Culture in reduced levels of oxygen promotes clonogenic sympathoadrenal differentiation by isolated neural crest stem cells

Journal of Neuroscience

Volumn 20, Issue 19, 2000, Pages 7370-7376

  Morrison, S J ^a   Csete, M ^a   Groves, A K ^a   Melega, W ^a   Wold, B ^a   Anderson, D J ^a  

^a CALIFORNIA INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

Autonomic differentiation; Cell fate determination; Dopamine; Hypoxia; Neural crest; Noradrenergic; Oxygen; Stem cell; Sympathetic neuron; Sympathoadrenal

Indexed keywords

BONE MORPHOGENETIC PROTEIN 2; DOPAMINE; DOPAMINE BETA MONOOXYGENASE; FORSKOLIN; NORADRENALIN; OXYGEN; TYROSINE 3 MONOOXYGENASE;

ADRENERGIC SYSTEM; ANIMAL CELL; ARTICLE; CATECHOLAMINERGIC SYSTEM; CELL SURVIVAL; CLONOGENESIS; CONCENTRATION RESPONSE; CONTROLLED STUDY; DOPAMINE RELEASE; EMBRYO; NERVE CELL CULTURE; NERVE CELL DIFFERENTIATION; NERVE CELL GROWTH; NEURAL CREST CELL; NONHUMAN; NORADRENALIN RELEASE; OXYGENATION; PRIORITY JOURNAL; RAT; SCIATIC NERVE;

EID: 0034307432     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/jneurosci.20-19-07370.2000     Document Type: Article

References (31)

1. Molecular control of cell fate in the neural crest: The sympathoadrenal lineage
2. Antibody markers identify a common progenitor to sympathetic neurons and chromaffin cells in vivo, and reveal the timing of commitment to neuronal differentiation in the sympathoadrenal lineage
3. Sympathetic neurons undergo a developmental switch in trophic dependence
4. Better cells for brain repair
5. The molecular basis of the hypoxia response pathway: Tumor hypoxia as a therapy target
6. Generation of monoclonal antibodies that bind preferentially to adrenal chromaffin cells and the cells of embryonic sympathetic ganglia
7. Regulation of tyrosine hydroxylase gene expression in the rat carotid body by hypoxia
8. Hypoxia increases the rate of transcription and stability of tyrosine hydroxylase mRNA in pheochromocytoma (PC12) cells
9. Environmental influences in the development of neural crest derivatives: Glucocorticoids, growth factors and chromaffin cell plasticity
10. Small intensely fluorescent (SIF) cells in culture: Role of glucocorticoids and growth factors in their development and phenotypic interconversions with other neural crest derivatives
11. Migrating neural crest cells in the trunk of the avian embryo are multipotent
12. Survival of implanted fetal dopamine cells and neurologic improvement 12 to 46 months after transplantation for Parkinson's disease
13. Transport of oxygen and carbon dioxide in the blood and body fluids
14. Birth-related up-regulation of mRNA encoding tyrosine hydroxylase, dopamine-beta-hydroxylase, neuropeptide tyrosine, and prepro-enkephalin in rat adrenal medulla is dependent on postnatal oxygenation
15. Schwann cells and their precursors emerge as major regulators of nerve development
16. Specification of neuro-transmitter identity by Phox2 proteins m neural crest stem cells
17. Recovery of chronic parkinsonian monkeys by auto-transplants of carotid body cell aggregates into putamen
18. Regulation of gene expression for tyrosine hydroxylase in oxygen sensitive cells by hypoxia
19. Prospective identification, isolation by flow cytometry, and in vivo self-renewal of multipotent mammalian neural crest stem cells
20. 2-responsive sequences on the tyrosine hydroxylase gene
21. Regulation of tyrosine hydroxylase mRNA stability by protein-binding, pyrimidine-rich sequence in the 3'-untranslated region
22. Involvement of bone morphogenetic protein-4 and bone morphogenetic protein-7 in the differentiation of the adrenergic phenotype in developing sympathetic neurons
23. Alternative neural crest cell fates are instructively promoted by TGFβ superfamily members
24. Isolation of a stem cell for neurons and glia from the mammalian neural crest
25. Transplantation of expanded mesencephalic precursors leads to recovery in parkinsonian rats
26. Enhanced proliferation, survival, and dopaminergic differentiation of CNS precursors in lowered oxygen
27. The hypoxia-responsive transcription factor EPAS1 is essential for catecholamine homeostasis and protection against heart failure during embryonic development
28. BMP-2 and BMP-4, but not BMP-6, increase the number of adrenergic cells which develop in quail trunk neural crest cultures
29. Number of adrenergic and islet-1 immunoreactive cells is increased in avian trunk neural crest cultures in the presence of human recombinant osteogenic protein-1
30. Neurotrophins regulate sequential changes in neurotrophin receptor expression by sympathetic neuroblasts
31. Somatic cell cloned transgenic bovine neurons for transplantation in parkinsonian rats