-
1
-
-
0034654326
-
Activation of apoptosis pathways by anticancer treatment
-
Debatin K (2000) Activation of apoptosis pathways by anticancer treatment. Toxicol Lett. 112-113: 41-48
-
(2000)
Toxicol. Lett.
, vol.112-113
, pp. 41-48
-
-
Debatin, K.1
-
2
-
-
0035500410
-
Apoptosis and cancer chemotherapy
-
Makin G and Dive C (2001) Apoptosis and cancer chemotherapy. Trends Cell Biol. 11: S22-S26
-
(2001)
Trends Cell Biol.
, vol.11
-
-
Makin, G.1
Dive, C.2
-
3
-
-
2642689658
-
Proteases to die for
-
Cryns V and Yuan J (1998) Proteases to die for. Genes Dev. 12: 1551-1570
-
(1998)
Genes Dev.
, vol.12
, pp. 1551-1570
-
-
Cryns, V.1
Yuan, J.2
-
5
-
-
2942746419
-
Caspase activation: Revisiting the induced proximity model
-
Shi Y (2004) Caspase activation: revisiting the induced proximity model. Cell 117: 855-858
-
(2004)
Cell
, vol.117
, pp. 855-858
-
-
Shi, Y.1
-
7
-
-
3943071150
-
Cytochrome C-mediated apoptosis
-
Jiang X and Wang X (2004) Cytochrome C-mediated apoptosis. Annu. Rev. Biochem. 73: 87-106
-
(2004)
Annu. Rev. Biochem.
, vol.73
, pp. 87-106
-
-
Jiang, X.1
Wang, X.2
-
8
-
-
0142117313
-
The Bcl-2 family: Roles in cell survival and oncogenesis
-
Cory S, Huang DC and Adams JM (2003) The Bcl-2 family: roles in cell survival and oncogenesis. Oncogene 22: 8590-8607
-
(2003)
Oncogene
, vol.22
, pp. 8590-8607
-
-
Cory, S.1
Huang, D.C.2
Adams, J.M.3
-
9
-
-
0037427412
-
Mechanisms of cytochrome c release by proapoptotic BCL-2 family members
-
Scorrano L and Korsmeyer SJ (2003) Mechanisms of cytochrome c release by proapoptotic BCL-2 family members. Biochem. Biophys. Res. Commun. 304: 437-444
-
(2003)
Biochem. Biophys. Res. Commun.
, vol.304
, pp. 437-444
-
-
Scorrano, L.1
Korsmeyer, S.J.2
-
11
-
-
0037069929
-
Chemotherapy: Targeting the mitochondrial cell death pathway
-
Debatin KM, Poncet D and Kroemer G (2002) Chemotherapy: targeting the mitochondrial cell death pathway. Oncogene 21: 8786-8803
-
(2002)
Oncogene
, vol.21
, pp. 8786-8803
-
-
Debatin, K.M.1
Poncet, D.2
Kroemer, G.3
-
12
-
-
0032544449
-
Apaf1 (CED-4 homolog) regulates programmed cell death in mammalian development
-
Cecconi F, Alvarez-Bolado G, Meyer BI, Roth KA and Gruss P (1998) Apaf1 (CED-4 homolog) regulates programmed cell death in mammalian development. Cell 94: 727-733
-
(1998)
Cell
, vol.94
, pp. 727-733
-
-
Cecconi, F.1
Alvarez-Bolado, G.2
Meyer, B.I.3
Roth, K.A.4
Gruss, P.5
-
13
-
-
0032506136
-
Oncogene-dependent apoptosis is mediated by caspase-9
-
Fearnhead HO, Rodriguez J, Govek EE, Guo W, Kobayashi R, Hannon G and Lazebnik YA (1998) Oncogene-dependent apoptosis is mediated by caspase-9. Proc. Natl. Acad. Sci. USA 95: 13664-13669
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 13664-13669
-
-
Fearnhead, H.O.1
Rodriguez, J.2
Govek, E.E.3
Guo, W.4
Kobayashi, R.5
Hannon, G.6
Lazebnik, Y.A.7
-
14
-
-
0032493870
-
Differential requirement for caspase 9 in apoptotic pathways in vivo
-
Hakem R, Hakem A, Duncan GS, Henderson JT, Woo M, Soengas MS, Elia A, de la Pompa JL, Kagi D, Khoo W, Potter J, Yoshida R, Kaufman SA, Lowe SW, Penninger JM and Mak TW (1998) Differential requirement for caspase 9 in apoptotic pathways in vivo. Cell 7: 339-345
-
(1998)
Cell
, vol.7
, pp. 339-345
-
-
Hakem, R.1
Hakem, A.2
Duncan, G.S.3
Henderson, J.T.4
Woo, M.5
Soengas, M.S.6
Elia, A.7
de la Pompa, J.L.8
Kagi, D.9
Khoo, W.10
Potter, J.11
Yoshida, R.12
Kaufman, S.A.13
Lowe, S.W.14
Penninger, J.M.15
Mak, T.W.16
-
15
-
-
0037162833
-
Requirement for caspase-2 in stress-induced apoptosis before mitochondrial permeabilization
-
Lassus P, Opitz-Araya X and Lazebnik Y (2002) Requirement for caspase-2 in stress-induced apoptosis before mitochondrial permeabilization. Science 297: 1352-1354
-
(2002)
Science
, vol.297
, pp. 1352-1354
-
-
Lassus, P.1
Opitz-Araya, X.2
Lazebnik, Y.3
-
16
-
-
0033515883
-
Apaf-1 and caspase-9 in p53-dependent apoptosis and tumor inhibition
-
Soengas MS, Alarcon RM, Yoshida H, Giaccia AJ, Hakem R, Mak TW and Lowe SW (1999) Apaf-1 and caspase-9 in p53-dependent apoptosis and tumor inhibition. Science 284: 156-159
-
(1999)
Science
, vol.284
, pp. 156-159
-
-
Soengas, M.S.1
Alarcon, R.M.2
Yoshida, H.3
Giaccia, A.J.4
Hakem, R.5
Mak, T.W.6
Lowe, S.W.7
-
17
-
-
0032544564
-
Apaf1 is required for mitochondrial pathways of apoptosis and brain development
-
Yoshida H, Kong YY, Yoshida R, Elia AJ, Hakem A, Hakem R, Penninger JM and Mak TM (1998) Apaf1 is required for mitochondrial pathways of apoptosis and brain development. Cell 94: 739-750
-
(1998)
Cell
, vol.94
, pp. 739-750
-
-
Yoshida, H.1
Kong, Y.Y.2
Yoshida, R.3
Elia, A.J.4
Hakem, A.5
Hakem, R.6
Penninger, J.M.7
Mak, T.M.8
-
18
-
-
0038485588
-
Role of caspases, Bid, and p53 in the apoptotic response triggered by histone deacetylase inhibitors trichostatin-A (TSA) and suberoylanilide hydroxamic acid (SAHA)
-
Henderson C, Mizzau M, Paroni G, Maestro R, Schneider C and Brancolini C (2003) Role of caspases, Bid, and p53 in the apoptotic response triggered by histone deacetylase inhibitors trichostatin-A (TSA) and suberoylanilide hydroxamic acid (SAHA). J. Biol. Chem. 278: 12579-12589
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 12579-12589
-
-
Henderson, C.1
Mizzau, M.2
Paroni, G.3
Maestro, R.4
Schneider, C.5
Brancolini, C.6
-
20
-
-
0032189348
-
Proteasome inhibitors: Valuable new tools for cell biologists
-
Lee DH and Goldberg AL (1998) Proteasome inhibitors: valuable new tools for cell biologists. Trends Cell Biol. 8: 397-403
-
(1998)
Trends Cell Biol.
, vol.8
, pp. 397-403
-
-
Lee, D.H.1
Goldberg, A.L.2
-
21
-
-
3042687605
-
Apaf-1 and caspase-9 accelerate apoptosis, but do not determine whether factor-deprived or drug-treated cells die
-
Ekert PG, Read SH, Silke J, Marsden VS, Kaufmann H, Hawkins CJ, Gerl R, Kumar S and Vaux DL (2004) Apaf-1 and caspase-9 accelerate apoptosis, but do not determine whether factor-deprived or drug-treated cells die. J. Cell Biol. 165: 835-842
-
(2004)
J. Cell Biol.
, vol.165
, pp. 835-842
-
-
Ekert, P.G.1
Read, S.H.2
Silke, J.3
Marsden, V.S.4
Kaufmann, H.5
Hawkins, C.J.6
Gerl, R.7
Kumar, S.8
Vaux, D.L.9
-
22
-
-
3042592579
-
Bcl-2-regulated apoptosis and cytochrome c release can occur independently of both caspase-2 and caspase-9
-
Marsden VS, Ekert PG, Van Delft M, Vaux DL, Adams JM and Strasser A (2004) Bcl-2-regulated apoptosis and cytochrome c release can occur independently of both caspase-2 and caspase-9. J. Cell Biol. 165: 775-780
-
(2004)
J. Cell Biol.
, vol.165
, pp. 775-780
-
-
Marsden, V.S.1
Ekert, P.G.2
Van Delft, M.3
Vaux, D.L.4
Adams, J.M.5
Strasser, A.6
-
23
-
-
0037057629
-
Apoptosis initiated by Bcl-2-regulated caspase activation independently of the cytochrome c/Apaf-1/caspase-9 apoptosome
-
Marsden VS, O'Connor L, O'Reilly LA, Silke J, Metcalf D, Ekert PG, Huang DC, Cecconi F, Kuida K, Tomaselli KJ, Roy S, Nicholson DW, Vaux DL, Bouillet P, Adams JM and Strasser A (2002) Apoptosis initiated by Bcl-2-regulated caspase activation independently of the cytochrome c/Apaf-1/caspase-9 apoptosome. Nature 419: 634-637
-
(2002)
Nature
, vol.419
, pp. 634-637
-
-
Marsden, V.S.1
O'Connor, L.2
O'Reilly, L.A.3
Silke, J.4
Metcalf, D.5
Ekert, P.G.6
Huang, D.C.7
Cecconi, F.8
Kuida, K.9
Tomaselli, K.J.10
Roy, S.11
Nicholson, D.W.12
Vaux, D.L.13
Bouillet, P.14
Adams, J.M.15
Strasser, A.16
-
24
-
-
0035957653
-
Proapoptotic BAX and BAK: A requisite gateway to mitochondrial dysfunction and death
-
Wei MC, Zong WX, Cheng EH, Lindsten T, Panoutsakopoulou V, Ross AJ, Roth KA, MacGregor GR, Thompson CB and Korsmeyer SJ (2001) Proapoptotic BAX and BAK: a requisite gateway to mitochondrial dysfunction and death. Science 292: 727-730
-
(2001)
Science
, vol.292
, pp. 727-730
-
-
Wei, M.C.1
Zong, W.X.2
Cheng, E.H.3
Lindsten, T.4
Panoutsakopoulou, V.5
Ross, A.J.6
Roth, K.A.7
MacGregor, G.R.8
Thompson, C.B.9
Korsmeyer, S.J.10
-
26
-
-
0037879052
-
The mitochondrial membrane potential (deltapsi(m)) in apoptosis; an update
-
Ly JD, Grubb DR and Lawen A (2003) The mitochondrial membrane potential (deltapsi(m)) in apoptosis; an update. Apoptosis 8: 115-128
-
(2003)
Apoptosis
, vol.8
, pp. 115-128
-
-
Ly, J.D.1
Grubb, D.R.2
Lawen, A.3
-
27
-
-
0033605376
-
Mitochondrial depolarization accompanies cytochrome c release during apoptosis in PC6 cells
-
Heiskanen KM, Bhat MB, Wang HM, Ma J and Nieminen AL (1999) Mitochondrial depolarization accompanies cytochrome c release during apoptosis in PC6 cells. J. Biol. Chem. 26: 5654-5658
-
(1999)
J. Biol. Chem.
, vol.26
, pp. 5654-5658
-
-
Heiskanen, K.M.1
Bhat, M.B.2
Wang, H.M.3
Ma, J.4
Nieminen, A.L.5
-
28
-
-
2942581328
-
Disruption of mitochondrial function during apoptosis is mediated by caspase cleavage of the p75 subunit of complex I of the electron transport chain
-
Ricci JE, Munoz-Pinedo C, Fitzgerald P, Bailly-Maitre B, Perkins GA, Yadava N, Scheffler IE, Ellisman MH and Green DR (2004) Disruption of mitochondrial function during apoptosis is mediated by caspase cleavage of the p75 subunit of complex I of the electron transport chain. Cell 117: 773-786
-
(2004)
Cell
, vol.117
, pp. 773-786
-
-
Ricci, J.E.1
Munoz-Pinedo, C.2
Fitzgerald, P.3
Bailly-Maitre, B.4
Perkins, G.A.5
Yadava, N.6
Scheffler, I.E.7
Ellisman, M.H.8
Green, D.R.9
-
29
-
-
0033529712
-
Commitment to apoptosis by GD3 ganglioside depends on opening of the mitochondrial permeability transition pore
-
Scorrano L, Petronilli V, Di Lisa F and Bernardi P (1999) Commitment to apoptosis by GD3 ganglioside depends on opening of the mitochondrial permeability transition pore. J. Biol. Chem. 274: 22581-22585
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 22581-22585
-
-
Scorrano, L.1
Petronilli, V.2
Di Lisa, F.3
Bernardi, P.4
-
30
-
-
0037326590
-
Outer mitochondrial membrane permeabilization during apoptosis triggers caspase-independent mitochondrial and caspase-dependent plasma membrane potential depolarization: A single-cell analysis
-
Dussmann H, Rehm M, Kogel D and Prehn JH (2003) Outer mitochondrial membrane permeabilization during apoptosis triggers caspase-independent mitochondrial and caspase-dependent plasma membrane potential depolarization: a single-cell analysis. J. Cell Sci. 116: 525-536
-
(2003)
J. Cell Sci.
, vol.116
, pp. 525-536
-
-
Dussmann, H.1
Rehm, M.2
Kogel, D.3
Prehn, J.H.4
-
31
-
-
0141768255
-
Real-time single cell analysis of Smac/DIABLO release during apoptosis
-
Rehm M, Dussmann H and Prehn JH (2003) Real-time single cell analysis of Smac/DIABLO release during apoptosis. J. Cell Biol. 162: 1031-1043
-
(2003)
J. Cell Biol.
, vol.162
, pp. 1031-1043
-
-
Rehm, M.1
Dussmann, H.2
Prehn, J.H.3
-
32
-
-
0035897408
-
Cytochrome c maintains mitochondrial transmembrane potential and ATP generation after outer mitochondrial membrane permeabilization during the apoptotic process
-
Waterhouse NJ, JGoldstein JC, von Ahsen O, Schuler M, Newmeyer DD and Green DR (2001) Cytochrome c maintains mitochondrial transmembrane potential and ATP generation after outer mitochondrial membrane permeabilization during the apoptotic process. J. Cell Biol. 153: 319-328
-
(2001)
J. Cell Biol.
, vol.153
, pp. 319-328
-
-
Waterhouse, N.J.1
JGoldstein, J.C.2
von Ahsen, O.3
Schuler, M.4
Newmeyer, D.D.5
Green, D.R.6
-
33
-
-
4444329609
-
Apollon ubiquitinates SMAC and caspase-9, and has an essential cytoprotection function
-
Hao Y, Sekine K, Kawabata A, Nakamura H, Ishioka T, Ohata H, Katayama R, Hashimoto C, Zhang X, Noda T, Tsuruo T and Naito M (2004) Apollon ubiquitinates SMAC and caspase-9, and has an essential cytoprotection function. Nat. Cell Biol. 6: 849-860
-
(2004)
Nat. Cell Biol.
, vol.6
, pp. 849-860
-
-
Hao, Y.1
Sekine, K.2
Kawabata, A.3
Nakamura, H.4
Ishioka, T.5
Ohata, H.6
Katayama, R.7
Hashimoto, C.8
Zhang, X.9
Noda, T.10
Tsuruo, T.11
Naito, M.12
-
34
-
-
0037184113
-
Proteasome-mediated degradation of Smac during apoptosis: XIAP promotes Smac ubiquitination in vitro
-
MacFarlane M, Merrison W, Bratton SB and Cohen GM (2002) Proteasome-mediated degradation of Smac during apoptosis: XIAP promotes Smac ubiquitination in vitro. J. Biol. Chem. 277: 36611-36616
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 36611-36616
-
-
MacFarlane, M.1
Merrison, W.2
Bratton, S.B.3
Cohen, G.M.4
-
35
-
-
2942674780
-
Dual role of BRUCE as an antiapoptotic IAP and a chimeric E2/E3 ubiquitin ligase
-
Bartke T, Pohl C, Pyrowolakis G and Jentsch S (2004) Dual role of BRUCE as an antiapoptotic IAP and a chimeric E2/E3 ubiquitin ligase. Mol Cell 14: 801-811
-
(2004)
Mol. Cell
, vol.14
, pp. 801-811
-
-
Bartke, T.1
Pohl, C.2
Pyrowolakis, G.3
Jentsch, S.4
-
36
-
-
0037855783
-
Cellular inhibitor of apoptosis 1 and 2 are ubiquitin ligases for the apoptosis inducer Smac/DIABLO
-
Hu S and Yang X (2003) Cellular inhibitor of apoptosis 1 and 2 are ubiquitin ligases for the apoptosis inducer Smac/DIABLO. J. Biol. Chem. 278: 10055-10060
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 10055-10060
-
-
Hu, S.1
Yang, X.2
-
37
-
-
12844258128
-
The membrane-associated inhibitor of apoptosis protein, BRUCE/Apollon, antagonizes both the precursor and mature forms of Smac and caspase-9
-
Qiu XB and Goldberg AL (2005) The membrane-associated inhibitor of apoptosis protein, BRUCE/Apollon, antagonizes both the precursor and mature forms of Smac and caspase-9. J. Biol. Chem. 280: 174-182
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 174-182
-
-
Qiu, X.B.1
Goldberg, A.L.2
-
38
-
-
10944247878
-
Neutralization of Smac/Diablo by inhibitors of apoptosis (IAPs): A caspase-independent mechanism for apoptotic inhibition
-
Wilkinson JC, Wilkinson AS, Scott FL, Csomos RA, Salvesen GS and Duckett CS (2004) Neutralization of Smac/Diablo by inhibitors of apoptosis (IAPs): a caspase-independent mechanism for apoptotic inhibition. J. Biol. Chem. 279: 51082-51090
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 51082-51090
-
-
Wilkinson, J.C.1
Wilkinson, A.S.2
Scott, F.L.3
Csomos, R.A.4
Salvesen, G.S.5
Duckett, C.S.6
-
39
-
-
0037470027
-
A novel ubiquitin fusion system bypasses the mitochondria and generates biologically active Smac/DIABLO
-
Hunter AM, Kottachchi D, Lewis J, Duckett CS, Korneluk RG and Liston P (2003) A novel ubiquitin fusion system bypasses the mitochondria and generates biologically active Smac/DIABLO. J. Biol. Chem. 278: 7494-7499
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 7494-7499
-
-
Hunter, A.M.1
Kottachchi, D.2
Lewis, J.3
Duckett, C.S.4
Korneluk, R.G.5
Liston, P.6
-
40
-
-
0034710649
-
Structural and biochemical basis of apoptotic activation by Smac/DIABLO
-
Chai J, Du C, Wu JW, Kyin S, Wang X and Shi Y (2000) Structural and biochemical basis of apoptotic activation by Smac/DIABLO. Nature 406: 855-862
-
(2000)
Nature
, vol.406
, pp. 855-862
-
-
Chai, J.1
Du, C.2
Wu, J.W.3
Kyin, S.4
Wang, X.5
Shi, Y.6
-
41
-
-
0034680876
-
Molecular determinants of the caspase-promoting activity of Smac/DIABLO and its role in the death receptor pathway
-
Srinivasula SM, Datta P, Fan XJ, Fernandes-Alnemri F, Huang Z and Alnemri ES (2000) Molecular determinants of the caspase-promoting activity of Smac/DIABLO and its role in the death receptor pathway. J. Biol. Chem. 275: 36152-36157
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 36152-36157
-
-
Srinivasula, S.M.1
Datta, P.2
Fan, X.J.3
Fernandes-Alnemri, F.4
Huang, Z.5
Alnemri, E.S.6
-
42
-
-
0035282570
-
A conserved XIAP-interaction motif in caspase-9 and Smac/DIABLO regulates caspase activity and apoptosis
-
Srinivasula SM, Hegde R, Saleh A, Datta P, Shiozaki E, Chai J, Lee RA, Robbins PD, Fernandes-Alnemri T, Shi Y and Alnemri ES (2001) A conserved XIAP-interaction motif in caspase-9 and Smac/DIABLO regulates caspase activity and apoptosis. Nature 410: 112-116
-
(2001)
Nature
, vol.410
, pp. 112-116
-
-
Srinivasula, S.M.1
Hegde, R.2
Saleh, A.3
Datta, P.4
Shiozaki, E.5
Chai, J.6
Lee, R.A.7
Robbins, P.D.8
Fernandes-Alnemri, T.9
Shi, Y.10
Alnemri, E.S.11
-
43
-
-
0034700491
-
Structural basis of IAP recognition by Smac/DIABLO
-
Wu G, Chai J, Suber TL, Wu JW, Du C, Wang X and Shi Y (2000) Structural basis of IAP recognition by Smac/DIABLO. Nature 408: 1008-1012
-
(2000)
Nature
, vol.408
, pp. 1008-1012
-
-
Wu, G.1
Chai, J.2
Suber, T.L.3
Wu, J.W.4
Du, C.5
Wang, X.6
Shi, Y.7
-
44
-
-
1842472483
-
Caspase activation inhibits proteasome function during apoptosis
-
Sun XM, Butterworth M, MacFarlane M, Dubiel W, Ciechanover A and Cohen GM 2004 Caspase activation inhibits proteasome function during apoptosis. Mol. Cell. 14: 81-93
-
(2004)
Mol. Cell.
, vol.14
, pp. 81-93
-
-
Sun, X.M.1
Butterworth, M.2
MacFarlane, M.3
Dubiel, W.4
Ciechanover, A.5
Cohen, G.M.6
-
45
-
-
0036240701
-
The proteasome: A novel target for cancer chemotherapy
-
Almond JB and Cohen GM (2002) The proteasome: a novel target for cancer chemotherapy. Leukemia 16: 433-443
-
(2002)
Leukemia
, vol.16
, pp. 433-443
-
-
Almond, J.B.1
Cohen, G.M.2
-
46
-
-
2342613652
-
The proteasome: A suitable antineoplastic target
-
Adams J (2004) The proteasome: a suitable antineoplastic target. Nat. Rev. Cancer 4: 349-360
-
(2004)
Nat. Rev. Cancer
, vol.4
, pp. 349-360
-
-
Adams, J.1
-
47
-
-
0033152760
-
Proteasome inhibitors: A novel class of potent and effective antitumor agents
-
Adams J, Palombella VJ, Sausville EA, Johnson J, Destree A, Lazarus DD, Maas J, Pien CS, Prakash S and Elliott PJ (1999) Proteasome inhibitors: a novel class of potent and effective antitumor agents. Cancer Res. 59: 2615-2622
-
(1999)
Cancer Res.
, vol.59
, pp. 2615-2622
-
-
Adams, J.1
Palombella, V.J.2
Sausville, E.A.3
Johnson, J.4
Destree, A.5
Lazarus, D.D.6
Maas, J.7
Pien, C.S.8
Prakash, S.9
Elliott, P.J.10
-
48
-
-
0030962262
-
p53-dependent induction of apoptosis by proteasome inhibitors
-
Lopes UG, Erhardt P, Yao R and Cooper GM (1997) p53-dependent induction of apoptosis by proteasome inhibitors. J. Biol. Chem. 272: 12893-12896
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 12893-12896
-
-
Lopes, U.G.1
Erhardt, P.2
Yao, R.3
Cooper, G.M.4
-
49
-
-
0035284812
-
Proteasomes modulate balance among proapoptotic and antiapoptotic Bcl-2 family members and compromise functioning of the electron transport chain in leukemic cells
-
Marshansky V, Wang X, Bertrand R, Luo H, Duguid W, Chinnadurai G, Kanaan N, Vu N and Wu J (2001) Proteasomes modulate balance among proapoptotic and antiapoptotic Bcl-2 family members and compromise functioning of the electron transport chain in leukemic cells. J. Immunol. 166: 3130-3142
-
(2001)
J. Immunol.
, vol.166
, pp. 3130-3142
-
-
Marshansky, V.1
Wang, X.2
Bertrand, R.3
Luo, H.4
Duguid, W.5
Chinnadurai, G.6
Kanaan, N.7
Vu, N.8
Wu, J.9
-
50
-
-
0033773607
-
Proteasome inhibitor-induced apoptosis of glioma cells involves the processing of multiple caspases and cytochrome c release
-
Wagenknecht B, Hermisson M, Groscurth P, Liston P, Krammer PH and Weller M (2000) Proteasome inhibitor-induced apoptosis of glioma cells involves the processing of multiple caspases and cytochrome c release. J. Neurochem. 75: 2288-2297
-
(2000)
J. Neurochem.
, vol.75
, pp. 2288-2297
-
-
Wagenknecht, B.1
Hermisson, M.2
Groscurth, P.3
Liston, P.4
Krammer, P.H.5
Weller, M.6
-
51
-
-
0037516876
-
Conformational change and mitochondrial translocation of Bax accompany proteasome inhibitor-induced apoptosis of chronic lymphocytic leukemic cells
-
Dewson G, Snowden RT, Almond JB, Dyer MJ and Cohen GM (2003) Conformational change and mitochondrial translocation of Bax accompany proteasome inhibitor-induced apoptosis of chronic lymphocytic leukemic cells. Oncogene 22: 2643-2654
-
(2003)
Oncogene
, vol.22
, pp. 2643-2654
-
-
Dewson, G.1
Snowden, R.T.2
Almond, J.B.3
Dyer, M.J.4
Cohen, G.M.5
-
52
-
-
1642564603
-
Inhibition of proteasomal function by curcumin induces apoptosis through mitochondrial pathway
-
Jana NR, Dikshit P, Goswami A and Nukina N (2004) Inhibition of proteasomal function by curcumin induces apoptosis through mitochondrial pathway. J. Biol. Chem. 279: 11680-11685
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 11680-11685
-
-
Jana, N.R.1
Dikshit, P.2
Goswami, A.3
Nukina, N.4
-
53
-
-
0242496212
-
Molecular sequelae of proteasome inhibition in human multiple myeloma cells
-
Mitsiades N, Mitsiades CS, Poulaki V, Chauhan D, Fanourakis G, Gu X, Bailey C, Joseph M, Libermann TA, Treon SP, Munshi NC, Richardson PG, Hideshima T and Anderson KC (2002) Molecular sequelae of proteasome inhibition in human multiple myeloma cells. Proc. Natl. Acad. Sci. USA 99: 14374-14379
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 14374-14379
-
-
Mitsiades, N.1
Mitsiades, C.S.2
Poulaki, V.3
Chauhan, D.4
Fanourakis, G.5
Gu, X.6
Bailey, C.7
Joseph, M.8
Libermann, T.A.9
Treon, S.P.10
Munshi, N.C.11
Richardson, P.G.12
Hideshima, T.13
Anderson, K.C.14
-
54
-
-
7644242953
-
Proteasome inhibitor PS-341 induces apoptosis through induction of endoplasmic reticulum stress-reactive oxygen species in head and neck squamous cell carcinoma cells
-
Fribley A, Zeng Q and Wang CY (2004) Proteasome inhibitor PS-341 induces apoptosis through induction of endoplasmic reticulum stress-reactive oxygen species in head and neck squamous cell carcinoma cells. Mol. Cell Biol. 24: 9695-9704
-
(2004)
Mol. Cell Biol.
, vol.24
, pp. 9695-9704
-
-
Fribley, A.1
Zeng, Q.2
Wang, C.Y.3
-
55
-
-
0141706672
-
Reactive oxygen species generation and mitochondrial dysfunction in the apoptotic response to Bortezomib, a novel proteasome inhibitor, in human H460 non-small cell lung cancer cells
-
Ling YH, Liebes L, Zou Y and Perez-Soler R (2003) Reactive oxygen species generation and mitochondrial dysfunction in the apoptotic response to Bortezomib, a novel proteasome inhibitor, in human H460 non-small cell lung cancer cells. J. Biol. Chem. 278: 33714-33723
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 33714-33723
-
-
Ling, Y.H.1
Liebes, L.2
Zou, Y.3
Perez-Soler, R.4
-
56
-
-
2442645048
-
Proteasome inhibition alters neural mitochondrial homeostasis and mitochondria turnover
-
Sullivan PG, Dragicevic NB, Deng JH, Bai Y, Dimayuga E, Ding Q, Chen Q, Bruce-Keller AJ and Keller JN (2004) Proteasome inhibition alters neural mitochondrial homeostasis and mitochondria turnover. J. Biol. Chem. 279: 20699-20707
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 20699-20707
-
-
Sullivan, P.G.1
Dragicevic, N.B.2
Deng, J.H.3
Bai, Y.4
Dimayuga, E.5
Ding, Q.6
Chen, Q.7
Bruce-Keller, A.J.8
Keller, J.N.9
-
57
-
-
1842861723
-
The hierarchical relationship between MAPK signaling and ROS generation in human leukemia cells undergoing apoptosis in response to the proteasome inhibitor Bortezomib
-
Yu C, Rahmani M, Dent P and Grant S (2004) The hierarchical relationship between MAPK signaling and ROS generation in human leukemia cells undergoing apoptosis in response to the proteasome inhibitor Bortezomib. Exp. Cell Res. 295: 555-566
-
(2004)
Exp. Cell Res.
, vol.295
, pp. 555-566
-
-
Yu, C.1
Rahmani, M.2
Dent, P.3
Grant, S.4
-
58
-
-
0043170892
-
BCL6 overexpression prevents increase in reactive oxygen species and inhibits apoptosis induced by chemotherapeutic reagents in B-cell lymphoma cells
-
Kurosu T, Fukuda T, Miki T and Miura O (2003) BCL6 overexpression prevents increase in reactive oxygen species and inhibits apoptosis induced by chemotherapeutic reagents in B-cell lymphoma cells. Oncogene 22: 4459-4468
-
(2003)
Oncogene
, vol.22
, pp. 4459-4468
-
-
Kurosu, T.1
Fukuda, T.2
Miki, T.3
Miura, O.4
-
59
-
-
1942534018
-
Regulation of apoptosis proteins in cancer cells by ubiquitin
-
Zhang HG, Wang J, Yang X, Hsu HC and Mountz JD (2004) Regulation of apoptosis proteins in cancer cells by ubiquitin. Oncogene 23: 2009-2015
-
(2004)
Oncogene
, vol.23
, pp. 2009-2015
-
-
Zhang, H.G.1
Wang, J.2
Yang, X.3
Hsu, H.C.4
Mountz, J.D.5
-
60
-
-
9144234685
-
Small-molecule antagonists of apoptosis suppressor XIAP exhibit broad antitumor activity
-
Schimmer AD, Welsh K, Pinilla C, Wang Z, Krajewska M, Bonneau MJ, Pedersen IM, Kitada S, Scott FL, Bailly-Maitre B, Glinsky G, Scudiero D, Sausville E, Salvesen G, Nefzi A, Ostresh JM, Houghten RA and Reed JC (2004) Small-molecule antagonists of apoptosis suppressor XIAP exhibit broad antitumor activity. Cancer Cell 5: 25-35
-
(2004)
Cancer Cell
, vol.5
, pp. 25-35
-
-
Schimmer, A.D.1
Welsh, K.2
Pinilla, C.3
Wang, Z.4
Krajewska, M.5
Bonneau, M.J.6
Pedersen, I.M.7
Kitada, S.8
Scott, F.L.9
Bailly-Maitre, B.10
Glinsky, G.11
Scudiero, D.12
Sausville, E.13
Salvesen, G.14
Nefzi, A.15
Ostresh, J.M.16
Houghten, R.A.17
Reed, J.C.18
-
61
-
-
9144265592
-
Cellular, biochemical, and genetic analysis of mechanism of small molecule IAP inhibitors
-
Wang Z, Cuddy M, Samuel T, Welsh K, Schimmer A, Hanaii F, Houghten R, Pinilla C and Reed JC (2004) Cellular, biochemical, and genetic analysis of mechanism of small molecule IAP inhibitors. J. Biol. Chem. 279: 48168-48176
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 48168-48176
-
-
Wang, Z.1
Cuddy, M.2
Samuel, T.3
Welsh, K.4
Schimmer, A.5
Hanaii, F.6
Houghten, R.7
Pinilla, C.8
Reed, J.C.9
-
62
-
-
0035072535
-
Pro-caspase-3 overexpression sensitises ovarian cancer cells to proteasome inhibitors
-
Tenev T, Marani M, McNeish I and Lemoine NR (2001) Pro-caspase-3 overexpression sensitises ovarian cancer cells to proteasome inhibitors 8: 256-264
-
(2001)
, vol.8
, pp. 256-264
-
-
Tenev, T.1
Marani, M.2
McNeish, I.3
Lemoine, N.R.4
-
63
-
-
0142188706
-
Coexistence of high levels of apoptotic signaling and inhibitor of apoptosis proteins in human tumor cells: Implication for cancer specific therapy
-
Yang L, Cao Z, Yan H and Wood WC (2003) Coexistence of high levels of apoptotic signaling and inhibitor of apoptosis proteins in human tumor cells: implication for cancer specific therapy. Cancer Res. 63: 6815-6824
-
(2003)
Cancer Res.
, vol.63
, pp. 6815-6824
-
-
Yang, L.1
Cao, Z.2
Yan, H.3
Wood, W.C.4
-
64
-
-
2542431137
-
Caspase-dependent regulation of histone deacetylase 4 nuclear-cytoplasmic shuttling promotes apoptosis
-
Paroni G, Mizzau M, Henderson C, Del Sal G, Schneider C and Brancolini C (2004) Caspase-dependent regulation of histone deacetylase 4 nuclear-cytoplasmic shuttling promotes apoptosis. Mol. Biol. Cell 15: 2804-2818
-
(2004)
Mol. Biol. Cell
, vol.15
, pp. 2804-2818
-
-
Paroni, G.1
Mizzau, M.2
Henderson, C.3
Del Sal, G.4
Schneider, C.5
Brancolini, C.6
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