Single-molecule measurement of protein folding kinetics

Science

Volumn 301, Issue 5637, 2003, Pages 1233-1235

  Lipman, Everett A ^a,d   Schuler, Benjamin ^a,b   Bakajin, Olgica ^c   Eaton, William A ^a  

^a NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

^b UNIVERSITY OF POTSDAM   (Germany)

^c LAWRENCE LIVERMORE NATIONAL LABORATORY   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ENERGY TRANSFER; LAMINAR FLOW; MOLECULAR STRUCTURE; MOLECULES; OPTICAL SYSTEMS; RESONANCE;

NATIVE STRUCTURE;

PROTEINS;

PROTEIN;

ARTICLE; ENERGY TRANSFER; FLUORESCENCE; KINETICS; LAMINAR FLOW; MIXER; PRIORITY JOURNAL; PROTEIN FOLDING;

BACTERIAL PROTEINS; COLD; DIFFUSION; ENERGY TRANSFER; FLUORESCENCE; FLUORESCENCE RESONANCE ENERGY TRANSFER; KINETICS; MODELS, MOLECULAR; PROTEIN CONFORMATION; PROTEIN DENATURATION; PROTEIN FOLDING; THERMODYNAMICS; THERMOTOGA MARITIMA;

EID: 0041321045     PISSN: 00368075     EISSN: None     Source Type: Journal    
DOI: 10.1126/science.1085399     Document Type: Article

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24. We thank R. Austin for essential advice and encouragement, K. Schwab for help with microfabrication, and S. Hagen for suggestions regarding the flow system. B.S. was supported by an Emmy Noether fellowship from the Deutsche Forschungsgemeinschaft. O.B.'s work was performed under the auspices of the U.S. Department of Energy under contract no. W-7405-Eng-48 with funding from the Laboratory Directed Research and Development program.