Conformational change and mitochondrial translocation of Bax accompany proteasome inhibitor-induced apoptosis of chronic lymphocytic leukemic cells

Oncogene

Volumn 22, Issue 17, 2003, Pages 2643-2654

  Dewson, Grant ^a   Snowden, Roger T ^a   Almond, Jason B ^a   Dyer, Martin J S ^a   Cohen, Gerald M ^a  

^a UNIVERSITY OF LEICESTER   (United Kingdom)

Author keywords

Bax; Chronic lymphocytic leukemia; Proteasome inhibitors

Indexed keywords

ANTINEOPLASTIC AGENT; BENZYLOXYCARBONYLLEUCYLLEUCYLLEUCINAL; CASPASE; CHLORAMBUCIL; CYTOCHROME C; FLUDARABINE; LACTACYSTIN; PREDNISOLONE; PROTEASOME INHIBITOR; PROTEIN BAX; PROTEIN BCL 2; UBIQUITIN;

APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME INHIBITION; HUMAN; HUMAN CELL; IN VITRO STUDY; LYMPHATIC LEUKEMIA; MEMBRANE POTENTIAL; MITOCHONDRIAL MEMBRANE; MITOCHONDRION; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN EXPRESSION; PROTEIN FAMILY; PROTEIN LOCALIZATION; PROTEIN TRANSPORT;

APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; BH3 INTERACTING DOMAIN DEATH AGONIST PROTEIN; CARRIER PROTEINS; CYSTEINE ENDOPEPTIDASES; CYTOCHROME C GROUP; HUMANS; IMMUNOHISTOCHEMISTRY; LEUKEMIA, B-CELL, CHRONIC; MITOCHONDRIA; MULTIENZYME COMPLEXES; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEIN CONFORMATION; PROTEIN TRANSPORT; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-BCL-2; UBIQUITIN;

EID: 0037516876     PISSN: 09509232     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.onc.1206326     Document Type: Article

References (71)

1. Adams J. (2002). Curr. Opin. Chem. Biol., 6, 493-500.
2. Adams J and Elliott PJ. (2000). Oncogene, 19, 6687-6692.
3. Almond JB and Cohen GM. (2002). Leukemia, 16, 433-443.
4. Almond JB, Snowden RT, Hunter A, Dinsdale D, Cain K and Cohen GM. (2001). Leukemia, 15, 1388-1397.
5. An B, Goldfarb RH, Siman R and Dou QP. (1998). Cell Death Differ., 5, 1062-1075.
6. Antonsson B, Montessuit S, Sanchez B and Martinou JC. (2001). J. Biol. Chem., 276, 11615-11623.
7. Bannerji R and Byrd JC. (2000). Curr. Opin. Oncol., 12, 22-29.
8. Barragan M, Bellosillo B, Campas C, Colomer D, Pons G and Gil J. (2002). Blood, 99, 2969-2976.
9. Baumeister W, Walz J, Zuhl F and Seemuller E. (1998). Cell, 92, 367-380.
10. Bosanquet AG, Sturm I, Wieder T, Essmann F, Bosanquet MI, Head DJ, Dorken B and Daniel PT. (2002). Leukemia, 16, 1035-1044.
11. Bratton SB, Walker G, Srinivasula SM, Sun XM, Butterworth M, Alnemri ES and Cohen GM. (2001). EMBO J., 20, 9981009.
12. Breitschopf K, Zeiher AM and Dimmeler S. (2000). J. Biol. Chem., 275, 21648-21652.
13. Cain K, Brown DG, Langlais C and Cohen GM. (1999). J. Biol. Chem., 274, 22686-22692.
14. Chandra J, Niemer I, Gilbreath J, Kliche KO, Andreeff M, Freireich EJ, Keating M and McConkey DJ. (1998). Blood, 92, 4220-4229.
15. Chang YC, Lee YS, Tejima T, Tanaka K, Omura S, Heintz NH, Mitsui Y and Magae J. (1998). Cell Growth Differ., 9, 79-84.
16. Ciechanover A. (1994). Cell, 79, 13-21.
17. Cohen GM. (1997). Biochem. J., 326, 1-16.
18. Delic J, Masdehors P, Omura S, Cosset JM, Dumont J, Binet JL and Magdelenat H. (1998). Br. J. Cancer, 77, 1103-1107.
19. Deng Y, Lin Y and Wu X. (2002). Genes Dev., 16, 33-45.
20. Dewson G, Cohen GM and Wardlaw AJ. (2001). Blood, 98, 2239-2247.
21. Dou QP and Li B. (1999). Drug Resist. Update, 2, 215-223.
22. Drexler HC. (1997). Proc. Natl. Acad. Sci. USA, 94, 855-860.
23. Earnshaw WC, Martins LM and Kaufmann SH. (1999). Annu. Rev. Biochem., 68, 383-424.
24. Eskes R, Antonsson B, Osen-Sand A, Montessuit S, Richter C, Sadoul R, Mazzei G, Nichols A and Martinou JC. (1998). J. Cell Biol., 143, 217-224.
25. Ghatan S, Larner S, Kinoshita Y, Hetman M, Patel L, Xia Z, Youle RJ and Morrison RS. (2000). J. Cell Biol., 150, 335-347.
26. Gilmore AP, Metcalfe AD, Romer LH and Streuli CH. (2000). J. Cell Biol., 149, 431-446.
27. Goping IS, Gross A, Lavoie JN, Nguyen M, Jemmerson R, Roth K, Korsmeyer SJ and Shore GC. (1998). J. Cell Biol., 143, 207-215.
28. Gross A, Jockel J, Wei MC and Korsmeyer SJ. (1998). EMBO J., 17, 3878-3885.
29. Hideshima T, Richardson P, Chauhan D, Palombella VJ, Elliott PJ, Adams J and Anderson KC. (2001). Cancer Res., 61, 3071-3076.
30. Hsu YT, Wolter KG and Youle RJ. (1997). Proc. Natl. Acad. Sci. USA, 94, 3668-3672.
31. Hsu YT and Youle RJ. (1997). J. Biol. Chem., 272, 13829-13834.
32. Hsu YT and Youle RJ. (1998). J. Biol. Chem., 273, 10777-10783.
33. Jurgensmeier JM, Xie Z, Deveraux Q, Ellerby L, Bredesen D and Reed JC. (1998). Proc. Natl. Acad. Sci. USA, 95, 4997-5002.
34. Kalil N and Cheson BD. (1999). Oncologist, 4, 352-369.
35. Kitada S, Krajewska M, Zhang X, Scudiero D, Zapata JM, Wang HG, Shabaik A, Tudor G, Krajewski S, Myers TG, Johnson GS, Sausville EA and Reed JC. (1998). Am. J. Pathol., 152, 51-61.
36. Kluck RM, Bossy-Wetzel E, Green DR and Newmeyer DD. (1997). Science, 275, 1132-1136.
37. Li B and Dou QP. (2000). Proc. Natl. Acad. Sci. USA, 97, 3850-3855.
38. Li P, Nijhawan D, Budihardjo I, Srinivasula SM, Ahmad M, Alnemri ES and Wang X. (1997). Cell, 91, 479-489.
39. Lindsten T, Ross AJ, King A, Zong WX, Rathmell JC, Shiels HA, Ulrich E, Waymire KG, Mahar P, Frauwirth K, Chen Y, Wei M, Eng VM, Adelman DM, Simon MC, Ma A, Golden JA, Evan G, Korsmeyer SJ, MacGregor GR and Thompson CB. (2000). Mol. Cell, 6, 1389-1399.
40. Lopes UG, Erhardt P, Yao R and Cooper GM. (1997). J. Biol. Chem., 272, 12893-12896.
41. MacFarlane M, Ahmad M, Srinivasula SM, FernandesAlnemri T, Cohen GM and Alnemri ES. (1997). J. Biol. Chem., 272, 25417-25420.
42. MacFarlane M, Cohen GM and Dickens M. (2000). Biochem. J., 348, 93-101.
43. MacFarlane M, Harper N, Snowden RT, Dyer M J, Barnett GA, Pringle JH and Cohen GM. (2002). Oncogene, 21, 6809-6818.
44. Maianski NA, Mul FP, van Buul JD, Roos D and Kuijpers TW. (2002). Blood, 99, 672-679.
45. Makin GW, Corfe BM, Griffiths GJ, Thistlethwaite A, Hickman JA and Dive C. (2001). EMBO J., 20, 6306-6315.
46. Marshansky V, Wang X, Bertrand R, Luo H, Duguid W, Chinnadurai G, Kanaan N, Vu MD and Wu J. (2001). J. Immunol., 166, 3130-3142.
47. Martinou JC and Green DR. (2001). Nat. Rev. Mol. Cell Biol., 2, 63-67.
48. Marzo I, Brenner C, Zamzami N, Jurgensmeier JM, Susin SA, Vieira HL, Prevost MC, Xie Z, Matsuyama S, Reed JC and Kroemer G. (1998). Science, 281, 2027-2031.
49. McConkey DJ, Chandra J, Wright S, Plunkett W, McDonnell TJ, Reed JC and Keating M. (1996). J. Immunol., 156, 2624-2630.
50. Merlin AB, Gabai VL, Yaglom J, Shifrin VI and Sherman MY. (1998). J. Biol. Chem., 273, 6373-6379.
51. Murray RZ and Norbury C. (2000). Anticancer Drugs, 11, 407-417.
52. Naujokat C, Sezer O, Zinke H, Leclere A, Hauptmann S and Possinger K. (2000). Eur. J. Haematol., 65, 221-236.
53. Nechushtan A, Smith CL, Hsu YT and Youle RJ. (1999). EMBO J., 18, 2330-2341.
54. Orlowski RZ. (1999) Cell Death Differ., 6, 303-313.
55. Penault-Llorca F, Bouabdallah R, Devilard E, Charton-Bain MC, Hassoun J, Birg F and Xerri L. (1998). Pathol. Res. Pract., 194, 457-464.
56. Pepper C, Hoy T and Bentley P. (1998). Leukemia Lymphoma, 28, 355-361.
57. Pepper C, Thomas A, Hoy T and Bentley P. (1999). Br. J. Haematol., 104, 581-588.
58. Putcha GV, Deshmukh M and Johnson Jr EM. (1999). J. Neurosci., 19, 7476-7485.
59. Reed JC. (1998). Semin. Hematol., 35, 3-13.
60. Rossé T, Olivier R, Monney L, Rager M, Conus S, Fellay I, Jansen B and Borner C. (1998). Nature, 391, 496-499.
61. Scaduto Jr RC and Grotyohann LW. (1999). Biophys. J., 76, 469-477.
62. Shimizu S, Narita M and Tsujimoto Y. (1999). Nature, 399, 483-487.
63. Shinohara K, Tomioka M, Nakano H, Tone S, Ito H and Kawashima S. (1996). Biochem. J., 317, 385-388.
64. Sun XM, MacFarlane M, Zhuang J, Wolf BB, Green DR and Cohen GM. (1999). J. Biol. Chem., 274, 5053-5060.
65. Suzuki M, Youle RJ and Tjandra N. (2000). Cell, 103, 645-654.
66. Tsubuki S, Saito Y, Tomioka M, Ito H and Kawashima S. (1996) J. Biochem. (Tokyo), 119, 572-576.
67. Tsuruta F, Masuyama N and Gotoh Y. (2002). J. Biol. Chem., 277, 14040-14047.
68. Van Loo G, Saelens X, Van Gurp M, MacFarlane M, Martin SJ and Vandenabeele P. (2002). Cell Death Differ., 9, 1031-1042.
69. Wei MC, Zong WX, Cheng EH, Lindsten T, Panoutsakopoulou V, Ross AJ, Roth KA, MacGregor GR, Thompson CB and Korsmeyer SJ. (2001). Science, 292, 727-730.
70. Wolter KG, Hsu YT, Smith CL, Nechushtan A, Xi XG and Youle RJ. (1997). J. Cell Biol., 139, 1281-1292.
71. Yamaguchi H and Wang HG. (2001). Oncogene, 20, 7779-7786.