-
2
-
-
0031000736
-
A novel bHLH-PAS factor with close sequence similarity to hypoxia-inducible factor 1alpha regulates the VEGF expression and is potentially involved in lung and vascular development
-
M. Ema, S. Taya, N. Yokotani, K. Sogawa, Y. Matsuda, and Y. Fujii-Kuriyama A novel bHLH-PAS factor with close sequence similarity to hypoxia-inducible factor 1alpha regulates the VEGF expression and is potentially involved in lung and vascular development Proc. Natl. Acad. Sci. U. S. A. 94 1997 4273 4278
-
(1997)
Proc. Natl. Acad. Sci. U. S. A.
, vol.94
, pp. 4273-4278
-
-
Ema, M.1
Taya, S.2
Yokotani, N.3
Sogawa, K.4
Matsuda, Y.5
Fujii-Kuriyama, Y.6
-
3
-
-
0031733828
-
Molecular characterization and chromosomal localization of a third alpha-class hypoxia inducible factor subunit, HIF3alpha
-
Y.Z. Gu, S.M. Moran, J.B. Hogenesch, L. Wartman, and C.A. Bradfield Molecular characterization and chromosomal localization of a third alpha-class hypoxia inducible factor subunit, HIF3alpha Gene Expression 7 1998 205 213
-
(1998)
Gene Expression
, vol.7
, pp. 205-213
-
-
Gu, Y.Z.1
Moran, S.M.2
Hogenesch, J.B.3
Wartman, L.4
Bradfield, C.A.5
-
4
-
-
0036359548
-
Hypoxia-A key regulatory factor in tumour growth
-
A.L. Harris Hypoxia-A key regulatory factor in tumour growth Nat. Rev., Cancer 2 2002 38 47
-
(2002)
Nat. Rev., Cancer
, vol.2
, pp. 38-47
-
-
Harris, A.L.1
-
5
-
-
0033405216
-
Egr-1 mediates transcriptional activation of IGF-II gene in response to hypoxia
-
S.K. Bae, M.H. Bae, M.Y. Ahn, M.J. Son, Y.M. Lee, M.K. Bae, O.H. Lee, B.C. Park, and K.W. Kim Egr-1 mediates transcriptional activation of IGF-II gene in response to hypoxia Cancer Res. 59 1999 5989 5994
-
(1999)
Cancer Res.
, vol.59
, pp. 5989-5994
-
-
Bae, S.K.1
Bae, M.H.2
Ahn, M.Y.3
Son, M.J.4
Lee, Y.M.5
Bae, M.K.6
Lee, O.H.7
Park, B.C.8
Kim, K.W.9
-
6
-
-
0033566693
-
Reciprocal positive regulation of hypoxia-inducible factor 1alpha and insulin-like growth factor 2
-
D. Feldser, F. Agani, N.V. Iyer, B. Pak, G. Ferreira, and G.L. Semenza Reciprocal positive regulation of hypoxia-inducible factor 1alpha and insulin-like growth factor 2 Cancer Res. 59 1999 3915 3918
-
(1999)
Cancer Res.
, vol.59
, pp. 3915-3918
-
-
Feldser, D.1
Agani, F.2
Iyer, N.V.3
Pak, B.4
Ferreira, G.5
Semenza, G.L.6
-
7
-
-
0032213236
-
The hypoxia-responsive transcription factor EPAS1 is essential for catecholamine homeostasis and protection against heart failure during embryonic development
-
H. Tian, R.E. Hammer, A.M. Matsumoto, D.W. Russell, and S.L. McKnight The hypoxia-responsive transcription factor EPAS1 is essential for catecholamine homeostasis and protection against heart failure during embryonic development Genes Dev. 12 1998 3320 3324
-
(1998)
Genes Dev.
, vol.12
, pp. 3320-3324
-
-
Tian, H.1
Hammer, R.E.2
Matsumoto, A.M.3
Russell, D.W.4
McKnight, S.L.5
-
8
-
-
0032100732
-
HIF-1 alpha is required for solid tumor formation and embryonic vascularization
-
H.E. Ryan, J. Lo, and R.S. Johnson HIF-1 alpha is required for solid tumor formation and embryonic vascularization EMBO J. 17 1998 3005 3015
-
(1998)
EMBO J.
, vol.17
, pp. 3005-3015
-
-
Ryan, H.E.1
Lo, J.2
Johnson, R.S.3
-
9
-
-
0032167784
-
The human hypoxia-inducible factor 1alpha gene: HIF1A structure and evolutionary conservation
-
N.V. Iyer, S.W. Leung, and G.L. Semenza The human hypoxia-inducible factor 1alpha gene: HIF1A structure and evolutionary conservation Genomics 52 1998 159 165
-
(1998)
Genomics
, vol.52
, pp. 159-165
-
-
Iyer, N.V.1
Leung, S.W.2
Semenza, G.L.3
-
10
-
-
0034682513
-
The transcription factor EPAS-1/hypoxia-inducible factor 2alpha plays an important role in vascular remodeling
-
J. Peng, L. Zhang, L. Drysdale, and G.H. Fong The transcription factor EPAS-1/hypoxia-inducible factor 2alpha plays an important role in vascular remodeling Proc. Natl. Acad. Sci. U. S. A. 97 2000 8386 8391
-
(2000)
Proc. Natl. Acad. Sci. U. S. A.
, vol.97
, pp. 8386-8391
-
-
Peng, J.1
Zhang, L.2
Drysdale, L.3
Fong, G.H.4
-
11
-
-
0344826529
-
Multiple organ pathology, metabolic abnormalities and impaired homeostasis of reactive oxygen species in Epas1-/- mice
-
M. Scortegagna, K. Ding, Y. Oktay, A. Gaur, F. Thurmond, L.J. Yan, B.T. Marck, A.M. Matsumoto, J.M. Shelton, J.A. Richardson, M.J. Bennett, and J.A. Garcia Multiple organ pathology, metabolic abnormalities and impaired homeostasis of reactive oxygen species in Epas1-/- mice Nat. Genet. 35 2003 331 340
-
(2003)
Nat. Genet.
, vol.35
, pp. 331-340
-
-
Scortegagna, M.1
Ding, K.2
Oktay, Y.3
Gaur, A.4
Thurmond, F.5
Yan, L.J.6
Marck, B.T.7
Matsumoto, A.M.8
Shelton, J.M.9
Richardson, J.A.10
Bennett, M.J.11
Garcia, J.A.12
-
12
-
-
0037076385
-
Hypoxia alters gene expression in human neuroblastoma cells toward an immature and neural crest-like phenotype
-
A. Jögi, I. Øra, H. Nilsson, Å. Lindeheim, Y. Makino, L. Poellinger, H. Axelson, and S. Påhlman Hypoxia alters gene expression in human neuroblastoma cells toward an immature and neural crest-like phenotype Proc. Natl. Acad. Sci. U. S. A. 99 2002 7021 7026
-
(2002)
Proc. Natl. Acad. Sci. U. S. A.
, vol.99
, pp. 7021-7026
-
-
Jögi, A.1
Øra, I.2
Nilsson, H.3
Lindeheim, Å.4
Makino, Y.5
Poellinger, L.6
Axelson, H.7
Påhlman, S.8
-
13
-
-
0002524903
-
Development of the Neural Crest and Sympathetic Nervous System
-
G.M. Brodeur T. Sawada Y. Tsuchida P.A. Voûte Elsevier Amsterdam
-
S. Påhlman, and F. Hedborg Development of the Neural Crest and Sympathetic Nervous System G.M. Brodeur T. Sawada Y. Tsuchida P.A. Voûte Neuroblastoma 2000 Elsevier Amsterdam
-
(2000)
Neuroblastoma
-
-
Påhlman, S.1
Hedborg, F.2
-
14
-
-
0029852033
-
A developmental model of neuroblastoma: Differentiating stroma-poor tumors' progress along an extra-adrenal chromaffin lineage
-
J.C. Hoehner, C. Gestblom, F. Hedborg, B. Sandstedt, L. Olsen, and S. Påhlman A developmental model of neuroblastoma: differentiating stroma-poor tumors' progress along an extra-adrenal chromaffin lineage Lab. Invest. 75 1996 659 675
-
(1996)
Lab. Invest.
, vol.75
, pp. 659-675
-
-
Hoehner, J.C.1
Gestblom, C.2
Hedborg, F.3
Sandstedt, B.4
Olsen, L.5
Påhlman, S.6
-
15
-
-
0035914436
-
Hypoxia-inducible factor-2alpha (HIF-2alpha) is involved in the apoptotic response to hypoglycemia but not to hypoxia
-
K. Brusselmans, F. Bono, P. Maxwell, Y. Dor, M. Dewerchin, D. Collen, J.M. Herbert, and P. Carmeliet Hypoxia-inducible factor-2alpha (HIF-2alpha) is involved in the apoptotic response to hypoglycemia but not to hypoxia J. Biol. Chem. 276 2001 39192 39196
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 39192-39196
-
-
Brusselmans, K.1
Bono, F.2
Maxwell, P.3
Dor, Y.4
Dewerchin, M.5
Collen, D.6
Herbert, J.M.7
Carmeliet, P.8
-
16
-
-
0345491599
-
Differential roles of hypoxia-inducible factor 1alpha (HIF-1alpha) and HIF-2alpha in hypoxic gene regulation
-
C.J. Hu, L.Y. Wang, L.A. Chodosh, B. Keith, and M.C. Simon Differential roles of hypoxia-inducible factor 1alpha (HIF-1alpha) and HIF-2alpha in hypoxic gene regulation Mol. Cell. Biol. 23 2003 9361 9374
-
(2003)
Mol. Cell. Biol.
, vol.23
, pp. 9361-9374
-
-
Hu, C.J.1
Wang, L.Y.2
Chodosh, L.A.3
Keith, B.4
Simon, M.C.5
-
17
-
-
0029042738
-
Transfection of TRK-A into human neuroblastoma cells restores their ability to differentiate in response to nerve growth factor
-
E. Lavenius, C. Gestblom, I. Johansson, E. Nanberg, and S. Påhlman Transfection of TRK-A into human neuroblastoma cells restores their ability to differentiate in response to nerve growth factor Cell Growth Differ. 6 1995 727 736
-
(1995)
Cell Growth Differ.
, vol.6
, pp. 727-736
-
-
Lavenius, E.1
Gestblom, C.2
Johansson, I.3
Nanberg, E.4
Påhlman, S.5
-
18
-
-
0037380791
-
Hypoxia promotes a dedifferentiated phenotype in ductal breast carcinoma in situ
-
K. Helczynska, Å. Kronblad, A. Jögi, E. Nilsson, S. Beckman, G. Landberg, and S. Påhlman Hypoxia promotes a dedifferentiated phenotype in ductal breast carcinoma in situ Cancer Res. 63 2003 1441 1444
-
(2003)
Cancer Res.
, vol.63
, pp. 1441-1444
-
-
Helczynska, K.1
Kronblad, Å.2
Jögi, A.3
Nilsson, E.4
Beckman, S.5
Landberg, G.6
Påhlman, S.7
-
19
-
-
0033870281
-
The expression and distribution of the hypoxia-inducible factors HIF-1alpha and HIF-2alpha in normal human tissues, cancers, and tumor-associated macrophages
-
K.L. Talks, H. Turley, K.C. Gatter, P.H. Maxwell, C.W. Pugh, P.J. Ratcliffe, and A.L. Harris The expression and distribution of the hypoxia-inducible factors HIF-1alpha and HIF-2alpha in normal human tissues, cancers, and tumor-associated macrophages Am. J. Pathol. 157 2000 411 421
-
(2000)
Am. J. Pathol.
, vol.157
, pp. 411-421
-
-
Talks, K.L.1
Turley, H.2
Gatter, K.C.3
Maxwell, P.H.4
Pugh, C.W.5
Ratcliffe, P.J.6
Harris, A.L.7
-
20
-
-
2442583335
-
Arsenic trioxide-induced death of neuroblastoma cells involves activation of Bax and does not require p53
-
J. Karlsson, I. Øra, I. Pörn-Ares, and S. Påhlman Arsenic trioxide-induced death of neuroblastoma cells involves activation of Bax and does not require p53 Clin. Cancer Res. 10 2004 3179 3188
-
(2004)
Clin. Cancer Res.
, vol.10
, pp. 3179-3188
-
-
Karlsson, J.1
Øra, I.2
Pörn-Ares, I.3
Påhlman, S.4
-
21
-
-
0036534582
-
Elimination of primer-dimer artifacts and genomic coamplification using a two-step SYBR green I real-time RT-PCR
-
J. Vandesompele, A. De Paepe, and F. Speleman Elimination of primer-dimer artifacts and genomic coamplification using a two-step SYBR green I real-time RT-PCR Anal. Biochem. 303 2002 95 98
-
(2002)
Anal. Biochem.
, vol.303
, pp. 95-98
-
-
Vandesompele, J.1
De Paepe, A.2
Speleman, F.3
-
22
-
-
0037129827
-
Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes
-
J. Vandesompele, K. De Preter, F. Pattyn, B. Poppe, N. Van Roy, A. De Paepe, and F. Speleman Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes Genome Biol. 3 2002 1 11 (RESEARCH0034)
-
(2002)
Genome Biol.
, vol.3
, pp. 1-11
-
-
Vandesompele, J.1
De Preter, K.2
Pattyn, F.3
Poppe, B.4
Van Roy, N.5
De Paepe, A.6
Speleman, F.7
-
24
-
-
0031022022
-
In vivo spontaneous neuronal to neuroendocrine lineage conversion in a subset of neuroblastomas
-
C. Gestblom, J.C. Hoehner, F. Hedborg, B. Sandstedt, and S. Påhlman In vivo spontaneous neuronal to neuroendocrine lineage conversion in a subset of neuroblastomas Am. J. Pathol. 150 1997 107 117
-
(1997)
Am. J. Pathol.
, vol.150
, pp. 107-117
-
-
Gestblom, C.1
Hoehner, J.C.2
Hedborg, F.3
Sandstedt, B.4
Påhlman, S.5
-
25
-
-
0028916699
-
IGF2 expression is a marker for paraganglionic/SIF cell differentiation in neuroblastoma
-
F. Hedborg, R. Ohlsson, B. Sandstedt, L. Grimelius, J.C. Hoehner, and S. Påhlman IGF2 expression is a marker for paraganglionic/SIF cell differentiation in neuroblastoma Am. J. Pathol. 146 1995 833 847
-
(1995)
Am. J. Pathol.
, vol.146
, pp. 833-847
-
-
Hedborg, F.1
Ohlsson, R.2
Sandstedt, B.3
Grimelius, L.4
Hoehner, J.C.5
Påhlman, S.6
-
26
-
-
0030974517
-
Spatial association of apoptosis-related gene expression and cellular death in clinical neuroblastoma
-
J.C. Hoehner, C. Gestblom, L. Olsen, and S. Påhlman Spatial association of apoptosis-related gene expression and cellular death in clinical neuroblastoma Br. J. Cancer 75 1997 1185 1194
-
(1997)
Br. J. Cancer
, vol.75
, pp. 1185-1194
-
-
Hoehner, J.C.1
Gestblom, C.2
Olsen, L.3
Påhlman, S.4
-
27
-
-
0038788826
-
Hypoxia-induced gene expression occurs solely through the action of hypoxia-inducible factor 1alpha (HIF-1alpha): Role of cytoplasmic trapping of HIF-2alpha
-
S.K. Park, A.M. Dadak, V.H. Haase, L. Fontana, A.J. Giaccia, and R.S. Johnson Hypoxia-induced gene expression occurs solely through the action of hypoxia-inducible factor 1alpha (HIF-1alpha): role of cytoplasmic trapping of HIF-2alpha Mol. Cell. Biol. 23 2003 4959 4971
-
(2003)
Mol. Cell. Biol.
, vol.23
, pp. 4959-4971
-
-
Park, S.K.1
Dadak, A.M.2
Haase, V.H.3
Fontana, L.4
Giaccia, A.J.5
Johnson, R.S.6
-
28
-
-
0025883971
-
Insulin-like growth factor I shifts from promoting cell division to potentiating maturation during neuronal differentiation
-
S. Påhlman, G. Meyerson, E. Lindgren, M. Schalling, and I. Johansson Insulin-like growth factor I shifts from promoting cell division to potentiating maturation during neuronal differentiation Proc. Natl. Acad. Sci. U. S. A. 88 1991 9994 9998
-
(1991)
Proc. Natl. Acad. Sci. U. S. A.
, vol.88
, pp. 9994-9998
-
-
Påhlman, S.1
Meyerson, G.2
Lindgren, E.3
Schalling, M.4
Johansson, I.5
-
29
-
-
0032581277
-
Role of HIF-1alpha in hypoxia-mediated apoptosis, cell proliferation and tumour angiogenesis
-
P. Carmeliet, Y. Dor, J.M. Herbert, D. Fukumura, K. Brusselmans, M. Dewerchin, M. Neeman, F. Bono, R. Abramovitch, P. Maxwell, C.J. Koch, P. Ratcliffe, L. Moons, R.K. Jain, D. Collen, E. Keshert, and E. Keshet Role of HIF-1alpha in hypoxia-mediated apoptosis, cell proliferation and tumour angiogenesis Nature 394 1998 485 490
-
(1998)
Nature
, vol.394
, pp. 485-490
-
-
Carmeliet, P.1
Dor, Y.2
Herbert, J.M.3
Fukumura, D.4
Brusselmans, K.5
Dewerchin, M.6
Neeman, M.7
Bono, F.8
Abramovitch, R.9
Maxwell, P.10
Koch, C.J.11
Ratcliffe, P.12
Moons, L.13
Jain, R.K.14
Collen, D.15
Keshert, E.16
Keshet, E.17
-
30
-
-
0141988698
-
Predominant role of hypoxia-inducible transcription factor (Hif)-1alpha versus Hif-2alpha in regulation of the transcriptional response to hypoxia
-
H.M. Sowter, R.R. Raval, J.W. Moore, P.J. Ratcliffe, and A.L. Harris Predominant role of hypoxia-inducible transcription factor (Hif)-1alpha versus Hif-2alpha in regulation of the transcriptional response to hypoxia Cancer Res. 63 2003 6130 6134
-
(2003)
Cancer Res.
, vol.63
, pp. 6130-6134
-
-
Sowter, H.M.1
Raval, R.R.2
Moore, J.W.3
Ratcliffe, P.J.4
Harris, A.L.5
-
31
-
-
0032964898
-
Inhibition of angiogenesis induces chromaffin differentiation and apoptosis in neuroblastoma
-
E. Wassberg, F. Hedborg, E. Skoldenberg, M. Stridsberg, and R. Christofferson Inhibition of angiogenesis induces chromaffin differentiation and apoptosis in neuroblastoma Am. J. Pathol. 154 1999 395 403
-
(1999)
Am. J. Pathol.
, vol.154
, pp. 395-403
-
-
Wassberg, E.1
Hedborg, F.2
Skoldenberg, E.3
Stridsberg, M.4
Christofferson, R.5
-
32
-
-
0037387731
-
Evidence for hypoxia-induced neuronal-to-chromaffin metaplasia in neuroblastoma
-
F. Hedborg, E. Ulleras, L. Grimelius, E. Wassberg, P.H. Maxwell, B. Hero, F. Berthold, F. Schilling, D. Harms, B. Sandstedt, and G. Franklin Evidence for hypoxia-induced neuronal-to-chromaffin metaplasia in neuroblastoma FASEB J. 17 2003 598 609
-
(2003)
FASEB J.
, vol.17
, pp. 598-609
-
-
Hedborg, F.1
Ulleras, E.2
Grimelius, L.3
Wassberg, E.4
Maxwell, P.H.5
Hero, B.6
Berthold, F.7
Schilling, F.8
Harms, D.9
Sandstedt, B.10
Franklin, G.11
-
33
-
-
0036493984
-
Relation of hypoxia-inducible factor-2 alpha (HIF-2 alpha) expression in tumor-infiltrative macrophages to tumor angiogenesis and the oxidative thymidine phosphorylase pathway in Human breast cancer
-
R.D. Leek, K.L. Talks, F. Pezzella, H. Turley, L. Campo, N.S. Brown, R. Bicknell, M. Taylor, K.C. Gatter, and A.L. Harris Relation of hypoxia-inducible factor-2 alpha (HIF-2 alpha) expression in tumor-infiltrative macrophages to tumor angiogenesis and the oxidative thymidine phosphorylase pathway in Human breast cancer Cancer Res. 62 2002 1326 1329
-
(2002)
Cancer Res.
, vol.62
, pp. 1326-1329
-
-
Leek, R.D.1
Talks, K.L.2
Pezzella, F.3
Turley, H.4
Campo, L.5
Brown, N.S.6
Bicknell, R.7
Taylor, M.8
Gatter, K.C.9
Harris, A.L.10
-
34
-
-
1842861743
-
Human neuroblastoma cells exposed to hypoxia: Induction of genes associated with growth, survival, and aggressive behaviour
-
A. Jögi, J. Vallon-Christersson, L. Holmquist, H. Axelson, Å. Borg, and S. Påhlman Human neuroblastoma cells exposed to hypoxia: induction of genes associated with growth, survival, and aggressive behaviour Exp. Cell Res. 295 2004 469 487
-
(2004)
Exp. Cell Res.
, vol.295
, pp. 469-487
-
-
Jögi, A.1
Vallon-Christersson, J.2
Holmquist, L.3
Axelson, H.4
Borg, Å.5
Påhlman, S.6
-
35
-
-
0043124314
-
Regional cyclin D1 overexpression or hypoxia correlate inversely with heterogeneous oestrogen receptor-alpha expression in human breast cancer
-
Å. Kronblad, K. Helczynska, N.H. Nielsen, E. Pählman, S. Emdin, S. Pählman, and G. Landberg Regional cyclin D1 overexpression or hypoxia correlate inversely with heterogeneous oestrogen receptor-alpha expression in human breast cancer In Vivo 17 2003 311 318
-
(2003)
In Vivo
, vol.17
, pp. 311-318
-
-
Kronblad, Å.1
Helczynska, K.2
Nielsen, N.H.3
Pählman, E.4
Emdin, S.5
Pählman, S.6
Landberg, G.7
|