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Volumn 11, Issue 1, 2000, Pages 47-53

High-throughput and ultra-high-throughput screening: Solution- and cell-based approaches

Author keywords

[No Author keywords available]

Indexed keywords

DRUG; REAGENT;

EID: 0033964118     PISSN: 09581669     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0958-1669(99)00051-8     Document Type: Review
Times cited : (381)

References (55)
  • 1
    • 0031873720 scopus 로고    scopus 로고
    • Miniaturization technologies in HTS: How fast, how small, how soon?
    • Burbaum J. Miniaturization technologies in HTS: how fast, how small, how soon? Drug Discov Today. 3:1998;313-322.
    • (1998) Drug Discov Today , vol.3 , pp. 313-322
    • Burbaum, J.1
  • 2
    • 0002646723 scopus 로고    scopus 로고
    • Challenges and opportunities in high throughput screening: Implications for new technologies
    • Major J. Challenges and opportunities in high throughput screening: implications for new technologies. J Biomol Screening. 3:1998;13-17.
    • (1998) J Biomol Screening , vol.3 , pp. 13-17
    • Major, J.1
  • 3
    • 0032873519 scopus 로고    scopus 로고
    • What is the future of high throughput screening?
    • Divers M. What is the future of high throughput screening? J Biomol Screening. 4:1999;177-178.
    • (1999) J Biomol Screening , vol.4 , pp. 177-178
    • Divers, M.1
  • 4
    • 0033029954 scopus 로고    scopus 로고
    • What is the future of high throughput screening?
    • Stahl W. What is the future of high throughput screening? J Biomol Screening. 4:1999;117-118.
    • (1999) J Biomol Screening , vol.4 , pp. 117-118
    • Stahl, W.1
  • 5
    • 0031603149 scopus 로고    scopus 로고
    • Novel screen methodologies for identification of new microbial metabolites with pharmacological activity
    • Hill D., Wrigley S., Nisbet L. Novel screen methodologies for identification of new microbial metabolites with pharmacological activity. Adv Biochem Eng Biotechnol. 59:1998;73-121.
    • (1998) Adv Biochem Eng Biotechnol , vol.59 , pp. 73-121
    • Hill, D.1    Wrigley, S.2    Nisbet, L.3
  • 6
    • 0032241658 scopus 로고    scopus 로고
    • Homogeneous pharmacologic and cell-based screens provide diverse strategies in drug discovery: Somatostatin antagonists as a case study
    • Zysk J., Baumbach W. Homogeneous pharmacologic and cell-based screens provide diverse strategies in drug discovery: somatostatin antagonists as a case study. Comb Chem High Throughput Screen. 1:1998;171-183.
    • (1998) Comb Chem High Throughput Screen , vol.1 , pp. 171-183
    • Zysk, J.1    Baumbach, W.2
  • 7
    • 0000877218 scopus 로고    scopus 로고
    • High throughput, mechanism-based screening techniques for discovering novel agrochemicals
    • Walsh J. High throughput, mechanism-based screening techniques for discovering novel agrochemicals. J Biomol Screening. 3:1998;175-181.
    • (1998) J Biomol Screening , vol.3 , pp. 175-181
    • Walsh, J.1
  • 8
    • 0032873519 scopus 로고    scopus 로고
    • What is the future of high throughput screening?
    • Major J. What is the future of high throughput screening? J Biomol Screening. 4:1999;119.
    • (1999) J Biomol Screening , vol.4 , pp. 119
    • Major, J.1
  • 9
    • 0024969084 scopus 로고
    • Scintillation proximity assay
    • Bosworth N., Towers P. Scintillation proximity assay. Nature. 341:1989;167-168.
    • (1989) Nature , vol.341 , pp. 167-168
    • Bosworth, N.1    Towers, P.2
  • 10
    • 0031244338 scopus 로고    scopus 로고
    • High-throughput screening: Advances in assay technologies
    • Sittampalam G., Kahl S., Janzen W. High-throughput screening: advances in assay technologies. Curr Opin Chem Biol. 1:1997;384-391.
    • (1997) Curr Opin Chem Biol , vol.1 , pp. 384-391
    • Sittampalam, G.1    Kahl, S.2    Janzen, W.3
  • 11
    • 0001446284 scopus 로고    scopus 로고
    • Development of nonseparation binding and functional assays for G protein-coupled receptors for high throughput screening: Pharmacological characterization of the immobilized CCR5 receptor on FlashPlate
    • Bosse R., Garlick R., Brown B., Menard L. Development of nonseparation binding and functional assays for G protein-coupled receptors for high throughput screening: pharmacological characterization of the immobilized CCR5 receptor on FlashPlate. J Biomol Screening. 3:1998;285-292.
    • (1998) J Biomol Screening , vol.3 , pp. 285-292
    • Bosse, R.1    Garlick, R.2    Brown, B.3    Menard, L.4
  • 12
    • 0032943217 scopus 로고    scopus 로고
    • High throughput scintillation proximity assay for the identification of FKBP-12 ligands
    • Graziani F., Aldegheri L., Terstappen G. High throughput scintillation proximity assay for the identification of FKBP-12 ligands. J Biomol Screening. 4:1999;3-7.
    • (1999) J Biomol Screening , vol.4 , pp. 3-7
    • Graziani, F.1    Aldegheri, L.2    Terstappen, G.3
  • 13
    • 0032949754 scopus 로고    scopus 로고
    • High throughput quantitation of cAMP production mediated by activation of seven transmembrane domain receptors
    • Kariv I., Stevens M., Behrens D., Oldenburg K. High throughput quantitation of cAMP production mediated by activation of seven transmembrane domain receptors. J Biomol Screening. 4:1999;27-32.
    • (1999) J Biomol Screening , vol.4 , pp. 27-32
    • Kariv, I.1    Stevens, M.2    Behrens, D.3    Oldenburg, K.4
  • 14
    • 0342696800 scopus 로고    scopus 로고
    • Synthesis coupled to scintillation proximity affinity screening
    • An interesting application of solid-phase synthesis and scintillation proximity techniques to carry out compound synthesis and screening in an integrated format.
    • Parandoosh Z., Knowles S., Xiao X., Zhao C., David G., Nova M. Synthesis coupled to scintillation proximity affinity screening. J Biomol Screening. 3:1998;293. An interesting application of solid-phase synthesis and scintillation proximity techniques to carry out compound synthesis and screening in an integrated format.
    • (1998) J Biomol Screening , vol.3 , pp. 293
    • Parandoosh, Z.1    Knowles, S.2    Xiao, X.3    Zhao, C.4    David, G.5    Nova, M.6
  • 15
    • 0017795758 scopus 로고
    • Fluorescence energy transfer as a spectroscopic ruler
    • Stryer L. Fluorescence energy transfer as a spectroscopic ruler. Annu Rev Biochem. 47:1978;819-846.
    • (1978) Annu Rev Biochem , vol.47 , pp. 819-846
    • Stryer, L.1
  • 16
    • 0033059112 scopus 로고    scopus 로고
    • Digital imaging as a detection method for a fluorescent protease assay in 96-well and miniaturized assay plate formats
    • Abriola L., Chin M., Fuerst P., Schweitzer R., Sills M. Digital imaging as a detection method for a fluorescent protease assay in 96-well and miniaturized assay plate formats. J Biomol Screening. 4:1999;121.
    • (1999) J Biomol Screening , vol.4 , pp. 121
    • Abriola, L.1    Chin, M.2    Fuerst, P.3    Schweitzer, R.4    Sills, M.5
  • 17
    • 0032993958 scopus 로고    scopus 로고
    • A high throughput assay of the hepatitis C virus nonstructural protein 3 serine proteinase
    • Kakiuchi N., Nishikawa S., Hattori M., Shimotohno K. A high throughput assay of the hepatitis C virus nonstructural protein 3 serine proteinase. J Virol Methods. 80:1999;77-84.
    • (1999) J Virol Methods , vol.80 , pp. 77-84
    • Kakiuchi, N.1    Nishikawa, S.2    Hattori, M.3    Shimotohno, K.4
  • 18
    • 0032946626 scopus 로고    scopus 로고
    • S′ subsite mapping of serine proteases based on fluorescence resonance energy transfer
    • A novel use of fluorescence resonance energy transfer for mapping the S′ subsite specificity of serine proteases.
    • Grahn S., Kurth T., Ullmann D., Jakubke H. S′ subsite mapping of serine proteases based on fluorescence resonance energy transfer. Biochim Biophys Acta. 1431:1999;329-337. A novel use of fluorescence resonance energy transfer for mapping the S′ subsite specificity of serine proteases.
    • (1999) Biochim Biophys Acta , vol.1431 , pp. 329-337
    • Grahn, S.1    Kurth, T.2    Ullmann, D.3    Jakubke, H.4
  • 19
    • 0033190776 scopus 로고    scopus 로고
    • Screening for oligonucleotide binding affinity by a convenient fluorescence competition assay
    • Harrison J., Liu X., Balasubramanian S. Screening for oligonucleotide binding affinity by a convenient fluorescence competition assay. Nucleic Acids Res. 27:1999;14.
    • (1999) Nucleic Acids Res , vol.27 , pp. 14
    • Harrison, J.1    Liu, X.2    Balasubramanian, S.3
  • 20
    • 0028934572 scopus 로고
    • Fluorescence anisotropy applied to biomolecular interactions
    • Jameson D., Sawyer W. Fluorescence anisotropy applied to biomolecular interactions. Methods Enzymol. 246:1995;283-300.
    • (1995) Methods Enzymol , vol.246 , pp. 283-300
    • Jameson, D.1    Sawyer, W.2
  • 21
    • 0032861406 scopus 로고    scopus 로고
    • Fluorescence polarization: An analytical tool for immunoassay and drug discovery
    • A review describing recent applications of fluorescence polarization to replace solid-phase assays in fields ranging from studies of enzyme-catalyzed hydrolysis and protein-protein interactions to DNA diagnostics to high-throughput screening for drug discovery.
    • Nasir M., Jolley M. Fluorescence polarization: an analytical tool for immunoassay and drug discovery. Comb Chem High Throughput Screen. 2:1999;177-190. A review describing recent applications of fluorescence polarization to replace solid-phase assays in fields ranging from studies of enzyme-catalyzed hydrolysis and protein-protein interactions to DNA diagnostics to high-throughput screening for drug discovery.
    • (1999) Comb Chem High Throughput Screen , vol.2 , pp. 177-190
    • Nasir, M.1    Jolley, M.2
  • 22
    • 0031762676 scopus 로고    scopus 로고
    • Rapid screening of environmental chemicals for estrogen receptor binding capacity
    • Bolger R., Wiese T., Ervin K., Nestich S., Checovich W. Rapid screening of environmental chemicals for estrogen receptor binding capacity. Environ Health Perspect. 106:1998;551-557.
    • (1998) Environ Health Perspect , vol.106 , pp. 551-557
    • Bolger, R.1    Wiese, T.2    Ervin, K.3    Nestich, S.4    Checovich, W.5
  • 23
    • 0032518347 scopus 로고    scopus 로고
    • A fluorescence polarization competition immunoassay for tyrosine kinases
    • Seethala R., Menzel R. A fluorescence polarization competition immunoassay for tyrosine kinases. Anal Biochem. 255:1998;257-262.
    • (1998) Anal Biochem , vol.255 , pp. 257-262
    • Seethala, R.1    Menzel, R.2
  • 24
    • 0029134581 scopus 로고
    • Probing molecular interactions with homogeneous techniques based on rare earth cryptates and fluorescence energy transfer
    • Mathis G. Probing molecular interactions with homogeneous techniques based on rare earth cryptates and fluorescence energy transfer. Clin Chem. 41:1995;1391-1397.
    • (1995) Clin Chem , vol.41 , pp. 1391-1397
    • Mathis, G.1
  • 25
    • 0032126178 scopus 로고    scopus 로고
    • Homogeneous time-resolved IL-2-IL-2R alpha assay using fluorescence resonance energy transfer
    • Stenroos K., Hurskainen P. Homogeneous time-resolved IL-2-IL-2R alpha assay using fluorescence resonance energy transfer. Cytokine. 10:1998;495-499.
    • (1998) Cytokine , vol.10 , pp. 495-499
    • Stenroos, K.1    Hurskainen, P.2
  • 26
    • 0031821433 scopus 로고    scopus 로고
    • Tyrosine kinase assays adapted to homogeneous time-resolved fluorescence
    • An excellent overview of homogenous tyrosine kinase assays using time-resolved fluorescence as the detection method.
    • Kolb A., Kaplita P., Hayes D., Park Y., Pernell C., Major J., Mathis G. Tyrosine kinase assays adapted to homogeneous time-resolved fluorescence. Drug Discov Today. 3:1998;333-342. An excellent overview of homogenous tyrosine kinase assays using time-resolved fluorescence as the detection method.
    • (1998) Drug Discov Today , vol.3 , pp. 333-342
    • Kolb, A.1    Kaplita, P.2    Hayes, D.3    Park, Y.4    Pernell, C.5    Major, J.6    Mathis, G.7
  • 27
    • 0032851857 scopus 로고    scopus 로고
    • A homogenous 384-well high throughput screen for novel tumor necrosis factor receptor: Ligand interactions using time resolved energy transfer
    • Moore K., Turconi S., Miles-Williams A., Djaballah H., Hurskainen P., Harrop J., Murray K., Pope A. A homogenous 384-well high throughput screen for novel tumor necrosis factor receptor: ligand interactions using time resolved energy transfer. J Biomol Screening. 4:1999;205-214.
    • (1999) J Biomol Screening , vol.4 , pp. 205-214
    • Moore, K.1    Turconi, S.2    Miles-Williams, A.3    Djaballah, H.4    Hurskainen, P.5    Harrop, J.6    Murray, K.7    Pope, A.8
  • 28
    • 0031727047 scopus 로고    scopus 로고
    • Fluorescence correlation spectroscopy: Lead discovery by miniaturized HTS
    • A review of fluorescence correlation tyrosine kinase assays using time-resolved fluorescence as the detection method.
    • Auer M., Moore K., Meyer-Almes F., Guenther R., Pope A., Stoeckli K. Fluorescence correlation spectroscopy: lead discovery by miniaturized HTS. Drug Discov Today. 3:1998;457-465. A review of fluorescence correlation tyrosine kinase assays using time-resolved fluorescence as the detection method.
    • (1998) Drug Discov Today , vol.3 , pp. 457-465
    • Auer, M.1    Moore, K.2    Meyer-Almes, F.3    Guenther, R.4    Pope, A.5    Stoeckli, K.6
  • 29
    • 0032539625 scopus 로고    scopus 로고
    • Rapid assay processing by integration of dual-color fluorescence cross-correlation spectroscopy: High throughput screening of enzyme activity
    • Koltermann A., Kettling U., Bieschke J., Winkler T., Eigen M. Rapid assay processing by integration of dual-color fluorescence cross-correlation spectroscopy: high throughput screening of enzyme activity. Proc Natl Acad Sci USA. 95:1999;1421-1426.
    • (1999) Proc Natl Acad Sci USA , vol.95 , pp. 1421-1426
    • Koltermann, A.1    Kettling, U.2    Bieschke, J.3    Winkler, T.4    Eigen, M.5
  • 30
    • 0033564495 scopus 로고    scopus 로고
    • Chemiluminescence and bioluminescence
    • Kricka L. Chemiluminescence and bioluminescence. Anal Chem. 71:1999;305R-308R.
    • (1999) Anal Chem , vol.71
    • Kricka, L.1
  • 32
    • 0032927649 scopus 로고    scopus 로고
    • A review of recent trends in analytical applications of electrogenerated chemiluminescence
    • Knight A. A review of recent trends in analytical applications of electrogenerated chemiluminescence. Anal Chem. 18:1999;47-62.
    • (1999) Anal Chem , vol.18 , pp. 47-62
    • Knight, A.1
  • 34
    • 0344222200 scopus 로고    scopus 로고
    • HTS approaches to voltage-gated ion channel drug discovery
    • A good overview of voltage-gated ion channel screening methods with 33 references.
    • Denyer J., Worley J., Cox B., Allenby G., Banks M. HTS approaches to voltage-gated ion channel drug discovery. Drug Discov Today. 3:1998;323-332. A good overview of voltage-gated ion channel screening methods with 33 references.
    • (1998) Drug Discov Today , vol.3 , pp. 323-332
    • Denyer, J.1    Worley, J.2    Cox, B.3    Allenby, G.4    Banks, M.5
  • 35
    • 0344500746 scopus 로고    scopus 로고
    • Cell based assays and instrumentation for screening ion-channel targets
    • A good overview of cell-based assay methods for screening against ion channel targets, with a description of recently developed FRET-based voltage sensor dyes.
    • Gonzales J., Oades K., Leychkis Y., Harootunian A., Negulescu P. Cell based assays and instrumentation for screening ion-channel targets. Drug Discov Today. 4:1999;431-439. A good overview of cell-based assay methods for screening against ion channel targets, with a description of recently developed FRET-based voltage sensor dyes.
    • (1999) Drug Discov Today , vol.4 , pp. 431-439
    • Gonzales, J.1    Oades, K.2    Leychkis, Y.3    Harootunian, A.4    Negulescu, P.5
  • 36
    • 0032502840 scopus 로고    scopus 로고
    • Genetic recombination as a reporter for screening steroid receptor agonists and antagonists
    • Dias J., Go N., Hart C., Mattheakis L. Genetic recombination as a reporter for screening steroid receptor agonists and antagonists. Anal Biochem. 258:1998;96-102.
    • (1998) Anal Biochem , vol.258 , pp. 96-102
    • Dias, J.1    Go, N.2    Hart, C.3    Mattheakis, L.4
  • 37
    • 0031667867 scopus 로고    scopus 로고
    • A novel approach for examining the anti-proliferative effect of protein kinase C inhibitors against human astrocytoma cells
    • Sharif T., Sharif M. A novel approach for examining the anti-proliferative effect of protein kinase C inhibitors against human astrocytoma cells. Int J Oncol. 13:1998;685-692.
    • (1998) Int J Oncol , vol.13 , pp. 685-692
    • Sharif, T.1    Sharif, M.2
  • 38
    • 0033074481 scopus 로고    scopus 로고
    • A high throughput system for the evaluation of protein kinase C inhibitors based on Elk1 transcriptional activation in human astrocytoma cells
    • Sharif T., Sharif M. A high throughput system for the evaluation of protein kinase C inhibitors based on Elk1 transcriptional activation in human astrocytoma cells. Int J Oncol. 14:1999;327-335.
    • (1999) Int J Oncol , vol.14 , pp. 327-335
    • Sharif, T.1    Sharif, M.2
  • 39
    • 0031922812 scopus 로고    scopus 로고
    • A dual-luciferase reporter system for studying recoding signals
    • Grentzmann G., Ingram J., Kelly P., Gesteland R., Atkins J. A dual-luciferase reporter system for studying recoding signals. RNA. 4:1998;479-486.
    • (1998) RNA , vol.4 , pp. 479-486
    • Grentzmann, G.1    Ingram, J.2    Kelly, P.3    Gesteland, R.4    Atkins, J.5
  • 43
    • 0033083487 scopus 로고    scopus 로고
    • A high throughput colorimetric cell proliferation assay for the identification of human cytomegalovirus inhibitors
    • Bedard J., May S., Barbeau D., Yuen L., Rando R., Bowlin T. A high throughput colorimetric cell proliferation assay for the identification of human cytomegalovirus inhibitors. Antiviral Res. 41:1999;35-43.
    • (1999) Antiviral Res , vol.41 , pp. 35-43
    • Bedard, J.1    May, S.2    Barbeau, D.3    Yuen, L.4    Rando, R.5    Bowlin, T.6
  • 44
    • 84992904572 scopus 로고    scopus 로고
    • Beyond the 96-well microplate: Instruments and assay methods for the 384-well format
    • Kolb A., Neumann K. Beyond the 96-well microplate: instruments and assay methods for the 384-well format. J Biomol Screening. 2:1997;103-109.
    • (1997) J Biomol Screening , vol.2 , pp. 103-109
    • Kolb, A.1    Neumann, K.2
  • 45
    • 0001336521 scopus 로고    scopus 로고
    • A 384-HTS for human Factor VIIa: Comparison with 96- And 864-well formats
    • Comley J., Binnie A., Bonk C., Houston J. A 384-HTS for human Factor VIIa: comparison with 96- and 864-well formats. J Biomol Screening. 2:1997;171-178.
    • (1997) J Biomol Screening , vol.2 , pp. 171-178
    • Comley, J.1    Binnie, A.2    Bonk, C.3    Houston, J.4
  • 46
    • 0033055583 scopus 로고    scopus 로고
    • Miniaturization of a mammalian cell-based assay: Luciferase reporter gene readout in a 3 microliter 1536-well plate
    • Maffia A., Kariv I., Oldenburg K. Miniaturization of a mammalian cell-based assay: luciferase reporter gene readout in a 3 microliter 1536-well plate. J Biomol Screening. 4:1999;137-142.
    • (1999) J Biomol Screening , vol.4 , pp. 137-142
    • Maffia, A.1    Kariv, I.2    Oldenburg, K.3
  • 48
    • 0001799374 scopus 로고    scopus 로고
    • Assay miniaturization for ultra-high throughput screening of combinatorial and discrete compound libraries: A 9600-well (0.2 microliter) assay system
    • Oldenburg K., Zhang J., Chen T., Maffia A., Blom K., Combs A., Chung T. Assay miniaturization for ultra-high throughput screening of combinatorial and discrete compound libraries: a 9600-well (0.2 microliter) assay system. J Biomol Screening. 3:1998;55-62.
    • (1998) J Biomol Screening , vol.3 , pp. 55-62
    • Oldenburg, K.1    Zhang, J.2    Chen, T.3    Maffia, A.4    Blom, K.5    Combs, A.6    Chung, T.7
  • 49
    • 0031081614 scopus 로고    scopus 로고
    • Microchip-based capillary electrophoresis for immunoassays: Analysis of monoclonal antibodies and theophylline
    • Chiem N., Harrison J. Microchip-based capillary electrophoresis for immunoassays: analysis of monoclonal antibodies and theophylline. Anal Chem. 69:1997;373-378.
    • (1997) Anal Chem , vol.69 , pp. 373-378
    • Chiem, N.1    Harrison, J.2
  • 50
    • 0031889106 scopus 로고    scopus 로고
    • Microchip systems for immunoassay: An interated immunoreactor with electrophoretic separation for serum theophylline determination
    • Demonstration of a microchip-based immunoassay and electrophoretic separation of the reaction products using monoclonal antibodies and theopylline.
    • Chiem N., Harrison J. Microchip systems for immunoassay: an interated immunoreactor with electrophoretic separation for serum theophylline determination. Can Clin Chem. 44:1998;591-598. Demonstration of a microchip-based immunoassay and electrophoretic separation of the reaction products using monoclonal antibodies and theopylline.
    • (1998) Can Clin Chem , vol.44 , pp. 591-598
    • Chiem, N.1    Harrison, J.2
  • 52
    • 0032738605 scopus 로고    scopus 로고
    • Microfluidic assays of acetylcholinesterase inhibitors
    • Demonstration of a low-throughput enzyme inhibition assay carried out in a microchip format.
    • Hadd A., Jacobson S., Ramsey J. Microfluidic assays of acetylcholinesterase inhibitors. Anal Chem. 71:1999;5206-5212. Demonstration of a low-throughput enzyme inhibition assay carried out in a microchip format.
    • (1999) Anal Chem , vol.71 , pp. 5206-5212
    • Hadd, A.1    Jacobson, S.2    Ramsey, J.3
  • 53
    • 0033566860 scopus 로고    scopus 로고
    • A microchip-based enzyme assay for protein kinase A
    • Demonstration of a fluorescence-based kinase assay carried out in a microchip format using electrophoretic separation of the reaction product from the fluorescently tagged substrate as the assay read-out.
    • Cohen C., Chin-Dixon E., Jeong S., Nikiforov T. A microchip-based enzyme assay for protein kinase A. Anal Biochem. 273:1999;89-97. Demonstration of a fluorescence-based kinase assay carried out in a microchip format using electrophoretic separation of the reaction product from the fluorescently tagged substrate as the assay read-out.
    • (1999) Anal Biochem , vol.273 , pp. 89-97
    • Cohen, C.1    Chin-Dixon, E.2    Jeong, S.3    Nikiforov, T.4
  • 54
    • 0031569477 scopus 로고    scopus 로고
    • Transport, manipulation, and reaction of biological cells on-chip using electrokinetic effects
    • Li P., Harrison J. Transport, manipulation, and reaction of biological cells on-chip using electrokinetic effects. Anal Chem. 69:1997;1564-1568.
    • (1997) Anal Chem , vol.69 , pp. 1564-1568
    • Li, P.1    Harrison, J.2
  • 55
    • 0030710885 scopus 로고    scopus 로고
    • Biological cell assays on an electrokinetic microchip
    • Piscataway, NJ: IEEE Press
    • Andersson P., Li P., Smith R., Szarka R., Harrison J. Biological cell assays on an electrokinetic microchip. Transducers '97, vol 2. 1997;1311-1314 IEEE Press, Piscataway, NJ.
    • (1997) Transducers '97, Vol 2 , pp. 1311-1314
    • Andersson, P.1    Li, P.2    Smith, R.3    Szarka, R.4    Harrison, J.5


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