Molecular sequelae of proteasome inhibition in human multiple myeloma cells

Proceedings of the National Academy of Sciences of the United States of America

Volumn 99, Issue 22, 2002, Pages 14374-14379

  Mitsiades, Nicholas ^a   Mitsiades, Constantine S ^a   Poulaki, Vassiliki ^a   Chauhan, Dharminder ^a   Fanourakis, Galinos ^a   Gu, Xuesong ^a,b   Bailey, Charles ^b   Joseph, Marie ^b   Libermann, Towia A ^a,b   Treon, Steven P ^a   Munshi, Nikhil C ^a   Richardson, Paul G ^a   Hideshima, Teru ^a   Anderson, Kenneth C ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

^b HARVARD INSTITUTES OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BORTEZOMIB; CASPASE 8; CASPASE 9; CYTOCHROME C; FAS ANTIGEN; HEAT SHOCK PROTEIN 90; PROTEIN BCL 2; PROTEIN KINASE B; SOMATOMEDIN C; STRESS ACTIVATED PROTEIN KINASE;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CONTROLLED STUDY; DOWN REGULATION; ENZYME ACTIVATION; ENZYME RELEASE; GENE EXPRESSION PROFILING; GENE OVEREXPRESSION; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; MOLECULAR DYNAMICS; MOLECULAR MECHANICS; MULTIPLE MYELOMA; MYELOMA CELL; PRIORITY JOURNAL; PROTEIN DEGRADATION; SIGNAL TRANSDUCTION; SURVIVAL RATE; UPREGULATION;

ANTINEOPLASTIC AGENTS; APOPTOSIS; BORONIC ACIDS; CYSTEINE ENDOPEPTIDASES; CYSTEINE PROTEINASE INHIBITORS; DOWN-REGULATION; GENE EXPRESSION PROFILING; HEAT-SHOCK PROTEINS; HUMANS; INSULIN-LIKE GROWTH FACTOR I; MULTIENZYME COMPLEXES; MULTIPLE MYELOMA; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-AKT; PYRAZINES; SIGNAL TRANSDUCTION; TRANSCRIPTION, GENETIC; TUMOR CELLS, CULTURED; UBIQUITIN;

EID: 0242496212     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.202445099     Document Type: Article

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