In vivo spontaneous neuronal to neuroendocrine lineage conversion in a subset of neuroblastomas

American Journal of Pathology

Volumn 150, Issue 1, 1997, Pages 107-117

  Gestblom, Carolina ^a   Hoehner, Jeff C ^b   Hedborg, Fredrik ^b   Sandstedt, Bengt ^c   Påhlman, Sven ^a  

^a LUND UNIVERSITY   (Sweden)

^b UPPSALA UNIVERSITY HOSPITAL   (Sweden)

^c KAROLINSKA INSTITUTE   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

CHROMOGRANIN A; CHROMOGRANIN B; CYCLINE; NEUROMODULIN; NEURON SPECIFIC ENOLASE; NEUROPEPTIDE Y; PROTEIN BCL 2; SOMATOMEDIN B; TYROSINE 3 MONOOXYGENASE;

ADRENERGIC SYSTEM; ARTICLE; CANCER STAGING; CELL DIFFERENTIATION; CELL PROLIFERATION; CONTROLLED STUDY; EMBRYO; FETUS; HUMAN; HUMAN TISSUE; IN SITU HYBRIDIZATION; MARKER GENE; NERVE CELL; NEUROBLASTOMA; NEUROSECRETORY CELL; NEWBORN; PRESCHOOL CHILD; PRIORITY JOURNAL;

CELL DIFFERENTIATION; CHILD, PRESCHOOL; FETUS; GANGLIONEUROMA; HUMANS; INFANT; INFANT, NEWBORN; NEUROBLASTOMA; NEURONAL PLASTICITY; NEURONS; NEUROSECRETORY SYSTEMS; PHENOTYPE; SYMPATHETIC NERVOUS SYSTEM;

EID: 0031022022     PISSN: 00029440     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (35)

1. Landis SC, Patterson PH: Neural crest cell lineages, Trends Neurosci 1981, 4:172-175
2. Le Douarin NM, Smith J: Development of the peripheral nervous system from the neural crest. Annu Rev Cell Biol 1988, 4:375-404
3. Doupe AJ, Landis SC, Patterson PH: Environmental influences in the development of neural crest derivatives: glucocorticoids, growth factors, and chromaffin cell plasticity. J Neurosci 1985, 5:2119-2142
4. Doupe AJ, Patterson PH, Landis SC: Small intensely fluorescent cells in culture: role of growth factors in their development and interconversions with other neural crest derivatives, J Neurosci 1985, 5:2143-2160
5. Unsicker K, Krisch B, Otten J, Thoenen H: Nerve growth factor-induced fiber outgrowth from isolated rat adrenal chromaffin cells: impairment by glucocorticoids. Proc Natl Acad Sci USA 1978, 75:3498-3502
6. Aloe L, Levi-Montalcini R: Nerve growth factor-induced transformation of immature chromaffin cells in vivo into sympathetic neurons: effects of antiserum to nerve growth factor, Proc Natl Acad Sci USA 1979, 76:1246-1250
7. Greene LA: Nerve growth factor prevents the death and stimulates the neuronal differentiation of clonal PC12 pheochromocytoma cells in serum-free medium. J Biol Chem 1978, 78:747-755
8. Mizrachi Y, Naranjo JB, Levi B, Pollard HB, Lelkes PI: PC12 cells differentiate into chromaffin cell-like phenotype in coculture with adrenal medullary endothelial cells. Proc Natl Acad Sci USA 1990, 87:6161-6165
9. Gaetano C, Matsumoto K, Thiele CJ: In vitro activation of distinct molecular and cellular phenotypes after induction of differentiation in a human neuroblastoma cell line. Cancer Res 1992, 52:4402-4407
10. Joshi VV, Silverman JF: Pathology of neuroblastic tumors. Semin Diagn Pathol 1994, 11:107-117
11. Cooper MJ, Hutchins GM, Cohen PS, Helman LJ, Men nie RJ, Israel MA: Human neuroblastoma tumor cell lines correspond to the arrested differentiation of chromaffin adrenal medullary neuroblasts. Cell Growth Differ 1990, 1:149-159
12. Hedborg F, Ohlsson R, Sandstedt B, Grimelius L, Hoehner JC, Påhlman S: IGF-2 expression is a marker for paraganglionic/SIF cell differentiation in neuroblastoma. Am J Pathol 1995, 146:833-847
13. Hoehner JC, Hedborg F, Jernberg Wiklund H, Olsen L, Påhlman S: Cellular death in neuroblastoma: In situ correlation of apoptosis and bcl-2 expression. Int J Cancer 1995, 62:19-24
14. Hoehner JC, Gestblom C, Hedborg F, Sandstedt B, Påhlman S: A developmental model of neuroblastoma: favourable prognosis tumors differentiate along an extra-adrenal chromaffin lineage. Lab Invest (in press)
15. Shimada H, Chatten J, Newton WA, Sachs N, Hamoudi AB, Chiba T, Marsden HB, Misugi K: Histopathologic prognostic factors in neuroblastoma tumors: definition of subtypes of ganglioneuroblastomas and an age-linked classification of neuroblastomas. J Clin Invest 1984, 73:405-416
16. Örtoft E, BJelfman C, Hedborg F, Grimelius L, Påhlman S: The expression profile of alternatively spliced neuronal c-src RNA distinguishes between human tumours of the sympatho-adrenal lineage. Int J Cancer 1995, 60:38-44
17. Hoehner JC, Olsen L, Sandstedt B, Kaplan R, Påhlman S: Association of neurotrophin receptor expression and differentiation in human neuroblastoma. Am J Pathol 1995, 147:102-113
18. Brodeur GM, Pritchard J, Berthold F, Carlsen NLT, Castel V, Castleberry RP, De Bernardi B, Evans A, Favrot M, Hedborg F, Kaneko M, Kemshead J, Lampert F, Lee REJ, Look AT, Pearson APJ, Philips T, Roald B, Sawada T, Seeger RC, Tsuchida YT, Vovete PA: Revisions of the international criteria for neuroblastoma diagnosis, staging, and response to treatment. J Clin Oncol 1993, 11:1466-1477
19. Pezzella F, Tse AGD, Cordell JL, Pulford KAF, Galter KC, Mason DY: Expression of the bcl-2 oncogene protein is not specific for the 14; 18 chromosomal translocation. Am J Pathol 1990, 137:225-232
20. Soler Federsppiel BS, Cras P, Gheuens J, Andries D, Lowenthal A: Human γγ-enolase: two-site immunoradiometric assay with a single monoclonal antibody. J Neurochem 1987, 48:22-28
21. Wasdeem NH, Lane DP: Monoclonal antibody analysis of the proliferating cell nuclear antigen (PCNA): structural conservation and detection of a nucleolar form. J Cell Sci 1990, 96:121-129
22. Rohrer H, Acheson AL, Thibault J, Thoenen H: Developmental potential of quail dorsal root ganglia cells analyzed in vitro and in vivo. J Neurosci 1986, 6:2616-2624
23. Ohlsson R, Holmgren L, Glaser A, Szpecht A, Pfeifer-Ohlsson S: Insulin-like growth factor 2 and short-range stimulation loops in control of human placental growth. EMBO J 1989, 8:1993-1999
24. Basi GS, Jacobson RD, Virag I, Schilling J, Skene JHP: Primary structure and transcriptional regulation of GAP-43, a protein associated with nerve growth. Cell 1987, 49:785-791
25. Cohen PS, Cooper MJ, Helman LJ, Thiele CJ, Seeger RC, Israel MA: Neuropeptide Y expression in the developing adrenal gland and in childhood neuroblastoma tumors. Cancer Res 1990, 50:6055-6061
26. Evans AE: Natural history of neuroblastoma. Advances in Neuroblastoma Research. Edited by AE Evans. New York, Raven Press, 1980, pp 3-12
27. Vaneslow J, Grabczyk E, Ping J, Baetscher M, Teng S, Fishman M: GAP-43 transgenic mice: dispersed genomic sequences confer a GAP-43-like expression pattern during development and regeneration. J Neurosci 1994, 12:499-510
28. Alien YS, Adrian JE, Allen JM, Tatemoto K, Crow TJ, Bloom SR, Polak J: Neuropeptide Y distribution in the rat brain. Science 1983, 221:877-879
29. Varndell IM, Polak JM, Alien JM, Terenghi G, Bloom SR: Neuropeptide tyrosine (NPY) immunoreactivity in norepinephrine-containing cells and nerves of the mammalian adrenal gland. Endocrinology 1984, 114:1460-1462
30. Garcia I, Martinou I, Yoshihide T, Martinou JC: Prevention of programmed cell death of sympathetic neurons by the bcl-2 proto-oncogene. Science 1993, 258:302-304
31. Anderson DJ: Cellular neoteny: a possible developmental basis for chromaffin cell plasticity. Trends Genet 1989, 5:174-178
32. Patterson PH: Control of cell fate in a vertebrate neurogenic lineage. Cell 1990, 62:1035-1038
33. Anderson DJ, Axel R: A bipotential neuroendocrine precursor whose choice of cell fate is determined by NGF and glucocorticoids. Cell 1986, 47:1079-1090
34. Seidl K, Unsicker K: The determination of the adrenal medullary cell fate during embryogenesis. Dev Biol 1989, 136:481-490
35. Wurtman RJ, Axelrod J: Control of enzymatic synthesis of adrenaline in the adrenal medulla by adrenal cortical steroids. J Biol Chem 1966, 241:2301-2304