p21-activated kinase 1 (PAK1) interacts with the Grb2 adapter protein to couple to growth factor signaling

Journal of Biological Chemistry

Volumn 278, Issue 11, 2003, Pages 9388-9393

  Puto, Lorena A ^c   Pestonjamasp, Kersi ^c   King, Charles C ^a   Bokoch, Gary M ^b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b SCRIPPS RESEARCH INSTITUTE   (United States)

^c NONE

Author keywords

[No Author keywords available]

Indexed keywords

CELLS; POLYPEPTIDES; SIGNALING;

HOMOLOGY;

ENZYMES;

EPIDERMAL GROWTH FACTOR RECEPTOR; GROWTH FACTOR; GROWTH FACTOR RECEPTOR BOUND PROTEIN 2; P21 ACTIVATED KINASE 1; PROLINE; PROTEIN; PROTEIN CDC42; PROTEIN KINASE; PROTEIN P21; PROTEIN SH2; PROTEIN SH3; PROTEIN TYROSINE KINASE; RAC PROTEIN; TRANSACTIVATOR PROTEIN; UNCLASSIFIED DRUG; GRB2 PROTEIN, HUMAN; GROWTH PROMOTOR; PEPTIDE; PROTEIN SERINE THREONINE KINASE; SIGNAL TRANSDUCING ADAPTOR PROTEIN; TYROSINE;

ARTICLE; BINDING SITE; CELL PROLIFERATION; CELL SURVIVAL; CONTROLLED STUDY; CYTOSKELETON; DYNAMICS; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; SEQUENCE HOMOLOGY; SIGNAL TRANSDUCTION; SRC HOMOLOGY DOMAIN; CELL CULTURE; CELL DIVISION; CELL MEMBRANE; CHEMISTRY; IMMUNOBLOTTING; LEUKEMIA CELL LINE; METABOLISM; PHOSPHORYLATION; PLASMID; PROTEIN BINDING; PROTEIN TERTIARY STRUCTURE; SERODIAGNOSIS; TIME;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; CELL DIVISION; CELL MEMBRANE; CELL SURVIVAL; CYTOSKELETON; GRB2 ADAPTOR PROTEIN; GROWTH SUBSTANCES; HUMANS; IMMUNOBLOTTING; JURKAT CELLS; PEPTIDES; PHOSPHORYLATION; PLASMIDS; PRECIPITIN TESTS; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; PROTEIN-SERINE-THREONINE KINASES; PROTEINS; RECEPTOR, EPIDERMAL GROWTH FACTOR; SIGNAL TRANSDUCTION; SRC HOMOLOGY DOMAINS; TIME FACTORS; TUMOR CELLS, CULTURED; TYROSINE;

EID: 0038660689     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M208414200     Document Type: Article

References (38)

1. Schlessinger, J. (2000) Cell 103, 211-225
2. Blume-Jensen, P., and Hunter, T. (2001) Nature 411, 355-365
3. Fantl, W. J., Escobedo, J. A., Martin, G. A., Turck, C. W., del Rosario, M., McCormick, F., and Williams, L. T. (1992) Cell 69, 413-423
4. Pawson, T., and Scott, J. D. (1997) Science 278, 2075-2080
5. Rudd, C. E. (1999) Cell 96, 5-8
6. Lowenstein, E. J., Daly, R. J., Batzer, A. G., Li, W., Margolis, B., Lammers, R., Ullrich, A., Skolnik, E. Y., Bar-Sagi, D., and Schlessinger, J. (1992) Cell 70, 431-442
7. Matuoka, K., Shibata, M., Yamakawa, A., and Takenawa, T. (1992) Proc. Natl. Acad. Sci. U. S. A. 89, 9015-9019
8. Oliver, J. P., Raabe, T., Henkemeyer, M., Dickson, B., Mbamalu, G., Margolis, B., Schlessinger, Hafen, E., and Pawson, T. (1993) Cell 73, 179-191
9. Egan, S. E., Giddings B. W., Brooks, M. W., Buday, L., Sizeland, A. M., and Weinberg, R. A. (1993) Nature 363, 45-51
10. Knaus, U. G., and Bokoch, G. M. (1998) Int. Biochem. Cell Biol. 30, 857-862
11. Sells, M. A., and Chernoff, J. (1997) Trends Cell Biol. 7, 162-167
12. Manser, E., Leung, T., Salihuddin, H., Zhao, Z.-S., and Lim, L. (1994) Nature 367, 40-46
13. Bokoch, G. M., Reilly, A. M., Daniels, R. H., King, C. C., Olivera, A., Spiegel, S., and Knaus, U. G. (1998) J. Biol. Chem. 273, 8137-8144
14. Zenke, F. T., King, C. C., Bohl, B. P., and Bokoch, G. M. (1999) J. Biol. Chem. 274, 32565-32573
15. Lei, M., Lu, W., Meng, W., Parrini, M.-C., Eck, M., and Mayer, B. J. (2000) Cell 102, 387-397
16. Buchwald, G., Hostinova, E., Rudolph, M. G., Kraemer, A., Sickmann, A., Meyer, H. E., Scheffzek, K., and Wittinghofer, A. (2001) Mol. Cell. Biol. 21, 5179-5189
17. Daniels, R. H., and Bokoch, G. M. (1999) Trends Biochem. Sci. 24, 350-355
18. Edwards, D. C., Sanders, L. C., Bokoch, G. M., and Gill, G. N. (1999) Nat. Cell Biol. 1, 253-259
19. Tang, Y., Chen, Z., Ambrose, D., Liu, J., Gibbs, J. B., Chernoff, J., and Field, J. (1997) Mol. Cell. Biol. 17, 4454-4464
20. Chaudhary, A., King, W. G., Mattaliano, M. D., Frost, J. A., Diaz, B., Morrison, D. K., Cobb, M. H., Marshall, M. S., and Brugge, J. S. (2000) Curr. Biol. 10, 551-554
21. Maser, E., Loo, T. H., Koh, C. G., Zhao, Z. S., Chen, X. Q., Tan, L., Tan, I., Leung, T., and Lim, L. (1998) Mol. Cell. 1, 183-192
22. Galisteo, M. L., Chernoff, J., Su, Y. C., Skolnik, E. Y., and Schlessinger, J. (1996) J. Biol. Chem. 271, 20997-21000
23. Bokoch, G. M., Wang, Y., Bohl, B. P., Sells, M. A., Quilliam, L. A., and Knaus, U. G. (1996) J. Biol. Chem. 271, 25746-25749
24. Howe, A. K. (2001) J. Biol. Sci. 276, 14541-14544
25. Chong, C., Tan, L., Lim, L., and Manser, E. (2001) J. Biol. Chem. 276, 17347-17353
26. Yablonski, D., Kane, L. P., Qian, D., and Weiss, A. (1998) EMBO J. 17, 5647-5657
27. Izadi, K. D., Erdreich-Epstein, A., Liu, Y., and Durden, D. L. (1998) Exp. Cell Res. 245, 330-342
28. Price, L. S., Leng, J., Schwartz, M. A., and Bokoch, G. M. (1998) Mol. Biol. Cell 9, 1863-1871
29. Yu, H., Chen, J. K., Feng, S., Dalgarno, D. C., Brauer, A. W., and Schreiber, S. L. (1994) Cell 76, 933-945
30. Ho, A., Schwarze, S. R., Mermelstein, S. J., Waksman, G., and Dowdy, S. F. (2001) Cancer Res. 61, 474-477
31. Knaus, U. G., Morris, S., Dong, H.-J., Chernoff, J., and Bokoch, G. M. (1995) Science 269, 221-223
32. Yaffe, M. B., Leparc, G. G., Lai, J., Obata, S., Volinia, S., and Cantley, L. C. (2001) Nat. Biotechnol. 19, 348-353
33. Lu, W., Katz, S., Gupta, R., and Mayer, B. J. (1997) Curr. Biol. 7, 85-94
34. Tsakiridis, T., Taha, C., Grinstein, S., and Klip, A. (1996) J. Biol. Chem. 271, 19664-19667
35. Zhang, S., Han, J., Sells, M. A., Chernoff, J., Knaus, U. G., Ulevitch R. J., and Bokoch, G. M. (1995) J. Biol. Chem. 270, 23934-23936
36. Schurmann, A., Mooney, A. F., Sanders, L. C., Sells, M. A., Wang, H. G., Reed, J. C., and Bokoch, G. M. (2000) Mol. Biol. Cell 20, 453-461
37. Kiosses, W. B., Hood, J., Jang, S., Gerritsen, M. E., Cheresh, D. A., Alderson, N., and Schwartz, M. A. (2002) Circ. Res. 90, 697-702
38. Zhao, Z.-S., Manser, E., and Lim, L. (2000) Mol. Biol. Cell 20, 3906-3917