Proteasome inhibitor-induced apoptosis of glioma cells involves the processing of multiple caspases and cytochrome c release

Journal of Neurochemistry

Volumn 75, Issue 6, 2000, Pages 2288-2297

  Wagenknecht, B ^a   Hermisson, M ^a   Groscurth, P ^a   Liston, P ^a   Krammer, P H ^a   Weller, M ^a  

^a UNIVERSITY OF TÜBINGEN   (Germany)

Author keywords

Apoptosis; Glioma; MG132; Proteasome

Indexed keywords

BENZYLOXYCARBONYLLEUCYLLEUCYLLEUCINAL; CASPASE 2; CASPASE 3; CASPASE 7; CASPASE 8; CASPASE 9; CASPASE INHIBITOR; CYCLOHEXIMIDE; CYTOCHROME C; LACTACYSTIN; PROTEASOME INHIBITOR; PROTEIN BCL 2; PROTEIN SYNTHESIS INHIBITOR;

APOPTOSIS; ARTICLE; CELL VACUOLE; CONTROLLED STUDY; CYTOPLASM VESICLE; DRUG EFFECT; ENZYME RELEASE; GLIOBLASTOMA; HUMAN; HUMAN CELL; MITOCHONDRION; PRIORITY JOURNAL; PROTEIN DETERMINATION; PROTEIN EXPRESSION; PROTEIN PROCESSING; ROUGH ENDOPLASMIC RETICULUM;

ACETYLCYSTEINE; ANIMALS; ANTI-BACTERIAL AGENTS; ANTIGENS, CD95; ANTINEOPLASTIC AGENTS; APOPTOSIS; CASPASES; CELL SURVIVAL; CYCLOHEXIMIDE; CYSTEINE ENDOPEPTIDASES; CYSTEINE PROTEINASE INHIBITORS; CYTOCHROME C GROUP; DOSE-RESPONSE RELATIONSHIP, DRUG; FAS LIGAND PROTEIN; GLIOMA; HUMANS; LACTAMS; LEUPEPTINS; MEMBRANE GLYCOPROTEINS; MICE; MITOCHONDRIA; MULTIENZYME COMPLEXES; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTEIN SYNTHESIS INHIBITORS; PROTO-ONCOGENE PROTEINS C-BCL-2; TRANSGENES; TUMOR CELLS, CULTURED;

EUKARYOTA;

EID: 0033773607     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1471-4159.2000.0752288.x     Document Type: Article

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