Calcium-activated RAF/MEK/ERK signaling pathway mediates p53-dependent apoptosis and is abrogated by αB-crystallin through inhibition of RAS activation

Molecular Biology of the Cell

Volumn 16, Issue 9, 2005, Pages 4437-4453

  Li, David Wan Cheng ^a,b,c   Liu, Jin Ping ^a   Mao, Ying Wei ^b,e   Xiang, Hua ^b,f   Wang, Juan ^b,g   Ma, Wei Ya ^a   Dong, Zigang ^a   Pike, Helen M ^a   Brown, Rhoderick E ^a   Reed, John C ^d  

^a UNIVERSITY OF MINNESOTA   (United States)

^b UNIVERSITY OF MEDICINE AND DENTISTRY OF NEW JERSEY   (United States)

^c HUNAN NORMAL UNIVERSITY   (China)

^d BURNHAM INSTITUTE   (United States)

^e UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^f INSTITUTE OF MICROBIOLOGY   (China)

^g UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA CRYSTALLIN; CALCIMYCIN; CALCIUM; CASPASE 3; HEAT SHOCK PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; PROTEIN BAX; PROTEIN P53; RAS PROTEIN;

ANIMAL CELL; APOPTOSIS; ARTICLE; CALCIUM TRANSPORT; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME INHIBITION; ENZYME RELEASE; EPITHELIUM CELL; GENE OVEREXPRESSION; LENS EPITHELIUM; MITOCHONDRION; MOLECULAR MECHANICS; NONHUMAN; PRIORITY JOURNAL; PROTEIN FAMILY; PROTEIN FUNCTION; SIGNAL TRANSDUCTION; UPREGULATION;

ALPHA-CRYSTALLIN B CHAIN; ANIMALS; APOPTOSIS; BUTADIENES; CALCIMYCIN; CALCIUM SIGNALING; CASPASE 3; CASPASES; CELL LINE; CYTOCHROMES C; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; MAP KINASE KINASE KINASE 1; MAP KINASE KINASE KINASE 2; NITRILES; RABBITS; RAF KINASES; RAS PROTEINS; TUMOR SUPPRESSOR PROTEIN P53;

EID: 24344508124     PISSN: 10591524     EISSN: None     Source Type: Journal    
DOI: 10.1091/mbc.E05-01-0010     Document Type: Article

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