Single-molecule fluorescence detection in microfluidic channels-the Holy Grail in μtAS?

Analytical and Bioanalytical Chemistry

Volumn 382, Issue 8, 2005, Pages 1771-1782

  Dittrich, Petra S ^a   Manz, Andreas ^a  

^a LEIBNIZ INSTITUT FÜR ANALYTISCHE WISSENSCHAFTEN ISAS E V   (Germany)

Author keywords

Cytometry; Fluorescence spectroscopy; Lab on a chip; Microfluidics; Single molecule detection

Indexed keywords

BIOTECHNOLOGY; DNA; DRUG PRODUCTS; FLUIDICS; MOLECULAR DYNAMICS; SCREENING; SPECTROSCOPIC ANALYSIS;

CYTOMETRY; FLUORESCENCE SPECTROSCOPY; LAB-ON-A-CHIP; MICROFLUIDICS; SINGLE-MOLECULE DETECTION (SMD);

FLUORESCENCE;

FLOW CYTOMETRY; GENETIC PROCEDURES; METHODOLOGY; MICROFLUIDICS; REVIEW; SENSITIVITY AND SPECIFICITY; SPECTROFLUOROMETRY;

BIOSENSING TECHNIQUES; FLOW CYTOMETRY; MICROFLUIDICS; SENSITIVITY AND SPECIFICITY; SPECTROMETRY, FLUORESCENCE;

EID: 23944527036     PISSN: 16182642     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00216-005-3335-9     Document Type: Review

References (193)

1. Craighead HG (2000) Science 290:1532
2. Quake SR, Scherer A (2000) Science 290:1536
3. Ito T, Okazaki S (2000) Nature 406:1027
4. Manz A, Graber N, Widmer HM (1990) Sens Actuators B 1:244
5. Manz A, Becker H (1999) (eds) Micro-system technology in chemistry and life sciences. Springer, Berlin Heidelberg New York
6. Eijkel JCT, deMello AJ, Manz A (1999) In: Masuhara H, de Schryver FC (eds) Organic mesoscopic chemistry. IUPAC monograph, Blackwell Science, Oxford, p 185
7. Ramsey JM (1999) Nat Biotechnol 17:1061
8. Mitchell P (2001) Nat Biotechnol 19:717
9. Reyes DR, Iossifidis D, Auroux PA, Manz A (2002) Anal Chem 74:2623
10. Auroux PA, Iossifidis D, Reyes DR, Manz A (2002) Anal Chem 74:2637
11. Beebe DJ, Mensing GA, Walker GM (2002) Annu Rev Biomed Eng 4:261
12. Nguyen NT, Wereley ST (2002) Fundamentals and applications of microfluidics. Artech House, Norwood, MA
13. Weigl BH, Bardell RL, Cabrera CR (2003) Adv Drug Delivery Rev 55:349
14. Oosterbroek RE, van den Berg A (eds) (2003) Lab-on-a-chip. Elsevier, Amsterdam
15. Andersson H, van den Berg A (eds) (2004) Lab-on-chips for cellomics. Kluwer, Dordrecht
16. Vilkner T, Janasek D, Manz A (2004) Anal Chem 76:3373
17. Stone HA, Stroock AD, Ajdari A (2004) Annu Rev Fluid Mech 36:381
18. Lakowicz JR (1999) Principle of fluorescence spectroscopy. Kluwer, New York
19. Schwarz MA, Hauser PC (2001) Lab Chip 1:1
20. Kitamori T, Tokeshi M, Hibara A, Sato K (2004) Anal Chem 76:53A
21. de Mello AJ (2003) Lab Chip 3:29N
22. Keller RA, Ambrose WP, Arias AA, Cai H, Emory SR, Goodwin PM, Jett JH (2002) Anal Chem 74:316A
23. Hirschfeld T (1976) Appl Opt 15:2965
24. Moerner WE, Kador L (1989) Phys Rev Lett 62:2535
25. Orrit M, Bernard J (1990) Phys Rev Lett 65:2716
26. Plakhotnik T, Donley EA, Wild UP (1997) Annu Rev Phys Chem 48:181
27. Tamarat P, Maali A, Lounis B, Orrit M (2000) J Phys Chem A 104:1
28. Xie XS, Trautman JK (1998) Annu Rev Phys Chem 49:441
29. Ambrose WP, Goodwin PM, Jett JH, Van Orden A, Werner JH, Keller RA (1999) Chem Rev 99:2929
30. Weiss S (1999) Science 283:1676
31. Yeung ES (2004) Annu Rev Phys Chem 55:97
32. Dickson RM, Norris DJ, Tzeng YL, Moerner WE (1996) Science 274:966
33. Peterman EJG, Sosa H, Moerner WE (2004) Annu Rev Phys Chem 55:79
34. Schütz GJ, Schindler H (2002) In: Zander C, Enderlein J, Keller RA (eds) Single molecule detection in solution. Wiley-VCH, Berlin, p 231
35. Schwille P (2001) Cell Biochem Biophys 34:383
36. Ichinose J, Sako Y (2004) Trends Anal Chem 23:587
37. Michalet X, Pinaud FF, Bentolila LA, Tsay JM, Doose S, Li JJ, Sundaresan G, Wu AM, Gambhir SS, Weiss S (2005) Science 307:538
38. Nie S, Chiu DT, Zare RN (1994) Science 266:1018
39. Dickson RM, Cubitt AB, Tsien RY, Moerner WE (1997) Nature 388:355
40. Xue Q, Yeung ES (1995) Nature 373:681
41. Lu HP, Xun L, Xie XS (1998) Science 282:1877
42. Widengren J, Rigler R, Mets Ü(1994) J Fluoresc 4:255
43. Widengren J, Rigler R (1996) Bioimaging 4:149
44. Xu XH, Yeung ES (1997) Science 275:1106
45. Eggeling C, Widengren J, Rigler R, Seidel CAM (1998) Anal Chem 70:2651
46. Dittrich PS, Schwille P (2001) Appl Phys B 73:829
47. Levene MJ, Korlach J, Turner SW, Foquet M, Craighead HG, Webb WW (2003) Science 299:682
48. Foquet M, Korlach J, Zipfel WR, Webb WW, Craighead HG (2004) Anal Chem 76:1618
49. Whitten WB, Ramsay JM, Arnold S, Bronk BV (1991) Anal Chem 63:1027
50. Barnes MD, Ng KC, Whitten WB, Ramsey JM (1993) Anal Chem 65:2360
51. Lermer N, Barnes MD, Kung CY, Whitten WB, Ramsay JM (1997) Anal Chem 69:2115
52. Axelrod D (2001) J Biomed Opt 6:6
53. Williams RM, Piston DW, Webb WW (1994) FASEB J 8:804
54. Mertz J, Xu C, Webb WW (1995) Opt Lett 20:2532
55. Pawley JB (1995) (ed) Handbook of biological confocal microscopy. Plenum, New York
56. Shera EB, Seitzinger NK, Davis LM, Keller RA, Soper SA (1990) Chem Phys Lett 174:553
57. van Orden A, Machara NP, Goodwin PM, Keller RA (1998) Anal Chem 70:1444
58. Barnes MD, Whitten WB, Ramsey JM (1995) Anal Chem 67:418A
59. Dörre K, Stephan J, Eigen M (2001) Single Mol 2:165
60. Enderlein J, Robbing DL, Ambrose WP, Goodwin PM, Keller RA (1997) Bioimaging 5:88
61. Soper SA, Davis LM, Shera EB (1992) J Opt Soc Am B 9:1761
62. Fries JR, Brand L, Eggeling C, Köllner M, Seidel CAM (1998) J Phys Chem A 102:6601
63. Zander C, Drexhage KH, Han KT, Wolfrum J, Sauer M (1998) Chem Phys Lett 286:457
64. Chen Y, Müller JD, So PTC, Gratton E (1999) Biophys J 77:553
65. Ma Y, Shortreed MR, Yeung ES (2000) Anal Chem 72:4640
66. Perroud TD, Huang B, Wallace MI, Zare RN (2003) Chem Phys Chem 4:1121
67. Kapanidis AN, Lee NK, Laurence TA, Doose S, Margeat E, Weiss S (2004) Proc Natl Acad Sci USA 101:8936
68. Schwille P, Meyer-Almes FJ, Rigler R (1997) Biophysics J 72:1878
69. Koltermann A, Kettling U, Bieschke J, Winkler T, Eigen M (1998) Proc Natl Acad Sci USA 95:1421
70. Winkler T, Kettling U, Koltermann A, Eigen M (1999) Proc Natl Acad Sci USA 96:1375
71. Kask P, Palo K, Ullmann D, Gall K (1999) Proc Natl Acad Sci 24:13756
72. Ha T, Enderle T, Ogletree DF, Chemla DS, Selvin PR, Weiss S (1996) Proc Natl Acad Sci USA 93:6264
73. Deniz AA, Laurence TA, Dahan M, Chemla DS, Schulz PG, Weiss S (2001) Annu Rev Phys Chem 52:233
74. Berney C, Danuser G (2003) Biophys J 84:3992
75. Wabuyele MB, Farquar H, Stryjewski W, Hammer RP, Soper SA, Cheng YW, Barany F (2003) J Am Chem Soc 125:6937
76. Dovichi NJ, Martin JC, Jett JH, Keller RA (1983) Science 219:845
77. Dovichi NJ, Martin JC, Jett JH, Trkula M, Keller RA (1984) Anal Chem 56:348
78. Nguyen DC, Keller RA, Jett JH, Martin JC (1987) Anal Chem 59:2158
79. Fister JC, Jacobson SC, Davis LM, Ramsey JM (1998) Anal Chem 70:431
80. Lundqvist A, Chiu DT, Orwar O (2003) Electrophoresis 24:1737
81. Ros A, Hellmich W, Duong T, Anselmetti D (2004) J Biotechnol 112:65
82. Demas JN, Wu M, Goodwin PM, Affleck RL, Keller RA (1998) Appl Spectrosc 52:755
83. Brody JP, Yager P, Goldstein RE, Austin RH (1996) Biophys J 71:3430
84. Knight JB, Vishwanath A, Brody JP, Austin RH (1998) Phys Rev Lett 80:3863
85. Dittrich PS, Schwille P (2003) Anal Chem 75:5767
86. Schrum DP, Culbertson CT, Jacobson SC, Ramsey JM (1999) Anal Chem 71:4173
87. Sundararajan N, Pio MS, Lee LP, Berlin AA (2004) J Micromechan Systems 13:559
88. Yang R, Feeback DL, Wang W (2005) Sens Act A 118:259
89. Dörre K, Stephan J, Lapczyna M, Stuke M, Dunkel H, Eigen M (2001) J Biotechn 86:225
90. Santiago JG, Wereley ST, Meinhart CD, Beebe DJ, Adrian RJ (1998) Exp Fluids 25:316
91. Chen Z, Milner TE, Dave D, Nelson JS (1997) Opt Lett 22:64
92. Schrum KF, Lancaster JM, Johnston SE, Gilman SD (2000) Anal Chem 72:4317
93. Paul PH, Garguilo MG, Rakestraw DJ (1998) Anal Chem 70:2459
94. Shelby JP, Chiu DT (2003) Anal Chem 75:1387
95. Edel JB, deMello AJ (2003) Anal Sci 19:1065
96. Magde D, Elson EL, Webb WW (1972) Phys Rev Lett 29:705
97. Eigen M, Rigler R (1994) Proc Natl Acad Sci USA 91:5740
98. Maiti S, Haupts U, Webb WW (1997) Proc Natl Acad Sci USA 94:11753
99. Schwille P, Bieschke J, Oehlenschläger F (1997) Biophys Chem 66:211
100. van Orden A, Fogarty K, Jung J (2004) Appl Spectr 58:122A
101. Tjernberg LO, Pramanik A, Björling S, Thyberg P, Thyberg J, Nordsted C, Berndt KD, Terenius L, Rigler R (1998) Chem Biol 6:53
102. Berland KM, So PTC, Chen Y, Mantulin WW, Gratton E (1996) Biophys J 71:410
103. Magde D, Webb WW, Elson EL (1978) Biopolymers 17:361
104. Köhler RH, Schwille P, Webb WW (1998) J Cell Sci 113:3921
105. Stagi M, Dittrich PS, Frank N, Iliev AI, Schwille P, Neumann H (2005) J Neurosci 25:352
106. Brinkmeier M, Rigler R (1995) Exp Techn Phys 41:205
107. Gösch M, Blom H, Holm J, Heino T, Rigler R (2000) Anal Chem 72:3260
108. Kunst BH, Schots A, Visser AJWG (2002) Anal Chem 74:5350
109. Dittrich PS, Schwille P (2002) Anal Chem 74:4472
110. Dittrich PS, Müller B, Schwille P (2004) Phys Chem Chem Phys 6:4416
111. Brinkmeier M, Dörre K, Riebeseel K, Rigler R (1997) Biophys Chem 66:229
112. Brinkmeier M, Dörre K, Stephan J, Eigen M (1999) Anal Chem 71:609
113. van Orden A, Keller RA (1998) Anal Chem 70:4463
114. LeCaptain DJ, Michel MA, Van Orden A (2001) Analyst 126:1279
115. LeCaptain DJ, Van Orden A (2002) Anal Chem 74:1171
116. Fogarty K, Van Orden A (2003) Anal Chem 75:6634
117. Hartridge H, Roughton FJW (1923) Proc R Soc Lond Ser A 104:376
118. Shastry MCR, Luck SD, Roder H (1998) Biophys J 74:2714
119. Pabit SA, Hagen SJ (2002) Biophys J 83:2872
120. van Oijen AM, Blainey PC, Crampton DJ, Richardson CC, Ellenberger T, Xie XS (2003) Science 301:1235
121. Song H, Ismagilov RF (2003) J Am Soc 125:14613
122. Lipman EA, Schuler B, Bakajin O, Eaton WA (2003) Science 301:1233
123. Dittrich PS, Schwille P (2005) Biophys J (submitted)
124. Castro A, Fairfield FR, Shera EB (1993) Anal Chem 65:849
125. Goodwin PM, Johnson ME, Martin JC, Ambrose WP, Marrone BL, Jett JH, Keller RA (1993) Nucl Acids Res 21:803
126. van Orden A, Cai H, Goodwin PM, Keller RA (1999) Anal Chem 71:2108
127. Chou HP, Spence C, Scherer A, Quake S (1999) Proc Natl Acad Sci USA 96:11
128. Wabuyele MB, Ford SM, Stryjewski W, Barrow J, Soper SA (2001) Electrophoresis 22:3939
129. Foquet M, Korlach J, Zipfel W, Webb WW, Craighead HG (2002) Anal Chem 74:1415
130. Ferris MM, Habbersett RC, Wolinsky M, Jett JH, Yoshida TM, Keller RA (2004) Cytometry Part A 60A:41
131. Castro A, Shera EB (1995) Anal Chem 67:3181
132. Duong TT, Kim G, Ros R, Streek M, Schmid F, Brugger J, Anselmetti D, Ros A (2002) Microelectron Eng 67-68:905
133. Lee JY, Li HW, Yeung ES (2004) J Chromatogr A 1053:173
134. Duke TAJ, Austin RH (1998) Phys Rev Lett 80:1552
135. Huang LR, Cox EC, Austin RH, Sturm JC (2003) Anal Chem 75:6963
136. Dapprich J, Nicklaus N (1998) Bioimaging 6:25
137. Wuite GJL, Davenport RJ, Rappaport A, Bustamante C (2000) Biophys J 79:1155
138. Yamashita K, Yamaguchi Y, Miyazaki M, Nakamura H, Shimizu H, Maeda H (2004) Chem Lett 33:628
139. Dimalanta ET, Lim A, Runnheim R, Lamers C, Churas C, Forrest DK, dePablo JJ, Graham MD, Coppersmith SN, Goldstein S, Schwartz DC (2004) Anal Chem 76:5293
140. Tegenfeldt JO, Prinz C, Cao H, Huang RL, Austin RH, Chou SY, Cox EC, Strum JC (2004) Anal Bioanal Chem 378:1678
141. Campbell LC, Wilkinson MJ, Manz A, Camilleri P, Humphreys CJ (2004) Lab Chip 4:225
142. Bakajin OB, Duke TAJ, Chou CF, Chan SS, Austin RH Cox EC (1998) Phys Rev Lett 80:2737
143. Chou CF, Austin RH, Bakajin O, Tegenfeldt JO, Castelino JA, Chan SS, Cox EC, Craighead H, Darnton N, Duke T, Han J, Turner S (2000) Electrophoresis 21:81
144. Schäfer B, Germeinhardt H, Greulich KO (2001) Angew Chem Int Edit 40:4663
145. Chan EY, Goncalves NM, Haeusler RA, Hatch AJ, Larson JW, Maletta AM, Yantz GR, Carstea ED, Fuchs M, Wong GG, Gullans SR, Gilmanshin R (2004) Genome Res 14:1137
146. Jett JH, Keller RA, Martin JC, Marrone BL, Moyzis RK, Ratliff RL, Seitzinger NK, Shera EB, Stewart CC (1989) J Biomol Struc Dyn 7:301
147. Harding JD, Keller RA (1992) Trends Biotechn 10:55
148. Dörre K, Brakmann S, Brinkmeier M, Han KT, Riebeseel K, Schwille P, Stephan J, Wetzel T, Lapczyna M, Stuke M, Bader R, Hinz M, Seliger H, Holm J, Eigen M, Rigler R (1997) Bioimaging 5:139
149. Sauer M, Angerer B, Ankenbauer W, Földes-Papp Z, Göbel F, Han KT, Rigler R, Schulz A, Wolfrum J, Zander C (2001) J Biotechn 86:181
150. Werner JH, Cai H, Jett JH, Reha-Krantz L, Keller RA, Goodwin PM (2003) J Biotechn 102:1
151. Brakmann S, Löbermann S (2001) Angew Chem Int Edit 40:1427
152. Brakmann S, Löbermann S (2002) Angew Chem Int Edit 41:3215
153. Braslavsky I, Hebert B, Kartalov E, Quake SR (2003) Proc Natl Acad Sci USA 100:3960
154. Kartalov EP, Quake SR (2004) Nucl Acid Res 32:2873
155. Kettling U, Koltermann A, Eigen M (1999) Curr Top Microbiol Immunol 243:173
156. Yeung ES (2001) Chem Rec 1:123
157. Ibrahim SF, van den Engh G (2003) Curr Opin Biotechnol 14:5
158. Nolan JP, Sklar LA (1998) Nat Biotechnol 16:633
159. Georgiou G (2001) Adv Protein Chem 55:293
160. Visser AJWG, Kunst BH, Keller H, Schots A (2004) Curr Pharmaceut Biotechnol 5:173
161. Skinner GM, Visscher K (2004) Assay Drug Dev Techn 2:397
162. Cullen CJ, Wootton RCR, deMello AJ (2004) Curr Opin Drug Disc Dev 7:798
163. Wölcke J, Ullmann D (2001) Drug Disc Today 6:637
164. Sundberg SA (2000) Curr Opin Biotechn 11:47
165. Rondelez Y, Tresset G, Tabata KV, Arata H, Fujita H, Takeuchi S, Noji H (2005) Nat Biotechnol 23:361
166. Fu AY, Spence C, Scherer A, Arnold FH, Quake SR (1999) Nat Biotechnol 17:1109
167. Fu AY, Chou HP, Spence C, Arnold FH, Quake SR (2002) Anal Chem 74:2451
168. Wolff A, Perch-Nielsen IR, Larsen UD, Friis P, Goranovic G, Poulsen CR, Kutter JP, Telleman P (2003) Lab Chip 3:22
169. Johann R, Renaud P (2004) Electrophoresis 25:3720
170. Fiedler S, Shirley SG, Schnelle T, Fuhr G (1998) Anal Chem 70:1909
171. Wang MM, Tu E, Raymond DE, Yang JM, Zhang H, Hagen N, Dees B, Mercer EM, Forster AH, Kariv I, Marchand PJ, Butler WF (2005) Nat Biotechnol 23:83
172. Kunst BH, Schots A, Visser AJWG (2002) Rev Sci Inst 75:2892
173. Emmelkamp J, Wolber F, Andersson H, DaCosta RS, Wilson BC, Vermes I, Van den Berg A (2004) Electrophoresis 25:3740
174. Song H, Tice JD, Ismagilov RF (2003) Angew Chem Int Edit 42:768
175. Chiu DT, Wilson CF, Karlsson A, Danielsson A, Lundqvist A, Strömberg A, Ryttsen F, Davidson M, Nordholm S, Orwar O, Zare RN (1999) Chem Phys 247:133
176. Thorsen T, Roberts RW, Arnold FH, Quake SR (2001) Phys Rev Lett 86:4163
177. Link DR, Anna SL, Weitz DA, Stone HA (2004) Phys Rev Lett 92:054503
178. Tan YC, Fisher JS, Lee AI, Cristini V, Lee AP (2004) Lab Chip 4:292
179. Roach LS, Song H, Ismagilov RF (2005) Anal Chem 77:785
180. Zheng B, Tice JD, Ismagilov RF (2004) Adv Mater 16:1365
181. Tawfik DS, Griffith AD (1998) Nat Biotechnol 16:652
182. Dittrich PS, Jahnz M, Schwille P (2005) Chem Bio Chem 6:811-814
183. Chiu DT, Wilson CF, Ryttsen F, Strömberg A, Farre C, Karlsson A, Nordholm S, Gaggar A, Modi BP, Moscho A, Garza-Lopez RA, Orwar O, Zare RN (1999) Science 283:1892
184. Strömberg A, Karlsson A, Ryttsen F, Davidson M, Chiu DT, Orwar O (2001) Anal Chem 73:126
185. Karlsson R, Karlsson A, Orwar O (2003) J Am Chem Soc 125:8442
186. Karlsson M, Davidson M, Karlsson R, Karlsson A, Bergen-holtz J, Konkoli Z, Jesorka A, Lobovkina T, Hurtig J, Voinova M, Orwar O (2004) Annu Rev Phys Chem 55:613
187. Jahn A, Vreeland WN, Gaitan M, Locascio LE (2004) J Am Chem Soc 126:2674
188. Blom H, Johansson M, Hedman AS, Lundberg L, Hanning A, Hard S, Rigler R (2002) Appl Opt 41:3336
189. Jackson JC, Phelan D, Morrison AP, Redfern RM, Mathewson A (2003) Opt Eng 42:112
190. Mathies S, Müller F (2003) Nature 424:53
191. Kamholz AE (2003) Nature Mat 2:507
192. Kohl T, Heinze KG, Kuhlemann R, Koltermann A, Schwille P (2002) Proc Natl Acad Sci USA 99:12161
193. Gast FU, Dittrich PS, Schwille P, Weigel M, Mertig M, Opitz J, Queitsch U, Diez S, Lincoln B, Wottawah F, Schinkinger S, Guck J, Käs J, Smolinski J, Salchert K, Werner C, Duschl C, Jäger MS, Uhlig K, Geggier P, Howitz S (2005) Microfluidics Nanofluidics (accepted)