothelium-dependent and -independent relaxation and cyclic GMP levels in rat aorta and human coronary artery
-
R.M. Rapoport, S.A. Waldman, R. Ginsburg, C.R. Molina, and F. Murad Effects of glyceryl trinitrate on endothelium-dependent and -independent relaxation and cyclic GMP levels in rat aorta and human coronary artery J. Cardiovasc. Pharmacol. 10 1987 82 89
-
(1987)
J. Cardiovasc. Pharmacol.
, vol.10
, pp. 82-89
-
-
Rapoport, R.M.1
Waldman, S.A.2
Ginsburg, R.3
Molina, C.R.4
Murad, F.5
-
96
-
-
0035069096
-
Natriuretic peptide signalling: Molecular and cellular pathways to growth regulation
-
M. Silberbach, and C.T. Roberts Jr. Natriuretic peptide signalling: molecular and cellular pathways to growth regulation Cell Signal. 13 2001 221 231
-
(2001)
Cell Signal.
, vol.13
, pp. 221-231
-
-
Silberbach, M.1
Roberts Jr., C.T.2
-
97
-
-
0042859823
-
Cyclic GMP phosphodiesterases and regulation of smooth muscle function
-
S.D. Rybalkin, C. Yan, K.E. Bornfeldt, and J.A. Beavo Cyclic GMP phosphodiesterases and regulation of smooth muscle function Circ. Res. 93 2003 280 291
-
(2003)
Circ. Res.
, vol.93
, pp. 280-291
-
-
Rybalkin, S.D.1
Yan, C.2
Bornfeldt, K.E.3
Beavo, J.A.4
-
98
-
-
0033974164
-
Impaired relaxation of stomach smooth muscle in mice lacking cyclic GMP-dependent protein kinase I
-
L. Ny, A. Pfeifer, A. Aszodi, M. Ahmad, P. Alm, and P. Hedlund Impaired relaxation of stomach smooth muscle in mice lacking cyclic GMP-dependent protein kinase I Br. J. Pharmacol. 129 2000 395 401
-
(2000)
Br. J. Pharmacol.
, vol.129
, pp. 395-401
-
-
Ny, L.1
Pfeifer, A.2
Aszodi, A.3
Ahmad, M.4
Alm, P.5
Hedlund, P.6
-
99
-
-
0030956837
-
Elastin-derived peptide induces monocyte chemotaxis by increasing intracellular cyclic GMP level and activating cyclic GMP dependent protein kinase
-
Y. Uemura, and K. Okamoto Elastin-derived peptide induces monocyte chemotaxis by increasing intracellular cyclic GMP level and activating cyclic GMP dependent protein kinase Biochem. Mol. Biol. Int. 41 1997 1085 1092
-
(1997)
Biochem. Mol. Biol. Int.
, vol.41
, pp. 1085-1092
-
-
Uemura, Y.1
Okamoto, K.2
-
100
-
-
0034764103
-
Differential phosphodiesterase activity contributes to restrictive endothelial barrier function during angiogenesis
-
L.M. DeFouw, and D.O. DeFouw Differential phosphodiesterase activity contributes to restrictive endothelial barrier function during angiogenesis Microvasc. Res. 62 2001 263 270
-
(2001)
Microvasc. Res.
, vol.62
, pp. 263-270
-
-
Defouw, L.M.1
Defouw, D.O.2
-
101
-
-
0343844156
-
The role of cyclic nucleotides in neutrophil migration
-
J.G. Elferink, and B.E. VanUffelen The role of cyclic nucleotides in neutrophil migration Gen. Pharmacol. 27 1996 387 393
-
(1996)
Gen. Pharmacol.
, vol.27
, pp. 387-393
-
-
Elferink, J.G.1
Vanuffelen, B.E.2
-
102
-
-
0033583481
-
Increased adhesion and aggregation of platelets lacking cyclic guanosine 3′,5′-monophosphate kinase I
-
S. Massberg, M. Sausbier, P. Klatt, M. Bauer, A. Pfeifer, and W. Siess Increased adhesion and aggregation of platelets lacking cyclic guanosine 3′,5′-monophosphate kinase I J. Exp. Med. 189 1999 1255 1264
-
(1999)
J. Exp. Med.
, vol.189
, pp. 1255-1264
-
-
Massberg, S.1
Sausbier, M.2
Klatt, P.3
Bauer, M.4
Pfeifer, A.5
Siess, W.6
-
103
-
-
0037428145
-
A stimulatory role for cGMP-dependent protein kinase in platelet activation
-
Z. Li, X. Xi, M. Gu, R. Feil, R.D. Ye, and M. Eigenthaler A stimulatory role for cGMP-dependent protein kinase in platelet activation Cell 112 2003 77 86
-
(2003)
Cell
, vol.112
, pp. 77-86
-
-
Li, Z.1
Xi, X.2
Gu, M.3
Feil, R.4
Ye, R.D.5
Eigenthaler, M.6
-
104
-
-
0037064574
-
CGMP-mediated signaling via cGKIalpha is required for the guidance and connectivity of sensory axons
-
H. Schmidt, M. Werner, P.A. Heppenstall, M. Henning, M.I. More, S. Kuhbandner, and F.G. Rathjen cGMP-mediated signaling via cGKIalpha is required for the guidance and connectivity of sensory axons J. Cell Biol. 159 2002 489 498
-
(2002)
J. Cell Biol.
, vol.159
, pp. 489-498
-
-
Schmidt, H.1
Werner, M.2
Heppenstall, P.A.3
Henning, M.4
More, M.I.5
Kuhbandner, S.6
Rathjen, F.G.7
-
105
-
-
0037378364
-
Physiological concentration of atrial natriuretic peptide induces endothelial regeneration in vitro
-
H. Kook, H. Itoh, B.S. Choi, N. Sawada, K. Doi, and T.J. Hwang Physiological concentration of atrial natriuretic peptide induces endothelial regeneration in vitro Am. J. Physiol. Heart Circ. Physiol. 284 2003 H1388 H1397
-
(2003)
Am. J. Physiol. Heart Circ. Physiol.
, vol.284
-
-
Kook, H.1
Itoh, H.2
Choi, B.S.3
Sawada, N.4
Doi, K.5
Hwang, T.J.6
-
106
-
-
0037452937
-
Significance and therapeutic potential of the natriuretic peptides/cGMP/cGMP-dependent protein kinase pathway in vascular regeneration
-
K. Yamahara, H. Itoh, T.H. Chun, Y. Ogawa, J. Yamashita, and N. Sawada Significance and therapeutic potential of the natriuretic peptides/cGMP/cGMP- dependent protein kinase pathway in vascular regeneration Proc. Natl Acad. Sci. USA 100 2003 3404 3409
-
(2003)
Proc. Natl Acad. Sci. USA
, vol.100
, pp. 3404-3409
-
-
Yamahara, K.1
Itoh, H.2
Chun, T.H.3
Ogawa, Y.4
Yamashita, J.5
Sawada, N.6
-
107
-
-
0032483514
-
Protein kinase G mediates vascular endothelial growth factor-induced Raf-1 activation and proliferation in human endothelial cells
-
J. Hood, and H.J. Granger Protein kinase G mediates vascular endothelial growth factor-induced Raf-1 activation and proliferation in human endothelial cells J. Biol. Chem. 273 1998 23504 23508
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 23504-23508
-
-
Hood, J.1
Granger, H.J.2
-
108
-
-
0033607756
-
Activation of mitogen-activated protein kinase pathways by cyclic GMP and cyclic GMP-dependent protein kinase in contractile vascular smooth muscle cells
-
P. Komalavilas, P.K. Shah, H. Jo, and T.M. Lincoln Activation of mitogen-activated protein kinase pathways by cyclic GMP and cyclic GMP-dependent protein kinase in contractile vascular smooth muscle cells J. Biol. Chem. 274 1999 34301 34309
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 34301-34309
-
-
Komalavilas, P.1
Shah, P.K.2
Jo, H.3
Lincoln, T.M.4
-
109
-
-
0344823963
-
A proatherogenic role for cGMP-dependent protein kinase in vascular smooth muscle cells
-
W. Wolfsgruber, S. Feil, S. Brummer, O. Kuppinger, F. Hofmann, and R. Feil A proatherogenic role for cGMP-dependent protein kinase in vascular smooth muscle cells Proc. Natl Acad. Sci. USA 100 2003 13519 13524
-
(2003)
Proc. Natl Acad. Sci. USA
, vol.100
, pp. 13519-13524
-
-
Wolfsgruber, W.1
Feil, S.2
Brummer, S.3
Kuppinger, O.4
Hofmann, F.5
Feil, R.6
-
110
-
-
0036784336
-
Activation of the mitogen activated protein kinase extracellular signal-regulated kinase 1 and 2 by the nitric oxide-cGMP-cGMP-dependent protein kinase axis regulates the expression of matrix metalloproteinase 13 in vascular endothelial cells
-
C. Zaragoza, E. Soria, E. Lopez, D. Browning, M. Balbin, C. Lopez-Otin, and S. Lamas Activation of the mitogen activated protein kinase extracellular signal-regulated kinase 1 and 2 by the nitric oxide-cGMP-cGMP-dependent protein kinase axis regulates the expression of matrix metalloproteinase 13 in vascular endothelial cells Mol. Pharmacol. 62 2002 927 935
-
(2002)
Mol. Pharmacol.
, vol.62
, pp. 927-935
-
-
Zaragoza, C.1
Soria, E.2
Lopez, E.3
Browning, D.4
Balbin, M.5
Lopez-Otin, C.6
Lamas, S.7
-
111
-
-
0036190203
-
Nitric oxide regulates matrix metalloprotease-13 expression and activity in endothelium
-
C. Zaragoza, M. Balbin, C. Lopez-Otin, and S. Lamas Nitric oxide regulates matrix metalloprotease-13 expression and activity in endothelium Kidney Int. 61 2002 804 808
-
(2002)
Kidney Int.
, vol.61
, pp. 804-808
-
-
Zaragoza, C.1
Balbin, M.2
Lopez-Otin, C.3
Lamas, S.4
-
112
-
-
0034810237
-
CGMP-dependent protein kinase phosphorylates and inactivates RhoA
-
N. Sawada, H. Itoh, J. Yamashita, K. Doi, M. Inoue, and K. Masatsugu cGMP-dependent protein kinase phosphorylates and inactivates RhoA Biochem. Biophys. Res. Commun. 280 2001 798 805
-
(2001)
Biochem. Biophys. Res. Commun.
, vol.280
, pp. 798-805
-
-
Sawada, N.1
Itoh, H.2
Yamashita, J.3
Doi, K.4
Inoue, M.5
Masatsugu, K.6
-
113
-
-
0037571979
-
Inhibition of sustained smooth muscle contraction by PKA and PKG preferentially mediated by phosphorylation of RhoA
-
K.S. Murthy, H. Zhou, J.R. Grider, and G.M. Makhlouf Inhibition of sustained smooth muscle contraction by PKA and PKG preferentially mediated by phosphorylation of RhoA Am. J. Physiol. Gastrointest. Liver Physiol. 284 2003 G1006 G1016
-
(2003)
Am. J. Physiol. Gastrointest. Liver Physiol.
, vol.284
-
-
Murthy, K.S.1
Zhou, H.2
Grider, J.R.3
Makhlouf, G.M.4
-
114
-
-
0038660670
-
RhoA expression is controlled by nitric oxide through cGMP-dependent protein kinase activation
-
V. Sauzeau, M. Rolli-Derkinderen, C. Marionneau, G. Loirand, and P. Pacaud RhoA expression is controlled by nitric oxide through cGMP-dependent protein kinase activation J. Biol. Chem. 278 2003 9472 9480
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 9472-9480
-
-
Sauzeau, V.1
Rolli-Derkinderen, M.2
Marionneau, C.3
Loirand, G.4
Pacaud, P.5
-
115
-
-
0037020262
-
CGMP-dependent protein kinase inhibits serum-response element-dependent transcription by inhibiting rho activation and functions
-
T. Gudi, J.C. Chen, D.E. Casteel, T.M. Seasholtz, G.R. Boss, and R.B. Pilz cGMP-dependent protein kinase inhibits serum-response element-dependent transcription by inhibiting rho activation and functions J. Biol. Chem. 277 2002 37382 37393
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 37382-37393
-
-
Gudi, T.1
Chen, J.C.2
Casteel, D.E.3
Seasholtz, T.M.4
Boss, G.R.5
Pilz, R.B.6
-
116
-
-
0037048683
-
The vasodilator-stimulated phosphoprotein promotes actin polymerisation through direct binding to monomeric actin
-
B. Walders-Harbeck, S.Y. Khaitlina, H. Hinssen, B.M. Jockusch, and S. Illenberger The vasodilator-stimulated phosphoprotein promotes actin polymerisation through direct binding to monomeric actin Fed. Eur. Biol. Soc. Lett. 529 2002 275 280
-
(2002)
Fed. Eur. Biol. Soc. Lett.
, vol.529
, pp. 275-280
-
-
Walders-Harbeck, B.1
Khaitlina, S.Y.2
Hinssen, H.3
Jockusch, B.M.4
Illenberger, S.5
-
117
-
-
0034613254
-
Phosphorylation of the vasodilator-stimulated phosphoprotein regulates its interaction with actin
-
B. Harbeck, S. Huttelmaier, K. Schluter, B.M. Jockusch, and S. Illenberger Phosphorylation of the vasodilator-stimulated phosphoprotein regulates its interaction with actin J. Biol. Chem. 275 2000 30817 30825
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 30817-30825
-
-
Harbeck, B.1
Huttelmaier, S.2
Schluter, K.3
Jockusch, B.M.4
Illenberger, S.5
-
118
-
-
0345687479
-
Ena/VASP proteins: Regulators of the actin cytoskeleton and cell migration
-
M. Krause, E.W. Dent, J.E. Bear, J.J. Loureiro, and F.B. Gertler Ena/VASP proteins: regulators of the actin cytoskeleton and cell migration Annu. Rev. Cell Dev. Biol. 19 2003 541 564
-
(2003)
Annu. Rev. Cell Dev. Biol.
, vol.19
, pp. 541-564
-
-
Krause, M.1
Dent, E.W.2
Bear, J.E.3
Loureiro, J.J.4
Gertler, F.B.5
-
119
-
-
0035312298
-
Actin-based motility: Stop and go with Ena/VASP proteins
-
M. Reinhard, T. Jarchau, and U. Walter Actin-based motility: stop and go with Ena/VASP proteins Trends Biochem. Sci. 26 2001 243 249
-
(2001)
Trends Biochem. Sci.
, vol.26
, pp. 243-249
-
-
Reinhard, M.1
Jarchau, T.2
Walter, U.3
-
120
-
-
0027953816
-
Human cyclic GMP-dependent protein kinase I beta overexpression increases phosphorylation of an endogenous focal contact-associated vasodilator- stimulated phosphoprotein without altering the thrombin-evoked calcium response
-
M. Meinecke, J. Geiger, E. Butt, M. Sandberg, T. Jahnsen, and T. Chakraborty Human cyclic GMP-dependent protein kinase I beta overexpression increases phosphorylation of an endogenous focal contact-associated vasodilator-stimulated phosphoprotein without altering the thrombin-evoked calcium response Mol. Pharmacol. 46 1994 283 290
-
(1994)
Mol. Pharmacol.
, vol.46
, pp. 283-290
-
-
Meinecke, M.1
Geiger, J.2
Butt, E.3
Sandberg, M.4
Jahnsen, T.5
Chakraborty, T.6
-
121
-
-
0039207312
-
The vasodilator-stimulated phosphoprotein (VASP) is involved in cGMP- and cAMP-mediated inhibition of agonist-induced platelet aggregation, but is dispensable for smooth muscle function
-
A. Aszodi, A. Pfeifer, M. Ahmad, M. Glauner, X.H. Zhou, and L. Ny The vasodilator-stimulated phosphoprotein (VASP) is involved in cGMP- and cAMP-mediated inhibition of agonist-induced platelet aggregation, but is dispensable for smooth muscle function Eur. Mol. Biol. Org. J. 18 1999 37 48
-
(1999)
Eur. Mol. Biol. Org. J.
, vol.18
, pp. 37-48
-
-
Aszodi, A.1
Pfeifer, A.2
Ahmad, M.3
Glauner, M.4
Zhou, X.H.5
Ny, L.6
-
122
-
-
0034682801
-
Regulation of human endothelial cell focal adhesion sites and migration by cGMP-dependent protein kinase I
-
A. Smolenski, W. Poller, U. Walter, and S.M. Lohmann Regulation of human endothelial cell focal adhesion sites and migration by cGMP-dependent protein kinase I J. Biol. Chem. 275 2000 25723 25732
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 25723-25732
-
-
Smolenski, A.1
Poller, W.2
Walter, U.3
Lohmann, S.M.4
-
123
-
-
0035887313
-
A WASp-VASP complex regulates actin polymerization at the plasma membrane
-
F. Castellano, C. Le Clainche, D. Patin, M.F. Carlier, and P. Chavrier A WASp-VASP complex regulates actin polymerization at the plasma membrane Eur. Mol. Biol. Org. J. 20 2001 5603 5614
-
(2001)
Eur. Mol. Biol. Org. J.
, vol.20
, pp. 5603-5614
-
-
Castellano, F.1
Le Clainche, C.2
Patin, D.3
Carlier, M.F.4
Chavrier, P.5
-
124
-
-
0037160086
-
Increased spreading, Rac/p21-activated kinase (PAK) activity, and compromised cell motility in cells deficient in vasodilator-stimulated phosphoprotein (VASP)
-
M.I. Garcia Arguinzonis, A.B. Galler, U. Walter, M. Reinhard, and A. Simm Increased spreading, Rac/p21-activated kinase (PAK) activity, and compromised cell motility in cells deficient in vasodilator-stimulated phosphoprotein (VASP) J. Biol. Chem. 277 2002 45604 45610
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 45604-45610
-
-
Garcia Arguinzonis, M.I.1
Galler, A.B.2
Walter, U.3
Reinhard, M.4
Simm, A.5
|