Hypoxia-induced dedifferentiation of tumor cells - A mechanism behind heterogeneity and aggressiveness of solid tumors

Seminars in Cell and Developmental Biology

Volumn 16, Issue 4-5, 2005, Pages 554-563

  Axelson, Håkan ^a   Fredlund, Erik ^a   Ovenberger, Marie ^a   Landberg, Göran ^a   Påhlman, Sven ^a  

^a LUND UNIVERSITY   (Sweden)

Author keywords

Breast carcinoma; Differentiation; HIF 1 ; HIF 2 ; Hypoxia; Neuroblastoma; Sympathetic nervous system

Indexed keywords

GLUCOSE; HYPOXIA INDUCIBLE FACTOR 1ALPHA; HYPOXIA INDUCIBLE FACTOR 2ALPHA; NOTCH RECEPTOR; TRANSCRIPTION FACTOR;

ADRENERGIC SYSTEM; BREAST CARCINOMA; CANCER LOCALIZATION; CELL ACTIVITY; CELL DIFFERENTIATION; CELL MATURATION; CONCENTRATION RESPONSE; GENETIC HETEROGENEITY; HYPOXIA; MOLECULAR DYNAMICS; NERVOUS SYSTEM DEVELOPMENT; NEUROBLASTOMA CELL; PHENOTYPE; PROTEIN STRUCTURE; REGULATORY MECHANISM; REVIEW; SIGNAL TRANSDUCTION; SOLID TUMOR; STEM CELL; TISSUE OXYGENATION; TUMOR CELL;

ORA;

EID: 24344440832     PISSN: 10849521     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.semcdb.2005.03.007     Document Type: Review

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