Differential abilities of the Raf family of protein kinases to abrogate cytokine dependency and prevent apoptosis in murine hematopoietic cells by a MEK1-dependent mechanism

Leukemia

Volumn 14, Issue 4, 2000, Pages 642-656

  Hoyle, P E ^a   Moye, P W ^a   Steelman, L S ^a   Blalock, W L ^a   Franklin, R A ^a   Pearce, M ^a   Cherwinski, H ^b   Bosch, E ^b,c   McMahon, M ^b,d   McCubrey, J A ^a  

^a EAST CAROLINA UNIVERSITY   (United States)

^b MERCK RESEARCH LABORATORIES   (United States)

^c Sentinel Biosciences   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Cytokines; Hematopoietic cells; Oncogenes; Raf; Signal transduction

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; ESTRADIOL; ESTROGEN RECEPTOR; MITOGEN ACTIVATED PROTEIN KINASE; PHENYLALANINE; RAF PROTEIN;

AMINO ACID SUBSTITUTION; ANIMAL CELL; APOPTOSIS; ARTICLE; ENZYME ACTIVITY; HEMATOPOIETIC CELL; MALIGNANT TRANSFORMATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN FAMILY; SITE DIRECTED MUTAGENESIS;

EID: 0034076367     PISSN: 08876924     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.leu.2401720     Document Type: Article

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